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The map label for this gene is coaX [H]

Identifier: 187927274

GI number: 187927274

Start: 183629

End: 184510

Strand: Reverse

Name: coaX [H]

Synonym: Rpic_0166

Alternate gene names: 187927274

Gene position: 184510-183629 (Counterclockwise)

Preceding gene: 187927275

Following gene: 187927273

Centisome position: 4.68

GC content: 70.41

Gene sequence:

>882_bases
ATGACGCGCCTGAAGGTGTCCGCCGCGCACGCCGCCCCCGCCCGTCCGCTCTTGCTGATCGACGCAGGGAACACGCGCAT
CAAATGGGCGTGGATTGCCGGCGGTGCCGATGCCGAACCCGCGCTGCCCGAGGAACCCGGCGGCACACCCTGGCAGCATG
CCGGCGCCCGCGCGCATGATCGATTGGCCGAGCTGGTGGAAGACTGGCGCGATTGCCACGCCTCCGGCGTTGCGCCGCCC
GAGGTATGGATCAGCGCGGTGGCTGGCCCCGCACTGCGCGATGCGCTCACCGCACGCATCGCCCGCGTGTTCGACGGAGC
GCGCGTGTGCATTGCGGCATCGGAAGACGCCACCGCCGGCCTGCGCAATGGGTATCGCGACCCAACGCAACTCGGCACCG
ACCGGTGGATCGGTGCGGTCGGTGCACGCCATCTGTGGCCCGACACCGCCCTGCTGCTCGTGACGGCCGGCACGGCCACC
ACGCTCGACATCGTCACACCCGATGGCTTGTTTGCCGGCGGCCTGATCCTGCCCGGCCTCACATTGATGATGCACGCGTT
GTCACGCAACACGGCGCAGTTGCCCGAAGTGGACGTCGGCTACCTGAGCGCGGGCGACGTTGTGGCGCCGCCCTGGGCCG
ACAATACGCAGGACGCCATCGCGCTGGGCTGCGTCATCGCCCAGGCAGGTGCAATTGCACAGACGTGGCAGGCACTGCAG
AAGCAATACCCCGGCCCGGCACGCTGCGTGCTGAGCGGCGGGGCGCGCGCCGCACTGGGGCCGCATCTGCGCATGCCGTT
CCAGATGCACGATAATCTCGTGCTGCTCGGCCTGCAGGTGCTGGCGCGCGCGCGCCGGGAAGGCGCCGCGACGCTGGCCT
AG

Upstream 100 bases:

>100_bases
GAATCGACGCACAAGGCCGTCTGGCGATTGAATCGGGCGGACGTGTGCAGTGGATTCACAGCGGCGAGGTCTCCTTGCGC
AGCGCAGATGCGGAGCAGCC

Downstream 100 bases:

>100_bases
CCTCAGTCGGCCGGGCTGCAGTTTCCCATCTGACGTCTTATCGTTGTTGCCGCTGTGTTCCTGCATTCCGAGCCCCCGTC
CGAATCCACGTCCGTTCGCA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTRLKVSAAHAAPARPLLLIDAGNTRIKWAWIAGGADAEPALPEEPGGTPWQHAGARAHDRLAELVEDWRDCHASGVAPP
EVWISAVAGPALRDALTARIARVFDGARVCIAASEDATAGLRNGYRDPTQLGTDRWIGAVGARHLWPDTALLLVTAGTAT
TLDIVTPDGLFAGGLILPGLTLMMHALSRNTAQLPEVDVGYLSAGDVVAPPWADNTQDAIALGCVIAQAGAIAQTWQALQ
KQYPGPARCVLSGGARAALGPHLRMPFQMHDNLVLLGLQVLARARREGAATLA

Sequences:

>Translated_293_residues
MTRLKVSAAHAAPARPLLLIDAGNTRIKWAWIAGGADAEPALPEEPGGTPWQHAGARAHDRLAELVEDWRDCHASGVAPP
EVWISAVAGPALRDALTARIARVFDGARVCIAASEDATAGLRNGYRDPTQLGTDRWIGAVGARHLWPDTALLLVTAGTAT
TLDIVTPDGLFAGGLILPGLTLMMHALSRNTAQLPEVDVGYLSAGDVVAPPWADNTQDAIALGCVIAQAGAIAQTWQALQ
KQYPGPARCVLSGGARAALGPHLRMPFQMHDNLVLLGLQVLARARREGAATLA
>Mature_292_residues
TRLKVSAAHAAPARPLLLIDAGNTRIKWAWIAGGADAEPALPEEPGGTPWQHAGARAHDRLAELVEDWRDCHASGVAPPE
VWISAVAGPALRDALTARIARVFDGARVCIAASEDATAGLRNGYRDPTQLGTDRWIGAVGARHLWPDTALLLVTAGTATT
LDIVTPDGLFAGGLILPGLTLMMHALSRNTAQLPEVDVGYLSAGDVVAPPWADNTQDAIALGCVIAQAGAIAQTWQALQK
QYPGPARCVLSGGARAALGPHLRMPFQMHDNLVLLGLQVLARARREGAATLA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 30707; Mature: 30576

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLKVSAAHAAPARPLLLIDAGNTRIKWAWIAGGADAEPALPEEPGGTPWQHAGARAHD
CCEEEEECCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHCCCHHHH
RLAELVEDWRDCHASGVAPPEVWISAVAGPALRDALTARIARVFDGARVCIAASEDATAG
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHH
LRNGYRDPTQLGTDRWIGAVGARHLWPDTALLLVTAGTATTLDIVTPDGLFAGGLILPGL
HHCCCCCHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCHHCCCHHHHHH
TLMMHALSRNTAQLPEVDVGYLSAGDVVAPPWADNTQDAIALGCVIAQAGAIAQTWQALQ
HHHHHHHHCCCCCCCCCCCCEECCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
KQYPGPARCVLSGGARAALGPHLRMPFQMHDNLVLLGLQVLARARREGAATLA
HHCCCHHEEEECCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRLKVSAAHAAPARPLLLIDAGNTRIKWAWIAGGADAEPALPEEPGGTPWQHAGARAHD
CEEEEECCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHCCCHHHH
RLAELVEDWRDCHASGVAPPEVWISAVAGPALRDALTARIARVFDGARVCIAASEDATAG
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHH
LRNGYRDPTQLGTDRWIGAVGARHLWPDTALLLVTAGTATTLDIVTPDGLFAGGLILPGL
HHCCCCCHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCHHCCCHHHHHH
TLMMHALSRNTAQLPEVDVGYLSAGDVVAPPWADNTQDAIALGCVIAQAGAIAQTWQALQ
HHHHHHHHCCCCCCCCCCCCEECCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
KQYPGPARCVLSGGARAALGPHLRMPFQMHDNLVLLGLQVLARARREGAATLA
HHCCCHHEEEECCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]