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The map label for this gene is engA [H]

Identifier: 187918374

GI number: 187918374

Start: 518438

End: 519754

Strand: Direct

Name: engA [H]

Synonym: BH0508

Alternate gene names: 187918374

Gene position: 518438-519754 (Clockwise)

Preceding gene: 187918372

Following gene: 187918375

Centisome position: 56.21

GC content: 29.38

Gene sequence:

>1317_bases
TTGATTAATTCTAAAGTTCAAAATTATAAAAGTGTTCTTATTGCTGGCAGGCCAAACGTTGGAAAGTCTACTTTGTTTAA
TAAGCTTTTAAGCTCGAATAGGAGTATTACTGATGAGGTTTATGGAGTTACTAGGGATTTAGTAAAAGAGGTTTGCACAG
TAGATTCTTATAAGTTTTATTTGATTGATGCTGGTGGATTTACCCTTTTAAGGGATGAACTTAGTAGGATTGTGGTTAAT
AAAGTTATAAGTTTGCTTGATAGCATTGATTTAATCTTACTTGTTTTAGATGTAAATGAAATGTTATTAGAAGATTATGA
GCTTATTGAGAAGTTAAGAAAATATAGCGATAAGATAGTTTTGGTATTAAATAAAATAGATAGTAATCATAAGGAAGTTT
TGACTTATGAATTTCAAAAGTTGGGCTTTAAGAAGAGCTTTTTAGTTAGTGCTACTCATGGAAAGGGAATTAATAGCTTA
AGAATTTTTTTGAAAAACTCAGTGGGCAAATTGGCAAGTGAGGATAATACTGATGTTAAAATTGGTATTATAGGAAAGCC
AAATTCAGGCAAGTCGACTCTTATTAACTTTTTAGCTGGAGATGAGGTTTCAATTGTGTCTCCGATAGCTGGAACTACAA
GGGATTTTATTAAAGCAAGATTTCAAAGGAATGGTAAGATATTTGAGCTTATTGATACGGCTGGAATAAGGCGGAGAGCG
AGAGTAAATGAACTTGTTGAACATTATTCTGTAAGTAGAGCTTTAAGAGTAATTGATATGGTAGATATTGTCTTTTTGTT
AGTTGATGTTAAGGAAGAATTAACGGCTCAAGATAAGAAAATTGCACATTATGCAACTAAACGGGGGAAAGGGATTATTA
TTGTGTTTACCAAGTGGGATCTTGTAGATTCAAAGAGCGGTTATTTTGAGGCTTTAAAGAGTCGTGTTAAGTTTTTTTTT
CCAGTTTTAAGTTTTTCTCCCATATTAAAAATATCTGTTCATAAAAAAGTGGGGTTAGATAATCTTTTTAAAGAAGCAAT
TAAATTAAAAAAACAACTTGAACTTAAGATGAATACTTCTGATTTGAATAAGATGTTAAGTTTATGGATTAAGGATTATC
ATTTGAATGCTTCACATAAAGTTAAATATATGACTCAGATTAGTGTTAATCCTGTTAAGTTTATTTTATTTGCGAATAAA
ATAACTAATTTTCCAAATTCTTATTATAATTATTTAGTAAATAATATTCGTAAAATTGGTTATTATAATATTCCAATTTT
AATAGAACTGAGAGAAAAGACAAGAGACTTAAAGTGA

Upstream 100 bases:

>100_bases
TTTTTCCTTATCAATTAAGCATCCGTTTATAATTGGCATAAAGCTGTAATATTTGATATTATAATAGAAATACCTACATA
AAGAAAGAGGCAGGTTAGCT

Downstream 100 bases:

>100_bases
GATATATATTTTTATTTTTGATAGTTGGGAATCTAAATCTCTTTGCATTTGAAAATTTTCTCTATGATTTTAGCGTTAGA
GCAAATTATGCAAAATATTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MINSKVQNYKSVLIAGRPNVGKSTLFNKLLSSNRSITDEVYGVTRDLVKEVCTVDSYKFYLIDAGGFTLLRDELSRIVVN
KVISLLDSIDLILLVLDVNEMLLEDYELIEKLRKYSDKIVLVLNKIDSNHKEVLTYEFQKLGFKKSFLVSATHGKGINSL
RIFLKNSVGKLASEDNTDVKIGIIGKPNSGKSTLINFLAGDEVSIVSPIAGTTRDFIKARFQRNGKIFELIDTAGIRRRA
RVNELVEHYSVSRALRVIDMVDIVFLLVDVKEELTAQDKKIAHYATKRGKGIIIVFTKWDLVDSKSGYFEALKSRVKFFF
PVLSFSPILKISVHKKVGLDNLFKEAIKLKKQLELKMNTSDLNKMLSLWIKDYHLNASHKVKYMTQISVNPVKFILFANK
ITNFPNSYYNYLVNNIRKIGYYNIPILIELREKTRDLK

Sequences:

>Translated_438_residues
MINSKVQNYKSVLIAGRPNVGKSTLFNKLLSSNRSITDEVYGVTRDLVKEVCTVDSYKFYLIDAGGFTLLRDELSRIVVN
KVISLLDSIDLILLVLDVNEMLLEDYELIEKLRKYSDKIVLVLNKIDSNHKEVLTYEFQKLGFKKSFLVSATHGKGINSL
RIFLKNSVGKLASEDNTDVKIGIIGKPNSGKSTLINFLAGDEVSIVSPIAGTTRDFIKARFQRNGKIFELIDTAGIRRRA
RVNELVEHYSVSRALRVIDMVDIVFLLVDVKEELTAQDKKIAHYATKRGKGIIIVFTKWDLVDSKSGYFEALKSRVKFFF
PVLSFSPILKISVHKKVGLDNLFKEAIKLKKQLELKMNTSDLNKMLSLWIKDYHLNASHKVKYMTQISVNPVKFILFANK
ITNFPNSYYNYLVNNIRKIGYYNIPILIELREKTRDLK
>Mature_438_residues
MINSKVQNYKSVLIAGRPNVGKSTLFNKLLSSNRSITDEVYGVTRDLVKEVCTVDSYKFYLIDAGGFTLLRDELSRIVVN
KVISLLDSIDLILLVLDVNEMLLEDYELIEKLRKYSDKIVLVLNKIDSNHKEVLTYEFQKLGFKKSFLVSATHGKGINSL
RIFLKNSVGKLASEDNTDVKIGIIGKPNSGKSTLINFLAGDEVSIVSPIAGTTRDFIKARFQRNGKIFELIDTAGIRRRA
RVNELVEHYSVSRALRVIDMVDIVFLLVDVKEELTAQDKKIAHYATKRGKGIIIVFTKWDLVDSKSGYFEALKSRVKFFF
PVLSFSPILKISVHKKVGLDNLFKEAIKLKKQLELKMNTSDLNKMLSLWIKDYHLNASHKVKYMTQISVNPVKFILFANK
ITNFPNSYYNYLVNNIRKIGYYNIPILIELREKTRDLK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=28.6652078774617, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=42.8571428571429, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788919, Length=160, Percent_Identity=28.125, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=85, Percent_Identity=45.8823529411765, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=170, Percent_Identity=35.8823529411765, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50049; Mature: 50049

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSKVQNYKSVLIAGRPNVGKSTLFNKLLSSNRSITDEVYGVTRDLVKEVCTVDSYKFY
CCCCHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
LIDAGGFTLLRDELSRIVVNKVISLLDSIDLILLVLDVNEMLLEDYELIEKLRKYSDKIV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LVLNKIDSNHKEVLTYEFQKLGFKKSFLVSATHGKGINSLRIFLKNSVGKLASEDNTDVK
EEEECCCCCCHHHHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEE
IGIIGKPNSGKSTLINFLAGDEVSIVSPIAGTTRDFIKARFQRNGKIFELIDTAGIRRRA
EEEEECCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHCHHHHH
RVNELVEHYSVSRALRVIDMVDIVFLLVDVKEELTAQDKKIAHYATKRGKGIIIVFTKWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
LVDSKSGYFEALKSRVKFFFPVLSFSPILKISVHKKVGLDNLFKEAIKLKKQLELKMNTS
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHEEECHH
DLNKMLSLWIKDYHLNASHKVKYMTQISVNPVKFILFANKITNFPNSYYNYLVNNIRKIG
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHCC
YYNIPILIELREKTRDLK
EECCCEEEEEEHHCCCCC
>Mature Secondary Structure
MINSKVQNYKSVLIAGRPNVGKSTLFNKLLSSNRSITDEVYGVTRDLVKEVCTVDSYKFY
CCCCHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
LIDAGGFTLLRDELSRIVVNKVISLLDSIDLILLVLDVNEMLLEDYELIEKLRKYSDKIV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LVLNKIDSNHKEVLTYEFQKLGFKKSFLVSATHGKGINSLRIFLKNSVGKLASEDNTDVK
EEEECCCCCCHHHHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEE
IGIIGKPNSGKSTLINFLAGDEVSIVSPIAGTTRDFIKARFQRNGKIFELIDTAGIRRRA
EEEEECCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHCHHHHH
RVNELVEHYSVSRALRVIDMVDIVFLLVDVKEELTAQDKKIAHYATKRGKGIIIVFTKWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
LVDSKSGYFEALKSRVKFFFPVLSFSPILKISVHKKVGLDNLFKEAIKLKKQLELKMNTS
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHEEECHH
DLNKMLSLWIKDYHLNASHKVKYMTQISVNPVKFILFANKITNFPNSYYNYLVNNIRKIG
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHCC
YYNIPILIELREKTRDLK
EECCCEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA