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The map label for this gene is pcs [H]

Identifier: 187918122

GI number: 187918122

Start: 256845

End: 257549

Strand: Direct

Name: pcs [H]

Synonym: BH0249

Alternate gene names: 187918122

Gene position: 256845-257549 (Clockwise)

Preceding gene: 187918121

Following gene: 187918123

Centisome position: 27.85

GC content: 27.8

Gene sequence:

>705_bases
TTGGGGAAATTAAATCTTATTTTAGCCTGGTCAGTGCATATTTTAACAGCTTCCGGACTAATAATTGGTCTTTACTCAAT
AATCTCCATAATGAACACAGATTATAATCTCTTATTAAAGCTCACAATCCTTGGACTTTTAATTGATGGAATTGATGGCA
CACTGGCAAGAAAATTAAAGATAAAAGAAGTAATACCAACAATAAATGGAGAACTCCTTGATAATATTGTAGACTATATA
AACTATACATTTATTCCCACAATATTTTTTTATTGTGGGAATTTCATAAAAGATGAATATAAAACAATAACTTGTATTGG
AATTTTATTGGCATCAGCATATCAATTTTCAAGATTAGATGCAAAAACTAGTGATGATTACTTTAGAGGTTTTCCATCTT
TATGGAATTTTCTAATAATCTTTAACATAATATTTAAATTAAACCAAACCACAAATCTTAGCATAATATTATTATGTATC
GCATTCAGTTTTGCACCAATTAAATTCATCTATCCTTCAAAAACAAAAGAACTTAAATATATAACACTTCCTGCAACAGT
AATAACCGCCCTATCAGTAATACTTATAACATTTGCAAGACTGCCAGAGACCTATTTAAAGATAGGCAAAACACTAATAA
TTCTTTACTGTTTATACCTAATTCTAATGAGCACATATTTAACTTACAAGACAAGAAAAAAATAA

Upstream 100 bases:

>100_bases
GTGTCGACTTAAGTTTAAAATCAACAATAAAAAATACAATTAACATCTTTAAAGAACGTCTTGAGGATGTAAAAAAACTA
TTTTAATAAAGGAGTAAACC

Downstream 100 bases:

>100_bases
CGAGGCATTATGCATATCATACTAGAATTTATAGATCTCAATATAAACTATTCGCCAATTGTATTTTTTGGACTACTTAT
CCTTGCAGGTTTTAACATTC

Product: phosphatidylcholine synthase

Products: NA

Alternate protein names: PC synthase; CDP-diglyceride-choline O-phosphatidyltransferase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MGKLNLILAWSVHILTASGLIIGLYSIISIMNTDYNLLLKLTILGLLIDGIDGTLARKLKIKEVIPTINGELLDNIVDYI
NYTFIPTIFFYCGNFIKDEYKTITCIGILLASAYQFSRLDAKTSDDYFRGFPSLWNFLIIFNIIFKLNQTTNLSIILLCI
AFSFAPIKFIYPSKTKELKYITLPATVITALSVILITFARLPETYLKIGKTLIILYCLYLILMSTYLTYKTRKK

Sequences:

>Translated_234_residues
MGKLNLILAWSVHILTASGLIIGLYSIISIMNTDYNLLLKLTILGLLIDGIDGTLARKLKIKEVIPTINGELLDNIVDYI
NYTFIPTIFFYCGNFIKDEYKTITCIGILLASAYQFSRLDAKTSDDYFRGFPSLWNFLIIFNIIFKLNQTTNLSIILLCI
AFSFAPIKFIYPSKTKELKYITLPATVITALSVILITFARLPETYLKIGKTLIILYCLYLILMSTYLTYKTRKK
>Mature_233_residues
GKLNLILAWSVHILTASGLIIGLYSIISIMNTDYNLLLKLTILGLLIDGIDGTLARKLKIKEVIPTINGELLDNIVDYIN
YTFIPTIFFYCGNFIKDEYKTITCIGILLASAYQFSRLDAKTSDDYFRGFPSLWNFLIIFNIIFKLNQTTNLSIILLCIA
FSFAPIKFIYPSKTKELKYITLPATVITALSVILITFARLPETYLKIGKTLIILYCLYLILMSTYLTYKTRKK

Specific function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP [H]

COG id: COG1183

COG function: function code I; Phosphatidylserine synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.24 [H]

Molecular weight: Translated: 26664; Mature: 26533

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLNLILAWSVHILTASGLIIGLYSIISIMNTDYNLLLKLTILGLLIDGIDGTLARKLK
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
IKEVIPTINGELLDNIVDYINYTFIPTIFFYCGNFIKDEYKTITCIGILLASAYQFSRLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AKTSDDYFRGFPSLWNFLIIFNIIFKLNQTTNLSIILLCIAFSFAPIKFIYPSKTKELKY
CCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEE
ITLPATVITALSVILITFARLPETYLKIGKTLIILYCLYLILMSTYLTYKTRKK
EEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKLNLILAWSVHILTASGLIIGLYSIISIMNTDYNLLLKLTILGLLIDGIDGTLARKLK
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
IKEVIPTINGELLDNIVDYINYTFIPTIFFYCGNFIKDEYKTITCIGILLASAYQFSRLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AKTSDDYFRGFPSLWNFLIIFNIIFKLNQTTNLSIILLCIAFSFAPIKFIYPSKTKELKY
CCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEE
ITLPATVITALSVILITFARLPETYLKIGKTLIILYCLYLILMSTYLTYKTRKK
EEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]