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The map label for this gene is nahA [H]

Identifier: 187736406

GI number: 187736406

Start: 2334650

End: 2336644

Strand: Direct

Name: nahA [H]

Synonym: Amuc_1924

Alternate gene names: 187736406

Gene position: 2334650-2336644 (Clockwise)

Preceding gene: 187736405

Following gene: 187736420

Centisome position: 87.63

GC content: 55.59

Gene sequence:

>1995_bases
ATGCGATTATCCCTTTCCGCGCCTTTGCTGGCTTCCGGCCTGATGCTTTGTTTTACCTCCTCCCATGGAGACTGGACATC
CCCGCACCCTCTCCAGCAGGAAAAAGCCGCTCCGGTCCCACTGATTCCCTTCCCGTCCCAGGTGGACTGGAAAACGGGAA
CATGCCCTAAAAAGGCTCCCGTTTCCGTGAAAAAAAACGCGTCCCTGTCTAAGACGCTGGGCAAGGAAGGGTATGAACTG
CGGATCCGCCCCAACGGCATTCTGATTAAGGCCGCTGACGATGCGGGCGTTTTTTATGCCCGCAGAACGCTGGACCAGCT
GGGAGCCAGGGGAGATTACCCGTGCTGCGACATCAAGGACAGCCCCGCGTTCGCCATCCGGTGCTTCATGCATGACGCAG
GCCGCCATTTCCGGACTGTTGAAACACTCAAGGCGGATATTGATGAAATGGCCCGGCTGAAAATAAACGCTTTTCACTGG
CATCTGACGGATTACCCCGCATGGCGCATCCAGTGCAAAAAGTACCCTGTTTTGAATGATCCCTCCAAGAGGATTCAGGG
ACGGGACGTTAACGGCACCTACTCCTACGACCAGATACGGGACTTATTCCGCTACGCCAGGGAGCGCCATGTCCAGATTA
TTCCGGAAATCGATATGCCCGGGCACAGCACCTATTTTAAAAACTGCTTTGGCTTCCCGATGCATGATCCCAGAGGCATC
AACATTCTGGAAGAACTGCTGGAAGAATTTTGCAGGGAAATTCCGGCGGAAATGTCTCCCTACCTTCATATCGGAGCGGA
TGAAATCCGCATTCCCAACGGAAAGCAGTTTGCGGACCGGATGGCGGCCAAGGTCAAATCCCTGGGACGGCAGCCCATCC
AATGGGCGGGCAACAATGACCTGCCTGTGTCCGGAGACAGTTATGCCCAGCTGTGGAATGATGAAAATTCCGTAGGCCTG
CCGGATCCAGCCAGGCAGAAGAATCCCTACTTCGACTCCACGGCAGGATACGTCAATTCCTTTGACCCCGGCATTCTGGT
GCGCAGGAATTTCTTCCGCCAGCCCTGCGGAACAGCCAGGGGAAACAACCATTCCCTGGGCGTCATCCAGTGTCTATGGC
CGGATACCCGGGTGGAGAACAAAAAAAACATTCCTGTCCAGAGCCCCCAGTGGCCTGCCATGTTCGCCATGGCGGAACGC
AGTTGGAAAGGAATTCCAGAGGATGGTTCCCGTTTTGCCGGCAGTCTGCCGGAAAAGAACACGGAGGCTTATCAGGCCTT
CTCTCTGTTTGAAAAACGCATGGAAGCCCTGGCCGGAAGCAGGCCTTTCCCTTACTGGAGGGATTCTTTCGTGGAATGGA
CGGTATTCGGCCCCGTTCCGCAGGACAGGCAGGAAGAAGTAAGAAATAACCTGCTGGCGGGCAAATCTCCCGCAGGACTG
TCTTCCGTCCAGACGCGAGGAGGCAATTTGTATTTCCGTACCCGTGCGGGTGCGGAGGGTCTATTTTCCAAGACAAAACC
GGGGAATACGGTCTGGGCGGAGACGACGTTTCACGCGCCCGTGGAGGGCACCATGCACGCTATGGTGGGGTTTGACGCTC
CGGCCCGTTCCACACGGCGCTGTTCCGGAGTACCGGCTGCCGGGGAGTGGTCCCAGTGCGGCACCAGAATATGGGTAAAC
GGCAAGGAAATGAAAAATCCCCAGACTTACAAACTGGCAGGCCAACGGCGTTACGAAAAGCATACATGGAATTCGCCCGC
TAATGAGATACCCTTTGACAACGAGGAATTCTGGTGGGCCCGGCCTCCTGTTCCCTTTCAAGTGAAGGCCGGGGAAAACA
GGATCCTGATAGAACAACCGTACACAGGAGAATTCCAGTCGTGGGGAGTCAGCTTCATTCCGGTGAAAAAAGCGGGAGAC
CGCTGGATTGCCGACCCAAGCTATTATGCCAAACCCAGGAGAGAGAAACAGGATGACGTCTCTCCGGTGCCATAA

Upstream 100 bases:

>100_bases
CGCATAAGGATAGGATAATTTTATACTGCGTAAAATGTTTTCTTTTGCAATTTCCCTGTTTCTTTGAAAGATCATTCATC
ATCCACGTGTAATATTTGCC

Downstream 100 bases:

>100_bases
AAGTAAACATGGAACACTCCCGGCGGAGCTTTCCGTCCGTTGTTCCAAAGGTCATTTTCCCCCGCTCATCAGGACGAGGG
AACGGGGGAAATAGCGTTTG

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MRLSLSAPLLASGLMLCFTSSHGDWTSPHPLQQEKAAPVPLIPFPSQVDWKTGTCPKKAPVSVKKNASLSKTLGKEGYEL
RIRPNGILIKAADDAGVFYARRTLDQLGARGDYPCCDIKDSPAFAIRCFMHDAGRHFRTVETLKADIDEMARLKINAFHW
HLTDYPAWRIQCKKYPVLNDPSKRIQGRDVNGTYSYDQIRDLFRYARERHVQIIPEIDMPGHSTYFKNCFGFPMHDPRGI
NILEELLEEFCREIPAEMSPYLHIGADEIRIPNGKQFADRMAAKVKSLGRQPIQWAGNNDLPVSGDSYAQLWNDENSVGL
PDPARQKNPYFDSTAGYVNSFDPGILVRRNFFRQPCGTARGNNHSLGVIQCLWPDTRVENKKNIPVQSPQWPAMFAMAER
SWKGIPEDGSRFAGSLPEKNTEAYQAFSLFEKRMEALAGSRPFPYWRDSFVEWTVFGPVPQDRQEEVRNNLLAGKSPAGL
SSVQTRGGNLYFRTRAGAEGLFSKTKPGNTVWAETTFHAPVEGTMHAMVGFDAPARSTRRCSGVPAAGEWSQCGTRIWVN
GKEMKNPQTYKLAGQRRYEKHTWNSPANEIPFDNEEFWWARPPVPFQVKAGENRILIEQPYTGEFQSWGVSFIPVKKAGD
RWIADPSYYAKPRREKQDDVSPVP

Sequences:

