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The map label for this gene is yggB [C]

Identifier: 187736370

GI number: 187736370

Start: 2291282

End: 2293717

Strand: Reverse

Name: yggB [C]

Synonym: Amuc_1887

Alternate gene names: 187736370

Gene position: 2293717-2291282 (Counterclockwise)

Preceding gene: 187736371

Following gene: 187736369

Centisome position: 86.1

GC content: 54.52

Gene sequence:

>2436_bases
ATGAGCATCCCTGATTACCGGATCTTTTTCCGCCGCTGCGCCGCCTTTTTCCTGGCGGGGGTTCTGGCCGCAGGTTCTGC
ATCTGCACAGCAGGAGGCTCCGCCTGCCGCCGCCCCGGAACAGGCGGAGGAAGCCAAGGCGGAACAGCCTCAGGAGCAGC
CGGACCAATCGGAAATGGATACCGTAATCATGGCTCTGTGCCATGAAATCACCATTCTGAAAAAGAATGAGGAAAAAAGG
ATGGCCATCCGGAAAACGCTGGTGAGGGAAGCGGATGCTACCTATAATTATTTTGATACTAGGGTGTATGAAATGTCCGC
CGTGCTTTACGCGCTGGACGACCAAAAAATATTTACGCTGGCTTTTTACTGTAAGGCCGCTTCCAGCCTGGTGAAGACGT
ATTACGCCCAAAAACCGGATTTTCAGGGGCAGGAGGAACGGCTGGACAAGGAAATAGAACGCATTAAAAAGCTGGCGGCA
TCCCTGGAGGAAGTAAATACGGACACCCTGTCGCAAGCCTCCCTGGTTCAGCGGGACGAAGCCCTGTATGCCTGCCAGGA
GCTGGAAGAATCCCTCCAAAGTGAAAAGGAGCAAATCAGCTACCTCAAGGAACTTTTCAGCAGCCTGAACGGCAAAATAG
ACGCGCTCAACAATGAAAGCGCCAAACTGTTCACCGCCCTGTTTAACAGGGTCTTCTACACGCCGTCCCACGCGGCCCGG
TACATCTTTCTCAAACCGCACAAGACGTATGAAACGTGCATGGGGGCATGGGAAACATCCGCGGACAGCAAGCTCCAGCT
TCCGTCAGACCCGGAAACGCTCAAGCATTACGGACTTATCCTGCTGGGAATCATCCTGTGCTCCTACTGCCTCTCCCGCA
TCATCATCTTCCTGGGATTCCGAAATACATTGAAAAAGACGGGGCATTACAACAAACGCCATGCTTTCGCCAACGTCACC
ACCATTCTTATCGTGGCGCTGATCCTCGTCATTGCCTCACTGCGCACGCCGAACTACCTGCTGGAGAGCGCGGCCTCCCT
GGGCGCGGAATTCCTTCTTCTGGTCAGCGCCATCCTGTTCTCCCTGGTCACGCGCCTTCCGTATGGCACCATTAACTCCG
GCATCCGCATCTACATGCCCTATCTGCTTCTGGGCGGATTCTTCATGCTTCTGCGCATGTTCATGGCCCCCAACATCATC
GTGGACATTTCCATGCCCATCCTGTTCACGCTGGTTTCCCTCTTCTCCCTGCTGACCTGGGTGCGGCAGAGGCACAAGCT
GCCCCGGCTGGACCGTTTTTTCTCCACCGTATCTCTGGTATTCACCATCCTGGGCAGCGTCCTGTGCTGGACTGGATTCA
GCTTCATGGCCTTCCTGGTGCTGATGACCTGGATCATGCTGATGACCAGCATCCTTCTGCTGGTGGGGCTGTGGGATCTG
CTCCACCATTATGAAAACCGCCGGAAGGAACGGAACAAGAGGGCCATCCTGTGGTTCCGCCCCTTCATCTCCAAGCTGCT
GCTTCCCTGCCTGACCATTTTCCTCATCCTGTTCAGCATCATCTGGCCCGCCGCCACCTTCGACATGGGGGACCTCATCA
TTAATAAAATTTTCGCAACCACGGAAATCAAGGATCTGCTCACTTTCAGCTGGAGCAGCGTCATCACGGTCATCCTGATG
GCCATTGTTCTCAACTACTTGATATTCTTGGGGAAAAATACGCTGCATGAAATCTATGGAGAAGATTATGAAGTAGGCAC
CATCCCCACCTTCGTGACACTCTCCACCCTTTTTCTCTGGGGGCTCTTCGTTTTTACGGCGCTTATCATCATGAACGCCA
ACTACAACGGGCTGCTGATGGTCATGGGAGGCTTGAGCATGGGCATCGGCTTCGCCCTGAAAGATACCATTGAAAACATC
ATCAGCGGCCTCTCCCTAATGCTGGGTCGCCTGCGCCAGGGCGACATGATTGAATGCGACGGCTACCGGGGCCGCGTCTC
CTCCCTGGGCTACCGCTCCACCATGATCGAGACGCTGGACGGCTCTATCATCGCCTTCCAGAACTCCCAGCTTTTCAACA
AGAACTTCCGCAACATGACCCGCAACCACAAATTCGAATGCGTGAAGGTGGAAGTGGGCATTTCCTACGGGACGGACGTG
GAAAGGGCGCGCAAAATCATTCTGGAAACGCTGGCAACCCTGCCCTTCCTTTCCAAAGTCAAGAAAACCAGCGTGGTGCT
GGACAGTTTCGGAGACAGTGCCGTCAATCTGGGCGTATGGGTCTGGGTTCCCGTCATGACAAAGTCCTCCAGCCTTTCCT
CCGTGCGGGAACACATCTATAATGCGTTCAACGAACACGGCATTTCCATCCCATTCCCTCAACAGGACTTGTACGTGAAA
GAATTCCTCGGCGGAGCCCCCGTCCAGGGGACCTGA

Upstream 100 bases:

>100_bases
ACGTTGAAAAAAGTTTTTTTCTGTGAAGCTCACCCTCCGTCAGCAGGAGAATATATAACCTTGACCGTAATGCCTGCAGC
CCCTAGAACAGGGACCATTC

Downstream 100 bases:

>100_bases
ACATCCATTACCATATACAACAACCATGTCCGACGACCATCTGACTCTATTAGGCTCTCAAAGCTCCTTCTTTACCAATC
CCGACGACGCCAGGCTGGAA

Product: MscS Mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MSIPDYRIFFRRCAAFFLAGVLAAGSASAQQEAPPAAAPEQAEEAKAEQPQEQPDQSEMDTVIMALCHEITILKKNEEKR
MAIRKTLVREADATYNYFDTRVYEMSAVLYALDDQKIFTLAFYCKAASSLVKTYYAQKPDFQGQEERLDKEIERIKKLAA
SLEEVNTDTLSQASLVQRDEALYACQELEESLQSEKEQISYLKELFSSLNGKIDALNNESAKLFTALFNRVFYTPSHAAR
YIFLKPHKTYETCMGAWETSADSKLQLPSDPETLKHYGLILLGIILCSYCLSRIIIFLGFRNTLKKTGHYNKRHAFANVT
TILIVALILVIASLRTPNYLLESAASLGAEFLLLVSAILFSLVTRLPYGTINSGIRIYMPYLLLGGFFMLLRMFMAPNII
VDISMPILFTLVSLFSLLTWVRQRHKLPRLDRFFSTVSLVFTILGSVLCWTGFSFMAFLVLMTWIMLMTSILLLVGLWDL
LHHYENRRKERNKRAILWFRPFISKLLLPCLTIFLILFSIIWPAATFDMGDLIINKIFATTEIKDLLTFSWSSVITVILM
AIVLNYLIFLGKNTLHEIYGEDYEVGTIPTFVTLSTLFLWGLFVFTALIIMNANYNGLLMVMGGLSMGIGFALKDTIENI
ISGLSLMLGRLRQGDMIECDGYRGRVSSLGYRSTMIETLDGSIIAFQNSQLFNKNFRNMTRNHKFECVKVEVGISYGTDV
ERARKIILETLATLPFLSKVKKTSVVLDSFGDSAVNLGVWVWVPVMTKSSSLSSVREHIYNAFNEHGISIPFPQQDLYVK
EFLGGAPVQGT

Sequences:

>Translated_811_residues
MSIPDYRIFFRRCAAFFLAGVLAAGSASAQQEAPPAAAPEQAEEAKAEQPQEQPDQSEMDTVIMALCHEITILKKNEEKR
MAIRKTLVREADATYNYFDTRVYEMSAVLYALDDQKIFTLAFYCKAASSLVKTYYAQKPDFQGQEERLDKEIERIKKLAA
SLEEVNTDTLSQASLVQRDEALYACQELEESLQSEKEQISYLKELFSSLNGKIDALNNESAKLFTALFNRVFYTPSHAAR
YIFLKPHKTYETCMGAWETSADSKLQLPSDPETLKHYGLILLGIILCSYCLSRIIIFLGFRNTLKKTGHYNKRHAFANVT
TILIVALILVIASLRTPNYLLESAASLGAEFLLLVSAILFSLVTRLPYGTINSGIRIYMPYLLLGGFFMLLRMFMAPNII
VDISMPILFTLVSLFSLLTWVRQRHKLPRLDRFFSTVSLVFTILGSVLCWTGFSFMAFLVLMTWIMLMTSILLLVGLWDL
LHHYENRRKERNKRAILWFRPFISKLLLPCLTIFLILFSIIWPAATFDMGDLIINKIFATTEIKDLLTFSWSSVITVILM
AIVLNYLIFLGKNTLHEIYGEDYEVGTIPTFVTLSTLFLWGLFVFTALIIMNANYNGLLMVMGGLSMGIGFALKDTIENI
ISGLSLMLGRLRQGDMIECDGYRGRVSSLGYRSTMIETLDGSIIAFQNSQLFNKNFRNMTRNHKFECVKVEVGISYGTDV
ERARKIILETLATLPFLSKVKKTSVVLDSFGDSAVNLGVWVWVPVMTKSSSLSSVREHIYNAFNEHGISIPFPQQDLYVK
EFLGGAPVQGT
>Mature_810_residues
SIPDYRIFFRRCAAFFLAGVLAAGSASAQQEAPPAAAPEQAEEAKAEQPQEQPDQSEMDTVIMALCHEITILKKNEEKRM
AIRKTLVREADATYNYFDTRVYEMSAVLYALDDQKIFTLAFYCKAASSLVKTYYAQKPDFQGQEERLDKEIERIKKLAAS
LEEVNTDTLSQASLVQRDEALYACQELEESLQSEKEQISYLKELFSSLNGKIDALNNESAKLFTALFNRVFYTPSHAARY
IFLKPHKTYETCMGAWETSADSKLQLPSDPETLKHYGLILLGIILCSYCLSRIIIFLGFRNTLKKTGHYNKRHAFANVTT
ILIVALILVIASLRTPNYLLESAASLGAEFLLLVSAILFSLVTRLPYGTINSGIRIYMPYLLLGGFFMLLRMFMAPNIIV
DISMPILFTLVSLFSLLTWVRQRHKLPRLDRFFSTVSLVFTILGSVLCWTGFSFMAFLVLMTWIMLMTSILLLVGLWDLL
HHYENRRKERNKRAILWFRPFISKLLLPCLTIFLILFSIIWPAATFDMGDLIINKIFATTEIKDLLTFSWSSVITVILMA
IVLNYLIFLGKNTLHEIYGEDYEVGTIPTFVTLSTLFLWGLFVFTALIIMNANYNGLLMVMGGLSMGIGFALKDTIENII
SGLSLMLGRLRQGDMIECDGYRGRVSSLGYRSTMIETLDGSIIAFQNSQLFNKNFRNMTRNHKFECVKVEVGISYGTDVE
RARKIILETLATLPFLSKVKKTSVVLDSFGDSAVNLGVWVWVPVMTKSSSLSSVREHIYNAFNEHGISIPFPQQDLYVKE
FLGGAPVQGT

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=225, Percent_Identity=28.4444444444444, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1786670, Length=227, Percent_Identity=23.3480176211454, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 91795; Mature: 91663

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPDYRIFFRRCAAFFLAGVLAAGSASAQQEAPPAAAPEQAEEAKAEQPQEQPDQSEMD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHH
TVIMALCHEITILKKNEEKRMAIRKTLVREADATYNYFDTRVYEMSAVLYALDDQKIFTL
HHHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
AFYCKAASSLVKTYYAQKPDFQGQEERLDKEIERIKKLAASLEEVNTDTLSQASLVQRDE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALYACQELEESLQSEKEQISYLKELFSSLNGKIDALNNESAKLFTALFNRVFYTPSHAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCE
YIFLKPHKTYETCMGAWETSADSKLQLPSDPETLKHYGLILLGIILCSYCLSRIIIFLGF
EEEECCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNTLKKTGHYNKRHAFANVTTILIVALILVIASLRTPNYLLESAASLGAEFLLLVSAILF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLVTRLPYGTINSGIRIYMPYLLLGGFFMLLRMFMAPNIIVDISMPILFTLVSLFSLLTW
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
VRQRHKLPRLDRFFSTVSLVFTILGSVLCWTGFSFMAFLVLMTWIMLMTSILLLVGLWDL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHHYENRRKERNKRAILWFRPFISKLLLPCLTIFLILFSIIWPAATFDMGDLIINKIFAT
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TEIKDLLTFSWSSVITVILMAIVLNYLIFLGKNTLHEIYGEDYEVGTIPTFVTLSTLFLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
GLFVFTALIIMNANYNGLLMVMGGLSMGIGFALKDTIENIISGLSLMLGRLRQGDMIECD
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GYRGRVSSLGYRSTMIETLDGSIIAFQNSQLFNKNFRNMTRNHKFECVKVEVGISYGTDV
CCCCHHHHCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCH
ERARKIILETLATLPFLSKVKKTSVVLDSFGDSAVNLGVWVWVPVMTKSSSLSSVREHIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEHHCCCCHHHHHHHHHH
NAFNEHGISIPFPQQDLYVKEFLGGAPVQGT
HHHHHCCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SIPDYRIFFRRCAAFFLAGVLAAGSASAQQEAPPAAAPEQAEEAKAEQPQEQPDQSEMD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHH
TVIMALCHEITILKKNEEKRMAIRKTLVREADATYNYFDTRVYEMSAVLYALDDQKIFTL
HHHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
AFYCKAASSLVKTYYAQKPDFQGQEERLDKEIERIKKLAASLEEVNTDTLSQASLVQRDE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALYACQELEESLQSEKEQISYLKELFSSLNGKIDALNNESAKLFTALFNRVFYTPSHAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCE
YIFLKPHKTYETCMGAWETSADSKLQLPSDPETLKHYGLILLGIILCSYCLSRIIIFLGF
EEEECCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNTLKKTGHYNKRHAFANVTTILIVALILVIASLRTPNYLLESAASLGAEFLLLVSAILF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLVTRLPYGTINSGIRIYMPYLLLGGFFMLLRMFMAPNIIVDISMPILFTLVSLFSLLTW
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
VRQRHKLPRLDRFFSTVSLVFTILGSVLCWTGFSFMAFLVLMTWIMLMTSILLLVGLWDL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHHYENRRKERNKRAILWFRPFISKLLLPCLTIFLILFSIIWPAATFDMGDLIINKIFAT
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TEIKDLLTFSWSSVITVILMAIVLNYLIFLGKNTLHEIYGEDYEVGTIPTFVTLSTLFLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
GLFVFTALIIMNANYNGLLMVMGGLSMGIGFALKDTIENIISGLSLMLGRLRQGDMIECD
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GYRGRVSSLGYRSTMIETLDGSIIAFQNSQLFNKNFRNMTRNHKFECVKVEVGISYGTDV
CCCCHHHHCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCH
ERARKIILETLATLPFLSKVKKTSVVLDSFGDSAVNLGVWVWVPVMTKSSSLSSVREHIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEHHCCCCHHHHHHHHHH
NAFNEHGISIPFPQQDLYVKEFLGGAPVQGT
HHHHHCCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]