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The map label for this gene is pabB [C]

Identifier: 187736431

GI number: 187736431

Start: 2367143

End: 2368159

Strand: Reverse

Name: pabB [C]

Synonym: Amuc_1949

Alternate gene names: 187736431

Gene position: 2368159-2367143 (Counterclockwise)

Preceding gene: 187736434

Following gene: 187736430

Centisome position: 88.89

GC content: 58.31

Gene sequence:

>1017_bases
ATGTACACACGGGAACAGACCATCAGCCGCATGAATGCCCTGGGCCGTGCGGAGTGTCCGTTCTTTTTTGTCATCTCCCA
TGATATGGGCCATAACCTGCTGTTTGAACCTTCGGAAACGGAGGGGGAGCGCATGGCTGCTTTTTCCCTGCCGCTGGGCA
CGATGGGAAATCAGGACGGCGGCCCTCCGCTTCCGGAACGGCTGCGGTTCATTCCATCCCCCCATCCCGTGTCCCGGTAT
GCGGCATCCTTCGCCTCCGTCCGGAACCATCTGATGAGGGGGGATTCCTACCTGCTGAATTTATGCGTGTCCACCCCCGT
GGAAACCAACCTGACGCTGCGCCATCTGTTCCGGTTTGCCCGCGCGCCTTACCGGATGCTGCTGGGGCCGGACGCGCGGA
TTTCCGGAGTGCACGGCCGCGGCTGCGTCTGCTTTTCTCCGGAACCGTTTGTCACGGTGCGCGGCCGCTCCATTTCCACG
TTTCCCATGAAGGGAACGGTTCCGTCCGCTACGCAGGAAGCGCGCCGCTGGCTGGAAACGGATGAAAAGGAGAATAGGGA
ATCCGCCACCATTGTGGATCTGATGCGCAATGATCTTTCCATGGTGGCAACCGGCGTGAGGGTGAAGCGTTACCGCTATA
TCAGCCCTGTAGAAACGTCCAAAGGGCCTATTCTTCAATGCAGTTCCGAGATTTCCGGGCTGTTGCCGGAAAACTGGCGT
TCCCGCCTGGGGGAAATCCTTCTGAAGCTGCTTCCTGCCGGGAGCGTGACCGGAGCGCCCAAGGAAGCCACCTGCCGGGC
CATCGCGGAAGCGGAGGATATGGAGAGGGGGTTTTATACCGGAATTTTCGGCTTTTTCAACGGGCGGGATTTGGATTCCG
CCGTCTCCATCCGCTTCATGGAGGAGGATGAACGGGGAATGGTATACAAGAGCGGTGGAGGAATTACCGTCATGAGCCGG
ATGGAAGAGGAATACCAGGAAGCTGTTGCCAAAGTTTATGTGCCGTTTGATTTTTGA

Upstream 100 bases:

>100_bases
TGACGAGTTCCGCAAGATTCCAGGTGAAGGAATCCCGGTGGTCGATGATCCAGACGTTCGGTTGACTCATGGCGCGCACA
TGATAGAGTAATTCCCGACA

Downstream 100 bases:

>100_bases
AACCGTTAAATGGGAGAATGGCGCTCCCTGTCTGCTTCCCTGGCACCAGCGGAGGATGGAGGCCGCCATCGGCGTTCATG
GTTCGGACGGAGCTTCCGTC

Product: para-aminobenzoate synthase component I

Products: 4-amino-4-deoxychorismate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MYTREQTISRMNALGRAECPFFFVISHDMGHNLLFEPSETEGERMAAFSLPLGTMGNQDGGPPLPERLRFIPSPHPVSRY
AASFASVRNHLMRGDSYLLNLCVSTPVETNLTLRHLFRFARAPYRMLLGPDARISGVHGRGCVCFSPEPFVTVRGRSIST
FPMKGTVPSATQEARRWLETDEKENRESATIVDLMRNDLSMVATGVRVKRYRYISPVETSKGPILQCSSEISGLLPENWR
SRLGEILLKLLPAGSVTGAPKEATCRAIAEAEDMERGFYTGIFGFFNGRDLDSAVSIRFMEEDERGMVYKSGGGITVMSR
MEEEYQEAVAKVYVPFDF

Sequences:

>Translated_338_residues
MYTREQTISRMNALGRAECPFFFVISHDMGHNLLFEPSETEGERMAAFSLPLGTMGNQDGGPPLPERLRFIPSPHPVSRY
AASFASVRNHLMRGDSYLLNLCVSTPVETNLTLRHLFRFARAPYRMLLGPDARISGVHGRGCVCFSPEPFVTVRGRSIST
FPMKGTVPSATQEARRWLETDEKENRESATIVDLMRNDLSMVATGVRVKRYRYISPVETSKGPILQCSSEISGLLPENWR
SRLGEILLKLLPAGSVTGAPKEATCRAIAEAEDMERGFYTGIFGFFNGRDLDSAVSIRFMEEDERGMVYKSGGGITVMSR
MEEEYQEAVAKVYVPFDF
>Mature_338_residues
MYTREQTISRMNALGRAECPFFFVISHDMGHNLLFEPSETEGERMAAFSLPLGTMGNQDGGPPLPERLRFIPSPHPVSRY
AASFASVRNHLMRGDSYLLNLCVSTPVETNLTLRHLFRFARAPYRMLLGPDARISGVHGRGCVCFSPEPFVTVRGRSIST
FPMKGTVPSATQEARRWLETDEKENRESATIVDLMRNDLSMVATGVRVKRYRYISPVETSKGPILQCSSEISGLLPENWR
SRLGEILLKLLPAGSVTGAPKEATCRAIAEAEDMERGFYTGIFGFFNGRDLDSAVSIRFMEEDERGMVYKSGGGITVMSR
MEEEYQEAVAKVYVPFDF

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To the C-terminal of para-aminobenzoate synthase component I [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=268, Percent_Identity=29.4776119402985, Blast_Score=96, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324361, Length=299, Percent_Identity=28.7625418060201, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320935, Length=339, Percent_Identity=26.2536873156342, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: 6.3.5.8

Molecular weight: Translated: 37821; Mature: 37821

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTREQTISRMNALGRAECPFFFVISHDMGHNLLFEPSETEGERMAAFSLPLGTMGNQDG
CCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCC
GPPLPERLRFIPSPHPVSRYAASFASVRNHLMRGDSYLLNLCVSTPVETNLTLRHLFRFA
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCCCCHHHHHHHHHH
RAPYRMLLGPDARISGVHGRGCVCFSPEPFVTVRGRSISTFPMKGTVPSATQEARRWLET
CCCCEEEECCCCCEECCCCCEEEEECCCCEEEECCCEEEECCCCCCCCCHHHHHHHHHCC
DEKENRESATIVDLMRNDLSMVATGVRVKRYRYISPVETSKGPILQCSSEISGLLPENWR
CCCCCCHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCEEEECHHHCCCCCHHHH
SRLGEILLKLLPAGSVTGAPKEATCRAIAEAEDMERGFYTGIFGFFNGRDLDSAVSIRFM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEEEEE
EEDERGMVYKSGGGITVMSRMEEEYQEAVAKVYVPFDF
ECCCCCEEEECCCCEEHHHHHHHHHHHHHHEEECCCCC
>Mature Secondary Structure
MYTREQTISRMNALGRAECPFFFVISHDMGHNLLFEPSETEGERMAAFSLPLGTMGNQDG
CCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCC
GPPLPERLRFIPSPHPVSRYAASFASVRNHLMRGDSYLLNLCVSTPVETNLTLRHLFRFA
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCCCCHHHHHHHHHH
RAPYRMLLGPDARISGVHGRGCVCFSPEPFVTVRGRSISTFPMKGTVPSATQEARRWLET
CCCCEEEECCCCCEECCCCCEEEEECCCCEEEECCCEEEECCCCCCCCCHHHHHHHHHCC
DEKENRESATIVDLMRNDLSMVATGVRVKRYRYISPVETSKGPILQCSSEISGLLPENWR
CCCCCCHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCEEEECHHHCCCCCHHHH
SRLGEILLKLLPAGSVTGAPKEATCRAIAEAEDMERGFYTGIFGFFNGRDLDSAVSIRFM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEEEEE
EEDERGMVYKSGGGITVMSRMEEEYQEAVAKVYVPFDF
ECCCCCEEEECCCCEEHHHHHHHHHHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chorismate; L-glutamine

Specific reaction: chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

General reaction: Lyases; Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]