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The map label for this gene is ydeN [H]

Identifier: 187736242

GI number: 187736242

Start: 2136730

End: 2138418

Strand: Reverse

Name: ydeN [H]

Synonym: Amuc_1755

Alternate gene names: 187736242

Gene position: 2138418-2136730 (Counterclockwise)

Preceding gene: 187736243

Following gene: 187736241

Centisome position: 80.27

GC content: 57.67

Gene sequence:

>1689_bases
ATGAACATTTCCCGTATTGCAGCCTTTCTCATCCCGTTCCTGCTGGGAAGCGCCTGCTCTGCTTCCGCAGCTTCCGTAAA
AGCATCCCGCGCGGCAGAACCGAAACGCCCCAACATCATCCTCTTTCTGGTGGACGACATGGGCTGGCAGGATACATCCC
TGCCCTTTTGGCGGGAAGAGGACGGCACTCCCAAACCTACTTTCCTGAACAAGCGCTACCGCACGCCCAACATGGAGGCT
CTGGGCAAGCAGGGCATGGTCTTCACGAACGCCTACGCGCAGCCTATCTGTTCCCCCAGCCGATGCAGCCTCATGTCCGG
CATGAACTCCGCCCGCCACCGCGTCACGAACTGGACGCTCCTGCGTGACCAAACCACGGACGCAGGCCATCAAGCGCTCA
AGGCTCCCGCAGACTGGAGCGTCAACGGCATCCAGCCGGCAGGAACCAGGGCATCCGGAACCACCCATCTTCCCCTGACG
GAAGAAAAAATCCAGTACAGGATGGAAAAACCCTTCACCCAGGTGCTTGGGCTGCCCGCCCTGCTCAAAAAACAGGGGTA
TACCACCATCCACTGCGGAAAAGCCCATTTCGGCTCCAAAAATACGCCCGGAGCCAATCCCAGGCTCTTCGGCTTTGACT
ACAATATCGCCGGCACGGAAATAGGCGGCCCGGCGGACTACCGGGGTTCCCGGAAATACGGCACGGGGAATTTCCATGTC
CGCGGACTGGATGAAAATAATTACTATGAAAACGACACATTCCTGACGGAAGCCCTGACGCAGGAGGCACTGAAACGCCT
GGACGCCATCCGGAAAAACCCCAGGGAGGCGGACAAGCCTTTCTACCTGTACATGTCCCACTACGCCATCCATGCCCCCT
TCGACATGCGCGGTTATGACAAGAGGTTTGCGGAAGAGTACTCCAACCCCAATGACGGCCACAAATGGTCCGACAACGAA
AAACGCTATTCCGCCCTGATCCAGGGGATGGACAAGAGCCTGGGCGACATCCGGGAATACCTGAAAAAAAACAATCTGGA
TAAAAATACCGTCATCATCTTCATGGCGGACAACGGGGGCCTTGCCATCAGCGGGCGCATGGGCAACAAGGAATCCAATT
ACCCGCTTAGCTTCGGCAAGGGTTCCAACCGGGAAGGCGGCATCCGGGAACCGATGATCGTCTACTGGCCCGGGGTCACG
AAGGCGGAAAGCGTCTGCACTACTCCCGTCATCATTGAAGACTTTTTCCCCACCATTCTGGAAATAGCAGGAGCAAAAAA
AATTCAGGCGCCTCAGGTTGTGGACGGCAAAAGCTTTGTTGCCCTGCTGAAAGGCGGCAGCATGAATCCCAACCGCTCCC
TGCTCTTCCACACGCCCAACGTATGGGGGGAAGGGAACGGAAACAACTCCCTTTATTCCCCCAGCACGGCCATGCGCCAG
GGGGACTGGAAGCTTATCTACTGGCACCCTGACCAGAAGTTCGAACTCTTCAACCTCAAGGAGGACATCAGCGAAGAGCA
CAACCTGGCGGAACAGCAGCCGGAACGCGTTAAGGTCATGGCCAGGACCATGACCACCCTGCTCAAGGAGCGCAAGGCCC
AAATGCCCACCTACAAGAAGAATAATCCCGCCGGAGCCCGTGAAGGCGCTCCCGTACCGTGGCCGGACCAGGCGGCGGCC
AGGCTGTAA

Upstream 100 bases:

>100_bases
AAAAACGGGGCGTTCCCGAACAAACTGCCGCGGGAATACGAATCCTTGACAGAAACGTCCGTCTCATGCGTTATTATAAT
AAGTACTGGTTTTCTTAGTA

Downstream 100 bases:

>100_bases
GTAAAGGCATCTCCATCCCTCCCTGGAAAGCCGCATTATTCCCTTTTCTTTTAAGAAAACAGGGAGTATGGTGCGGCTTT
CCCGTTTTTATTCCCTTTCA

Product: sulfatase

Products: A Phenol; Sulfate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MNISRIAAFLIPFLLGSACSASAASVKASRAAEPKRPNIILFLVDDMGWQDTSLPFWREEDGTPKPTFLNKRYRTPNMEA
LGKQGMVFTNAYAQPICSPSRCSLMSGMNSARHRVTNWTLLRDQTTDAGHQALKAPADWSVNGIQPAGTRASGTTHLPLT
EEKIQYRMEKPFTQVLGLPALLKKQGYTTIHCGKAHFGSKNTPGANPRLFGFDYNIAGTEIGGPADYRGSRKYGTGNFHV
RGLDENNYYENDTFLTEALTQEALKRLDAIRKNPREADKPFYLYMSHYAIHAPFDMRGYDKRFAEEYSNPNDGHKWSDNE
KRYSALIQGMDKSLGDIREYLKKNNLDKNTVIIFMADNGGLAISGRMGNKESNYPLSFGKGSNREGGIREPMIVYWPGVT
KAESVCTTPVIIEDFFPTILEIAGAKKIQAPQVVDGKSFVALLKGGSMNPNRSLLFHTPNVWGEGNGNNSLYSPSTAMRQ
GDWKLIYWHPDQKFELFNLKEDISEEHNLAEQQPERVKVMARTMTTLLKERKAQMPTYKKNNPAGAREGAPVPWPDQAAA
RL

Sequences:

>Translated_562_residues
MNISRIAAFLIPFLLGSACSASAASVKASRAAEPKRPNIILFLVDDMGWQDTSLPFWREEDGTPKPTFLNKRYRTPNMEA
LGKQGMVFTNAYAQPICSPSRCSLMSGMNSARHRVTNWTLLRDQTTDAGHQALKAPADWSVNGIQPAGTRASGTTHLPLT
EEKIQYRMEKPFTQVLGLPALLKKQGYTTIHCGKAHFGSKNTPGANPRLFGFDYNIAGTEIGGPADYRGSRKYGTGNFHV
RGLDENNYYENDTFLTEALTQEALKRLDAIRKNPREADKPFYLYMSHYAIHAPFDMRGYDKRFAEEYSNPNDGHKWSDNE
KRYSALIQGMDKSLGDIREYLKKNNLDKNTVIIFMADNGGLAISGRMGNKESNYPLSFGKGSNREGGIREPMIVYWPGVT
KAESVCTTPVIIEDFFPTILEIAGAKKIQAPQVVDGKSFVALLKGGSMNPNRSLLFHTPNVWGEGNGNNSLYSPSTAMRQ
GDWKLIYWHPDQKFELFNLKEDISEEHNLAEQQPERVKVMARTMTTLLKERKAQMPTYKKNNPAGAREGAPVPWPDQAAA
RL
>Mature_562_residues
MNISRIAAFLIPFLLGSACSASAASVKASRAAEPKRPNIILFLVDDMGWQDTSLPFWREEDGTPKPTFLNKRYRTPNMEA
LGKQGMVFTNAYAQPICSPSRCSLMSGMNSARHRVTNWTLLRDQTTDAGHQALKAPADWSVNGIQPAGTRASGTTHLPLT
EEKIQYRMEKPFTQVLGLPALLKKQGYTTIHCGKAHFGSKNTPGANPRLFGFDYNIAGTEIGGPADYRGSRKYGTGNFHV
RGLDENNYYENDTFLTEALTQEALKRLDAIRKNPREADKPFYLYMSHYAIHAPFDMRGYDKRFAEEYSNPNDGHKWSDNE
KRYSALIQGMDKSLGDIREYLKKNNLDKNTVIIFMADNGGLAISGRMGNKESNYPLSFGKGSNREGGIREPMIVYWPGVT
KAESVCTTPVIIEDFFPTILEIAGAKKIQAPQVVDGKSFVALLKGGSMNPNRSLLFHTPNVWGEGNGNNSLYSPSTAMRQ
GDWKLIYWHPDQKFELFNLKEDISEEHNLAEQQPERVKVMARTMTTLLKERKAQMPTYKKNNPAGAREGAPVPWPDQAAA
RL

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=536, Percent_Identity=25.3731343283582, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI38569405, Length=560, Percent_Identity=26.6071428571429, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4503899, Length=436, Percent_Identity=30.9633027522936, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI38569407, Length=436, Percent_Identity=28.8990825688073, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI59797060, Length=559, Percent_Identity=23.7924865831843, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI53831991, Length=502, Percent_Identity=25.0996015936255, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI45430057, Length=546, Percent_Identity=24.3589743589744, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI157266309, Length=582, Percent_Identity=23.8831615120275, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI146229331, Length=500, Percent_Identity=23.2, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI146229329, Length=500, Percent_Identity=23.2, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI6005990, Length=500, Percent_Identity=23.2, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI146229324, Length=500, Percent_Identity=23.2, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI146229327, Length=264, Percent_Identity=26.1363636363636, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI39930577, Length=221, Percent_Identity=26.6968325791855, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI71852584, Length=199, Percent_Identity=27.1356783919598, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1790233, Length=431, Percent_Identity=26.2180974477958, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI87081924, Length=550, Percent_Identity=25.0909090909091, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115533416, Length=517, Percent_Identity=23.5976789168279, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115533418, Length=509, Percent_Identity=23.5756385068762, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281363223, Length=491, Percent_Identity=27.4949083503055, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24666109, Length=472, Percent_Identity=26.271186440678, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281366397, Length=492, Percent_Identity=23.780487804878, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281366395, Length=492, Percent_Identity=23.780487804878, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24666163, Length=492, Percent_Identity=23.780487804878, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24666175, Length=435, Percent_Identity=25.2873563218391, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.1 [C]

Molecular weight: Translated: 62850; Mature: 62850

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISRIAAFLIPFLLGSACSASAASVKASRAAEPKRPNIILFLVDDMGWQDTSLPFWREE
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEECC
DGTPKPTFLNKRYRTPNMEALGKQGMVFTNAYAQPICSPSRCSLMSGMNSARHRVTNWTL
CCCCCCCCCCCCCCCCCHHHHCCCCEEEECHHHCCCCCCHHHHHHHCCCHHHHHHCEEEE
LRDQTTDAGHQALKAPADWSVNGIQPAGTRASGTTHLPLTEEKIQYRMEKPFTQVLGLPA
EECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHCCHH
LLKKQGYTTIHCGKAHFGSKNTPGANPRLFGFDYNIAGTEIGGPADYRGSRKYGTGNFHV
HHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEE
RGLDENNYYENDTFLTEALTQEALKRLDAIRKNPREADKPFYLYMSHYAIHAPFDMRGYD
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCHH
KRFAEEYSNPNDGHKWSDNEKRYSALIQGMDKSLGDIREYLKKNNLDKNTVIIFMADNGG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
LAISGRMGNKESNYPLSFGKGSNREGGIREPMIVYWPGVTKAESVCTTPVIIEDFFPTIL
EEEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHH
EIAGAKKIQAPQVVDGKSFVALLKGGSMNPNRSLLFHTPNVWGEGNGNNSLYSPSTAMRQ
HHHCCCCCCCCCEECCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEECCHHHHHC
GDWKLIYWHPDQKFELFNLKEDISEEHNLAEQQPERVKVMARTMTTLLKERKAQMPTYKK
CCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
NNPAGAREGAPVPWPDQAAARL
CCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MNISRIAAFLIPFLLGSACSASAASVKASRAAEPKRPNIILFLVDDMGWQDTSLPFWREE
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEECC
DGTPKPTFLNKRYRTPNMEALGKQGMVFTNAYAQPICSPSRCSLMSGMNSARHRVTNWTL
CCCCCCCCCCCCCCCCCHHHHCCCCEEEECHHHCCCCCCHHHHHHHCCCHHHHHHCEEEE
LRDQTTDAGHQALKAPADWSVNGIQPAGTRASGTTHLPLTEEKIQYRMEKPFTQVLGLPA
EECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHCCHH
LLKKQGYTTIHCGKAHFGSKNTPGANPRLFGFDYNIAGTEIGGPADYRGSRKYGTGNFHV
HHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEE
RGLDENNYYENDTFLTEALTQEALKRLDAIRKNPREADKPFYLYMSHYAIHAPFDMRGYD
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCHH
KRFAEEYSNPNDGHKWSDNEKRYSALIQGMDKSLGDIREYLKKNNLDKNTVIIFMADNGG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
LAISGRMGNKESNYPLSFGKGSNREGGIREPMIVYWPGVTKAESVCTTPVIIEDFFPTIL
EEEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHH
EIAGAKKIQAPQVVDGKSFVALLKGGSMNPNRSLLFHTPNVWGEGNGNNSLYSPSTAMRQ
HHHCCCCCCCCCEECCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEECCHHHHHC
GDWKLIYWHPDQKFELFNLKEDISEEHNLAEQQPERVKVMARTMTTLLKERKAQMPTYKK
CCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
NNPAGAREGAPVPWPDQAAARL
CCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Phenol Sulfate; H2O [C]

Specific reaction: A Phenol Sulfate + H2O = A Phenol + Sulfate. [C]

General reaction: Sulfuric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]