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The map label for this gene is ctaE [H]

Identifier: 187927330

GI number: 187927330

Start: 237823

End: 238683

Strand: Direct

Name: ctaE [H]

Synonym: Rpic_0223

Alternate gene names: 187927330

Gene position: 237823-238683 (Clockwise)

Preceding gene: 187927329

Following gene: 187927332

Centisome position: 6.03

GC content: 62.37

Gene sequence:

>861_bases
ATGAGTGCGAATCGAGCAAACGCTCCGTACTACTTCGTGCCCGGGCCCTCGCGGCATCCGATTACGGCAAGCCTCGGCCT
GCTGATCGTGCTGTTGAGCTCCGCTGCATGGGTGAATGCCCAGCCGTGGGCCCCGTGGACGTTCCTGGTCGGGCTGCTGT
GGTTCCTCTTTGTGCTGCGCGCGTGGTTTGCCGACGCCATCTCCGAATCCGAGACCGGCAAGTACGGCGACCGCGTGGAT
GCCTCGTTCCGCTGGTCGATGAGCTGGTTCATCTTCTCGGAAGTGATGTTCTTCGCGGCGTTCTTCGGCGCGCTGTTCTA
TGCCCGCACGATCGCCATGCCGTGGCTGGGCGATCTGAACAACAAGCTGCTGTGGCCGGACTTTAACGCGCTATGGCCGA
ACGCTGGCCCCGCCGGCACGGTATCACCGTTCACGACGATGGGCCCGTGGCCGATCCCGACCATCAACACGGCGCTGCTG
CTGACCTCCGGTGTGACGCTCACGTGGGCACATCATGCGCTGCGTGAAGGCAAGCGCGCGCAGGTCATCCAGGGTCTGCT
GCTGACGATCCTCCTGGGCTTTACGTTCATGGGCTTCCAGGCGTTCGAATACATCCACGCCTATCACGAACTGAACCTGA
AGCTGACCTCGGGCATCTACGGTTCGACGTTCTTCCTGCTGACGGGCTTCCACGGCTTCCACGTGACCATGGGCGCCATC
ATGCTGTCGGTGGTGCTGGGGCGTGTGATCAAGGGCCACTTCACGCCGGAGCATCACTTCGCATTCGAAGGCGCCGCGTG
GTACTGGCACTTTGTGGACGTGGTGTGGCTGGGCCTGTACGTGGTGGTGTACTGGCTGTAA

Upstream 100 bases:

>100_bases
GTGGTCGGTTGAGGATTGAGCAGGTTGAGGAGACGGCCCCGCAGCATGGGCCGGGCAATATCGAGTGGATTCTTAAAAAA
ATAGAGCTGGAGAAAAAGAG

Downstream 100 bases:

>100_bases
GACAGCATGGGAATGGGGCAGCGCAGCGCCGCCCCGTAGCACGGCCCACGACAGGTGAAGACAATGCCGCAGACGGGACA
CCGCTGCGGCGTTTTCGTTT

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSANRANAPYYFVPGPSRHPITASLGLLIVLLSSAAWVNAQPWAPWTFLVGLLWFLFVLRAWFADAISESETGKYGDRVD
ASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKLLWPDFNALWPNAGPAGTVSPFTTMGPWPIPTINTALL
LTSGVTLTWAHHALREGKRAQVIQGLLLTILLGFTFMGFQAFEYIHAYHELNLKLTSGIYGSTFFLLTGFHGFHVTMGAI
MLSVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Sequences:

>Translated_286_residues
MSANRANAPYYFVPGPSRHPITASLGLLIVLLSSAAWVNAQPWAPWTFLVGLLWFLFVLRAWFADAISESETGKYGDRVD
ASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKLLWPDFNALWPNAGPAGTVSPFTTMGPWPIPTINTALL
LTSGVTLTWAHHALREGKRAQVIQGLLLTILLGFTFMGFQAFEYIHAYHELNLKLTSGIYGSTFFLLTGFHGFHVTMGAI
MLSVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
>Mature_285_residues
SANRANAPYYFVPGPSRHPITASLGLLIVLLSSAAWVNAQPWAPWTFLVGLLWFLFVLRAWFADAISESETGKYGDRVDA
SFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKLLWPDFNALWPNAGPAGTVSPFTTMGPWPIPTINTALLL
TSGVTLTWAHHALREGKRAQVIQGLLLTILLGFTFMGFQAFEYIHAYHELNLKLTSGIYGSTFFLLTGFHGFHVTMGAIM
LSVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=226, Percent_Identity=45.575221238938, Blast_Score=168, Evalue=6e-42,
Organism=Escherichia coli, GI1786633, Length=136, Percent_Identity=34.5588235294118, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6226542, Length=227, Percent_Identity=35.6828193832599, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32271; Mature: 32140

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANRANAPYYFVPGPSRHPITASLGLLIVLLSSAAWVNAQPWAPWTFLVGLLWFLFVLR
CCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AWFADAISESETGKYGDRVDASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLN
HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NKLLWPDFNALWPNAGPAGTVSPFTTMGPWPIPTINTALLLTSGVTLTWAHHALREGKRA
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHH
QVIQGLLLTILLGFTFMGFQAFEYIHAYHELNLKLTSGIYGSTFFLLTGFHGFHVTMGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCHHHHHHHHH
MLSVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SANRANAPYYFVPGPSRHPITASLGLLIVLLSSAAWVNAQPWAPWTFLVGLLWFLFVLR
CCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AWFADAISESETGKYGDRVDASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLN
HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NKLLWPDFNALWPNAGPAGTVSPFTTMGPWPIPTINTALLLTSGVTLTWAHHALREGKRA
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHH
QVIQGLLLTILLGFTFMGFQAFEYIHAYHELNLKLTSGIYGSTFFLLTGFHGFHVTMGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCHHHHHHHHH
MLSVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]