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The map label for this gene is prc [H]

Identifier: 187736120

GI number: 187736120

Start: 1965361

End: 1967607

Strand: Reverse

Name: prc [H]

Synonym: Amuc_1631

Alternate gene names: 187736120

Gene position: 1967607-1965361 (Counterclockwise)

Preceding gene: 187736132

Following gene: 187736119

Centisome position: 73.86

GC content: 55.14

Gene sequence:

>2247_bases
ATGGAAAAAAACGCACCCTTTTCCGTTATGAACATGCACTCATTCCGTTGGATTAGACTCACCGCATTCTCGGCCCTGGC
CGCAGCCGCCATTACTTCCTGCGCCTCTGCGGCTACGGACTTCAACCAGGTGGGCAAGCAAATGTCCCTGCTGCTCCAGA
ATTTCCACTTCTCCCGCAAAGAATTCAGCGATGAACTATCCACTAAATTCCTGGAAACCTACCTGCGCAAGGTAGACCCC
AACAAAATATTCTTCACCCAGCAGGACGTAGACGCCCTCAAAAGAAAATACGGTAAGGAGCTGGACGACTACCTTATGTC
CGGCCAGATGATGGATGCGGCCCAGGCCATGCACGCCCTTTACCGCCAGCGCGCCATGCAGCGCATCTCCTATGCGCGGG
ATTTGCTGAAAAAGGGAGGCTTCACCTTTGACAAAGACAAGTCTATCGAACGTTCCCGCCGCAAAACAGCCGCGTGGCCC
AAGGATGAGGCGGAAATGCAGCAGGTCTGGAAAGACATGGTGGAGGAACAGCTCCTGTCCGAAATCCTGCGCCGTGAAAC
CGTAGCGCGCCTGGCCAAGGAACAGAACAAGCCCGATCCCCTGGCCAATGAAAAACCCGCGGAGGAAAAACTGCTTATGC
GTTATGAACGCATTCAACGCAATATTCAGGAAACGGATCTGGAAGACGTAGCGGAAACACTGCTCAGCGCCGTAGCCTTG
ACGTATGACCCGCATACGGATTACATGGGTGCGCGCCAGGTGGACCGTTTCAAAATCTCCATGGGTACGGAACTCACCGG
CATCGGCGCCCTGTTGGGCAGTGAAGACGACGGTTCCACCAAAATTACCGGTATCGTTGTGGGAGGACCGGCTGACAAAT
CCGGAGAATTGAAGCTGAACGACCGCATCGTTGCCATTGACTCCGACAACTCCGGAGAAATGGTGGATATCCTGTTCATG
AAGCTGGACAAAGTGGTGGATATGATCCGCGGAGCCGAAAATACCCAGATGCGCCTGAAAGTAGAGCCGGCAGACGCCCC
CGGACAGGCCAAAATCATTACGCTGACCCGCTCCAAGGTACCTCTGAAGGATGAACTTGCCAAAGGTGAAATCATTGAAC
TTACCGGAGCTCCGGAAGGCAGGAACCGCATTGGCGTGCTGAGCCTTCCCTCCTTCTACGCAGACATGGAAGGCGGAGAC
CGCCGCTGTGCCAAGGATGTCAAAAAAATCCTGGAACGGATGAACAAGGAAAATGTGGATGGCCTGGTAATTGACCTGCG
TAGCAACGGCGGCGGTTCCCTGGAGGAAGTGCGCCTGATGACGGGCTTCTTTACCGGAAACGGCCCCGTGGTACAAATCA
AGGACACCCGCGGCAACGTGGATATCAAATCCGCCCACAACCGCCAGAAACTCTTCAATGGCCCCATTGTGGTGCTCATT
AATAAACTCAGCGCATCCGCCTCTGAAATTCTGGCCGCGGCCCTTCAGGATTACGGCCGCGCCGTGATTGTGGGGGATGA
ATCCACCTTCGGGAAGGGGTCTGTGCAGCAGCCTGTGGACATCGGCCAATACCTGCCTTTCTTCGCGGCCAGAGACCGTG
CGGGCCTGCTGAAAGTCACTACCCAGAAATTTTACCGTGTGGCGGGCGGCTCCACCCAGCTCAAAGGCGTGGAAAGCGAT
ATCCAGCTTCCCACCGCTACGGCGGCATTCGAGCTGGGAGAAGACATTCTGGACTACGCGATGCCCTATGACCAGATTAC
GCCCTGCACCAACTACAAAAAGGACTCCTCCATCGCGGCCATGCTGCCCGTGCTGAAAGATGCCAGCGCGAAGCGCGTGG
AAAAAGACCGCGACCTCCAGATTGCCAGGGAAGATATCGCCATGATGAAACAGCGCATCAAGGACAACAAGCTTTCCCTG
AACAAGAAAATCCGGGAACAGGAAAACTCCGCCCTGGAAGAACGCCGCAAATCCATCAACAAGGAACGTAAAATCCGCTT
CGCGGAAATGGCCAGGGAAGACGCAACCAAATACAAAATTTACCGCCTGACGCTGGATGACGTCAACGCCAAGGAGCTGC
CCCTGGCGGATCCGGAAAAAGACAATGAACAATTCATGCACCTGGCGGAAGACCCCACGGCAGAACTGGACGACTCCCCG
GAATACCCCTCCGGCCTTGATCCGGAACTCCGCGAAGGCATCAACATCGTCCAGGATATGCTGAAGCTGGAATCCTCCGG
AAAATAA

Upstream 100 bases:

>100_bases
AAACAAGGAGAGCAAAATAGCGTCATGTGGACGTTTTATAAGATAGACAATCACCTGCAAATCAGTAACACTTACATCCC
GGCGCCAGCTTTTTCCCCAA

Downstream 100 bases:

>100_bases
CGGCTCGCTCCTCGCGAACCTCCTTGCCGCCCCGGTCCCATTCAGGGAACCGGGGTTCTTTTTTCCGAGGCAATTCCGGG
AGCCGTGCCTCCCGAACAGC

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 748; Mature: 748

Protein sequence:

>748_residues
MEKNAPFSVMNMHSFRWIRLTAFSALAAAAITSCASAATDFNQVGKQMSLLLQNFHFSRKEFSDELSTKFLETYLRKVDP
NKIFFTQQDVDALKRKYGKELDDYLMSGQMMDAAQAMHALYRQRAMQRISYARDLLKKGGFTFDKDKSIERSRRKTAAWP
KDEAEMQQVWKDMVEEQLLSEILRRETVARLAKEQNKPDPLANEKPAEEKLLMRYERIQRNIQETDLEDVAETLLSAVAL
TYDPHTDYMGARQVDRFKISMGTELTGIGALLGSEDDGSTKITGIVVGGPADKSGELKLNDRIVAIDSDNSGEMVDILFM
KLDKVVDMIRGAENTQMRLKVEPADAPGQAKIITLTRSKVPLKDELAKGEIIELTGAPEGRNRIGVLSLPSFYADMEGGD
RRCAKDVKKILERMNKENVDGLVIDLRSNGGGSLEEVRLMTGFFTGNGPVVQIKDTRGNVDIKSAHNRQKLFNGPIVVLI
NKLSASASEILAAALQDYGRAVIVGDESTFGKGSVQQPVDIGQYLPFFAARDRAGLLKVTTQKFYRVAGGSTQLKGVESD
IQLPTATAAFELGEDILDYAMPYDQITPCTNYKKDSSIAAMLPVLKDASAKRVEKDRDLQIAREDIAMMKQRIKDNKLSL
NKKIREQENSALEERRKSINKERKIRFAEMAREDATKYKIYRLTLDDVNAKELPLADPEKDNEQFMHLAEDPTAELDDSP
EYPSGLDPELREGINIVQDMLKLESSGK

