Click here to switch to the map view.

The map label for this gene is xlyA [H]

Identifier: 187735404

GI number: 187735404

Start: 1076612

End: 1077277

Strand: Reverse

Name: xlyA [H]

Synonym: Amuc_0903

Alternate gene names: 187735404

Gene position: 1077277-1076612 (Counterclockwise)

Preceding gene: 187735405

Following gene: 187735403

Centisome position: 40.44

GC content: 57.21

Gene sequence:

>666_bases
ATGGAATATAGATTTGTCTGGACGGGCTTTTTTGCCGTATTCGCCGCCCTGACGTTCTGCAGCTGTTCGCAGAACGACAA
AATGAGGCCGCCGGCCGTCTCCTTTAAAATTCAAAAGGCGCCGGTAGTTCCCCGCACACCCGGCCAGATGGGCCGTGAAG
TAGGCATTAAAGTTTCCTACATGCCCAAAAACACGTATGCCCGCAAGCGCGCATCCTCCATGCGCCCCCGCTTCATCACC
ATCCACAGCACCGCCAACCCCAAAGGAGACGCCAATGCCCACTCCCGTTACCTGAACAGCGGCAAGTCCCGCAGCCTGAA
CTGGCACTTCACTGTGGACCAATTCGGCGCCTACCAGCACATCCCCACTACGGAAACCGGCCACCATGCGGACCATTCCG
GACCGGGAGACCAATACTCCGTAGCCATTGAAATGTGTGAATGCACCACGCATAACCCTGTCGTCATCTACAACAAGACG
GCCAAGCTGGCGGCGCTGCTGATGATGCGCTACAACGTCCCCCTGCGCAACGTAGTGCCTCACAACTACTGGTCCGGCAA
GAATTGCCCCGCCCCGCTGATGACTAATGGGCGCCCCGGGTACAAATGGAGCTGGTTCATTTCCCGCGTGGATTATTACT
ACCGCTGCCTCCAGGCAGGAAGATAA

Upstream 100 bases:

>100_bases
CCGGATATACCTGCAACTTCACGGCACGGCCTGATTAGTTCATCCGAACTAATTCCAAATTCTTCTTGCAATCCTTCCAG
GCTGTTCCTAGAACAAACGC

Downstream 100 bases:

>100_bases
TACTGCCGCATATGCCGCACGCCCCTTTGCCGCTTCCGGCATAAAGAAGGCAGGAAATGTTTCAGGAAAGAACAGGAATC
ACTTCTTTCCCTGAAAATAT

Product: N-acetylmuramoyl-L-alanine amidase family 2

Products: NA

Alternate protein names: Autolysin; Cell wall hydrolase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MEYRFVWTGFFAVFAALTFCSCSQNDKMRPPAVSFKIQKAPVVPRTPGQMGREVGIKVSYMPKNTYARKRASSMRPRFIT
IHSTANPKGDANAHSRYLNSGKSRSLNWHFTVDQFGAYQHIPTTETGHHADHSGPGDQYSVAIEMCECTTHNPVVIYNKT
AKLAALLMMRYNVPLRNVVPHNYWSGKNCPAPLMTNGRPGYKWSWFISRVDYYYRCLQAGR

Sequences:

>Translated_221_residues
MEYRFVWTGFFAVFAALTFCSCSQNDKMRPPAVSFKIQKAPVVPRTPGQMGREVGIKVSYMPKNTYARKRASSMRPRFIT
IHSTANPKGDANAHSRYLNSGKSRSLNWHFTVDQFGAYQHIPTTETGHHADHSGPGDQYSVAIEMCECTTHNPVVIYNKT
AKLAALLMMRYNVPLRNVVPHNYWSGKNCPAPLMTNGRPGYKWSWFISRVDYYYRCLQAGR
>Mature_221_residues
MEYRFVWTGFFAVFAALTFCSCSQNDKMRPPAVSFKIQKAPVVPRTPGQMGREVGIKVSYMPKNTYARKRASSMRPRFIT
IHSTANPKGDANAHSRYLNSGKSRSLNWHFTVDQFGAYQHIPTTETGHHADHSGPGDQYSVAIEMCECTTHNPVVIYNKT
AKLAALLMMRYNVPLRNVVPHNYWSGKNCPAPLMTNGRPGYKWSWFISRVDYYYRCLQAGR

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation [H]

COG id: COG5632

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR002477
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01510 Amidase_2; PF01476 LysM; PF01471 PG_binding_1 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 25181; Mature: 25181

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRFVWTGFFAVFAALTFCSCSQNDKMRPPAVSFKIQKAPVVPRTPGQMGREVGIKVSY
CCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHCHHHCCEEEE
MPKNTYARKRASSMRPRFITIHSTANPKGDANAHSRYLNSGKSRSLNWHFTVDQFGAYQH
ECCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHCCCEEC
IPTTETGHHADHSGPGDQYSVAIEMCECTTHNPVVIYNKTAKLAALLMMRYNVPLRNVVP
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECHHHHHHHHHHHCCCCHHHCCC
HNYWSGKNCPAPLMTNGRPGYKWSWFISRVDYYYRCLQAGR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEYRFVWTGFFAVFAALTFCSCSQNDKMRPPAVSFKIQKAPVVPRTPGQMGREVGIKVSY
CCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHCHHHCCEEEE
MPKNTYARKRASSMRPRFITIHSTANPKGDANAHSRYLNSGKSRSLNWHFTVDQFGAYQH
ECCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHCCCEEC
IPTTETGHHADHSGPGDQYSVAIEMCECTTHNPVVIYNKTAKLAALLMMRYNVPLRNVVP
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECHHHHHHHHHHHCCCCHHHCCC
HNYWSGKNCPAPLMTNGRPGYKWSWFISRVDYYYRCLQAGR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921239; 9555893; 9384377 [H]