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The map label for this gene is argB

Identifier: 187735697

GI number: 187735697

Start: 1438840

End: 1439733

Strand: Reverse

Name: argB

Synonym: Amuc_1203

Alternate gene names: 187735697

Gene position: 1439733-1438840 (Counterclockwise)

Preceding gene: 187735698

Following gene: 187735696

Centisome position: 54.04

GC content: 57.16

Gene sequence:

>894_bases
ATGGACTCCAAAATCACCCGCCTGATTGAACAGGCCTCCGTCATTGTCGGCGCCCTCCCCTACCTCCAGGCCTACCGGGA
CAAAACATTCCTCATCAAATTCGGCGGCAGCGCCATGGATGACGCCCGCCTGGTCAAAAAGCTCATGCGGGACATCGTTC
TGCTGGAAGTCCTGGGCTTCAACCCCGTGATTGTCCACGGCGGGGGCAAAGCCATTTCCAAGGCGATGGCGGAGGCAGGG
CTGGAAGCCCGTTTCGTCAACGGGCTTCGCGTCACGACTCCGGAAGCCATTTCCATTGTGGAACGCACCCTTTCCGGAAC
CATCAATCCTGGTCTGGTTCAAATGTTCCGCGACTACGGCGGCAAGGGCGTAGGCATTCCCGGCACGGAAATCTTCGTTG
GGGAACGCATCCATGAAAAAGATGAACAGGGTAACCCCATAGATATCGGTGAAGTGGGCAACGTCATCGGTTGCCTGACG
GAGCGCATCACGGAAGCGCTGGAACTCCAGATCACCCCCATCGTCTCTCCGCTGGCAAAAGAACTGGGCACCCATAAACC
GCTCAATGTGAACGCAGACTTGGCAGCCGCCGCCCTTGCCAAGGAACTCAAGCCGGTGAAACTCATCTATATTTCCGATG
TCCCCGGAATTATGAAAGACCCTTCGGATCCCTCCACCCTCATCAAATCCGTCACGCGTACGGAAGCCCTCGACCTTATC
AAGGACGGCACCGTATCCGGCGGCATGATACCTAAAATCCACTCCGCCATTGACGCCCTGAACGCAGGTGTGCGCAAAGT
GCACTTCATTGACGGACGCCTTCCCCACACCCTGCTGCTGGAAATTTTCACTCCGGACGGCATCGGCACGGAAATCATCC
GGGAACAACGCTGA

Upstream 100 bases:

>100_bases
TGCCCCTGGTTTACTTCAGAAGCAGGCGCCTGCTTTGAACGGGTCCTGCCTCAAAATCTCCCTCTCCTTCCGTTAAAACT
CCTACCGTTTCATTACTGAC

Downstream 100 bases:

>100_bases
CTCCCCCGCCGTGAAATTTTCCCTCTTTCTCCCGGCCCTGTTCCTGCTGGCGGCATCCTGCTCCATGCAGCCCACTCCCG
CCCGCCTCTCCGGCTCCTGG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MDSKITRLIEQASVIVGALPYLQAYRDKTFLIKFGGSAMDDARLVKKLMRDIVLLEVLGFNPVIVHGGGKAISKAMAEAG
LEARFVNGLRVTTPEAISIVERTLSGTINPGLVQMFRDYGGKGVGIPGTEIFVGERIHEKDEQGNPIDIGEVGNVIGCLT
ERITEALELQITPIVSPLAKELGTHKPLNVNADLAAAALAKELKPVKLIYISDVPGIMKDPSDPSTLIKSVTRTEALDLI
KDGTVSGGMIPKIHSAIDALNAGVRKVHFIDGRLPHTLLLEIFTPDGIGTEIIREQR

Sequences:

>Translated_297_residues
MDSKITRLIEQASVIVGALPYLQAYRDKTFLIKFGGSAMDDARLVKKLMRDIVLLEVLGFNPVIVHGGGKAISKAMAEAG
LEARFVNGLRVTTPEAISIVERTLSGTINPGLVQMFRDYGGKGVGIPGTEIFVGERIHEKDEQGNPIDIGEVGNVIGCLT
ERITEALELQITPIVSPLAKELGTHKPLNVNADLAAAALAKELKPVKLIYISDVPGIMKDPSDPSTLIKSVTRTEALDLI
KDGTVSGGMIPKIHSAIDALNAGVRKVHFIDGRLPHTLLLEIFTPDGIGTEIIREQR
>Mature_297_residues
MDSKITRLIEQASVIVGALPYLQAYRDKTFLIKFGGSAMDDARLVKKLMRDIVLLEVLGFNPVIVHGGGKAISKAMAEAG
LEARFVNGLRVTTPEAISIVERTLSGTINPGLVQMFRDYGGKGVGIPGTEIFVGERIHEKDEQGNPIDIGEVGNVIGCLT
ERITEALELQITPIVSPLAKELGTHKPLNVNADLAAAALAKELKPVKLIYISDVPGIMKDPSDPSTLIKSVTRTEALDLI
KDGTVSGGMIPKIHSAIDALNAGVRKVHFIDGRLPHTLLLEIFTPDGIGTEIIREQR

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=286, Percent_Identity=25.5244755244755, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI145693208, Length=269, Percent_Identity=29.7397769516729, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320913, Length=279, Percent_Identity=26.8817204301075, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_AKKM8 (B2URE3)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001877809.1
- ProteinModelPortal:   B2URE3
- SMR:   B2URE3
- GeneID:   6273848
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1203
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   CLSK2337883
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31953; Mature: 31953

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: BINDING 90-90 BINDING 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKITRLIEQASVIVGALPYLQAYRDKTFLIKFGGSAMDDARLVKKLMRDIVLLEVLGF
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
NPVIVHGGGKAISKAMAEAGLEARFVNGLRVTTPEAISIVERTLSGTINPGLVQMFRDYG
CCEEEECCCHHHHHHHHHCCCHHHHCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GKGVGIPGTEIFVGERIHEKDEQGNPIDIGEVGNVIGCLTERITEALELQITPIVSPLAK
CCCCCCCCCEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHH
ELGTHKPLNVNADLAAAALAKELKPVKLIYISDVPGIMKDPSDPSTLIKSVTRTEALDLI
HHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHH
KDGTVSGGMIPKIHSAIDALNAGVRKVHFIDGRLPHTLLLEIFTPDGIGTEIIREQR
HCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHCCC
>Mature Secondary Structure
MDSKITRLIEQASVIVGALPYLQAYRDKTFLIKFGGSAMDDARLVKKLMRDIVLLEVLGF
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
NPVIVHGGGKAISKAMAEAGLEARFVNGLRVTTPEAISIVERTLSGTINPGLVQMFRDYG
CCEEEECCCHHHHHHHHHCCCHHHHCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GKGVGIPGTEIFVGERIHEKDEQGNPIDIGEVGNVIGCLTERITEALELQITPIVSPLAK
CCCCCCCCCEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHH
ELGTHKPLNVNADLAAAALAKELKPVKLIYISDVPGIMKDPSDPSTLIKSVTRTEALDLI
HHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHH
KDGTVSGGMIPKIHSAIDALNAGVRKVHFIDGRLPHTLLLEIFTPDGIGTEIIREQR
HCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA