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The map label for this gene is 187736228

Identifier: 187736228

GI number: 187736228

Start: 2121618

End: 2123003

Strand: Reverse

Name: 187736228

Synonym: Amuc_1741

Alternate gene names: NA

Gene position: 2123003-2121618 (Counterclockwise)

Preceding gene: 187736229

Following gene: 187736227

Centisome position: 79.69

GC content: 61.62

Gene sequence:

>1386_bases
ATGAGTACGTTCACTCCTTTTGCGGAAAAGATGGAGTCCGCCGGCGTTTCAGCCGCGGCCGTCAACGCTTTCTCCCGTTG
TTATGAAGCCCTTGTTTCCAACCACTCCGGCATGATTCCGGAAACGGACATCCTGCCCGCCGACCAGGTGGAAGACTGGC
AGGACATCACGGCCTCCACCCCCGCGGCGGACAAGGACCTGATTTCCCGTTGCGTATGCATCAAGCTCAACGGCGGCCTC
GGCACGAGCATGGGCCTCCAGAAAGCGAAAAGCCTGCTGAAAGTAAAAGGAGAGGATACGTTCCTGGATTTGATCGTCAG
GCAGGTGAAGCATCTGCGCTCCATCTCCGGCACGCCTGTGCGCCTTCTGCTGATGAACTCTTTCTCCACCAGCGCGGACA
CGCTGGCCTACCTGGAAAAATACGCGGCGGACGGCTTTGCGGACCGCGCCGAAGTGGAGCTGCTGCAAAACCGCGTTCCC
AAAATCCTGGCGGACGGCCTCTCCCCGGCCAGCTGCCCGGAACAGCCGGAGCTGGAATGGTGCCCGCCAGGCCATGGGGA
CCTGTATCCGGCCCTGCTGGGGTCCGGCTGGCTGGACCGCCTGCTGGAGGATGGCGTTAAATACGCTTTTGTCTCCAATT
CCGACAATCTGGGCGCCCAGCTTGACATGAACTTCCTCCGCTGGTTTGCGGAAAGCGGCGCCCCCTTCGTCATGGAAGTC
ACCCGCCGCACGGTGGCGGACAGGAAAGGCGGCCACCTGGCTGTCAGGAAATCGGACGGCCAGTTGATTCTGCGGGAAGT
GGCCCAGTGCCCGGATGAGGACATTCCTGAATTCCAGAACATTTCCAGGCACCGCTATTTCAACACCAATACGCTCTGGA
TACGCCTGGACGCCCTCAAGGAAATTCTGGACGCCAACGGCGGCGTACTCCCGCTGCCCATGATCCGTAATAAAAAGACG
CTCAACCCCCGCGATCCGGAATCCGCCCCGGTGTACCAGCTGGAAACGGCCATGGGCGCGGGCATCGAATGCTTCCCCGG
CGCCAGGGCCGTCAACGTCCCGCGTTCCCGTTTCTTCCCCGTCAAAACCACTTCCGACCTGTTCCTGCTCCGTTCGGACG
CCATCGCCGTGGATGAACACGGCAACGTGGCCCTGGCGCCGGAACGGCAGGGCAACACCCCGGTGGTGGACCTGGATTCC
AAACTGTACAAGCTGGTGGATTCCCTGGACGGGCTGGGCCTGCCCTCCCTGATAGGCATGGACAAGCTGACCCTGCGCGG
CCGCTTCCACTTCCAGGACGGAGCCGTTCTCCGGGGCACCTTGCTGATGGAAAACGACTCCGACGAAACGAAGGAAATCC
TCCCGGGCGTCTATGCCGGAGCCTGA

Upstream 100 bases:

>100_bases
AACCCGGAGCAGTCCCCGCAAGAAAGAGAAAACGCGCGGGCATTCCGGATACGCTGATAATGCTTGAGCCTCCTCCGGGC
ATTTTGTACAAAAGCCGCCA

Downstream 100 bases:

>100_bases
ACGCCATCTTCCCGCTTCCGCGCCCCGTCCGGTTCAGGCCGGTCTGGGCGTGGAGGACATCCGGCACATTCCCGTCCGGA
AACGGGAGTTGCGCTTCACC

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: diphosphate; UDP-glucose

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSTFTPFAEKMESAGVSAAAVNAFSRCYEALVSNHSGMIPETDILPADQVEDWQDITASTPAADKDLISRCVCIKLNGGL
GTSMGLQKAKSLLKVKGEDTFLDLIVRQVKHLRSISGTPVRLLLMNSFSTSADTLAYLEKYAADGFADRAEVELLQNRVP
KILADGLSPASCPEQPELEWCPPGHGDLYPALLGSGWLDRLLEDGVKYAFVSNSDNLGAQLDMNFLRWFAESGAPFVMEV
TRRTVADRKGGHLAVRKSDGQLILREVAQCPDEDIPEFQNISRHRYFNTNTLWIRLDALKEILDANGGVLPLPMIRNKKT
LNPRDPESAPVYQLETAMGAGIECFPGARAVNVPRSRFFPVKTTSDLFLLRSDAIAVDEHGNVALAPERQGNTPVVDLDS
KLYKLVDSLDGLGLPSLIGMDKLTLRGRFHFQDGAVLRGTLLMENDSDETKEILPGVYAGA

Sequences:

>Translated_461_residues
MSTFTPFAEKMESAGVSAAAVNAFSRCYEALVSNHSGMIPETDILPADQVEDWQDITASTPAADKDLISRCVCIKLNGGL
GTSMGLQKAKSLLKVKGEDTFLDLIVRQVKHLRSISGTPVRLLLMNSFSTSADTLAYLEKYAADGFADRAEVELLQNRVP
KILADGLSPASCPEQPELEWCPPGHGDLYPALLGSGWLDRLLEDGVKYAFVSNSDNLGAQLDMNFLRWFAESGAPFVMEV
TRRTVADRKGGHLAVRKSDGQLILREVAQCPDEDIPEFQNISRHRYFNTNTLWIRLDALKEILDANGGVLPLPMIRNKKT
LNPRDPESAPVYQLETAMGAGIECFPGARAVNVPRSRFFPVKTTSDLFLLRSDAIAVDEHGNVALAPERQGNTPVVDLDS
KLYKLVDSLDGLGLPSLIGMDKLTLRGRFHFQDGAVLRGTLLMENDSDETKEILPGVYAGA
>Mature_460_residues
STFTPFAEKMESAGVSAAAVNAFSRCYEALVSNHSGMIPETDILPADQVEDWQDITASTPAADKDLISRCVCIKLNGGLG
TSMGLQKAKSLLKVKGEDTFLDLIVRQVKHLRSISGTPVRLLLMNSFSTSADTLAYLEKYAADGFADRAEVELLQNRVPK
ILADGLSPASCPEQPELEWCPPGHGDLYPALLGSGWLDRLLEDGVKYAFVSNSDNLGAQLDMNFLRWFAESGAPFVMEVT
RRTVADRKGGHLAVRKSDGQLILREVAQCPDEDIPEFQNISRHRYFNTNTLWIRLDALKEILDANGGVLPLPMIRNKKTL
NPRDPESAPVYQLETAMGAGIECFPGARAVNVPRSRFFPVKTTSDLFLLRSDAIAVDEHGNVALAPERQGNTPVVDLDSK
LYKLVDSLDGLGLPSLIGMDKLTLRGRFHFQDGAVLRGTLLMENDSDETKEILPGVYAGA

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI48255968, Length=425, Percent_Identity=39.0588235294118, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI48255966, Length=425, Percent_Identity=39.0588235294118, Blast_Score=272, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17554114, Length=408, Percent_Identity=41.1764705882353, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71988370, Length=408, Percent_Identity=41.1764705882353, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17554112, Length=408, Percent_Identity=41.1764705882353, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71988365, Length=408, Percent_Identity=41.1764705882353, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17554108, Length=408, Percent_Identity=41.1764705882353, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17554110, Length=386, Percent_Identity=40.9326424870466, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI25151022, Length=395, Percent_Identity=33.6708860759494, Blast_Score=204, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6322815, Length=399, Percent_Identity=43.1077694235589, Blast_Score=286, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6321775, Length=406, Percent_Identity=30.7881773399015, Blast_Score=159, Evalue=9e-40,
Organism=Drosophila melanogaster, GI281365929, Length=411, Percent_Identity=38.1995133819951, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI281365931, Length=411, Percent_Identity=38.1995133819951, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI62484452, Length=413, Percent_Identity=38.0145278450363, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI62484278, Length=413, Percent_Identity=38.0145278450363, Blast_Score=256, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.9

Molecular weight: Translated: 50437; Mature: 50306

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFTPFAEKMESAGVSAAAVNAFSRCYEALVSNHSGMIPETDILPADQVEDWQDITAST
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCC
PAADKDLISRCVCIKLNGGLGTSMGLQKAKSLLKVKGEDTFLDLIVRQVKHLRSISGTPV
CCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCE
RLLLMNSFSTSADTLAYLEKYAADGFADRAEVELLQNRVPKILADGLSPASCPEQPELEW
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
CPPGHGDLYPALLGSGWLDRLLEDGVKYAFVSNSDNLGAQLDMNFLRWFAESGAPFVMEV
CCCCCCCCHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCEECHHHHHHHHHCCCCEEHHH
TRRTVADRKGGHLAVRKSDGQLILREVAQCPDEDIPEFQNISRHRYFNTNTLWIRLDALK
HHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHCCCHHEEECCCEEEEEHHHHH
EILDANGGVLPLPMIRNKKTLNPRDPESAPVYQLETAMGAGIECFPGARAVNVPRSRFFP
HHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCEECCCCCEECCCHHHEEC
VKTTSDLFLLRSDAIAVDEHGNVALAPERQGNTPVVDLDSKLYKLVDSLDGLGLPSLIGM
CCCCCCEEEEECCCEEEECCCCEEECCCCCCCCCEEECHHHHHHHHHHHCCCCCCHHHCC
DKLTLRGRFHFQDGAVLRGTLLMENDSDETKEILPGVYAGA
CCEEEEEEEEECCCCEEEEEEEEECCCCHHHHHCCCHHCCC
>Mature Secondary Structure 
STFTPFAEKMESAGVSAAAVNAFSRCYEALVSNHSGMIPETDILPADQVEDWQDITAST
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCC
PAADKDLISRCVCIKLNGGLGTSMGLQKAKSLLKVKGEDTFLDLIVRQVKHLRSISGTPV
CCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCE
RLLLMNSFSTSADTLAYLEKYAADGFADRAEVELLQNRVPKILADGLSPASCPEQPELEW
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
CPPGHGDLYPALLGSGWLDRLLEDGVKYAFVSNSDNLGAQLDMNFLRWFAESGAPFVMEV
CCCCCCCCHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCEECHHHHHHHHHCCCCEEHHH
TRRTVADRKGGHLAVRKSDGQLILREVAQCPDEDIPEFQNISRHRYFNTNTLWIRLDALK
HHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHCCCHHEEECCCEEEEEHHHHH
EILDANGGVLPLPMIRNKKTLNPRDPESAPVYQLETAMGAGIECFPGARAVNVPRSRFFP
HHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCEECCCCCEECCCHHHEEC
VKTTSDLFLLRSDAIAVDEHGNVALAPERQGNTPVVDLDSKLYKLVDSLDGLGLPSLIGM
CCCCCCEEEEECCCEEEECCCCEEECCCCCCCCCEEECHHHHHHHHHHHCCCCCCHHHCC
DKLTLRGRFHFQDGAVLRGTLLMENDSDETKEILPGVYAGA
CCEEEEEEEEECCCCEEEEEEEEECCCCHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; alpha-D-glucose 1-phosphate

Specific reaction: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA