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The map label for this gene is 187736342

Identifier: 187736342

GI number: 187736342

Start: 2261743

End: 2262678

Strand: Reverse

Name: 187736342

Synonym: Amuc_1859

Alternate gene names: NA

Gene position: 2262678-2261743 (Counterclockwise)

Preceding gene: 187736343

Following gene: 187736341

Centisome position: 84.93

GC content: 56.94

Gene sequence:

>936_bases
ATGAAAATCGCCATTCTGGGAGCCGGAGCCCTGGGTTGCTATTACGGAGCCAGACTTCAGGAATCGGGGCAGGACGTATC
CTTCATCGTACGTTCGGAATACGGCTATCTGAAAGAACACGGCCTTCAGGTGAAAAGCCTGCATGGGAATATCTCCCTGC
CCCGCATCAACGTTTACCGGGACACGGAGGAAGTCGGCCCGGTAGACCTCGTTGTCGTTGCATGGAAAAGCACGGCAAAC
GCCGGATTTTCCAGAGCTCTTCCTCCGTTGATGGGGCCGGACACAACTGTGGTTACACTCCAGAACGGCATGGGAAATGC
GGAGGAAATTGCCCGCATCATCCCGGCGGAGCGTATCTATGTGGGCCTGTGCTTCATCTGCGCTATGCGGGAAAAACCGG
GCCATGTCAACCATCTGGAAGGGGGCAACATCCAGTTCGCCCCCTTCATCCCCACGCCGGAAGGGACTGAAAAAGCCAGG
GAACTCTCCGAGCTGTTTGCCAATGCCGGCATCAAAACGCGCGCCTTTGACGCCGCAGAGCAAATCCAGTGGTACAAACT
CGTCTGGAACATCCCGTTTAACGGGCTTTGCCTGGCTCTGGGCGGCATCAGCATTGCGGAACTCTACCAAAATCCGGAAA
ACGTCGTACGCGCGCGCCGCATCATGGAAGAAGTAGTACAGGCAGCCAGGGCCCGCGGCTACGCCCTGCCGGAAGATTTG
GTTGAATTCCACCTTTCCCGTACGGAAACCATGGGGGCTTTCATCCCGTCCAGCGCCGTGGACTACAACGAAGGCCGCCC
CGTCGAATACACAGCTATCTGGGGAGACCCTCTCTCCAAGGCCCGGCAAGCCGGAGCCTTCGTGCCGGAATGGGAACTTC
TGGACAAAGCCATCCGCAAGCGCCTGAACATGAATAGTCCTTCTGATTCTATTTAA

Upstream 100 bases:

>100_bases
GCCCGCCCTTCCCGTCTCACCGAACGCCATGCACATCTACCTGGATGACAAGGGCAACGTCCAGGGGCTCTGAAAAATAT
CACCAACCGCGCCGCACGCC

Downstream 100 bases:

>100_bases
TAAACTAAAATGATACAAAGGTCTTATTATTTCAATGACCTACAGTCTTTTTGTACCCAAACTCTAGAAGAAATTTTAGG
GCAGATTGCTCTTCATACCC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKIAILGAGALGCYYGARLQESGQDVSFIVRSEYGYLKEHGLQVKSLHGNISLPRINVYRDTEEVGPVDLVVVAWKSTAN
AGFSRALPPLMGPDTTVVTLQNGMGNAEEIARIIPAERIYVGLCFICAMREKPGHVNHLEGGNIQFAPFIPTPEGTEKAR
ELSELFANAGIKTRAFDAAEQIQWYKLVWNIPFNGLCLALGGISIAELYQNPENVVRARRIMEEVVQAARARGYALPEDL
VEFHLSRTETMGAFIPSSAVDYNEGRPVEYTAIWGDPLSKARQAGAFVPEWELLDKAIRKRLNMNSPSDSI

Sequences:

>Translated_311_residues
MKIAILGAGALGCYYGARLQESGQDVSFIVRSEYGYLKEHGLQVKSLHGNISLPRINVYRDTEEVGPVDLVVVAWKSTAN
AGFSRALPPLMGPDTTVVTLQNGMGNAEEIARIIPAERIYVGLCFICAMREKPGHVNHLEGGNIQFAPFIPTPEGTEKAR
ELSELFANAGIKTRAFDAAEQIQWYKLVWNIPFNGLCLALGGISIAELYQNPENVVRARRIMEEVVQAARARGYALPEDL
VEFHLSRTETMGAFIPSSAVDYNEGRPVEYTAIWGDPLSKARQAGAFVPEWELLDKAIRKRLNMNSPSDSI
>Mature_311_residues
MKIAILGAGALGCYYGARLQESGQDVSFIVRSEYGYLKEHGLQVKSLHGNISLPRINVYRDTEEVGPVDLVVVAWKSTAN
AGFSRALPPLMGPDTTVVTLQNGMGNAEEIARIIPAERIYVGLCFICAMREKPGHVNHLEGGNIQFAPFIPTPEGTEKAR
ELSELFANAGIKTRAFDAAEQIQWYKLVWNIPFNGLCLALGGISIAELYQNPENVVRARRIMEEVVQAARARGYALPEDL
VEFHLSRTETMGAFIPSSAVDYNEGRPVEYTAIWGDPLSKARQAGAFVPEWELLDKAIRKRLNMNSPSDSI

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34280; Mature: 34280

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAILGAGALGCYYGARLQESGQDVSFIVRSEYGYLKEHGLQVKSLHGNISLPRINVYR
CEEEEEECCHHHHHHCCHHHCCCCCEEEEEECCCCHHHHCCCEEEEECCCCCCCEEEEEE
DTEEVGPVDLVVVAWKSTANAGFSRALPPLMGPDTTVVTLQNGMGNAEEIARIIPAERIY
CCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHH
VGLCFICAMREKPGHVNHLEGGNIQFAPFIPTPEGTEKARELSELFANAGIKTRAFDAAE
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
QIQWYKLVWNIPFNGLCLALGGISIAELYQNPENVVRARRIMEEVVQAARARGYALPEDL
HHEEEEEEEECCCCCEEEHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VEFHLSRTETMGAFIPSSAVDYNEGRPVEYTAIWGDPLSKARQAGAFVPEWELLDKAIRK
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHH
RLNMNSPSDSI
HCCCCCCCCCC
>Mature Secondary Structure
MKIAILGAGALGCYYGARLQESGQDVSFIVRSEYGYLKEHGLQVKSLHGNISLPRINVYR
CEEEEEECCHHHHHHCCHHHCCCCCEEEEEECCCCHHHHCCCEEEEECCCCCCCEEEEEE
DTEEVGPVDLVVVAWKSTANAGFSRALPPLMGPDTTVVTLQNGMGNAEEIARIIPAERIY
CCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHH
VGLCFICAMREKPGHVNHLEGGNIQFAPFIPTPEGTEKARELSELFANAGIKTRAFDAAE
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
QIQWYKLVWNIPFNGLCLALGGISIAELYQNPENVVRARRIMEEVVQAARARGYALPEDL
HHEEEEEEEECCCCCEEEHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VEFHLSRTETMGAFIPSSAVDYNEGRPVEYTAIWGDPLSKARQAGAFVPEWELLDKAIRK
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHH
RLNMNSPSDSI
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]