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The map label for this gene is rlmH

Identifier: 187735730

GI number: 187735730

Start: 1484306

End: 1484743

Strand: Reverse

Name: rlmH

Synonym: Amuc_1236

Alternate gene names: 187735730

Gene position: 1484743-1484306 (Counterclockwise)

Preceding gene: 187735731

Following gene: 187735727

Centisome position: 55.73

GC content: 55.94

Gene sequence:

>438_bases
ATGCAATTCCTGATTCTGGCCGCCGGAAAGCCTTCCCTAGGCTACGCCAAGGAAGGCGTGGAACTCTATCTCAACCGCCT
CAGGCCCTTCGGCAAGACGGAACTCAAGCTTGTCAGGGACGGAAGCTCCCAAGACGTTTCTAAACGTCTGCTGGCCGCCA
GCGAGGGTTGCCTGCGCATCGCCATGGACGAACGCGGAGAACTTTGGACCACAAGAAAGCTAGTCGACCTGGCAAAGGAC
TGGCAAATGCATTCCGTACGCCGCATCGCGTTTCTCATCGGAGCCTCAGACGGTCATACGGAAGAACTGCGGTCCCGGTG
CAACCATATCCTGTCCTTGAGCAAATTCACCCTTCAACATGAACTGGCGCTTGTTGTCCTGCTGGAACAGCTTTACCGCT
GCCACACTATCCTGGCAGGAACACCATACCATCGGTAA

Upstream 100 bases:

>100_bases
GGCGGACCCGGCTTCTATCGCCGCCATCCGCGGCATTTCGGAAACTTGGGCCCGCACCCTGCTGAACTACCTTAACTCAT
CTTCCAACTCCTGACTTCTC

Downstream 100 bases:

>100_bases
CCCCCGTCAACCAACCATTCCTGCACTGGGAAACCTCCCCCCCTTCACAGCAAATGCAGGAAAATCATTGAAAGCTGCCG
TAAGCAACCTAACCAGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MQFLILAAGKPSLGYAKEGVELYLNRLRPFGKTELKLVRDGSSQDVSKRLLAASEGCLRIAMDERGELWTTRKLVDLAKD
WQMHSVRRIAFLIGASDGHTEELRSRCNHILSLSKFTLQHELALVVLLEQLYRCHTILAGTPYHR

Sequences:

>Translated_145_residues
MQFLILAAGKPSLGYAKEGVELYLNRLRPFGKTELKLVRDGSSQDVSKRLLAASEGCLRIAMDERGELWTTRKLVDLAKD
WQMHSVRRIAFLIGASDGHTEELRSRCNHILSLSKFTLQHELALVVLLEQLYRCHTILAGTPYHR
>Mature_145_residues
MQFLILAAGKPSLGYAKEGVELYLNRLRPFGKTELKLVRDGSSQDVSKRLLAASEGCLRIAMDERGELWTTRKLVDLAKD
WQMHSVRRIAFLIGASDGHTEELRSRCNHILSLSKFTLQHELALVVLLEQLYRCHTILAGTPYHR

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=155, Percent_Identity=27.741935483871, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_AKKM8 (B2URH6)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001877842.1
- ProteinModelPortal:   B2URH6
- SMR:   B2URH6
- GeneID:   6274707
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1236
- HOGENOM:   HBG622807
- OMA:   NIANDCL
- ProtClustDB:   CLSK738928
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 16488; Mature: 16488

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLILAAGKPSLGYAKEGVELYLNRLRPFGKTELKLVRDGSSQDVSKRLLAASEGCLRI
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEE
AMDERGELWTTRKLVDLAKDWQMHSVRRIAFLIGASDGHTEELRSRCNHILSLSKFTLQH
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ELALVVLLEQLYRCHTILAGTPYHR
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQFLILAAGKPSLGYAKEGVELYLNRLRPFGKTELKLVRDGSSQDVSKRLLAASEGCLRI
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEE
AMDERGELWTTRKLVDLAKDWQMHSVRRIAFLIGASDGHTEELRSRCNHILSLSKFTLQH
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ELALVVLLEQLYRCHTILAGTPYHR
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA