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The map label for this gene is clpX [H]

Identifier: 187735545

GI number: 187735545

Start: 1252607

End: 1253977

Strand: Reverse

Name: clpX [H]

Synonym: Amuc_1050

Alternate gene names: 187735545

Gene position: 1253977-1252607 (Counterclockwise)

Preceding gene: 187735546

Following gene: 187735544

Centisome position: 47.07

GC content: 56.75

Gene sequence:

>1371_bases
ATGTCCGGTTCCACCCCTCATCTTCCTGCCTGTTCCTGCTGCGGCAAGCCCGGGAACAAGGTGGACAAACTCATCCAGAT
TGCGGAAGACTTTTACATCTGCAACAATTGCGTTGAAATTTGCGTCAACATGATTGTGAAGGACACAGGCCTTCCGATGG
CGACCCGCTTCATCCGCGGCATCCTGAACATGGAACCCTCCGCTTACGCCATGTGCCAGGCGGAGGCCCGCAAAGCGGCA
GCCGCGGACATGCTCAGGGAAACGGCGGCCGGCCCGGCCTCCTATGAAGGCCCGCTGCCCACACCGGAAGAAATGTGCGC
TACGCTCAACCAGTATGTCATCGGTCAGGACTACGCCAAAAAAGTGCTTTCCGTAGCCGTGTACAACCACTACATGCGCC
TGCGCCAAAGTGCTGTCATGCTGGACGACAAGTCCCTGGACGATGTGGAAATTGAAAAATCCAACATCCTGCTGGCCGGC
CCCACCGGCTCAGGAAAAACCCTGCTGGCGAAAACGCTGGCGAAAATGCTCAACGTCCCATTCTGCATTGTGGACGCCAC
CACGCTGACGGAAGCCGGTTACGTAGGGGAAGATGTGGAAAACATCATCCTGCGCCTGCTCCAGGCTGCCAACTTTGACG
TAGCGAAAGCGGAACAAGGCATCATCTACGTGGATGAAATCGACAAAATCGGACGCAAAACACAGAATGTCTCCGTCACG
AGAGACGTCTCCGGGGAAGGCGTGCAGCAGGCTCTGCTGAAAATCATTGAAGGCACCATCTGCAATGTTCCTCCCACCGG
AGGCCGCAAGCACCCGCAACAGGAATACATCCGCGTCAATACGGAAAAAATCCTCTTCATTGTGGGCGGCGCTTTCGTCG
GGCTGGAAGACATCATCCGCAAACGCCTCGGCGCCACCCAGATGGGATTCGGAGCCATCACGGAACAACGCGACCGCAAG
GAATACTCGGAAGAGGAAATACTGGCACAGGCCATGCCGGAAGACCTCTTCTCCTTCGGCATGATTCCGGAATTCGTGGG
ACGCCTGCCCATCTTCTGTCCGCTCTCCAAGCTGGATGAAAGCCAGCTCGTCCGCCTTCTTACGGAACCCAAAAACGCCC
TGGTCAAGCAATATTCCAAACTGCTCGCCATGTACGGCGCCAAACTGGACGTGCTGCCGGACGCCCTGAAAGCCATGGCC
GCCGAAGCCATGAAACGCGGCACGGGAGCCCGCGCTCTGCGTTCCATCTTTGAAACCCTCATGCTGGACGTCATGTACAA
AGTGCCCAGCATGAAAAATGCGGACACCGTTACCATTACCAGGGAAACGGTTACCGGCAACAAGCCGGCCCAAATCCACC
AGTCCTCCTAA

Upstream 100 bases:

>100_bases
GGATAAAGTTCTGGCGCATCACTCTGATGACCAGGGCGACAAGAAAAAAACCAAGGCCTGACCCTTTCCCTCCGCCATTT
CTCTCTCTACCTGAAAAACC

Downstream 100 bases:

>100_bases
CCTCCCCTCCCTGTTCTTCCTCCATGCCGGAATCCCTTACCGTTCTGGGAATAGAATCCTCCTGTGATGAAACGGCAGTC
GCCATCCTGCGTTCTGCCGG

Product: ATP-dependent Clp protease, ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSGSTPHLPACSCCGKPGNKVDKLIQIAEDFYICNNCVEICVNMIVKDTGLPMATRFIRGILNMEPSAYAMCQAEARKAA
AADMLRETAAGPASYEGPLPTPEEMCATLNQYVIGQDYAKKVLSVAVYNHYMRLRQSAVMLDDKSLDDVEIEKSNILLAG
PTGSGKTLLAKTLAKMLNVPFCIVDATTLTEAGYVGEDVENIILRLLQAANFDVAKAEQGIIYVDEIDKIGRKTQNVSVT
RDVSGEGVQQALLKIIEGTICNVPPTGGRKHPQQEYIRVNTEKILFIVGGAFVGLEDIIRKRLGATQMGFGAITEQRDRK
EYSEEEILAQAMPEDLFSFGMIPEFVGRLPIFCPLSKLDESQLVRLLTEPKNALVKQYSKLLAMYGAKLDVLPDALKAMA
AEAMKRGTGARALRSIFETLMLDVMYKVPSMKNADTVTITRETVTGNKPAQIHQSS

Sequences:

>Translated_456_residues
MSGSTPHLPACSCCGKPGNKVDKLIQIAEDFYICNNCVEICVNMIVKDTGLPMATRFIRGILNMEPSAYAMCQAEARKAA
AADMLRETAAGPASYEGPLPTPEEMCATLNQYVIGQDYAKKVLSVAVYNHYMRLRQSAVMLDDKSLDDVEIEKSNILLAG
PTGSGKTLLAKTLAKMLNVPFCIVDATTLTEAGYVGEDVENIILRLLQAANFDVAKAEQGIIYVDEIDKIGRKTQNVSVT
RDVSGEGVQQALLKIIEGTICNVPPTGGRKHPQQEYIRVNTEKILFIVGGAFVGLEDIIRKRLGATQMGFGAITEQRDRK
EYSEEEILAQAMPEDLFSFGMIPEFVGRLPIFCPLSKLDESQLVRLLTEPKNALVKQYSKLLAMYGAKLDVLPDALKAMA
AEAMKRGTGARALRSIFETLMLDVMYKVPSMKNADTVTITRETVTGNKPAQIHQSS
>Mature_455_residues
SGSTPHLPACSCCGKPGNKVDKLIQIAEDFYICNNCVEICVNMIVKDTGLPMATRFIRGILNMEPSAYAMCQAEARKAAA
ADMLRETAAGPASYEGPLPTPEEMCATLNQYVIGQDYAKKVLSVAVYNHYMRLRQSAVMLDDKSLDDVEIEKSNILLAGP
TGSGKTLLAKTLAKMLNVPFCIVDATTLTEAGYVGEDVENIILRLLQAANFDVAKAEQGIIYVDEIDKIGRKTQNVSVTR
DVSGEGVQQALLKIIEGTICNVPPTGGRKHPQQEYIRVNTEKILFIVGGAFVGLEDIIRKRLGATQMGFGAITEQRDRKE
YSEEEILAQAMPEDLFSFGMIPEFVGRLPIFCPLSKLDESQLVRLLTEPKNALVKQYSKLLAMYGAKLDVLPDALKAMAA
EAMKRGTGARALRSIFETLMLDVMYKVPSMKNADTVTITRETVTGNKPAQIHQSS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=50.3048780487805, Blast_Score=304, Evalue=1e-82,
Organism=Escherichia coli, GI1786642, Length=445, Percent_Identity=51.4606741573034, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1790366, Length=110, Percent_Identity=41.8181818181818, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=309, Percent_Identity=44.0129449838188, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI71982905, Length=309, Percent_Identity=44.0129449838188, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=37.1794871794872, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=248, Percent_Identity=37.0967741935484, Blast_Score=160, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319704, Length=424, Percent_Identity=41.0377358490566, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24648291, Length=326, Percent_Identity=46.6257668711656, Blast_Score=288, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24648289, Length=326, Percent_Identity=46.6257668711656, Blast_Score=287, Evalue=9e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 49902; Mature: 49770

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSTPHLPACSCCGKPGNKVDKLIQIAEDFYICNNCVEICVNMIVKDTGLPMATRFIRG
CCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILNMEPSAYAMCQAEARKAAAADMLRETAAGPASYEGPLPTPEEMCATLNQYVIGQDYAK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
KVLSVAVYNHYMRLRQSAVMLDDKSLDDVEIEKSNILLAGPTGSGKTLLAKTLAKMLNVP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHCCC
FCIVDATTLTEAGYVGEDVENIILRLLQAANFDVAKAEQGIIYVDEIDKIGRKTQNVSVT
EEEEEHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCCEEEEEHHHHHCCCCCCCEEE
RDVSGEGVQQALLKIIEGTICNVPPTGGRKHPQQEYIRVNTEKILFIVGGAFVGLEDIIR
ECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCEEEEEECCHHHCHHHHHH
KRLGATQMGFGAITEQRDRKEYSEEEILAQAMPEDLFSFGMIPEFVGRLPIFCPLSKLDE
HHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHCHHHHHHHCCHHHHHCCCCCCCCHHHCCH
SQLVRLLTEPKNALVKQYSKLLAMYGAKLDVLPDALKAMAAEAMKRGTGARALRSIFETL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLDVMYKVPSMKNADTVTITRETVTGNKPAQIHQSS
HHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SGSTPHLPACSCCGKPGNKVDKLIQIAEDFYICNNCVEICVNMIVKDTGLPMATRFIRG
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILNMEPSAYAMCQAEARKAAAADMLRETAAGPASYEGPLPTPEEMCATLNQYVIGQDYAK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
KVLSVAVYNHYMRLRQSAVMLDDKSLDDVEIEKSNILLAGPTGSGKTLLAKTLAKMLNVP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHCCC
FCIVDATTLTEAGYVGEDVENIILRLLQAANFDVAKAEQGIIYVDEIDKIGRKTQNVSVT
EEEEEHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCCEEEEEHHHHHCCCCCCCEEE
RDVSGEGVQQALLKIIEGTICNVPPTGGRKHPQQEYIRVNTEKILFIVGGAFVGLEDIIR
ECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCEEEEEECCHHHCHHHHHH
KRLGATQMGFGAITEQRDRKEYSEEEILAQAMPEDLFSFGMIPEFVGRLPIFCPLSKLDE
HHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHCHHHHHHHCCHHHHHCCCCCCCCHHHCCH
SQLVRLLTEPKNALVKQYSKLLAMYGAKLDVLPDALKAMAAEAMKRGTGARALRSIFETL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLDVMYKVPSMKNADTVTITRETVTGNKPAQIHQSS
HHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]