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The map label for this gene is galE [H]

Identifier: 187735620

GI number: 187735620

Start: 1348313

End: 1349302

Strand: Reverse

Name: galE [H]

Synonym: Amuc_1125

Alternate gene names: 187735620

Gene position: 1349302-1348313 (Counterclockwise)

Preceding gene: 187735626

Following gene: 187735619

Centisome position: 50.65

GC content: 57.47

Gene sequence:

>990_bases
ATGAAAGTACTTGTAACCGGCGGAGCCGGATATATTGGTTCCCACACGGTACGCCAGCTCGTCAAAACCGGCGCAGACGT
GACCGTGCTGGACAACATGGTGTACGGCCACGCGGGAGCCCTCGTGGACCCGGAAGTGAAACTGGTCAAAGGGGATTTGG
GAGATGCCTCCGTGGTATATCCTCTCCTGATGAAGGGCAACTTTGACGCCGTGATTCACTTTGCCGCCTTCATCAATGTG
GGGGAATCCGTCCAGAACCCCCTCAAGTACTACATGAACAACATCGCCAGGCCCCTCGTCCTTCTGGGCGCCATGCAAGC
CGCCGGCGTCAAGCGCTTTGTTTTCTCCTCCACCTGCGCCACGTATGGCGTTCCCACCCAGATCCCTATCCCGGAAACGG
AAAAGCAGGATCCTATCAATCCTTACGGGAGTTCCAAGTACATGCTGGAAAAAGTTTGCAGGGACTGCGACCGCGCCTGG
GGTCTCAAAAGCGTTTTTCTGCGCTATTTTAATGCCTCAGGCTGCAGCGAGGACGGCTTGATTGGTGAAGACCACGAACC
AGAAACCCACCTTATCCCCAACATCCTGCTCACGCTGACTGGGGAAAAGGAATACATCGAAGTCTTCGGAACGGATTACG
ACACGCCGGACGGCACCTGCATCCGCGACTACATCCACGTCAACGACCTGGCGGACGCCCACTTAAAAGCGGTGGACTAC
CTGATGAAAGGCGGGGCCACAGAATGCTTCAACCTCGGAACCGGCCTGGGACTTTCCGTCCGGGAAATCCTGGAAACGGC
TGAAAAAGTCACCGGCAAAAAAATTCCCGTCCGCTACGGCCCGCGCCGTGAAGGCGACCCGCCCCGCCTGATTGCCAACC
CGAAGAAAGCCAAGGAAATCCTCGGCTGGGAAGCCAGGTGCAAGGATGCCGGGGCCATTGTGGAAACCGCATGGAAGTGG
ATGACCGGCCCGCGCCGCGGCCACTATTAA

Upstream 100 bases:

>100_bases
CAGCCTGCAGTGAACCGGAAGGTTCCGCAGACTCCAAAATGTCCGGACGCCTTTGCCGGAGAAAAAGTTAAACCGGCTCA
ACAGCAAATTTGATAAAATC

Downstream 100 bases:

>100_bases
TGCCTCTACCCGCAAAAGGCCACCCTCTTTTCCGCCCTGCCATGCCCTCCATGGCAGGGCTTGTTTTTTCAAATTTCTTC
GTACACTCCTCTCCCGGAAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKVLVTGGAGYIGSHTVRQLVKTGADVTVLDNMVYGHAGALVDPEVKLVKGDLGDASVVYPLLMKGNFDAVIHFAAFINV
GESVQNPLKYYMNNIARPLVLLGAMQAAGVKRFVFSSTCATYGVPTQIPIPETEKQDPINPYGSSKYMLEKVCRDCDRAW
GLKSVFLRYFNASGCSEDGLIGEDHEPETHLIPNILLTLTGEKEYIEVFGTDYDTPDGTCIRDYIHVNDLADAHLKAVDY
LMKGGATECFNLGTGLGLSVREILETAEKVTGKKIPVRYGPRREGDPPRLIANPKKAKEILGWEARCKDAGAIVETAWKW
MTGPRRGHY

Sequences:

>Translated_329_residues
MKVLVTGGAGYIGSHTVRQLVKTGADVTVLDNMVYGHAGALVDPEVKLVKGDLGDASVVYPLLMKGNFDAVIHFAAFINV
GESVQNPLKYYMNNIARPLVLLGAMQAAGVKRFVFSSTCATYGVPTQIPIPETEKQDPINPYGSSKYMLEKVCRDCDRAW
GLKSVFLRYFNASGCSEDGLIGEDHEPETHLIPNILLTLTGEKEYIEVFGTDYDTPDGTCIRDYIHVNDLADAHLKAVDY
LMKGGATECFNLGTGLGLSVREILETAEKVTGKKIPVRYGPRREGDPPRLIANPKKAKEILGWEARCKDAGAIVETAWKW
MTGPRRGHY
>Mature_329_residues
MKVLVTGGAGYIGSHTVRQLVKTGADVTVLDNMVYGHAGALVDPEVKLVKGDLGDASVVYPLLMKGNFDAVIHFAAFINV
GESVQNPLKYYMNNIARPLVLLGAMQAAGVKRFVFSSTCATYGVPTQIPIPETEKQDPINPYGSSKYMLEKVCRDCDRAW
GLKSVFLRYFNASGCSEDGLIGEDHEPETHLIPNILLTLTGEKEYIEVFGTDYDTPDGTCIRDYIHVNDLADAHLKAVDY
LMKGGATECFNLGTGLGLSVREILETAEKVTGKKIPVRYGPRREGDPPRLIANPKKAKEILGWEARCKDAGAIVETAWKW
MTGPRRGHY

Specific function: Can have functions other than metabolism of galactose. It also could be involved in preparation of carbohydrate residues for incorporation into complex polymers, such as exopolysaccharides [H]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=336, Percent_Identity=42.8571428571429, Blast_Score=242, Evalue=3e-64,
Organism=Homo sapiens, GI56118217, Length=336, Percent_Identity=42.8571428571429, Blast_Score=242, Evalue=3e-64,
Organism=Homo sapiens, GI189083684, Length=336, Percent_Identity=42.8571428571429, Blast_Score=242, Evalue=3e-64,
Organism=Homo sapiens, GI7657641, Length=318, Percent_Identity=25.1572327044025, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI42516563, Length=309, Percent_Identity=27.5080906148867, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=39.2961876832845, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1788353, Length=368, Percent_Identity=27.9891304347826, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI48994969, Length=288, Percent_Identity=29.8611111111111, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790049, Length=289, Percent_Identity=28.3737024221453, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788365, Length=343, Percent_Identity=23.0320699708455, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=353, Percent_Identity=39.0934844192635, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71982038, Length=355, Percent_Identity=38.8732394366197, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17568069, Length=338, Percent_Identity=25.1479289940828, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=322, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=326, Percent_Identity=24.5398773006135, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=347, Percent_Identity=41.4985590778098, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=37.9710144927536, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21356223, Length=311, Percent_Identity=26.6881028938907, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36071; Mature: 36071

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGAGYIGSHTVRQLVKTGADVTVLDNMVYGHAGALVDPEVKLVKGDLGDASVVY
CEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCEECCCEEEEECCCCCHHHHH
PLLMKGNFDAVIHFAAFINVGESVQNPLKYYMNNIARPLVLLGAMQAAGVKRFVFSSTCA
HHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYGVPTQIPIPETEKQDPINPYGSSKYMLEKVCRDCDRAWGLKSVFLRYFNASGCSEDGL
HCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
IGEDHEPETHLIPNILLTLTGEKEYIEVFGTDYDTPDGTCIRDYIHVNDLADAHLKAVDY
CCCCCCCCHHHCCEEEEEECCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
LMKGGATECFNLGTGLGLSVREILETAEKVTGKKIPVRYGPRREGDPPRLIANPKKAKEI
HHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LGWEARCKDAGAIVETAWKWMTGPRRGHY
HCHHHHCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKVLVTGGAGYIGSHTVRQLVKTGADVTVLDNMVYGHAGALVDPEVKLVKGDLGDASVVY
CEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCEECCCEEEEECCCCCHHHHH
PLLMKGNFDAVIHFAAFINVGESVQNPLKYYMNNIARPLVLLGAMQAAGVKRFVFSSTCA
HHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYGVPTQIPIPETEKQDPINPYGSSKYMLEKVCRDCDRAWGLKSVFLRYFNASGCSEDGL
HCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
IGEDHEPETHLIPNILLTLTGEKEYIEVFGTDYDTPDGTCIRDYIHVNDLADAHLKAVDY
CCCCCCCCHHHCCEEEEEECCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
LMKGGATECFNLGTGLGLSVREILETAEKVTGKKIPVRYGPRREGDPPRLIANPKKAKEI
HHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LGWEARCKDAGAIVETAWKWMTGPRRGHY
HCHHHHCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788721 [H]