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The map label for this gene is aroB [H]

Identifier: 187735712

GI number: 187735712

Start: 1457240

End: 1458352

Strand: Reverse

Name: aroB [H]

Synonym: Amuc_1218

Alternate gene names: 187735712

Gene position: 1458352-1457240 (Counterclockwise)

Preceding gene: 187735713

Following gene: 187735710

Centisome position: 54.74

GC content: 55.71

Gene sequence:

>1113_bases
ATGCCTACCATTTCTCTTGCTCTCGGTGAACGTTCCTACGACATCCACGTGGAAAACGGAGCACTGGACCGTACCGGAGA
GTTTGCCTACCGCGCCGGTCTGGACGGCAAGATTGCGGTTATCACGGACAGCTGCGTCGCCCCACTTTATGCAGAGCGCG
TAATGAAGTCCCTGGAGAGCGCGGGATTCATGCCCAGCCTGCACGTAGTGAATGCCGGGGAAGCTTCCAAAAATATGCTT
CAGGCCCAGGAGCTGTGTTCCGAACTGGTCCGGGCCGGGCTTGACCGCACCGGATGCATCGCCGCTCTGGGCGGCGGCGT
AGTAGGGGATCTGGCCGGCTTCATCGCTTCCATTTATTACCGGGGCATCCCCTTCATGCAAATTCCAACAACGGTGGTCG
CCCAGGTGGACAGTTCCGTAGGAGGAAAGACTGCCGTCAATATTCCAGAAGGGAAAAATCTTGTAGGAGCCTTTCATCAG
CCGTCCGTCGTGGTAATCGACCCTACCACGCTGGTGACTTTGGATCGACGTACGCTGGCGGAAGGTTTGGCGGAAGCCGT
CAAGCACGCAGCTATCAAAGACGCTTCCATGCTTCATGAATTGAAAGGGCTGGGGCCGGAACTCTCCATCGGCTTCTCCC
TGAATACTATTGCCAGGCTTCCTGACCTAATCTCCCGGAACGTGGCCATTAAGGCCCGCATTGTAGAAAATGATGAATTG
GAAACTCTGGATATCCGGGCTCTGCTCAATTTCGGCCACACCATCGGCCACGGCATTGAAGCTGCCGTCCCTTACGGAAC
CATCCTTCACGGGGAAGCAGTGGCGCTCGGCATGCGCGCCGCCCTGTTTCTGAGTGAACGGAAAGCCGGTTTAAGTTCTT
CCGATGCCAACAAGATCCTTCGCACGCTTCAGGCGCTGGAACTTCCCTTGGTTCTTCCGGACGGCATTGATACGGCAACT
GTTCTTCAAAAAACGGCATCAGACAAAAAGTTCCGGGCCGGAACCATCCGCTTTGTTCTGCTTTCCAAAGCAGGGGAGGC
AGGCATTTCTACGAAAATTACTCGGGAAGATATGGCGGAAGCCATTGAAGAATTGCGCCGCCCCCTGGATTGA

Upstream 100 bases:

>100_bases
GGCACCCAGGACAAGAACGCATTAAAAGGAGAATGCGTCTTCTTCGCCTCATCCGCACTTTCCGTTTGAGGTTCCCTCCG
GAATATCCCATACTGGCCTC

Downstream 100 bases:

>100_bases
GTTTACCACCCGTGGCCCTTTGTTCTCCAGCAAGAAAACTCCGGGAGTCGGGCTGTACAGATATTTTCCCCTTCTCTTCG
CGCATTTTCCCATCAGGAAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MPTISLALGERSYDIHVENGALDRTGEFAYRAGLDGKIAVITDSCVAPLYAERVMKSLESAGFMPSLHVVNAGEASKNML
QAQELCSELVRAGLDRTGCIAALGGGVVGDLAGFIASIYYRGIPFMQIPTTVVAQVDSSVGGKTAVNIPEGKNLVGAFHQ
PSVVVIDPTTLVTLDRRTLAEGLAEAVKHAAIKDASMLHELKGLGPELSIGFSLNTIARLPDLISRNVAIKARIVENDEL
ETLDIRALLNFGHTIGHGIEAAVPYGTILHGEAVALGMRAALFLSERKAGLSSSDANKILRTLQALELPLVLPDGIDTAT
VLQKTASDKKFRAGTIRFVLLSKAGEAGISTKITREDMAEAIEELRRPLD

Sequences:

>Translated_370_residues
MPTISLALGERSYDIHVENGALDRTGEFAYRAGLDGKIAVITDSCVAPLYAERVMKSLESAGFMPSLHVVNAGEASKNML
QAQELCSELVRAGLDRTGCIAALGGGVVGDLAGFIASIYYRGIPFMQIPTTVVAQVDSSVGGKTAVNIPEGKNLVGAFHQ
PSVVVIDPTTLVTLDRRTLAEGLAEAVKHAAIKDASMLHELKGLGPELSIGFSLNTIARLPDLISRNVAIKARIVENDEL
ETLDIRALLNFGHTIGHGIEAAVPYGTILHGEAVALGMRAALFLSERKAGLSSSDANKILRTLQALELPLVLPDGIDTAT
VLQKTASDKKFRAGTIRFVLLSKAGEAGISTKITREDMAEAIEELRRPLD
>Mature_369_residues
PTISLALGERSYDIHVENGALDRTGEFAYRAGLDGKIAVITDSCVAPLYAERVMKSLESAGFMPSLHVVNAGEASKNMLQ
AQELCSELVRAGLDRTGCIAALGGGVVGDLAGFIASIYYRGIPFMQIPTTVVAQVDSSVGGKTAVNIPEGKNLVGAFHQP
SVVVIDPTTLVTLDRRTLAEGLAEAVKHAAIKDASMLHELKGLGPELSIGFSLNTIARLPDLISRNVAIKARIVENDELE
TLDIRALLNFGHTIGHGIEAAVPYGTILHGEAVALGMRAALFLSERKAGLSSSDANKILRTLQALELPLVLPDGIDTATV
LQKTASDKKFRAGTIRFVLLSKAGEAGISTKITREDMAEAIEELRRPLD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=372, Percent_Identity=39.5161290322581, Blast_Score=224, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320332, Length=341, Percent_Identity=33.1378299120235, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39258; Mature: 39127

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTISLALGERSYDIHVENGALDRTGEFAYRAGLDGKIAVITDSCVAPLYAERVMKSLES
CCEEEEEECCCCEEEEECCCCCCCCCCHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHH
AGFMPSLHVVNAGEASKNMLQAQELCSELVRAGLDRTGCIAALGGGVVGDLAGFIASIYY
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHH
RGIPFMQIPTTVVAQVDSSVGGKTAVNIPEGKNLVGAFHQPSVVVIDPTTLVTLDRRTLA
CCCCCEECCHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCEEEECCCEEEEECHHHHH
EGLAEAVKHAAIKDASMLHELKGLGPELSIGFSLNTIARLPDLISRNVAIKARIVENDEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCC
ETLDIRALLNFGHTIGHGIEAAVPYGTILHGEAVALGMRAALFLSERKAGLSSSDANKIL
CHHHHHHHHHCCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RTLQALELPLVLPDGIDTATVLQKTASDKKFRAGTIRFVLLSKAGEAGISTKITREDMAE
HHHHHHCCCEECCCCCCHHHHHHHHCCCCCEECCEEEEEEEECCCCCCCCCEECHHHHHH
AIEELRRPLD
HHHHHHCCCC
>Mature Secondary Structure 
PTISLALGERSYDIHVENGALDRTGEFAYRAGLDGKIAVITDSCVAPLYAERVMKSLES
CEEEEEECCCCEEEEECCCCCCCCCCHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHH
AGFMPSLHVVNAGEASKNMLQAQELCSELVRAGLDRTGCIAALGGGVVGDLAGFIASIYY
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHH
RGIPFMQIPTTVVAQVDSSVGGKTAVNIPEGKNLVGAFHQPSVVVIDPTTLVTLDRRTLA
CCCCCEECCHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCEEEECCCEEEEECHHHHH
EGLAEAVKHAAIKDASMLHELKGLGPELSIGFSLNTIARLPDLISRNVAIKARIVENDEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCC
ETLDIRALLNFGHTIGHGIEAAVPYGTILHGEAVALGMRAALFLSERKAGLSSSDANKIL
CHHHHHHHHHCCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RTLQALELPLVLPDGIDTATVLQKTASDKKFRAGTIRFVLLSKAGEAGISTKITREDMAE
HHHHHHCCCEECCCCCCHHHHHHHHCCCCCEECCEEEEEEEECCCCCCCCCEECHHHHHH
AIEELRRPLD
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA