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The map label for this gene is aroE [H]

Identifier: 187736453

GI number: 187736453

Start: 2393426

End: 2394358

Strand: Direct

Name: aroE [H]

Synonym: Amuc_1971

Alternate gene names: 187736453

Gene position: 2393426-2394358 (Clockwise)

Preceding gene: 187736452

Following gene: 187736454

Centisome position: 89.84

GC content: 60.24

Gene sequence:

>933_bases
ATGAAACCCTACTATACCCTGGCCGATCTTCTGGATGAAGAACATCCGTTTGACGCCGGGGAAACCGTTCCCGCCAGACT
GGTCGTAATCGGTTTCCCCATTGCCCATTCCAAATCCCCCGCCATGCAGCAGGCCGCGCTGGATGCGGCGGGCATTCGCG
CCCGGTATATCCGCATCCAGGCCGCTCCGGAAGAATTCGGGGAGGTGGTGCGGCTCCTCAGGAAAAGGGGATTCACGGGG
GCCAACGTTACGGTTCCCCACAAGCAGGCGGCCTGTTCCCTGTGCAGTGACACAGACGCCCTTTCCCGCGCTACCGGCTC
CGTCAATACTCTTGTTTTCCAACAGGACGGTTCCGTCTCCGGATTCAATACGGACGGCCCGGGGTTCGCCCGCGCCATCC
GGGAGGAATTTTCCGTGGATTTGCGCGATTTGAAAGTGGCCCTTCTGGGCTCCTGCGGCGGGGCCGGGCTTGCCCTGGCC
TACACCTGCGCCATGCAGCGTTGCGAACGGCTGACGCTGGCCGGAAGATCGGAAGAAAAGCTTCAGGAGCTTAAAAACAG
GCTGAGTTCCTTTTTCATTGACGAACACAGGCTGGAAGGGGCCTCCGACCGCCTGGCGGCCCACCAGAACAATACGCCCC
GTTTCAATGCCGCCGTGGAGGAAGCGGACCTGATCGTCAACGCCACCTCCCTCGGCCTGAAGCCTACGGACCCTTCCCCC
GTCCCCCCTGCACTGCTTTCCGCCCACCATCTGGTTTATGATTTACAGACGCATGACGATGCCTTCCAGATGGAAGCCCG
CTTTCAGGGCGCCAGAGTTTCCAACGGCCTTTCCATGCTGGTTCACCAGGGGGCCCTTTCCTTTGAACGCTGGTTCGGCA
TCAAGCCGGATATTTCCGCCATGCGCCAGGCTCTTGAACAAAAGCATGACTGA

Upstream 100 bases:

>100_bases
CGCCGCGCGGGGAAAAGGAATGATAGGCGTTTGCCTTGAAATCCGGCAGCATTTCATTCATAGTCCGGCGCGTACGCCTG
AAGCCGTTCCCACATTTTCC

Downstream 100 bases:

>100_bases
CGGCACCCCCCATTTTAACATCCATGCTTTCCGGAACGCGCTGGTAGAATGGTTCAGGCGCGAAGGGAGGGATTACCCGT
GGCGGCGGACAACGGATCCG

Product: Shikimate dehydrogenase substrate binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKPYYTLADLLDEEHPFDAGETVPARLVVIGFPIAHSKSPAMQQAALDAAGIRARYIRIQAAPEEFGEVVRLLRKRGFTG
ANVTVPHKQAACSLCSDTDALSRATGSVNTLVFQQDGSVSGFNTDGPGFARAIREEFSVDLRDLKVALLGSCGGAGLALA
YTCAMQRCERLTLAGRSEEKLQELKNRLSSFFIDEHRLEGASDRLAAHQNNTPRFNAAVEEADLIVNATSLGLKPTDPSP
VPPALLSAHHLVYDLQTHDDAFQMEARFQGARVSNGLSMLVHQGALSFERWFGIKPDISAMRQALEQKHD

Sequences:

>Translated_310_residues
MKPYYTLADLLDEEHPFDAGETVPARLVVIGFPIAHSKSPAMQQAALDAAGIRARYIRIQAAPEEFGEVVRLLRKRGFTG
ANVTVPHKQAACSLCSDTDALSRATGSVNTLVFQQDGSVSGFNTDGPGFARAIREEFSVDLRDLKVALLGSCGGAGLALA
YTCAMQRCERLTLAGRSEEKLQELKNRLSSFFIDEHRLEGASDRLAAHQNNTPRFNAAVEEADLIVNATSLGLKPTDPSP
VPPALLSAHHLVYDLQTHDDAFQMEARFQGARVSNGLSMLVHQGALSFERWFGIKPDISAMRQALEQKHD
>Mature_310_residues
MKPYYTLADLLDEEHPFDAGETVPARLVVIGFPIAHSKSPAMQQAALDAAGIRARYIRIQAAPEEFGEVVRLLRKRGFTG
ANVTVPHKQAACSLCSDTDALSRATGSVNTLVFQQDGSVSGFNTDGPGFARAIREEFSVDLRDLKVALLGSCGGAGLALA
YTCAMQRCERLTLAGRSEEKLQELKNRLSSFFIDEHRLEGASDRLAAHQNNTPRFNAAVEEADLIVNATSLGLKPTDPSP
VPPALLSAHHLVYDLQTHDDAFQMEARFQGARVSNGLSMLVHQGALSFERWFGIKPDISAMRQALEQKHD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=300, Percent_Identity=29, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789675, Length=284, Percent_Identity=30.9859154929577, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=292, Percent_Identity=23.6301369863014, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 33772; Mature: 33772

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPYYTLADLLDEEHPFDAGETVPARLVVIGFPIAHSKSPAMQQAALDAAGIRARYIRIQ
CCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEE
AAPEEFGEVVRLLRKRGFTGANVTVPHKQAACSLCSDTDALSRATGSVNTLVFQQDGSVS
ECHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCCCCC
GFNTDGPGFARAIREEFSVDLRDLKVALLGSCGGAGLALAYTCAMQRCERLTLAGRSEEK
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
LQELKNRLSSFFIDEHRLEGASDRLAAHQNNTPRFNAAVEEADLIVNATSLGLKPTDPSP
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHEEEEHHHCCCCCCCCCC
VPPALLSAHHLVYDLQTHDDAFQMEARFQGARVSNGLSMLVHQGALSFERWFGIKPDISA
CCHHHHHHHHHEEEECCCCCHHHHHHHHCCCHHHCHHHHHHHHCCHHHHHHCCCCCCHHH
MRQALEQKHD
HHHHHHHCCC
>Mature Secondary Structure
MKPYYTLADLLDEEHPFDAGETVPARLVVIGFPIAHSKSPAMQQAALDAAGIRARYIRIQ
CCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEE
AAPEEFGEVVRLLRKRGFTGANVTVPHKQAACSLCSDTDALSRATGSVNTLVFQQDGSVS
ECHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCCCCC
GFNTDGPGFARAIREEFSVDLRDLKVALLGSCGGAGLALAYTCAMQRCERLTLAGRSEEK
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
LQELKNRLSSFFIDEHRLEGASDRLAAHQNNTPRFNAAVEEADLIVNATSLGLKPTDPSP
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHEEEEHHHCCCCCCCCCC
VPPALLSAHHLVYDLQTHDDAFQMEARFQGARVSNGLSMLVHQGALSFERWFGIKPDISA
CCHHHHHHHHHEEEECCCCCHHHHHHHHCCCHHHCHHHHHHHHCCHHHHHHCCCCCCHHH
MRQALEQKHD
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA