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The map label for this gene is dnaC [H]

Identifier: 187735870

GI number: 187735870

Start: 1641031

End: 1642344

Strand: Direct

Name: dnaC [H]

Synonym: Amuc_1377

Alternate gene names: 187735870

Gene position: 1641031-1642344 (Clockwise)

Preceding gene: 187735869

Following gene: 187735876

Centisome position: 61.6

GC content: 56.7

Gene sequence:

>1314_bases
ATGCATTTTACAGAAACACAACTCAACGCCGAAAAGACCGTTCTTGGCAACTGCATTGACGGCGCCGACAAGGTAGCCGC
CCTGATCGAGCAAGGTTTCACGAAGGCTCATTTTGTCCTTCTGGCCCATCAGAAGGTCTGGAGCGCCTTTGAGACTCTGG
CCAAGACTCCAGAAAAGGTCAATATCACCGACCTGATCCAGCACCTGGAAGCCGCCGGCGAGCTTGAATCCGTAGGAGGT
CACGCCGGGCTTGTCGAGCTTTCAACCAGCTTTGCCTACCATTTCCAGTTCGAGCCCTCCGTGAAGATTCTGGTGGAAGC
CAAGAAGAAGCGGGATGTGGAATCCCTGTTCATTTCCGGGCTGGAAAATCTTCAAAACCCAACCCTGAGCAAAGACGAAG
TGCTGGCGGAAGCCGAAAAGGTGATGTCCTCCTTACGGGAAAGTTACGGAGTGGCCCAAGTGGCGCGTATGGCTGATGGC
ACACAGAAGGTGGTGGAAGGGTTGGAGTTTCGCATCAAGAATCCAGGACAGACCAAGGGGCTTCCTACCGGCTACCCCTC
CCTGGACAGGATGCTGGACGGCTTACAGAACACGGCTATGGTGGTCATCGGAGCCCGGCCGGCCGTGGGGAAGACTTCCT
TCATGACCAACATTCTGTACAATCTGGCCGCCGAAGGGGTGCCAGTAGGCATGTTCTCCCTGGAAATGTCCAAGGAGCAG
TTGCTTGAACGCACGCTTTTTGGCATGTCCAAAATCAATGCGGCCAATCTGCGCCGAGGCATCAAGCTGACCAAGTGGCA
GCAGGATGCTTTCACCAACGCGGTTCGCAAGGTAAGGAGCCTGCCTTTCTTCGTGGACGACCGGGGCGCCTTGAGGATTG
ACCAGATCCAGGCGACCGCCCGGCGCATGGTGGCGGACCACGGCGTGAGGTGCATCGGCGTGGATTACCTGCAGCTTGCC
AATCCTACCGGACGCCAGGCGTCCCGGGAACGGGAGGTGTCGGAGATTTCCGCCGGCCTCAAAGCCCTGGCCAAGGAACT
GAATATTCCGGTGATCGTGTTGGCCCAGTTGAACCGGGAAGCGGAGAAACGCGCCGGGAAGGAAGCCGGGGTTCCCCGTG
TGTCCGATTTGAGGGATTCAGGGTCTATCGAACAGGACGCTGATCAGATATTGTTGCTCTACAGGCCTTACGTCATGGAC
AAAAACGCAGATCCGGCAGAGGCGAAAATCATCGTCGGCAAGAACCGCTTCGGGGAGATTGGTTACATTGACCTGAAATG
GGACGCTGCCGCCACGACTTACAGGGAGGTTTAA

Upstream 100 bases:

>100_bases
AAGAAATCTTGATGCCAAAGGGCAACTACCCGGAGAGGAAAGCGACCCCTTCGATCCAAAATTTAGAAAAAATATTTAAC
CCTCAAAAAGAGAAACCATC

Downstream 100 bases:

>100_bases
AACATGATATCACTATTTAAGGTAGTGCTACAATTTGGGAAGCTTTTCAAGGGCTTGTGTAAACTCCTTGGCTCCAAAGT
CGATGTATCCTTCATGGACT

Product: DnaB domain protein helicase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MHFTETQLNAEKTVLGNCIDGADKVAALIEQGFTKAHFVLLAHQKVWSAFETLAKTPEKVNITDLIQHLEAAGELESVGG
HAGLVELSTSFAYHFQFEPSVKILVEAKKKRDVESLFISGLENLQNPTLSKDEVLAEAEKVMSSLRESYGVAQVARMADG
TQKVVEGLEFRIKNPGQTKGLPTGYPSLDRMLDGLQNTAMVVIGARPAVGKTSFMTNILYNLAAEGVPVGMFSLEMSKEQ
LLERTLFGMSKINAANLRRGIKLTKWQQDAFTNAVRKVRSLPFFVDDRGALRIDQIQATARRMVADHGVRCIGVDYLQLA
NPTGRQASREREVSEISAGLKALAKELNIPVIVLAQLNREAEKRAGKEAGVPRVSDLRDSGSIEQDADQILLLYRPYVMD
KNADPAEAKIIVGKNRFGEIGYIDLKWDAAATTYREV

Sequences:

>Translated_437_residues
MHFTETQLNAEKTVLGNCIDGADKVAALIEQGFTKAHFVLLAHQKVWSAFETLAKTPEKVNITDLIQHLEAAGELESVGG
HAGLVELSTSFAYHFQFEPSVKILVEAKKKRDVESLFISGLENLQNPTLSKDEVLAEAEKVMSSLRESYGVAQVARMADG
TQKVVEGLEFRIKNPGQTKGLPTGYPSLDRMLDGLQNTAMVVIGARPAVGKTSFMTNILYNLAAEGVPVGMFSLEMSKEQ
LLERTLFGMSKINAANLRRGIKLTKWQQDAFTNAVRKVRSLPFFVDDRGALRIDQIQATARRMVADHGVRCIGVDYLQLA
NPTGRQASREREVSEISAGLKALAKELNIPVIVLAQLNREAEKRAGKEAGVPRVSDLRDSGSIEQDADQILLLYRPYVMD
KNADPAEAKIIVGKNRFGEIGYIDLKWDAAATTYREV
>Mature_437_residues
MHFTETQLNAEKTVLGNCIDGADKVAALIEQGFTKAHFVLLAHQKVWSAFETLAKTPEKVNITDLIQHLEAAGELESVGG
HAGLVELSTSFAYHFQFEPSVKILVEAKKKRDVESLFISGLENLQNPTLSKDEVLAEAEKVMSSLRESYGVAQVARMADG
TQKVVEGLEFRIKNPGQTKGLPTGYPSLDRMLDGLQNTAMVVIGARPAVGKTSFMTNILYNLAAEGVPVGMFSLEMSKEQ
LLERTLFGMSKINAANLRRGIKLTKWQQDAFTNAVRKVRSLPFFVDDRGALRIDQIQATARRMVADHGVRCIGVDYLQLA
NPTGRQASREREVSEISAGLKALAKELNIPVIVLAQLNREAEKRAGKEAGVPRVSDLRDSGSIEQDADQILLLYRPYVMD
KNADPAEAKIIVGKNRFGEIGYIDLKWDAAATTYREV

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=437, Percent_Identity=33.4096109839817, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48130; Mature: 48130

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFTETQLNAEKTVLGNCIDGADKVAALIEQGFTKAHFVLLAHQKVWSAFETLAKTPEKV
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHEEEHHHHHHHHHHHHHCCCCCC
NITDLIQHLEAAGELESVGGHAGLVELSTSFAYHFQFEPSVKILVEAKKKRDVESLFISG
CHHHHHHHHHHHCCHHHCCCCCCEEEEECCEEEEEEECCCEEEEEEEHHHCCHHHHHHHH
LENLQNPTLSKDEVLAEAEKVMSSLRESYGVAQVARMADGTQKVVEGLEFRIKNPGQTKG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCC
LPTGYPSLDRMLDGLQNTAMVVIGARPAVGKTSFMTNILYNLAAEGVPVGMFSLEMSKEQ
CCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
LLERTLFGMSKINAANLRRGIKLTKWQQDAFTNAVRKVRSLPFFVDDRGALRIDQIQATA
HHHHHHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCEECCCCCEEHHHHHHHH
RRMVADHGVRCIGVDYLQLANPTGRQASREREVSEISAGLKALAKELNIPVIVLAQLNRE
HHHHHHCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHH
AEKRAGKEAGVPRVSDLRDSGSIEQDADQILLLYRPYVMDKNADPAEAKIIVGKNRFGEI
HHHHCCHHCCCCCHHHCCCCCCCCCCHHHEEEEECCEEECCCCCCCCEEEEEECCCCCCE
GYIDLKWDAAATTYREV
EEEEEEECCCCHHHHCC
>Mature Secondary Structure
MHFTETQLNAEKTVLGNCIDGADKVAALIEQGFTKAHFVLLAHQKVWSAFETLAKTPEKV
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHEEEHHHHHHHHHHHHHCCCCCC
NITDLIQHLEAAGELESVGGHAGLVELSTSFAYHFQFEPSVKILVEAKKKRDVESLFISG
CHHHHHHHHHHHCCHHHCCCCCCEEEEECCEEEEEEECCCEEEEEEEHHHCCHHHHHHHH
LENLQNPTLSKDEVLAEAEKVMSSLRESYGVAQVARMADGTQKVVEGLEFRIKNPGQTKG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCC
LPTGYPSLDRMLDGLQNTAMVVIGARPAVGKTSFMTNILYNLAAEGVPVGMFSLEMSKEQ
CCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
LLERTLFGMSKINAANLRRGIKLTKWQQDAFTNAVRKVRSLPFFVDDRGALRIDQIQATA
HHHHHHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCEECCCCCEEHHHHHHHH
RRMVADHGVRCIGVDYLQLANPTGRQASREREVSEISAGLKALAKELNIPVIVLAQLNRE
HHHHHHCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHH
AEKRAGKEAGVPRVSDLRDSGSIEQDADQILLLYRPYVMDKNADPAEAKIIVGKNRFGEI
HHHHCCHHCCCCCHHHCCCCCCCCCCHHHEEEEECCEEECCCCCCCCEEEEEECCCCCCE
GYIDLKWDAAATTYREV
EEEEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]