Sequences:

>Translated_748_residues
MEKNAPFSVMNMHSFRWIRLTAFSALAAAAITSCASAATDFNQVGKQMSLLLQNFHFSRKEFSDELSTKFLETYLRKVDP
NKIFFTQQDVDALKRKYGKELDDYLMSGQMMDAAQAMHALYRQRAMQRISYARDLLKKGGFTFDKDKSIERSRRKTAAWP
KDEAEMQQVWKDMVEEQLLSEILRRETVARLAKEQNKPDPLANEKPAEEKLLMRYERIQRNIQETDLEDVAETLLSAVAL
TYDPHTDYMGARQVDRFKISMGTELTGIGALLGSEDDGSTKITGIVVGGPADKSGELKLNDRIVAIDSDNSGEMVDILFM
KLDKVVDMIRGAENTQMRLKVEPADAPGQAKIITLTRSKVPLKDELAKGEIIELTGAPEGRNRIGVLSLPSFYADMEGGD
RRCAKDVKKILERMNKENVDGLVIDLRSNGGGSLEEVRLMTGFFTGNGPVVQIKDTRGNVDIKSAHNRQKLFNGPIVVLI
NKLSASASEILAAALQDYGRAVIVGDESTFGKGSVQQPVDIGQYLPFFAARDRAGLLKVTTQKFYRVAGGSTQLKGVESD
IQLPTATAAFELGEDILDYAMPYDQITPCTNYKKDSSIAAMLPVLKDASAKRVEKDRDLQIAREDIAMMKQRIKDNKLSL
NKKIREQENSALEERRKSINKERKIRFAEMAREDATKYKIYRLTLDDVNAKELPLADPEKDNEQFMHLAEDPTAELDDSP
EYPSGLDPELREGINIVQDMLKLESSGK
>Mature_748_residues
MEKNAPFSVMNMHSFRWIRLTAFSALAAAAITSCASAATDFNQVGKQMSLLLQNFHFSRKEFSDELSTKFLETYLRKVDP
NKIFFTQQDVDALKRKYGKELDDYLMSGQMMDAAQAMHALYRQRAMQRISYARDLLKKGGFTFDKDKSIERSRRKTAAWP
KDEAEMQQVWKDMVEEQLLSEILRRETVARLAKEQNKPDPLANEKPAEEKLLMRYERIQRNIQETDLEDVAETLLSAVAL
TYDPHTDYMGARQVDRFKISMGTELTGIGALLGSEDDGSTKITGIVVGGPADKSGELKLNDRIVAIDSDNSGEMVDILFM
KLDKVVDMIRGAENTQMRLKVEPADAPGQAKIITLTRSKVPLKDELAKGEIIELTGAPEGRNRIGVLSLPSFYADMEGGD
RRCAKDVKKILERMNKENVDGLVIDLRSNGGGSLEEVRLMTGFFTGNGPVVQIKDTRGNVDIKSAHNRQKLFNGPIVVLI
NKLSASASEILAAALQDYGRAVIVGDESTFGKGSVQQPVDIGQYLPFFAARDRAGLLKVTTQKFYRVAGGSTQLKGVESD
IQLPTATAAFELGEDILDYAMPYDQITPCTNYKKDSSIAAMLPVLKDASAKRVEKDRDLQIAREDIAMMKQRIKDNKLSL
NKKIREQENSALEERRKSINKERKIRFAEMAREDATKYKIYRLTLDDVNAKELPLADPEKDNEQFMHLAEDPTAELDDSP
EYPSGLDPELREGINIVQDMLKLESSGK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=757, Percent_Identity=33.6856010568032, Blast_Score=352, Evalue=6e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 83862; Mature: 83862

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNAPFSVMNMHSFRWIRLTAFSALAAAAITSCASAATDFNQVGKQMSLLLQNFHFSRK
CCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
EFSDELSTKFLETYLRKVDPNKIFFTQQDVDALKRKYGKELDDYLMSGQMMDAAQAMHAL
HHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
YRQRAMQRISYARDLLKKGGFTFDKDKSIERSRRKTAAWPKDEAEMQQVWKDMVEEQLLS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
EILRRETVARLAKEQNKPDPLANEKPAEEKLLMRYERIQRNIQETDLEDVAETLLSAVAL
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TYDPHTDYMGARQVDRFKISMGTELTGIGALLGSEDDGSTKITGIVVGGPADKSGELKLN
CCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEC
DRIVAIDSDNSGEMVDILFMKLDKVVDMIRGAENTQMRLKVEPADAPGQAKIITLTRSKV
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCC
PLKDELAKGEIIELTGAPEGRNRIGVLSLPSFYADMEGGDRRCAKDVKKILERMNKENVD
CCHHHHCCCCEEEEECCCCCCCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
GLVIDLRSNGGGSLEEVRLMTGFFTGNGPVVQIKDTRGNVDIKSAHNRQKLFNGPIVVLI
EEEEEEECCCCCCHHHHHEEHEEEECCCCEEEEECCCCCEEECCCCCHHHHHCCCEEEEE
NKLSASASEILAAALQDYGRAVIVGDESTFGKGSVQQPVDIGQYLPFFAARDRAGLLKVT
EHHCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHCCHHHCCCCCCCEEHH
TQKFYRVAGGSTQLKGVESDIQLPTATAAFELGEDILDYAMPYDQITPCTNYKKDSSIAA
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHH
MLPVLKDASAKRVEKDRDLQIAREDIAMMKQRIKDNKLSLNKKIREQENSALEERRKSIN
HHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
KERKIRFAEMAREDATKYKIYRLTLDDVNAKELPLADPEKDNEQFMHLAEDPTAELDDSP
HHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCC
EYPSGLDPELREGINIVQDMLKLESSGK
CCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKNAPFSVMNMHSFRWIRLTAFSALAAAAITSCASAATDFNQVGKQMSLLLQNFHFSRK
CCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
EFSDELSTKFLETYLRKVDPNKIFFTQQDVDALKRKYGKELDDYLMSGQMMDAAQAMHAL
HHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
YRQRAMQRISYARDLLKKGGFTFDKDKSIERSRRKTAAWPKDEAEMQQVWKDMVEEQLLS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
EILRRETVARLAKEQNKPDPLANEKPAEEKLLMRYERIQRNIQETDLEDVAETLLSAVAL
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TYDPHTDYMGARQVDRFKISMGTELTGIGALLGSEDDGSTKITGIVVGGPADKSGELKLN
CCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEC
DRIVAIDSDNSGEMVDILFMKLDKVVDMIRGAENTQMRLKVEPADAPGQAKIITLTRSKV
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCC
PLKDELAKGEIIELTGAPEGRNRIGVLSLPSFYADMEGGDRRCAKDVKKILERMNKENVD
CCHHHHCCCCEEEEECCCCCCCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
GLVIDLRSNGGGSLEEVRLMTGFFTGNGPVVQIKDTRGNVDIKSAHNRQKLFNGPIVVLI
EEEEEEECCCCCCHHHHHEEHEEEECCCCEEEEECCCCCEEECCCCCHHHHHCCCEEEEE
NKLSASASEILAAALQDYGRAVIVGDESTFGKGSVQQPVDIGQYLPFFAARDRAGLLKVT
EHHCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHCCHHHCCCCCCCEEHH
TQKFYRVAGGSTQLKGVESDIQLPTATAAFELGEDILDYAMPYDQITPCTNYKKDSSIAA
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHH
MLPVLKDASAKRVEKDRDLQIAREDIAMMKQRIKDNKLSLNKKIREQENSALEERRKSIN
HHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
KERKIRFAEMAREDATKYKIYRLTLDDVNAKELPLADPEKDNEQFMHLAEDPTAELDDSP
HHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCC
EYPSGLDPELREGINIVQDMLKLESSGK
CCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]