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The map label for this gene is yggV [C]

Identifier: 187735460

GI number: 187735460

Start: 1144360

End: 1145004

Strand: Direct

Name: yggV [C]

Synonym: Amuc_0959

Alternate gene names: 187735460

Gene position: 1144360-1145004 (Clockwise)

Preceding gene: 187735459

Following gene: 187735462

Centisome position: 42.95

GC content: 62.02

Gene sequence:

>645_bases
ATGATTTTCAACTGTAAAAGATTGATGATTATGGAACAGGAATTGCCGCTGCTGGTGGTTGCCACGCGCAACGCCCACAA
GACCGGGGAAATCCGCGCCATGCTGGCCGGGAAATGGGAAGTGAAGGATCTTTCCGACTATCCCCAGGCTCCGCCCGTGG
ATGAAACGGGAGTCACGTTTACGGAGAACGCCACGCTCAAGGCGCTTTCCGCTTCCAGATGCATCCCCGGCGTCCTGCTG
GCGGATGATTCCGGGCTGGAGGTGGATGTGCTGGACGGGCGCCCCGGAGTCTGGTCCTCCTCCTTCGGCGGGGAGGAAGG
GAATCATGCGCGGAATAACCTCCGCATGATGGAGGAACTGCGGCGCGCCGGCGTGAAGCCGGGGGACAGGCCTTCCGCGC
GGTTCCGCTGCGTCATGGTGCTTGCCGGGAACGGCCGCGTGCTGGCGGAGTTTTCCGGTTCCGTGGAAGGCTACATGTTG
ACGGAGCCGGCCGGAGAAGGAGGGTTCGGCTATGATCCGCTGTTTGTCCCGGAAGGGCATGACCGGAGTTTCGCCCAGCT
TCCCATGGAAGTGAAAAATTCCATGTCGCACCGCGCCCGCGCTCTGGCACAGGTGGTGGAGTGGATGAAGGAACGCCGGG
CCTGA

Upstream 100 bases:

>100_bases
TGGCTTCCAGGGTGAAGGATGCCGCCATCCATCCGGATGTGACGGGGTCCGACCATTGCCCCGTCAGCCTGGAGATTGAC
TGCTGAGCGCGGTCTTTCAG

Downstream 100 bases:

>100_bases
GGTCTTTCCCGGACGCCTGGCGGCGGGGAGGTCAGTCCAGCCTGAAGGCGCATATCTGGAAGGGAGCCGGTGTTCCGGTG
TTCAGGAGCTGGTATTTGCC

Product: Ham1 family protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase 2; NTPase 2 [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIFNCKRLMIMEQELPLLVVATRNAHKTGEIRAMLAGKWEVKDLSDYPQAPPVDETGVTFTENATLKALSASRCIPGVLL
ADDSGLEVDVLDGRPGVWSSSFGGEEGNHARNNLRMMEELRRAGVKPGDRPSARFRCVMVLAGNGRVLAEFSGSVEGYML
TEPAGEGGFGYDPLFVPEGHDRSFAQLPMEVKNSMSHRARALAQVVEWMKERRA

Sequences:

>Translated_214_residues
MIFNCKRLMIMEQELPLLVVATRNAHKTGEIRAMLAGKWEVKDLSDYPQAPPVDETGVTFTENATLKALSASRCIPGVLL
ADDSGLEVDVLDGRPGVWSSSFGGEEGNHARNNLRMMEELRRAGVKPGDRPSARFRCVMVLAGNGRVLAEFSGSVEGYML
TEPAGEGGFGYDPLFVPEGHDRSFAQLPMEVKNSMSHRARALAQVVEWMKERRA
>Mature_214_residues
MIFNCKRLMIMEQELPLLVVATRNAHKTGEIRAMLAGKWEVKDLSDYPQAPPVDETGVTFTENATLKALSASRCIPGVLL
ADDSGLEVDVLDGRPGVWSSSFGGEEGNHARNNLRMMEELRRAGVKPGDRPSARFRCVMVLAGNGRVLAEFSGSVEGYML
TEPAGEGGFGYDPLFVPEGHDRSFAQLPMEVKNSMSHRARALAQVVEWMKERRA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=35.7142857142857, Blast_Score=117, Evalue=7e-28,
Organism=Drosophila melanogaster, GI19920712, Length=193, Percent_Identity=31.0880829015544, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 23536; Mature: 23536

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFNCKRLMIMEQELPLLVVATRNAHKTGEIRAMLAGKWEVKDLSDYPQAPPVDETGVTF
CEECCCEEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEE
TENATLKALSASRCIPGVLLADDSGLEVDVLDGRPGVWSSSFGGEEGNHARNNLRMMEEL
ECCCEEEEHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRAGVKPGDRPSARFRCVMVLAGNGRVLAEFSGSVEGYMLTEPAGEGGFGYDPLFVPEGH
HHCCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCCCEECCCCC
DRSFAQLPMEVKNSMSHRARALAQVVEWMKERRA
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFNCKRLMIMEQELPLLVVATRNAHKTGEIRAMLAGKWEVKDLSDYPQAPPVDETGVTF
CEECCCEEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEE
TENATLKALSASRCIPGVLLADDSGLEVDVLDGRPGVWSSSFGGEEGNHARNNLRMMEEL
ECCCEEEEHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRAGVKPGDRPSARFRCVMVLAGNGRVLAEFSGSVEGYMLTEPAGEGGFGYDPLFVPEGH
HHCCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCCCEECCCCC
DRSFAQLPMEVKNSMSHRARALAQVVEWMKERRA
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]