>Translated_664_residues
MRLSLSAPLLASGLMLCFTSSHGDWTSPHPLQQEKAAPVPLIPFPSQVDWKTGTCPKKAPVSVKKNASLSKTLGKEGYEL
RIRPNGILIKAADDAGVFYARRTLDQLGARGDYPCCDIKDSPAFAIRCFMHDAGRHFRTVETLKADIDEMARLKINAFHW
HLTDYPAWRIQCKKYPVLNDPSKRIQGRDVNGTYSYDQIRDLFRYARERHVQIIPEIDMPGHSTYFKNCFGFPMHDPRGI
NILEELLEEFCREIPAEMSPYLHIGADEIRIPNGKQFADRMAAKVKSLGRQPIQWAGNNDLPVSGDSYAQLWNDENSVGL
PDPARQKNPYFDSTAGYVNSFDPGILVRRNFFRQPCGTARGNNHSLGVIQCLWPDTRVENKKNIPVQSPQWPAMFAMAER
SWKGIPEDGSRFAGSLPEKNTEAYQAFSLFEKRMEALAGSRPFPYWRDSFVEWTVFGPVPQDRQEEVRNNLLAGKSPAGL
SSVQTRGGNLYFRTRAGAEGLFSKTKPGNTVWAETTFHAPVEGTMHAMVGFDAPARSTRRCSGVPAAGEWSQCGTRIWVN
GKEMKNPQTYKLAGQRRYEKHTWNSPANEIPFDNEEFWWARPPVPFQVKAGENRILIEQPYTGEFQSWGVSFIPVKKAGD
RWIADPSYYAKPRREKQDDVSPVP
>Mature_664_residues
MRLSLSAPLLASGLMLCFTSSHGDWTSPHPLQQEKAAPVPLIPFPSQVDWKTGTCPKKAPVSVKKNASLSKTLGKEGYEL
RIRPNGILIKAADDAGVFYARRTLDQLGARGDYPCCDIKDSPAFAIRCFMHDAGRHFRTVETLKADIDEMARLKINAFHW
HLTDYPAWRIQCKKYPVLNDPSKRIQGRDVNGTYSYDQIRDLFRYARERHVQIIPEIDMPGHSTYFKNCFGFPMHDPRGI
NILEELLEEFCREIPAEMSPYLHIGADEIRIPNGKQFADRMAAKVKSLGRQPIQWAGNNDLPVSGDSYAQLWNDENSVGL
PDPARQKNPYFDSTAGYVNSFDPGILVRRNFFRQPCGTARGNNHSLGVIQCLWPDTRVENKKNIPVQSPQWPAMFAMAER
SWKGIPEDGSRFAGSLPEKNTEAYQAFSLFEKRMEALAGSRPFPYWRDSFVEWTVFGPVPQDRQEEVRNNLLAGKSPAGL
SSVQTRGGNLYFRTRAGAEGLFSKTKPGNTVWAETTFHAPVEGTMHAMVGFDAPARSTRRCSGVPAAGEWSQCGTRIWVN
GKEMKNPQTYKLAGQRRYEKHTWNSPANEIPFDNEEFWWARPPVPFQVKAGENRILIEQPYTGEFQSWGVSFIPVKKAGD
RWIADPSYYAKPRREKQDDVSPVP

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=392, Percent_Identity=23.7244897959184, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI4504373, Length=218, Percent_Identity=26.605504587156, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17569815, Length=437, Percent_Identity=24.4851258581236, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24653074, Length=178, Percent_Identity=32.5842696629214, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45551090, Length=178, Percent_Identity=32.5842696629214, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24657468, Length=206, Percent_Identity=25.7281553398058, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17647501, Length=206, Percent_Identity=25.7281553398058, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281365639, Length=206, Percent_Identity=25.7281553398058, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24657474, Length=206, Percent_Identity=25.7281553398058, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17933586, Length=254, Percent_Identity=25.9842519685039, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 75141; Mature: 75141

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSLSAPLLASGLMLCFTSSHGDWTSPHPLQQEKAAPVPLIPFPSQVDWKTGTCPKKAP
CEECCCCCHHHCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
VSVKKNASLSKTLGKEGYELRIRPNGILIKAADDAGVFYARRTLDQLGARGDYPCCDIKD
CCCCCCCCHHHHHCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
SPAFAIRCFMHDAGRHFRTVETLKADIDEMARLKINAFHWHLTDYPAWRIQCKKYPVLND
CCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEECCCCCCC
PSKRIQGRDVNGTYSYDQIRDLFRYARERHVQIIPEIDMPGHSTYFKNCFGFPMHDPRGI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCC
NILEELLEEFCREIPAEMSPYLHIGADEIRIPNGKQFADRMAAKVKSLGRQPIQWAGNND
HHHHHHHHHHHHHCCHHCCCEEEECCCCEECCCCHHHHHHHHHHHHHHCCCCEEECCCCC
LPVSGDSYAQLWNDENSVGLPDPARQKNPYFDSTAGYVNSFDPGILVRRNFFRQPCGTAR
CCCCCCHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCCCC
GNNHSLGVIQCLWPDTRVENKKNIPVQSPQWPAMFAMAERSWKGIPEDGSRFAGSLPEKN
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCC
TEAYQAFSLFEKRMEALAGSRPFPYWRDSFVEWTVFGPVPQDRQEEVRNNLLAGKSPAGL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
SSVQTRGGNLYFRTRAGAEGLFSKTKPGNTVWAETTFHAPVEGTMHAMVGFDAPARSTRR
HHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHH
CSGVPAAGEWSQCGTRIWVNGKEMKNPQTYKLAGQRRYEKHTWNSPANEIPFDNEEFWWA
CCCCCCCCCHHHCCCEEEECCHHCCCCCEEEECCHHHHHHHCCCCCCCCCCCCCCCCEEE
RPPVPFQVKAGENRILIEQPYTGEFQSWGVSFIPVKKAGDRWIADPSYYAKPRREKQDDV
CCCCCEEEECCCCEEEEECCCCCCHHHCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCC
SPVP
CCCC
>Mature Secondary Structure
MRLSLSAPLLASGLMLCFTSSHGDWTSPHPLQQEKAAPVPLIPFPSQVDWKTGTCPKKAP
CEECCCCCHHHCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
VSVKKNASLSKTLGKEGYELRIRPNGILIKAADDAGVFYARRTLDQLGARGDYPCCDIKD
CCCCCCCCHHHHHCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
SPAFAIRCFMHDAGRHFRTVETLKADIDEMARLKINAFHWHLTDYPAWRIQCKKYPVLND
CCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEECCCCCCC
PSKRIQGRDVNGTYSYDQIRDLFRYARERHVQIIPEIDMPGHSTYFKNCFGFPMHDPRGI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCC
NILEELLEEFCREIPAEMSPYLHIGADEIRIPNGKQFADRMAAKVKSLGRQPIQWAGNND
HHHHHHHHHHHHHCCHHCCCEEEECCCCEECCCCHHHHHHHHHHHHHHCCCCEEECCCCC
LPVSGDSYAQLWNDENSVGLPDPARQKNPYFDSTAGYVNSFDPGILVRRNFFRQPCGTAR
CCCCCCHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCCCC
GNNHSLGVIQCLWPDTRVENKKNIPVQSPQWPAMFAMAERSWKGIPEDGSRFAGSLPEKN
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCC
TEAYQAFSLFEKRMEALAGSRPFPYWRDSFVEWTVFGPVPQDRQEEVRNNLLAGKSPAGL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
SSVQTRGGNLYFRTRAGAEGLFSKTKPGNTVWAETTFHAPVEGTMHAMVGFDAPARSTRR
HHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHH
CSGVPAAGEWSQCGTRIWVNGKEMKNPQTYKLAGQRRYEKHTWNSPANEIPFDNEEFWWA
CCCCCCCCCHHHCCCEEEECCHHCCCCCEEEECCHHHHHHHCCCCCCCCCCCCCCCCEEE
RPPVPFQVKAGENRILIEQPYTGEFQSWGVSFIPVKKAGDRWIADPSYYAKPRREKQDDV
CCCCCEEEECCCCEEEEECCCCCCHHHCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCC
SPVP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]