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The map label for this gene is sdaA [H]

Identifier: 187735762

GI number: 187735762

Start: 1528758

End: 1530137

Strand: Reverse

Name: sdaA [H]

Synonym: Amuc_1268

Alternate gene names: 187735762

Gene position: 1530137-1528758 (Counterclockwise)

Preceding gene: 187735763

Following gene: 187735761

Centisome position: 57.44

GC content: 60.0

Gene sequence:

>1380_bases
ATGCACCATTACAGCATTTTTGAGCTTTTCAGCATCGGCATAGGTCCTTCATCATCCCATACCGTAGGGCCCATGCGGGC
GGCGCACCGCTTTCTTGAACAGATGCGCCACTCCCCGCGCTTGGCGGAAATCTCAGGCATCCGCTGCGAATGCTACGGCT
CCCTGGCCGCCACCGGACATGGGCACGGCACAGACACAGCCATCATGCTGGGGCTTCTGGGGGAAGAACCCCATACGGTG
GAGCCGCGCAGCATTCCCGGAAAAATCGCCCGCCTGCACCAGCAGGAAACGTTGTCCGTCACGGAAGAAAAAAACGTCCG
CTTCTCTCCTTCCCGCGACCTGGATCTTTCCCACTACCAGCCCCTGCGCCTGCATCCGAACGGGATGCAGTTTACTGCCG
TCAACCAGGACGGAGACCCGGTGGAAGACGCGGTATTTTATTCCACGGGGGGCGGGTTCGTCTCTTCCGAACAGGAACTT
CTGCATCCGGAAGAAAGGGATCGGGAAACCTTCCCTTTTCCTTATGAATCCGCGGAGGAACTGCTGCACATGGCTGATGA
GCGTGGATGCCCTCTTTCCTCCATTGTCATGGCAAACGAATGCGCCATGCTCCCGGAACGGGAAGTCCGTGAAAAACTGG
ACCTGATCTGGGCGACGATGAAGCAGTCCATCTCCAACGGCATGAGCGCGCGCGGCAACCTGCCGGGCGTTCTGCAGGTT
CCGCGCCGGGCCAAAACTTTGCGCAAGAATCTTCTGGTGCACGGAGAATCGGCCTTGAAAGACCCTCTCTCCATTATGGA
CTGGATCAATCTGTACGCCATTGCCGTAAGTGAGGAAAACGCGGCCGGCGGCCGCATCGTCACCGCTCCGACCAATGGAG
CGGCGGGAATCGTTCCGGCCGTTCTTAACTACGCCACCAAATTCTGCGTTTCCCCGTATCCGGATGCCGTGCATCGCTTC
CTGCTCACCGCCGGGGGAATCGCCATCCTGTACAAGAAAAACGCCTCCATTTCCGGCGCGGACGTAGGCTGCCAGGGAGA
AGTGGGAGTAGCCTGCTCCATGGCCGCCGCCGCTCTTGCGGAGTACCTGGGGGGAACACCCCACCAGGTGGAAAACGCCG
CGGAAATAGGCATGGAGCACAATCTGGGCCTCACCTGCGATCCTATTGCGGGCCTCGTCCAGATACCCTGCATTGAGCGC
AACGCCATCGCCGCCATCAAGGCCATCAACGCCGCCCGCATGGCCCTGGGCGGCACGGGCGCTCATTTTGTCCCGCTGGA
CAAGGTCATCCGCACCATGCTGGACACCGGAAGGGACATGCAATCCAAATACAAGGAGACCGCCCAGGGCGGCTTGGCCG
TCAACGTGGTGAATTGCTGA

Upstream 100 bases:

>100_bases
GAAGCGGAACGCTACCTGCTGGGGCTGTAAACCCATCTTTCGGAACGGGCCGGAATTCCCAGCGGGATTTCCGGCCCTTC
CCCGCTACAGGAAAACGGAC

Downstream 100 bases:

>100_bases
GGGGACATGAAAACCCTCCCTTGTCTTTTCACGCGCGTCTGTTCCCGCAAAAAACGCTCCGCCGGATTGACAGATACGGG
GAGCAAAGGTAGGGTGCGGG

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MHHYSIFELFSIGIGPSSSHTVGPMRAAHRFLEQMRHSPRLAEISGIRCECYGSLAATGHGHGTDTAIMLGLLGEEPHTV
EPRSIPGKIARLHQQETLSVTEEKNVRFSPSRDLDLSHYQPLRLHPNGMQFTAVNQDGDPVEDAVFYSTGGGFVSSEQEL
LHPEERDRETFPFPYESAEELLHMADERGCPLSSIVMANECAMLPEREVREKLDLIWATMKQSISNGMSARGNLPGVLQV
PRRAKTLRKNLLVHGESALKDPLSIMDWINLYAIAVSEENAAGGRIVTAPTNGAAGIVPAVLNYATKFCVSPYPDAVHRF
LLTAGGIAILYKKNASISGADVGCQGEVGVACSMAAAALAEYLGGTPHQVENAAEIGMEHNLGLTCDPIAGLVQIPCIER
NAIAAIKAINAARMALGGTGAHFVPLDKVIRTMLDTGRDMQSKYKETAQGGLAVNVVNC

Sequences:

>Translated_459_residues
MHHYSIFELFSIGIGPSSSHTVGPMRAAHRFLEQMRHSPRLAEISGIRCECYGSLAATGHGHGTDTAIMLGLLGEEPHTV
EPRSIPGKIARLHQQETLSVTEEKNVRFSPSRDLDLSHYQPLRLHPNGMQFTAVNQDGDPVEDAVFYSTGGGFVSSEQEL
LHPEERDRETFPFPYESAEELLHMADERGCPLSSIVMANECAMLPEREVREKLDLIWATMKQSISNGMSARGNLPGVLQV
PRRAKTLRKNLLVHGESALKDPLSIMDWINLYAIAVSEENAAGGRIVTAPTNGAAGIVPAVLNYATKFCVSPYPDAVHRF
LLTAGGIAILYKKNASISGADVGCQGEVGVACSMAAAALAEYLGGTPHQVENAAEIGMEHNLGLTCDPIAGLVQIPCIER
NAIAAIKAINAARMALGGTGAHFVPLDKVIRTMLDTGRDMQSKYKETAQGGLAVNVVNC
>Mature_459_residues
MHHYSIFELFSIGIGPSSSHTVGPMRAAHRFLEQMRHSPRLAEISGIRCECYGSLAATGHGHGTDTAIMLGLLGEEPHTV
EPRSIPGKIARLHQQETLSVTEEKNVRFSPSRDLDLSHYQPLRLHPNGMQFTAVNQDGDPVEDAVFYSTGGGFVSSEQEL
LHPEERDRETFPFPYESAEELLHMADERGCPLSSIVMANECAMLPEREVREKLDLIWATMKQSISNGMSARGNLPGVLQV
PRRAKTLRKNLLVHGESALKDPLSIMDWINLYAIAVSEENAAGGRIVTAPTNGAAGIVPAVLNYATKFCVSPYPDAVHRF
LLTAGGIAILYKKNASISGADVGCQGEVGVACSMAAAALAEYLGGTPHQVENAAEIGMEHNLGLTCDPIAGLVQIPCIER
NAIAAIKAINAARMALGGTGAHFVPLDKVIRTMLDTGRDMQSKYKETAQGGLAVNVVNC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=452, Percent_Identity=53.0973451327434, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1789161, Length=456, Percent_Identity=51.0964912280702, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI48994925, Length=455, Percent_Identity=51.6483516483517, Blast_Score=437, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49439; Mature: 49439

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHYSIFELFSIGIGPSSSHTVGPMRAAHRFLEQMRHSPRLAEISGIRCECYGSLAATGH
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEHHCCCEEEEECCEEECCC
GHGTDTAIMLGLLGEEPHTVEPRSIPGKIARLHQQETLSVTEEKNVRFSPSRDLDLSHYQ
CCCCCHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
PLRLHPNGMQFTAVNQDGDPVEDAVFYSTGGGFVSSEQELLHPEERDRETFPFPYESAEE
CEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHH
LLHMADERGCPLSSIVMANECAMLPEREVREKLDLIWATMKQSISNGMSARGNLPGVLQV
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
PRRAKTLRKNLLVHGESALKDPLSIMDWINLYAIAVSEENAAGGRIVTAPTNGAAGIVPA
CHHHHHHHHHHEECCCHHHHCHHHHHHHHHEEEEEEECCCCCCCEEEECCCCCCCHHHHH
VLNYATKFCVSPYPDAVHRFLLTAGGIAILYKKNASISGADVGCQGEVGVACSMAAAALA
HHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
EYLGGTPHQVENAAEIGMEHNLGLTCDPIAGLVQIPCIERNAIAAIKAINAARMALGGTG
HHHCCCCHHHHHHHHHCCCCCCCCEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCC
AHFVPLDKVIRTMLDTGRDMQSKYKETAQGGLAVNVVNC
CCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MHHYSIFELFSIGIGPSSSHTVGPMRAAHRFLEQMRHSPRLAEISGIRCECYGSLAATGH
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEHHCCCEEEEECCEEECCC
GHGTDTAIMLGLLGEEPHTVEPRSIPGKIARLHQQETLSVTEEKNVRFSPSRDLDLSHYQ
CCCCCHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
PLRLHPNGMQFTAVNQDGDPVEDAVFYSTGGGFVSSEQELLHPEERDRETFPFPYESAEE
CEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHH
LLHMADERGCPLSSIVMANECAMLPEREVREKLDLIWATMKQSISNGMSARGNLPGVLQV
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
PRRAKTLRKNLLVHGESALKDPLSIMDWINLYAIAVSEENAAGGRIVTAPTNGAAGIVPA
CHHHHHHHHHHEECCCHHHHCHHHHHHHHHEEEEEEECCCCCCCEEEECCCCCCCHHHHH
VLNYATKFCVSPYPDAVHRFLLTAGGIAILYKKNASISGADVGCQGEVGVACSMAAAALA
HHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
EYLGGTPHQVENAAEIGMEHNLGLTCDPIAGLVQIPCIERNAIAAIKAINAARMALGGTG
HHHCCCCHHHHHHHHHCCCCCCCCEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCC
AHFVPLDKVIRTMLDTGRDMQSKYKETAQGGLAVNVVNC
CCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]