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The map label for this gene is infC [H]

Identifier: 187736220

GI number: 187736220

Start: 2116335

End: 2116973

Strand: Direct

Name: infC [H]

Synonym: Amuc_1733

Alternate gene names: 187736220

Gene position: 2116335-2116973 (Clockwise)

Preceding gene: 187736219

Following gene: 187736221

Centisome position: 79.44

GC content: 57.75

Gene sequence:

>639_bases
GTGCCAACCAAGCCAACGAAGAATAATGACGGAAATCGCCGCCGTGACCGCGGCGATCAGACTCGGATCAATGAACGGAT
TCGCGCGCCCCGCGTGCGGGTAGTGACTGCCAACGGCGACCAGCTGGGCGTCATGAACACGCGCGACGCGCTGGAAAAAG
CCAAGGCTCTGGGTCTGGACCTGGTGGAAGTGGCCGGCAATGCCGATCCGCCCGTATGCCGCGTGGTTGATTACGGCAAG
TACAAATACCAGCAGGCCAAGCTCCAGAAAAACAACAAGAGCCGAACCGTCAAGCTTAAGGAAATCAAGCTCCGCATCGG
TACGGATACCAATGACTATAATGTGAAAATGGCCCGTACGGAAAGCTTCTTGGACCATGGCCACAAGGTCCGCTTCCAGC
TCCGTTTCCGCGGTCGTGAGAACGCCCACCAGGAGCTTGGCTACGACGTCTTCAACAAAGTCATCGCGGATATGAAGACC
ATGGCGCAGGTGGATCAGGCCCCGCGTTTGGCCGGCAACACCATGCACATGGTGCTCTCCCCGCTCCCCGCCCAGCAGCG
CGTGAAGAAATTCACCGCCCACCTGGATAAGGATTTTGATTCCGAAGATTCCGCCTTTGACGCGGAGGATGACGAGTAA

Upstream 100 bases:

>100_bases
GCAATTCGCGGACCTCGTAGCCCGGGAAATCGCGGAGCGTCATATTTCTCCCGTGATTTGAGTTGCCAAGTTATTCCTTT
TAGTTTAGTAGTATCCGGAC

Downstream 100 bases:

>100_bases
GACGGCATTTTTTTCTTTTTCAGGCTTTCCACCCTTATAAGGGTGGAAAGCCTTTTTTACGGGCAGATGATTTTCCATGG
CTCTTTTCTATAATGATACT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MPTKPTKNNDGNRRRDRGDQTRINERIRAPRVRVVTANGDQLGVMNTRDALEKAKALGLDLVEVAGNADPPVCRVVDYGK
YKYQQAKLQKNNKSRTVKLKEIKLRIGTDTNDYNVKMARTESFLDHGHKVRFQLRFRGRENAHQELGYDVFNKVIADMKT
MAQVDQAPRLAGNTMHMVLSPLPAQQRVKKFTAHLDKDFDSEDSAFDAEDDE

Sequences:

>Translated_212_residues
MPTKPTKNNDGNRRRDRGDQTRINERIRAPRVRVVTANGDQLGVMNTRDALEKAKALGLDLVEVAGNADPPVCRVVDYGK
YKYQQAKLQKNNKSRTVKLKEIKLRIGTDTNDYNVKMARTESFLDHGHKVRFQLRFRGRENAHQELGYDVFNKVIADMKT
MAQVDQAPRLAGNTMHMVLSPLPAQQRVKKFTAHLDKDFDSEDSAFDAEDDE
>Mature_211_residues
PTKPTKNNDGNRRRDRGDQTRINERIRAPRVRVVTANGDQLGVMNTRDALEKAKALGLDLVEVAGNADPPVCRVVDYGKY
KYQQAKLQKNNKSRTVKLKEIKLRIGTDTNDYNVKMARTESFLDHGHKVRFQLRFRGRENAHQELGYDVFNKVIADMKTM
AQVDQAPRLAGNTMHMVLSPLPAQQRVKKFTAHLDKDFDSEDSAFDAEDDE

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=174, Percent_Identity=44.8275862068966, Blast_Score=154, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 24184; Mature: 24052

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTKPTKNNDGNRRRDRGDQTRINERIRAPRVRVVTANGDQLGVMNTRDALEKAKALGLD
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCEECCCCHHHHHHHHHHHCCH
LVEVAGNADPPVCRVVDYGKYKYQQAKLQKNNKSRTVKLKEIKLRIGTDTNDYNVKMART
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEEHHH
ESFLDHGHKVRFQLRFRGRENAHQELGYDVFNKVIADMKTMAQVDQAPRLAGNTMHMVLS
HHHHCCCCEEEEEEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEC
PLPAQQRVKKFTAHLDKDFDSEDSAFDAEDDE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PTKPTKNNDGNRRRDRGDQTRINERIRAPRVRVVTANGDQLGVMNTRDALEKAKALGLD
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCEECCCCHHHHHHHHHHHCCH
LVEVAGNADPPVCRVVDYGKYKYQQAKLQKNNKSRTVKLKEIKLRIGTDTNDYNVKMART
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEEHHH
ESFLDHGHKVRFQLRFRGRENAHQELGYDVFNKVIADMKTMAQVDQAPRLAGNTMHMVLS
HHHHCCCCEEEEEEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEC
PLPAQQRVKKFTAHLDKDFDSEDSAFDAEDDE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9370368 [H]