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The map label for this gene is bmrR [H]

Identifier: 187735390

GI number: 187735390

Start: 1057369

End: 1058181

Strand: Reverse

Name: bmrR [H]

Synonym: Amuc_0888

Alternate gene names: 187735390

Gene position: 1058181-1057369 (Counterclockwise)

Preceding gene: 187735396

Following gene: 187735389

Centisome position: 39.72

GC content: 54.0

Gene sequence:

>813_bases
ATGGACAAACAGAATTTACTAACCATCGGCAATCTGTCCAAACAGACCGGCGTACATGTCAAATCCCTCCGGTATTATGA
ACAACTGGGCATTTTGCTCCCGGCCTATACGGACCCGGACACCGGCTACCGTTACTACACTCTTTCCCAGATTCCCGTGG
TGGATGCCATCCGCGCCTGCATTTTCCTGGATATTCCCCTGAAGGAATTTACCGGCTTCCTGACCAGGGACCAGCGAAGG
ATCCATTATAAGAAACTTTTCTCCCACGGCACCATGCTGGCACACCGGAAAATCAGGGATATTCAGGAAAAGCTGCGCCT
GCTGGAAAAATTCCGGAAACAGATGGGCCGGGAAGAAGATCTTCTGCTTCATGGGGAACAGGCCATCCACGCATTGCCGG
AAAAATACTGCTGGGTGGCGCCCTATGCGGGAAAACAGCATACTCCGGAATTTAACATTCTTATCACCCGCATCTTTGAC
GATATTAACCGCTGCCAGCTGCGGCTGGGCGCGGAAGCCGGCCTGCTTTCCTTCCACCGGAAAGCAGGGACGGAGCAGTT
CCTGTATGTGGAGGTGGAAGCGGCCGGCAGAGACGCCCGGCGGATGAAGGAAATCATGCGCCTGCCCGCCGCCTCCTTTC
TCTGCGTCATCAGGCAGGAAAGCGGCATTGCGGAGGCGCCCGGCGTTTTTCCGGACCTTTTTGCGCAGGAATATGATAAA
ATCATTATGGAGACGGAATTGTTTCCCGGAGATTACGATGTGGCAAATCCCAAATTCGAACTGAGATGCAGCCTGCCGCC
GGGTGGGAAATGA

Upstream 100 bases:

>100_bases
ACTTCGTCTTCAGAAAGGTTTCTTCTGCGCGCAGCTCCCGTTTCCGCCGGGGCTCTTCCGGCGGAAACAATCAATTCCCT
CCCACCAACCGCAATACAGG

Downstream 100 bases:

>100_bases
ATCCGGAAATTTCCGCGCATCCGCCGGCGGGAGCGGAAGATGCAAAAGCGCTCCCGCCAGCCGGGAACCGCCCCCCGCGA
ACCTCCGCCGCCCTGCGGAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDKQNLLTIGNLSKQTGVHVKSLRYYEQLGILLPAYTDPDTGYRYYTLSQIPVVDAIRACIFLDIPLKEFTGFLTRDQRR
IHYKKLFSHGTMLAHRKIRDIQEKLRLLEKFRKQMGREEDLLLHGEQAIHALPEKYCWVAPYAGKQHTPEFNILITRIFD
DINRCQLRLGAEAGLLSFHRKAGTEQFLYVEVEAAGRDARRMKEIMRLPAASFLCVIRQESGIAEAPGVFPDLFAQEYDK
IIMETELFPGDYDVANPKFELRCSLPPGGK

Sequences:

>Translated_270_residues
MDKQNLLTIGNLSKQTGVHVKSLRYYEQLGILLPAYTDPDTGYRYYTLSQIPVVDAIRACIFLDIPLKEFTGFLTRDQRR
IHYKKLFSHGTMLAHRKIRDIQEKLRLLEKFRKQMGREEDLLLHGEQAIHALPEKYCWVAPYAGKQHTPEFNILITRIFD
DINRCQLRLGAEAGLLSFHRKAGTEQFLYVEVEAAGRDARRMKEIMRLPAASFLCVIRQESGIAEAPGVFPDLFAQEYDK
IIMETELFPGDYDVANPKFELRCSLPPGGK
>Mature_270_residues
MDKQNLLTIGNLSKQTGVHVKSLRYYEQLGILLPAYTDPDTGYRYYTLSQIPVVDAIRACIFLDIPLKEFTGFLTRDQRR
IHYKKLFSHGTMLAHRKIRDIQEKLRLLEKFRKQMGREEDLLLHGEQAIHALPEKYCWVAPYAGKQHTPEFNILITRIFD
DINRCQLRLGAEAGLLSFHRKAGTEQFLYVEVEAAGRDARRMKEIMRLPAASFLCVIRQESGIAEAPGVFPDLFAQEYDK
IIMETELFPGDYDVANPKFELRCSLPPGGK

Specific function: Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind; PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 31107; Mature: 31107

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKQNLLTIGNLSKQTGVHVKSLRYYEQLGILLPAYTDPDTGYRYYTLSQIPVVDAIRAC
CCCCCEEEECCCCHHCCCHHHHHHHHHHHCEEEECCCCCCCCEEEEEECCCCHHHHHHHH
IFLDIPLKEFTGFLTRDQRRIHYKKLFSHGTMLAHRKIRDIQEKLRLLEKFRKQMGREED
HEECCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LLLHGEQAIHALPEKYCWVAPYAGKQHTPEFNILITRIFDDINRCQLRLGAEAGLLSFHR
EEEECHHHHHHCCHHHEEECCCCCCCCCCCHHEEHHHHHHHHHHHHEEECCCHHHHHHHH
KAGTEQFLYVEVEAAGRDARRMKEIMRLPAASFLCVIRQESGIAEAPGVFPDLFAQEYDK
HCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCHHHHHHHHHH
IIMETELFPGDYDVANPKFELRCSLPPGGK
HHHHHCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MDKQNLLTIGNLSKQTGVHVKSLRYYEQLGILLPAYTDPDTGYRYYTLSQIPVVDAIRAC
CCCCCEEEECCCCHHCCCHHHHHHHHHHHCEEEECCCCCCCCEEEEEECCCCHHHHHHHH
IFLDIPLKEFTGFLTRDQRRIHYKKLFSHGTMLAHRKIRDIQEKLRLLEKFRKQMGREED
HEECCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LLLHGEQAIHALPEKYCWVAPYAGKQHTPEFNILITRIFDDINRCQLRLGAEAGLLSFHR
EEEECHHHHHHCCHHHEEECCCCCCCCCCCHHEEHHHHHHHHHHHHEEECCCHHHHHHHH
KAGTEQFLYVEVEAAGRDARRMKEIMRLPAASFLCVIRQESGIAEAPGVFPDLFAQEYDK
HCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCHHHHHHHHHH
IIMETELFPGDYDVANPKFELRCSLPPGGK
HHHHHCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377; 10568751; 10025401; 11201751 [H]