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The map label for this gene is yycG [H]

Identifier: 187736214

GI number: 187736214

Start: 2108592

End: 2110229

Strand: Reverse

Name: yycG [H]

Synonym: Amuc_1727

Alternate gene names: 187736214

Gene position: 2110229-2108592 (Counterclockwise)

Preceding gene: 187736215

Following gene: 187736213

Centisome position: 79.21

GC content: 59.83

Gene sequence:

>1638_bases
GTGAACCGGCGCATACGCATCATTCTGCTGGCAATCAGCCTGCTGCTGGTCATCGGCACGCTCGGATGGCTCACCCATGT
TCTGCTGGTGCAGGCGGAAGAAACAGGCCATTCCGAACAGCGTATCAGGGTGGAAGCCCTGGCCCATGAAGCCAAGCTGG
AAATGGACCGCCTTCTGACCTCCTTCATCACATTCGAACAGGCCCGCGGCTATTTTGAATACCAGCCCGTTTACGCCTAC
AAACGCCCCTATGACCTGAGGATGGGCGCCCCGGCCCCCGGAGAAGCAACCCGTGGTTCCAATCTCGCCGCCTACCTGCC
GGACTACGTTACAGCCTTCATTCAGATTTCCCCTGCCGGGCGCGTAACCGGCCCCGCTCTTCCCCCGGAGCTTGCCGGGC
GGCTGAATGAACAGAAGGACCTTTACCAGCGGCTGAACGGCAAGGTCTCCTCCCTTACCTCCGTTCCGTCCAGCGGAAAC
CTCTGGACGGATATCCGGAATGAAATTCTGCATGAATCTCCGGAACCGGAGCCAACGGTATCCGGCTCTCCGGCACAAGT
GGAAACTGTCACTTCCTTCGTTCCCGTGGAAGACGGAGGGAACCTTTACATCCTGCGCCAGGTGCACACCAGCCGCGGCA
TTTATTTGCAGGGGGCCCTGATGAACATGGACAATCTGAACAGACGCCTGCCCGGCCAGGTAAAGATGCTGCTTCCCCAC
AGCCGCCTGGCAACCTTTAACCCGTCCTCCCCGCCCCCGGAGGAACCCCGGCAGGCGGGCGCACTCCCCTTTGCCAACGC
CCCTCTGATTTTCCTTCCGGGAGACACCGGAGCCGTTCCTCTCCAGGACCACAAAAAAATGCTGACCTGGACGCTCACCC
TCATCTGGAGCATGGTGCTCCTGGGTGCGGCTGGGGTCATCTGGCTCATGCTGGGAACCTTCCGCCTGGAACAGCGCCGC
GGGGACTTCGTCTCCGCCGTCACCCATGAACTCCGGACGCCCCTCACGTCCTTCTCCCTGTACACGGAAATGCTGGAAGA
CGGCATGGTGCCGGAACAGAAAAAGCCGGAATACTATGCCAACATGCAGCGGGAATGCCGCCGTCTGGAACACCTGATTG
AAAACGTACTCTCCTACTCCCGGCTTCAGCGGAACGCTATTCGCCGCGCGCGGGACACGCTCACCTGTCAGGAGCTTTTT
GAACCCATTGCGGAAAAAATAGAACGCCGCCTCCGGGAGGCGGACATCAGCTTCTCCTTTGCCCTGGCCCAGCCCATCCG
CATCCTTCCTATTCATACGGATGCCGTTTCCGTAGAGCAGATTATGGACAACCTGACTTCCAACGCCATTAAATACGCCA
AGGGGGAAAACGCCAAAGTCCAGCTCACCGTCCAGGCGGACCGCCACAACATCGTCATCCGCTTCCGCGACAACGGCCCA
GGAATTTCCCCGAAAAACCGCAAGCTTGTCTTCAAGCCCTTCCGGCGCACAAAAGACGCTACCAACAGCCGGAAACCCGG
CGTAGGCCTGGGGCTGGCGCTGGCAAGGGATACGGCACGTTCCCTGGGGGGAGACCTGAAACTGGAATTCGGCACCCTGG
GGGGAGCCAGCTTTCTGCTGACGATTCCCAAATCCTGA

Upstream 100 bases:

>100_bases
CATGCGTCTCCGGGACAAGCTCGGGGCCGCCTCCGCCTCCCCCCTGGAGACGCTTAGAAGCCAGGGCTACCGCTGGAATT
CATCCTTCGTTTCCTGATCC

Downstream 100 bases:

>100_bases
ACCTGCCAGCGGGACAGCCGGGAACCAACCGGAATTCGCCTCCCGGTCCGTACGGAAAAACCTTCCTGGTTCCTCCCCTG
CCTTTCCCGGACATCCCTGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNRRIRIILLAISLLLVIGTLGWLTHVLLVQAEETGHSEQRIRVEALAHEAKLEMDRLLTSFITFEQARGYFEYQPVYAY
KRPYDLRMGAPAPGEATRGSNLAAYLPDYVTAFIQISPAGRVTGPALPPELAGRLNEQKDLYQRLNGKVSSLTSVPSSGN
LWTDIRNEILHESPEPEPTVSGSPAQVETVTSFVPVEDGGNLYILRQVHTSRGIYLQGALMNMDNLNRRLPGQVKMLLPH
SRLATFNPSSPPPEEPRQAGALPFANAPLIFLPGDTGAVPLQDHKKMLTWTLTLIWSMVLLGAAGVIWLMLGTFRLEQRR
GDFVSAVTHELRTPLTSFSLYTEMLEDGMVPEQKKPEYYANMQRECRRLEHLIENVLSYSRLQRNAIRRARDTLTCQELF
EPIAEKIERRLREADISFSFALAQPIRILPIHTDAVSVEQIMDNLTSNAIKYAKGENAKVQLTVQADRHNIVIRFRDNGP
GISPKNRKLVFKPFRRTKDATNSRKPGVGLGLALARDTARSLGGDLKLEFGTLGGASFLLTIPKS

Sequences:

>Translated_545_residues
MNRRIRIILLAISLLLVIGTLGWLTHVLLVQAEETGHSEQRIRVEALAHEAKLEMDRLLTSFITFEQARGYFEYQPVYAY
KRPYDLRMGAPAPGEATRGSNLAAYLPDYVTAFIQISPAGRVTGPALPPELAGRLNEQKDLYQRLNGKVSSLTSVPSSGN
LWTDIRNEILHESPEPEPTVSGSPAQVETVTSFVPVEDGGNLYILRQVHTSRGIYLQGALMNMDNLNRRLPGQVKMLLPH
SRLATFNPSSPPPEEPRQAGALPFANAPLIFLPGDTGAVPLQDHKKMLTWTLTLIWSMVLLGAAGVIWLMLGTFRLEQRR
GDFVSAVTHELRTPLTSFSLYTEMLEDGMVPEQKKPEYYANMQRECRRLEHLIENVLSYSRLQRNAIRRARDTLTCQELF
EPIAEKIERRLREADISFSFALAQPIRILPIHTDAVSVEQIMDNLTSNAIKYAKGENAKVQLTVQADRHNIVIRFRDNGP
GISPKNRKLVFKPFRRTKDATNSRKPGVGLGLALARDTARSLGGDLKLEFGTLGGASFLLTIPKS
>Mature_545_residues
MNRRIRIILLAISLLLVIGTLGWLTHVLLVQAEETGHSEQRIRVEALAHEAKLEMDRLLTSFITFEQARGYFEYQPVYAY
KRPYDLRMGAPAPGEATRGSNLAAYLPDYVTAFIQISPAGRVTGPALPPELAGRLNEQKDLYQRLNGKVSSLTSVPSSGN
LWTDIRNEILHESPEPEPTVSGSPAQVETVTSFVPVEDGGNLYILRQVHTSRGIYLQGALMNMDNLNRRLPGQVKMLLPH
SRLATFNPSSPPPEEPRQAGALPFANAPLIFLPGDTGAVPLQDHKKMLTWTLTLIWSMVLLGAAGVIWLMLGTFRLEQRR
GDFVSAVTHELRTPLTSFSLYTEMLEDGMVPEQKKPEYYANMQRECRRLEHLIENVLSYSRLQRNAIRRARDTLTCQELF
EPIAEKIERRLREADISFSFALAQPIRILPIHTDAVSVEQIMDNLTSNAIKYAKGENAKVQLTVQADRHNIVIRFRDNGP
GISPKNRKLVFKPFRRTKDATNSRKPGVGLGLALARDTARSLGGDLKLEFGTLGGASFLLTIPKS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=30.4932735426009, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=29.6943231441048, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=27.9475982532751, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=28.4, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=25.1101321585903, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=23.9130434782609, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=25.2212389380531, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=22.9074889867841, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=24.4635193133047, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=23.3480176211454, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=26.3392857142857, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=236, Percent_Identity=26.6949152542373, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=213, Percent_Identity=25.8215962441315, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=23.2758620689655, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60918; Mature: 60918

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRIRIILLAISLLLVIGTLGWLTHVLLVQAEETGHSEQRIRVEALAHEAKLEMDRLLT
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SFITFEQARGYFEYQPVYAYKRPYDLRMGAPAPGEATRGSNLAAYLPDYVTAFIQISPAG
HHHHHHHHCCEEEECCEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCC
RVTGPALPPELAGRLNEQKDLYQRLNGKVSSLTSVPSSGNLWTDIRNEILHESPEPEPTV
CCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC
SGSPAQVETVTSFVPVEDGGNLYILRQVHTSRGIYLQGALMNMDNLNRRLPGQVKMLLPH
CCCCCEEEEHHEEEEECCCCCEEEEEEEECCCCEEEEEEEECHHHCCCCCCCCEEEEECC
SRLATFNPSSPPPEEPRQAGALPFANAPLIFLPGDTGAVPLQDHKKMLTWTLTLIWSMVL
CCCEECCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGAAGVIWLMLGTFRLEQRRGDFVSAVTHELRTPLTSFSLYTEMLEDGMVPEQKKPEYYA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHH
NMQRECRRLEHLIENVLSYSRLQRNAIRRARDTLTCQELFEPIAEKIERRLREADISFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ALAQPIRILPIHTDAVSVEQIMDNLTSNAIKYAKGENAKVQLTVQADRHNIVIRFRDNGP
EECCCEEEEEEECCHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEECCCEEEEEECCCCC
GISPKNRKLVFKPFRRTKDATNSRKPGVGLGLALARDTARSLGGDLKLEFGTLGGASFLL
CCCCCCCEEEECCHHHCCCCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCEEEE
TIPKS
ECCCC
>Mature Secondary Structure
MNRRIRIILLAISLLLVIGTLGWLTHVLLVQAEETGHSEQRIRVEALAHEAKLEMDRLLT
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SFITFEQARGYFEYQPVYAYKRPYDLRMGAPAPGEATRGSNLAAYLPDYVTAFIQISPAG
HHHHHHHHCCEEEECCEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCC
RVTGPALPPELAGRLNEQKDLYQRLNGKVSSLTSVPSSGNLWTDIRNEILHESPEPEPTV
CCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC
SGSPAQVETVTSFVPVEDGGNLYILRQVHTSRGIYLQGALMNMDNLNRRLPGQVKMLLPH
CCCCCEEEEHHEEEEECCCCCEEEEEEEECCCCEEEEEEEECHHHCCCCCCCCEEEEECC
SRLATFNPSSPPPEEPRQAGALPFANAPLIFLPGDTGAVPLQDHKKMLTWTLTLIWSMVL
CCCEECCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGAAGVIWLMLGTFRLEQRRGDFVSAVTHELRTPLTSFSLYTEMLEDGMVPEQKKPEYYA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHH
NMQRECRRLEHLIENVLSYSRLQRNAIRRARDTLTCQELFEPIAEKIERRLREADISFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ALAQPIRILPIHTDAVSVEQIMDNLTSNAIKYAKGENAKVQLTVQADRHNIVIRFRDNGP
EECCCEEEEEEECCHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEECCCEEEEEECCCCC
GISPKNRKLVFKPFRRTKDATNSRKPGVGLGLALARDTARSLGGDLKLEFGTLGGASFLL
CCCCCCCEEEECCHHHCCCCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCEEEE
TIPKS
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]