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The map label for this gene is can [H]

Identifier: 187927235

GI number: 187927235

Start: 147143

End: 147823

Strand: Reverse

Name: can [H]

Synonym: Rpic_0127

Alternate gene names: 187927235

Gene position: 147823-147143 (Counterclockwise)

Preceding gene: 187927236

Following gene: 187927234

Centisome position: 3.75

GC content: 59.91

Gene sequence:

>681_bases
ATGCCACAACGCATCAAAGAGCTGTTCGAGAACAACCGGAAGTGGGTCGAGCGGGTCAACGCTGAAGACCCGGCGTTTTT
CTCGAATCTGGCCAATCAGCAGAACCCGGAATACCTCTGGATCGGCTGCTCGGATTCGCGCGTGCCGGCCAACCAGATCA
TCGGTCTGCCGCCGGGCGAGGTGTTCGTCCACCGCAACATCGCCAACGTCGTGGTGCACTCGGACTTGAACTGCCTGTCG
GTGCTGCAGTTTGCGGTGGAAGTGCTGAAGATCCGGCACATCACGGTGGTGGGTCACTACGGCTGTTCTGGCGTGAAGGC
CGCACTGACCAAGCAGCGCTTTGGCCTGGCTGACAACTGGATTCGTCACGTGCGGGATGTGGCCGAGCAGCATGAAACGT
ATCTCGGTACGGTGGTCCGCGAGCAGGATCAGCACGACAGGCTGTGCGAGCTGAACGTGATCCATCAGGTCAACAACGTG
TGCCTGACGACGATCGTGCAGGACGCCTGGGATCGCGGGCAGCCGCTGACGGTTCATGGCTGGATCTACGGCGTGAAGGA
CGGGATGCTGCGCAATCTGGGGATGGCGGCGAATTCGAATGAGGAGCTGCATGCGCAGCTTGCTGATGCTTGGTTGAACT
ATGGGAAGGAAGGGAGTGTGCCTAGTCCGGTGGGGTTTTGA

Upstream 100 bases:

>100_bases
TCGTCAATCGCTACGGCGCGAGCGCGCCCGACAACGCAGCACAAGACAACACGACGCTGCAGCGCGCCGCCGCTTAACCC
TCTCAACACGACGGGAAACC

Downstream 100 bases:

>100_bases
TTTCTTTTGAGTTTGGGGTGGGTTGTTTTGTTTTCGGTTCATCCCTTGTTTCATCCCCTGCCGGGGCTGACTCACTTTCT
TTGTCTTGCCAAAGAAAGTA

Product: Carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPQRIKELFENNRKWVERVNAEDPAFFSNLANQQNPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLNCLS
VLQFAVEVLKIRHITVVGHYGCSGVKAALTKQRFGLADNWIRHVRDVAEQHETYLGTVVREQDQHDRLCELNVIHQVNNV
CLTTIVQDAWDRGQPLTVHGWIYGVKDGMLRNLGMAANSNEELHAQLADAWLNYGKEGSVPSPVGF

Sequences:

>Translated_226_residues
MPQRIKELFENNRKWVERVNAEDPAFFSNLANQQNPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLNCLS
VLQFAVEVLKIRHITVVGHYGCSGVKAALTKQRFGLADNWIRHVRDVAEQHETYLGTVVREQDQHDRLCELNVIHQVNNV
CLTTIVQDAWDRGQPLTVHGWIYGVKDGMLRNLGMAANSNEELHAQLADAWLNYGKEGSVPSPVGF
>Mature_225_residues
PQRIKELFENNRKWVERVNAEDPAFFSNLANQQNPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLNCLSV
LQFAVEVLKIRHITVVGHYGCSGVKAALTKQRFGLADNWIRHVRDVAEQHETYLGTVVREQDQHDRLCELNVIHQVNNVC
LTTIVQDAWDRGQPLTVHGWIYGVKDGMLRNLGMAANSNEELHAQLADAWLNYGKEGSVPSPVGF

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=199, Percent_Identity=53.2663316582915, Blast_Score=234, Evalue=3e-63,
Organism=Escherichia coli, GI1786534, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=198, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25484; Mature: 25353

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQRIKELFENNRKWVERVNAEDPAFFSNLANQQNPEYLWIGCSDSRVPANQIIGLPPGE
CCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHEECCCCCC
VFVHRNIANVVVHSDLNCLSVLQFAVEVLKIRHITVVGHYGCSGVKAALTKQRFGLADNW
EEEECCHHHHHEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCHHHH
IRHVRDVAEQHETYLGTVVREQDQHDRLCELNVIHQVNNVCLTTIVQDAWDRGQPLTVHG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
WIYGVKDGMLRNLGMAANSNEELHAQLADAWLNYGKEGSVPSPVGF
EEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQRIKELFENNRKWVERVNAEDPAFFSNLANQQNPEYLWIGCSDSRVPANQIIGLPPGE
CHHHHHHHHCCHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHEECCCCCC
VFVHRNIANVVVHSDLNCLSVLQFAVEVLKIRHITVVGHYGCSGVKAALTKQRFGLADNW
EEEECCHHHHHEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCHHHH
IRHVRDVAEQHETYLGTVVREQDQHDRLCELNVIHQVNNVCLTTIVQDAWDRGQPLTVHG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
WIYGVKDGMLRNLGMAANSNEELHAQLADAWLNYGKEGSVPSPVGF
EEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]