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The map label for this gene is sglT [H]

Identifier: 187735471

GI number: 187735471

Start: 1157874

End: 1160171

Strand: Direct

Name: sglT [H]

Synonym: Amuc_0970

Alternate gene names: 187735471

Gene position: 1157874-1160171 (Clockwise)

Preceding gene: 187735470

Following gene: 187735474

Centisome position: 43.46

GC content: 58.96

Gene sequence:

>2298_bases
ATGATGAAAACACTAGCAACCATATTCGGGGCGCTCGCCCTGATGACGTGGGGCGCAGCTGCCCAGGAGGGTCCCGTACC
TGCAACGGCGGCTGATGCGCAGCCCGCCTTGGCCGCTCCGGCCGCGATTCCCGCTGTTGAAGTCCAGCCGGCAGCGGAAA
TTCAGCCGGCGGCTCCCGCCGCAGAGGCAGTACAGGCTGAACAGACCGCCTCTGCGGAGCCTAAAACGGCCCCTCTTTCC
ATGGTGGAAGTCATTCTCTTCTGCGTGGTCGTGGTGGGCGTGATCGCCCTGGGCATCTGGAAGAGCCGTGACCCCGAAGA
AACGGAAGAGGAAAAGAAGGCCAAGGGCGCTTCAGACTATTTCCTTGCCGGCCGCGGTTTGACCTGGTGGCTGGTGGGTT
TCTCCCTGATTGCCGCCAACATTTCCACGGAACAGTTTGTGGGGATGTCCGGCAAATCGGCCAACTGGGTGGGCATGGCC
ATTGCCGGGTATGAATGGCTGGCCGCTATCACGCTGGTGGTTGTAGCCTTCTGCTTCCTCCCCAAGCTGTTGAAAGGCGG
CGTATATACGATTCCCGAATTCCTGGAATACCGGTATAACACGCTGGCCCGTTCCCTGATGGCCATTGCTACGCTGCTGA
TTCTGGTAGGCGTGCCGACTGCGGGCGTGATTTACGCCGGCGCCAAGGTGATTTCCGTGTTCTTCACGGGATACTCTGCC
ATGGGCATTGACTTCGGCGACATCACCGTCGGCTGCGTTATCATTGCCTTCTGCGCCACGGTATACGTGTTCGTGGGCGG
GTTGAAAGCCTGCGCCTGGACGGACCTGTTCTGGGGCGCCGCCCTGATTGTGGGCGGCGGCGTGGTGGCCTATTTTGCCC
TGACGGAGCTCAGCGGCGCAGACCCGAACCATTTGATTCAATCCGCCGCCGCCAATTCCGGCGCGACGGTCGCCTCCCTG
GGGAATCCTTCGGACAGCCTCTGGCATGGGGTGACGCGCTTTTTTGAGCTGAACTCCGGTGACGCGGCCAGCGGCGTAAA
TACCGTGGGCGGCAAGCTGCACATGATCCGTCCTGCGGATGATGCGGAAATCCCGTGGACGGCTCTTTGCCTGGGCCTGT
GGATTCCCAACTTCTTTTACTGGGGCCTCAACCAGTACATCATGCAGCGTACGCTGGCTTCCAAATCCCTGGCGGAAGGT
CAGATGGGCATTGTGTTCGCCGCATTCCTCAAGCTCATCATCCCATTCGTGGTGGTGGTCCCCGGCATCCTGGCCTATAA
CCTGTACCGCAATGACCTGAAGGAACAGGCGGAAGTAAAATACGCGGCGGAAATCCGTAAGACGGAAGATCCCGCCGCAG
TCAAGGGCCGCCCCGTCATCTACAAGCTTACGGACAGCTTCCTGGTGGAAAACGTGGAGGAAGGCTGTGCCCATGCCATT
CATAACGCGGAAGTAATGAAGGTGGGCGAAGATGTTATGGCCAATTTGAAACAGGCCTGCGCCGATTTGAAGGCGGATGC
CGCCAACGACCAGACTACGCTGGCGGAACGCGCCCCGTTCGTGGAAAAAATCGCTTCCCTTAACAACAAAATCATCAAGC
CGGCCGTGGACAACTCGGATAACTACTATCTGACGGATACGCTGGTAGGCTTTGACTATGACTCCGCCTTCGGCACGTTG
ATCAGGAAGTTGCTTCCCGGCACGGGCTGGACATGGTTTGTGCTTGCGGCCCTCTTTGGAGCGGTGGTGTCTTCCCTGGC
ATCCATGTTGAATTCCGCGTCCACCATCTTTACGATGGATATTTACAACAAGCTGCGCAAAAATGCGGGGCCCACGGAGC
TGGTTACCGTCGGCAAGATTGGTTTGCTGGTGTGCGCCGTGATCGCCCTGACCATTGCTCCGTTCCTGGACAGCCCGGCC
TTTGGCGGCATCTTCAACTTCATTCAGGAATTCCAGGGCTTCCTGAGCCCGGGCGCCCTGTGCGTGTTCCTCTTCGGCTT
CTTTGTGCCCAAGTGCCCGCGCATCTTCGGTTGGCTGGGTATCGTCATTAATGCCCTCCTGTACGGAATCCTGAAGGTAT
GGCAGCCGGAAATGGCCTTCCTGAACCGCATGGCCGTGTGTTTCATCACGGTAGTGGTCATCGGCTTCATCTTCACGGCG
GTGAACGCCGCCCGCGGCGGACAGCCTATCGTGCTGCCCGACAGGGGCGTGGTTGCCCTTCAGTCCTCTTCACGGGCTAA
AATCTTCGGATGGCTCGTGGTTGCCGCGACGGTTGCCCTGTACATCATCTTCTGGTAA

