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The map label for this gene is coaX

Identifier: 187918390

GI number: 187918390

Start: 543984

End: 544781

Strand: Direct

Name: coaX

Synonym: BH0527

Alternate gene names: 187918390

Gene position: 543984-544781 (Clockwise)

Preceding gene: 187918389

Following gene: 187918394

Centisome position: 58.98

GC content: 29.95

Gene sequence:

>798_bases
TTGAGAATATTGATGAATAAATTTGTTGGTGCAGTTCAGTTAATCATTGATATTGGAAACACAAGTATATCTTTTGCATT
GTATAGACTGGACAAAATGCAGATATATTGCAAGCTTGGCACAAAACGTGATTTGAGCTTTAAGGAGCTTTATAAGTTTC
TTAAGGTTAAATTTGACTACAAGGTTGATCAAGTGTTTGTAAGTAGTGTTGTACCTGTTATTGACACAGTACTTATCAAT
GCAATTGTTTCCCTTTATAAGGTAAATCCTTTATTCATTCGATTTGATTTAAGTTATGACTTAAGTTTTAATCTTTATAA
TAACAATAGATTCGTATTAGGGTCGGATGTTTTTGCAAATCTTGTTGGAGCTATTGAGTATTATAATATTAATGATGCTT
TGGTAGTAGATCTTGGAACAGCTTGTACTATTTTTGCGATTAGCAGAAGGGAAGGTATACTTGGTGGTCTTATTAATGGT
GGGCCATTCACAGATTTGAATGCATTAATTCAGAATGCATATCTTTTAAATGATTTTAATCTTGCAGTACCAAAAAAATT
GCTAGGTTTATCAACTATTGATAGTGTAAATAGTGGTGTAATTTATCAGTATAAGTATTTAATAGAAGGCGTTTATCATG
AACTTAGACATAATTATGATAAGGAATTTAGATTGATAATTACAGGTGGAAATTCTTATTTAGTTTTACCTTTAATAAGC
GTGGATTTTATAGCTAATTTGTATTTGACCCTTGAAGGAATTAGGATTTTGGGAAATGCTTTTAAAGGTGATTATTAG

Upstream 100 bases:

>100_bases
TGGAGATATTATTCTGATAATAAGATATTGGTTTTAAAAATAACCCCTAAGAAATCTGATGATACAAAGATTCTCTTAAG
ATTTGATGATATAAAGGCAT

Downstream 100 bases:

>100_bases
TGCTTTTATTATGTGTTTTTTTAATAAAGGTTTTTATGATGCGTAATTATTAATATTATATTATGTGATATAAATTAAAT
TTTCTTGTTAATAATGCCTA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRILMNKFVGAVQLIIDIGNTSISFALYRLDKMQIYCKLGTKRDLSFKELYKFLKVKFDYKVDQVFVSSVVPVIDTVLIN
AIVSLYKVNPLFIRFDLSYDLSFNLYNNNRFVLGSDVFANLVGAIEYYNINDALVVDLGTACTIFAISRREGILGGLING
GPFTDLNALIQNAYLLNDFNLAVPKKLLGLSTIDSVNSGVIYQYKYLIEGVYHELRHNYDKEFRLIITGGNSYLVLPLIS
VDFIANLYLTLEGIRILGNAFKGDY

Sequences:

>Translated_265_residues
MRILMNKFVGAVQLIIDIGNTSISFALYRLDKMQIYCKLGTKRDLSFKELYKFLKVKFDYKVDQVFVSSVVPVIDTVLIN
AIVSLYKVNPLFIRFDLSYDLSFNLYNNNRFVLGSDVFANLVGAIEYYNINDALVVDLGTACTIFAISRREGILGGLING
GPFTDLNALIQNAYLLNDFNLAVPKKLLGLSTIDSVNSGVIYQYKYLIEGVYHELRHNYDKEFRLIITGGNSYLVLPLIS
VDFIANLYLTLEGIRILGNAFKGDY
>Mature_265_residues
MRILMNKFVGAVQLIIDIGNTSISFALYRLDKMQIYCKLGTKRDLSFKELYKFLKVKFDYKVDQVFVSSVVPVIDTVLIN
AIVSLYKVNPLFIRFDLSYDLSFNLYNNNRFVLGSDVFANLVGAIEYYNINDALVVDLGTACTIFAISRREGILGGLING
GPFTDLNALIQNAYLLNDFNLAVPKKLLGLSTIDSVNSGVIYQYKYLIEGVYHELRHNYDKEFRLIITGGNSYLVLPLIS
VDFIANLYLTLEGIRILGNAFKGDY

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_BORHD (B2S0M7)

Other databases:

- EMBL:   CP000048
- RefSeq:   YP_001883953.1
- EnsemblBacteria:   EBBORT00000006289
- GeneID:   6276429
- GenomeReviews:   CP000048_GR
- KEGG:   bhr:BH0527
- GeneTree:   EBGT00050000007230
- HOGENOM:   HBG354445
- OMA:   GTACTIF
- ProtClustDB:   PRK13326
- BioCyc:   BHER314723:BH0527-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 29945; Mature: 29945

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: ACT_SITE 116-116 BINDING 140-140 BINDING 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILMNKFVGAVQLIIDIGNTSISFALYRLDKMQIYCKLGTKRDLSFKELYKFLKVKFDY
CEEHHHHHHHHEEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHEEECC
KVDQVFVSSVVPVIDTVLINAIVSLYKVNPLFIRFDLSYDLSFNLYNNNRFVLGSDVFAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEECCCEEEEEHHHHHH
LVGAIEYYNINDALVVDLGTACTIFAISRREGILGGLINGGPFTDLNALIQNAYLLNDFN
HHHHEEEEECCCEEEEECCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHCCEEEECCC
LAVPKKLLGLSTIDSVNSGVIYQYKYLIEGVYHELRHNYDKEFRLIITGGNSYLVLPLIS
CCCCHHHHCCHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEHH
VDFIANLYLTLEGIRILGNAFKGDY
HHHHHHHHHHEEHHHEEHHHCCCCC
>Mature Secondary Structure
MRILMNKFVGAVQLIIDIGNTSISFALYRLDKMQIYCKLGTKRDLSFKELYKFLKVKFDY
CEEHHHHHHHHEEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHEEECC
KVDQVFVSSVVPVIDTVLINAIVSLYKVNPLFIRFDLSYDLSFNLYNNNRFVLGSDVFAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEECCCEEEEEHHHHHH
LVGAIEYYNINDALVVDLGTACTIFAISRREGILGGLINGGPFTDLNALIQNAYLLNDFN
HHHHEEEEECCCEEEEECCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHCCEEEECCC
LAVPKKLLGLSTIDSVNSGVIYQYKYLIEGVYHELRHNYDKEFRLIITGGNSYLVLPLIS
CCCCHHHHCCHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEHH
VDFIANLYLTLEGIRILGNAFKGDY
HHHHHHHHHHEEHHHEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA