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The map label for this gene is nahA [H]

Identifier: 187736156

GI number: 187736156

Start: 2021876

End: 2023519

Strand: Direct

Name: nahA [H]

Synonym: Amuc_1669

Alternate gene names: 187736156

Gene position: 2021876-2023519 (Clockwise)

Preceding gene: 187736154

Following gene: 187736161

Centisome position: 75.89

GC content: 53.71

Gene sequence:

>1644_bases
ATGATGTTCAGACATGTTTCCCATGTGTTTCTTTTTCTGTTTTCCGGCTTATGCGGCACGGCCGTGAATGCTCAGGATCA
GATAATACCCCGGCCCGTGTCCGTGAAGGTAGAGGCCAAGGGGGCGGCAACGCCCGTGAAGCTGGGTGAAGGAATGCGCA
TTATATGCAAGGAGAAGGACGGGGAGTTCCGGCGCCAGGCTCACTTGTTGCAGCAGTTTTTGTCACGCGGAACCGGATTG
GCTCTGGACGGGGCTGGCGGTACGGGAATAATCCGCGTTGTGAAGGACGCTGCCCTGAAGCAGTACGGGCCGGAGGCATA
CCGTTTGGAAGCGGCTCCCGGAAATATCGTCATCAGCGCCGCGACTCCCAAAGGAGTTTATTATGCGGGGCAAAGTCTGG
CGCAGATGCTGCCTGCCGCCTTTTTCAACAATGATGCGGACAAAAAGAGCGTAAGTTGGAATGTAGCGGAGAAGCCTTTT
TCCATATTGGATTATCCCCGTTTTGCCTGGCGAGCCTTCATGCTGGATGAAGCACGGCATTTTTTTGGAGAGGAGGAGGT
GAAGAGGCTGATTGACCAAATGGGGCTCCTGAAAATGAATGTCCTGCACTGGCATTTGTCGGATGATGCCGGATGGCGCA
TCCAGATTAAAAAATATCCCAAACTGACATCCGTGGGAGGCAAGAGGAGAGATACGGAGATAGAGACGTGGGGAAGCGGC
AAGTATGAAGGCAGGCCCCATGAAGGCTTTTATACGCAGGAACAGGTCAGGCGCATTGTCCGGTATGCGGCCGACAGGAA
TATAACGATTGTTCCTGAAATAGATATTCCGGGCCATTCCGCCGCCGCCATCGTTTCCTATCCGGAGTTGAAATTGTCCG
CCAGGCCTTTCGCGGAAGTGCCCGTGAGTTTCAATGACGGAGCGGCGTTTGATCCCACCAGCGAACGTACCTACCAGTTC
CTGGGAGACATCATGACAGAGCTGGCTTCCCTCTTTCCCGGAGGTATCATTCACATCGGCGGTGACGAGGTGCGGTACAA
AAAGTACTGGGAAGGCGTGCCCCACATTGAGGCGTTCATGAAGAAAAAAGGCATTAAGACTTTTCCCGACCTTCAAATCA
TGTTTACGAATCGGATTTCCGGCATGCTGGCTGGGATGGGGCGCCGGATGATGGGGTGGAATGAAATACTGGGGTCCGAC
GTGCACAATGACGGCGGCCGGGGAGCTGCGCTCGGCAAGCTGGATGCAAATGCTATCATTCATTTCTGGTATGGGTCCGA
TAAAATTGCCGCCAAGGCGATCAGGGAAGGCCGCCAGGTGGTGAATTCCACTTCCCACATGACTTACATTAACAAAGGAT
ATGACAAGCTCCCTCTGTCCAGGTCCTATTCTTTTGAGCCCGTTTTTGCGGGATTGAACCCGGAGCAGCAGAAGAATGTC
ATCGGGCTGGGCTGCCAGGTCTGGACGGAATGGATTGCGGACGTGGAGAAACTGCACCGTCATGTATTTCCCCGTATTGC
CGCTTATGCGGAGACGGGGTGGACCCGGAAGGAGGATAAGAATTTTCAGGATTTCCAGAGGCGTTTGACGGGGTATGAAA
AAATTTTGGATGCCCAGGGCATCCGGCACGGTGAAAAGGAGTAG

Upstream 100 bases:

>100_bases
CGGCACTTCGTGGAGAGGATGTTGCACCCCGGTTTTGACGGGTGGAAGAGAAACTGGGGAGAAAAGGAAAGATTCCTGGG
AAAAACAGTGTATATTGAAC

Downstream 100 bases:

>100_bases
TTGAAAAATTCGCCGCCGGGGATGAAGCGTCCTGGCTGAGTCAACAGTAAACCCGCTTGTTACTTGGTTAAGGATTCGGG
AGAGTTCCTGTCAATGGCTT

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MMFRHVSHVFLFLFSGLCGTAVNAQDQIIPRPVSVKVEAKGAATPVKLGEGMRIICKEKDGEFRRQAHLLQQFLSRGTGL
ALDGAGGTGIIRVVKDAALKQYGPEAYRLEAAPGNIVISAATPKGVYYAGQSLAQMLPAAFFNNDADKKSVSWNVAEKPF
SILDYPRFAWRAFMLDEARHFFGEEEVKRLIDQMGLLKMNVLHWHLSDDAGWRIQIKKYPKLTSVGGKRRDTEIETWGSG
KYEGRPHEGFYTQEQVRRIVRYAADRNITIVPEIDIPGHSAAAIVSYPELKLSARPFAEVPVSFNDGAAFDPTSERTYQF
LGDIMTELASLFPGGIIHIGGDEVRYKKYWEGVPHIEAFMKKKGIKTFPDLQIMFTNRISGMLAGMGRRMMGWNEILGSD
VHNDGGRGAALGKLDANAIIHFWYGSDKIAAKAIREGRQVVNSTSHMTYINKGYDKLPLSRSYSFEPVFAGLNPEQQKNV
IGLGCQVWTEWIADVEKLHRHVFPRIAAYAETGWTRKEDKNFQDFQRRLTGYEKILDAQGIRHGEKE

Sequences:

>Translated_547_residues
MMFRHVSHVFLFLFSGLCGTAVNAQDQIIPRPVSVKVEAKGAATPVKLGEGMRIICKEKDGEFRRQAHLLQQFLSRGTGL
ALDGAGGTGIIRVVKDAALKQYGPEAYRLEAAPGNIVISAATPKGVYYAGQSLAQMLPAAFFNNDADKKSVSWNVAEKPF
SILDYPRFAWRAFMLDEARHFFGEEEVKRLIDQMGLLKMNVLHWHLSDDAGWRIQIKKYPKLTSVGGKRRDTEIETWGSG
KYEGRPHEGFYTQEQVRRIVRYAADRNITIVPEIDIPGHSAAAIVSYPELKLSARPFAEVPVSFNDGAAFDPTSERTYQF
LGDIMTELASLFPGGIIHIGGDEVRYKKYWEGVPHIEAFMKKKGIKTFPDLQIMFTNRISGMLAGMGRRMMGWNEILGSD
VHNDGGRGAALGKLDANAIIHFWYGSDKIAAKAIREGRQVVNSTSHMTYINKGYDKLPLSRSYSFEPVFAGLNPEQQKNV
IGLGCQVWTEWIADVEKLHRHVFPRIAAYAETGWTRKEDKNFQDFQRRLTGYEKILDAQGIRHGEKE
>Mature_547_residues
MMFRHVSHVFLFLFSGLCGTAVNAQDQIIPRPVSVKVEAKGAATPVKLGEGMRIICKEKDGEFRRQAHLLQQFLSRGTGL
ALDGAGGTGIIRVVKDAALKQYGPEAYRLEAAPGNIVISAATPKGVYYAGQSLAQMLPAAFFNNDADKKSVSWNVAEKPF
SILDYPRFAWRAFMLDEARHFFGEEEVKRLIDQMGLLKMNVLHWHLSDDAGWRIQIKKYPKLTSVGGKRRDTEIETWGSG
KYEGRPHEGFYTQEQVRRIVRYAADRNITIVPEIDIPGHSAAAIVSYPELKLSARPFAEVPVSFNDGAAFDPTSERTYQF
LGDIMTELASLFPGGIIHIGGDEVRYKKYWEGVPHIEAFMKKKGIKTFPDLQIMFTNRISGMLAGMGRRMMGWNEILGSD
VHNDGGRGAALGKLDANAIIHFWYGSDKIAAKAIREGRQVVNSTSHMTYINKGYDKLPLSRSYSFEPVFAGLNPEQQKNV
IGLGCQVWTEWIADVEKLHRHVFPRIAAYAETGWTRKEDKNFQDFQRRLTGYEKILDAQGIRHGEKE

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=386, Percent_Identity=27.4611398963731, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI189181666, Length=404, Percent_Identity=26.4851485148515, Blast_Score=146, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17569815, Length=437, Percent_Identity=26.5446224256293, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24657468, Length=458, Percent_Identity=24.0174672489083, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17647501, Length=458, Percent_Identity=24.0174672489083, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281365639, Length=459, Percent_Identity=23.9651416122004, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24657474, Length=459, Percent_Identity=23.9651416122004, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17933586, Length=539, Percent_Identity=24.30426716141, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24653074, Length=414, Percent_Identity=26.0869565217391, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45551090, Length=411, Percent_Identity=26.0340632603406, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 61437; Mature: 61437

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFRHVSHVFLFLFSGLCGTAVNAQDQIIPRPVSVKVEAKGAATPVKLGEGMRIICKEKD
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEECCCCCEEEEECCC
GEFRRQAHLLQQFLSRGTGLALDGAGGTGIIRVVKDAALKQYGPEAYRLEAAPGNIVISA
CHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEE
ATPKGVYYAGQSLAQMLPAAFFNNDADKKSVSWNVAEKPFSILDYPRFAWRAFMLDEARH
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHCCCHHHHHHHHHHHHHH
FFGEEEVKRLIDQMGLLKMNVLHWHLSDDAGWRIQIKKYPKLTSVGGKRRDTEIETWGSG
HCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCC
KYEGRPHEGFYTQEQVRRIVRYAADRNITIVPEIDIPGHSAAAIVSYPELKLSARPFAEV
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCEECCCCHHHC
PVSFNDGAAFDPTSERTYQFLGDIMTELASLFPGGIIHIGGDEVRYKKYWEGVPHIEAFM
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCHHHHHHH
KKKGIKTFPDLQIMFTNRISGMLAGMGRRMMGWNEILGSDVHNDGGRGAALGKLDANAII
HHCCCCCCCCEEEEEHHHHHHHHHHHCHHHCCHHHHHCCCCCCCCCCCCEEEEECCCEEE
HFWYGSDKIAAKAIREGRQVVNSTSHMTYINKGYDKLPLSRSYSFEPVFAGLNPEQQKNV
EEEECCCHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCEEEECCCCHHHCCE
IGLGCQVWTEWIADVEKLHRHVFPRIAAYAETGWTRKEDKNFQDFQRRLTGYEKILDAQG
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
IRHGEKE
CCCCCCC
>Mature Secondary Structure
MMFRHVSHVFLFLFSGLCGTAVNAQDQIIPRPVSVKVEAKGAATPVKLGEGMRIICKEKD
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEECCCCCEEEEECCC
GEFRRQAHLLQQFLSRGTGLALDGAGGTGIIRVVKDAALKQYGPEAYRLEAAPGNIVISA
CHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEE
ATPKGVYYAGQSLAQMLPAAFFNNDADKKSVSWNVAEKPFSILDYPRFAWRAFMLDEARH
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHCCCHHHHHHHHHHHHHH
FFGEEEVKRLIDQMGLLKMNVLHWHLSDDAGWRIQIKKYPKLTSVGGKRRDTEIETWGSG
HCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCC
KYEGRPHEGFYTQEQVRRIVRYAADRNITIVPEIDIPGHSAAAIVSYPELKLSARPFAEV
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCEECCCCHHHC
PVSFNDGAAFDPTSERTYQFLGDIMTELASLFPGGIIHIGGDEVRYKKYWEGVPHIEAFM
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCHHHHHHH
KKKGIKTFPDLQIMFTNRISGMLAGMGRRMMGWNEILGSDVHNDGGRGAALGKLDANAII
HHCCCCCCCCEEEEEHHHHHHHHHHHCHHHCCHHHHHCCCCCCCCCCCCEEEEECCCEEE
HFWYGSDKIAAKAIREGRQVVNSTSHMTYINKGYDKLPLSRSYSFEPVFAGLNPEQQKNV
EEEECCCHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCEEEECCCCHHHCCE
IGLGCQVWTEWIADVEKLHRHVFPRIAAYAETGWTRKEDKNFQDFQRRLTGYEKILDAQG
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
IRHGEKE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]