Upstream 100 bases:

>100_bases
TCTGGACGGCTACTGCCAGGAAACGGGCATTGAAACTACGTATCTTGTAACCCGTGCCGGAGAAGGCGCCCGTGTTTTGT
ACCAAGCTTAATCCATACTG

Downstream 100 bases:

>100_bases
TTCAGGGAAGACCTCCAGTCCCGTATTTTCAATCCTCCCGGTTCAGGCCGGGAGGATTTTTCACGTCCGGAACAGACCAT
GCAGCTGGCGCGGCTGAATA

Product: SSS sodium solute transporter superfamily

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MMKTLATIFGALALMTWGAAAQEGPVPATAADAQPALAAPAAIPAVEVQPAAEIQPAAPAAEAVQAEQTASAEPKTAPLS
MVEVILFCVVVVGVIALGIWKSRDPEETEEEKKAKGASDYFLAGRGLTWWLVGFSLIAANISTEQFVGMSGKSANWVGMA
IAGYEWLAAITLVVVAFCFLPKLLKGGVYTIPEFLEYRYNTLARSLMAIATLLILVGVPTAGVIYAGAKVISVFFTGYSA
MGIDFGDITVGCVIIAFCATVYVFVGGLKACAWTDLFWGAALIVGGGVVAYFALTELSGADPNHLIQSAAANSGATVASL
GNPSDSLWHGVTRFFELNSGDAASGVNTVGGKLHMIRPADDAEIPWTALCLGLWIPNFFYWGLNQYIMQRTLASKSLAEG
QMGIVFAAFLKLIIPFVVVVPGILAYNLYRNDLKEQAEVKYAAEIRKTEDPAAVKGRPVIYKLTDSFLVENVEEGCAHAI
HNAEVMKVGEDVMANLKQACADLKADAANDQTTLAERAPFVEKIASLNNKIIKPAVDNSDNYYLTDTLVGFDYDSAFGTL
IRKLLPGTGWTWFVLAALFGAVVSSLASMLNSASTIFTMDIYNKLRKNAGPTELVTVGKIGLLVCAVIALTIAPFLDSPA
FGGIFNFIQEFQGFLSPGALCVFLFGFFVPKCPRIFGWLGIVINALLYGILKVWQPEMAFLNRMAVCFITVVVIGFIFTA
VNAARGGQPIVLPDRGVVALQSSSRAKIFGWLVVAATVALYIIFW

Sequences:

>Translated_765_residues
MMKTLATIFGALALMTWGAAAQEGPVPATAADAQPALAAPAAIPAVEVQPAAEIQPAAPAAEAVQAEQTASAEPKTAPLS
MVEVILFCVVVVGVIALGIWKSRDPEETEEEKKAKGASDYFLAGRGLTWWLVGFSLIAANISTEQFVGMSGKSANWVGMA
IAGYEWLAAITLVVVAFCFLPKLLKGGVYTIPEFLEYRYNTLARSLMAIATLLILVGVPTAGVIYAGAKVISVFFTGYSA
MGIDFGDITVGCVIIAFCATVYVFVGGLKACAWTDLFWGAALIVGGGVVAYFALTELSGADPNHLIQSAAANSGATVASL
GNPSDSLWHGVTRFFELNSGDAASGVNTVGGKLHMIRPADDAEIPWTALCLGLWIPNFFYWGLNQYIMQRTLASKSLAEG
QMGIVFAAFLKLIIPFVVVVPGILAYNLYRNDLKEQAEVKYAAEIRKTEDPAAVKGRPVIYKLTDSFLVENVEEGCAHAI
HNAEVMKVGEDVMANLKQACADLKADAANDQTTLAERAPFVEKIASLNNKIIKPAVDNSDNYYLTDTLVGFDYDSAFGTL
IRKLLPGTGWTWFVLAALFGAVVSSLASMLNSASTIFTMDIYNKLRKNAGPTELVTVGKIGLLVCAVIALTIAPFLDSPA
FGGIFNFIQEFQGFLSPGALCVFLFGFFVPKCPRIFGWLGIVINALLYGILKVWQPEMAFLNRMAVCFITVVVIGFIFTA
VNAARGGQPIVLPDRGVVALQSSSRAKIFGWLVVAATVALYIIFW
>Mature_765_residues
MMKTLATIFGALALMTWGAAAQEGPVPATAADAQPALAAPAAIPAVEVQPAAEIQPAAPAAEAVQAEQTASAEPKTAPLS
MVEVILFCVVVVGVIALGIWKSRDPEETEEEKKAKGASDYFLAGRGLTWWLVGFSLIAANISTEQFVGMSGKSANWVGMA
IAGYEWLAAITLVVVAFCFLPKLLKGGVYTIPEFLEYRYNTLARSLMAIATLLILVGVPTAGVIYAGAKVISVFFTGYSA
MGIDFGDITVGCVIIAFCATVYVFVGGLKACAWTDLFWGAALIVGGGVVAYFALTELSGADPNHLIQSAAANSGATVASL
GNPSDSLWHGVTRFFELNSGDAASGVNTVGGKLHMIRPADDAEIPWTALCLGLWIPNFFYWGLNQYIMQRTLASKSLAEG
QMGIVFAAFLKLIIPFVVVVPGILAYNLYRNDLKEQAEVKYAAEIRKTEDPAAVKGRPVIYKLTDSFLVENVEEGCAHAI
HNAEVMKVGEDVMANLKQACADLKADAANDQTTLAERAPFVEKIASLNNKIIKPAVDNSDNYYLTDTLVGFDYDSAFGTL
IRKLLPGTGWTWFVLAALFGAVVSSLASMLNSASTIFTMDIYNKLRKNAGPTELVTVGKIGLLVCAVIALTIAPFLDSPA
FGGIFNFIQEFQGFLSPGALCVFLFGFFVPKCPRIFGWLGIVINALLYGILKVWQPEMAFLNRMAVCFITVVVIGFIFTA
VNAARGGQPIVLPDRGVVALQSSSRAKIFGWLVVAATVALYIIFW

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=373, Percent_Identity=27.0777479892761, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI17941285, Length=382, Percent_Identity=25.9162303664921, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI4507033, Length=343, Percent_Identity=27.9883381924198, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI110835708, Length=362, Percent_Identity=26.5193370165746, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI4507031, Length=315, Percent_Identity=28.8888888888889, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI109659839, Length=425, Percent_Identity=25.6470588235294, Blast_Score=110, Evalue=8e-24,
Organism=Homo sapiens, GI109659836, Length=370, Percent_Identity=27.2972972972973, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI206597483, Length=340, Percent_Identity=27.6470588235294, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI206597487, Length=369, Percent_Identity=24.390243902439, Blast_Score=93, Evalue=1e-18,
Organism=Escherichia coli, GI1790113, Length=336, Percent_Identity=33.6309523809524, Blast_Score=161, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 81669; Mature: 81669

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKTLATIFGALALMTWGAAAQEGPVPATAADAQPALAAPAAIPAVEVQPAAEIQPAAPA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCH
AEAVQAEQTASAEPKTAPLSMVEVILFCVVVVGVIALGIWKSRDPEETEEEKKAKGASDY
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCE
FLAGRGLTWWLVGFSLIAANISTEQFVGMSGKSANWVGMAIAGYEWLAAITLVVVAFCFL
EEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
PKLLKGGVYTIPEFLEYRYNTLARSLMAIATLLILVGVPTAGVIYAGAKVISVFFTGYSA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
MGIDFGDITVGCVIIAFCATVYVFVGGLKACAWTDLFWGAALIVGGGVVAYFALTELSGA
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
DPNHLIQSAAANSGATVASLGNPSDSLWHGVTRFFELNSGDAASGVNTVGGKLHMIRPAD
CHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEECCCC
DAEIPWTALCLGLWIPNFFYWGLNQYIMQRTLASKSLAEGQMGIVFAAFLKLIIPFVVVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
PGILAYNLYRNDLKEQAEVKYAAEIRKTEDPAAVKGRPVIYKLTDSFLVENVEEGCAHAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
HNAEVMKVGEDVMANLKQACADLKADAANDQTTLAERAPFVEKIASLNNKIIKPAVDNSD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHCCCEECCCCCCCC
NYYLTDTLVGFDYDSAFGTLIRKLLPGTGWTWFVLAALFGAVVSSLASMLNSASTIFTMD
CEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHH
IYNKLRKNAGPTELVTVGKIGLLVCAVIALTIAPFLDSPAFGGIFNFIQEFQGFLSPGAL
HHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHH
CVFLFGFFVPKCPRIFGWLGIVINALLYGILKVWQPEMAFLNRMAVCFITVVVIGFIFTA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VNAARGGQPIVLPDRGVVALQSSSRAKIFGWLVVAATVALYIIFW
HHHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKTLATIFGALALMTWGAAAQEGPVPATAADAQPALAAPAAIPAVEVQPAAEIQPAAPA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCH
AEAVQAEQTASAEPKTAPLSMVEVILFCVVVVGVIALGIWKSRDPEETEEEKKAKGASDY
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCE
FLAGRGLTWWLVGFSLIAANISTEQFVGMSGKSANWVGMAIAGYEWLAAITLVVVAFCFL
EEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
PKLLKGGVYTIPEFLEYRYNTLARSLMAIATLLILVGVPTAGVIYAGAKVISVFFTGYSA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
MGIDFGDITVGCVIIAFCATVYVFVGGLKACAWTDLFWGAALIVGGGVVAYFALTELSGA
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
DPNHLIQSAAANSGATVASLGNPSDSLWHGVTRFFELNSGDAASGVNTVGGKLHMIRPAD
CHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEECCCC
DAEIPWTALCLGLWIPNFFYWGLNQYIMQRTLASKSLAEGQMGIVFAAFLKLIIPFVVVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
PGILAYNLYRNDLKEQAEVKYAAEIRKTEDPAAVKGRPVIYKLTDSFLVENVEEGCAHAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
HNAEVMKVGEDVMANLKQACADLKADAANDQTTLAERAPFVEKIASLNNKIIKPAVDNSD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHCCCEECCCCCCCC
NYYLTDTLVGFDYDSAFGTLIRKLLPGTGWTWFVLAALFGAVVSSLASMLNSASTIFTMD
CEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHH
IYNKLRKNAGPTELVTVGKIGLLVCAVIALTIAPFLDSPAFGGIFNFIQEFQGFLSPGAL
HHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHH
CVFLFGFFVPKCPRIFGWLGIVINALLYGILKVWQPEMAFLNRMAVCFITVVVIGFIFTA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VNAARGGQPIVLPDRGVVALQSSSRAKIFGWLVVAATVALYIIFW
HHHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]