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The map label for this gene is argD [H]

Identifier: 187735374

GI number: 187735374

Start: 1041730

End: 1042986

Strand: Direct

Name: argD [H]

Synonym: Amuc_0872

Alternate gene names: 187735374

Gene position: 1041730-1042986 (Clockwise)

Preceding gene: 187735371

Following gene: 187735375

Centisome position: 39.1

GC content: 61.58

Gene sequence:

>1257_bases
ATGAACACAGAAGAAAAGCTCAACCAGTACGTACTCCATTCCTATGGCCGTTATCCCATGGCTGCCGTCCGCGGAGAAGG
CTCCCGACTGTGGGACAGCACGGGGAAGTGCTATCTGGACTTCTGTGCCGGCATTGCGACCTGCGTGCTCGGGCACTGCC
ATCCTGCGGTGACGCAGGCCCTGCAAAAGCAGGCCGCCACCTTGGTGCACTGCTCCAACCTGTACCAGATCCCCCAGCAG
GCGGATCTGGCGGAATTCATTGTGACCAAATGCGTGGAGCGCCCGGGAAAAGTCTTTTTCTCCAACAGCGGTGCGGAGTC
CAATGACGGTTTAATCAAAGTAGCGCGCCGTTACGGGCACCGCAAGCCCCAGCCGGACGGCAAGCCCCGTTATGAGGTGC
TTACGTTCAACAAATCCTTCCACGGGAGGACGCTGGGCAGCATGTCCGCCACGGGGCAGGATAAAATCAAAATCGGCTTT
GACCCCATGCTGCCGGGATTCCGCCATTTGCCTTTCAACGATCTGGAAACGGCCCGCGAAGCCATCAGGCCGGAAACGGT
GGCCTTCATGCTGGAAACCGTCCAGGGAGAAGGAGGGGTCAACTGCGTGACTCCGGAATTTCTGCGGGGCCTGGCGCAGT
TATGCAGGGAGCACGATCTTCTTCTGCTGATGGATGAAGTGCAGTGCGGCTTTGGCCGTTGCGGCGACATCATGGGATGG
CGCGCCGTAGCTCCGGATGTGGAACCGGACGGCATTTCCTGGGCCAAGGCTCTGGGCGGCGGTTTCCCCATCGGCGGCTT
CTGGATTTCCGACCGCGCCATTGACGGCCAGGGTACGGAGCTTTCCTCCATCATGGATCCCGGCTCCCATGGCTCCACGT
ATGGAGGCAACCCGCTCGGCACTGCGGTAGGCCTGGCCGTGCTGCGGGAAGTTGTTTCCCAGGGGCTCCCGGAGCGGGCG
CGGCGCCTGGGCGCGGAAATTCGCAGGGAAATAGAATCCTGGAACCTGCCTGTTGTTCAGGGCGTGCGTGGCCTGGGCCT
GTTGCTGGGCATTGGCCTGAACCCGGAAATGGTGGCCGCGCCGGAGGGCAAGACGATCGCCTCCGTAGTGGTGGAGGCCC
TGCGGCAGGAAGGGTTGCTTTCCGTTCCCGCCGGGCCGGAAACCGTCCGTCTGCTGCCGCCGCTGAATGTCAGTGAAGAG
GAAATCCAGCAGGCTCTGGCCATCATCAGGCGCGTGCTTAAAACGTACGCCAAATAG

Upstream 100 bases:

>100_bases
TGTCTTCCGGGGTAAAATGCGGCAATCATGACGTGGTTCCCAAAAAAATCATTTACAGACGGGGCCAGAAGAGCAAACTA
CGCCCATATTACCTTAACTT

Downstream 100 bases:

>100_bases
AATACAGCCCTTATTTGCTTTATTGTTATGAAGGAAGAAGCCATTAAAGCCCCCGGCAGCACGATAAAGCAATATTCCAT
CATGCTCCAGAACCGGGTGG

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNTEEKLNQYVLHSYGRYPMAAVRGEGSRLWDSTGKCYLDFCAGIATCVLGHCHPAVTQALQKQAATLVHCSNLYQIPQQ
ADLAEFIVTKCVERPGKVFFSNSGAESNDGLIKVARRYGHRKPQPDGKPRYEVLTFNKSFHGRTLGSMSATGQDKIKIGF
DPMLPGFRHLPFNDLETAREAIRPETVAFMLETVQGEGGVNCVTPEFLRGLAQLCREHDLLLLMDEVQCGFGRCGDIMGW
RAVAPDVEPDGISWAKALGGGFPIGGFWISDRAIDGQGTELSSIMDPGSHGSTYGGNPLGTAVGLAVLREVVSQGLPERA
RRLGAEIRREIESWNLPVVQGVRGLGLLLGIGLNPEMVAAPEGKTIASVVVEALRQEGLLSVPAGPETVRLLPPLNVSEE
EIQQALAIIRRVLKTYAK

Sequences:

>Translated_418_residues
MNTEEKLNQYVLHSYGRYPMAAVRGEGSRLWDSTGKCYLDFCAGIATCVLGHCHPAVTQALQKQAATLVHCSNLYQIPQQ
ADLAEFIVTKCVERPGKVFFSNSGAESNDGLIKVARRYGHRKPQPDGKPRYEVLTFNKSFHGRTLGSMSATGQDKIKIGF
DPMLPGFRHLPFNDLETAREAIRPETVAFMLETVQGEGGVNCVTPEFLRGLAQLCREHDLLLLMDEVQCGFGRCGDIMGW
RAVAPDVEPDGISWAKALGGGFPIGGFWISDRAIDGQGTELSSIMDPGSHGSTYGGNPLGTAVGLAVLREVVSQGLPERA
RRLGAEIRREIESWNLPVVQGVRGLGLLLGIGLNPEMVAAPEGKTIASVVVEALRQEGLLSVPAGPETVRLLPPLNVSEE
EIQQALAIIRRVLKTYAK
>Mature_418_residues
MNTEEKLNQYVLHSYGRYPMAAVRGEGSRLWDSTGKCYLDFCAGIATCVLGHCHPAVTQALQKQAATLVHCSNLYQIPQQ
ADLAEFIVTKCVERPGKVFFSNSGAESNDGLIKVARRYGHRKPQPDGKPRYEVLTFNKSFHGRTLGSMSATGQDKIKIGF
DPMLPGFRHLPFNDLETAREAIRPETVAFMLETVQGEGGVNCVTPEFLRGLAQLCREHDLLLLMDEVQCGFGRCGDIMGW
RAVAPDVEPDGISWAKALGGGFPIGGFWISDRAIDGQGTELSSIMDPGSHGSTYGGNPLGTAVGLAVLREVVSQGLPERA
RRLGAEIRREIESWNLPVVQGVRGLGLLLGIGLNPEMVAAPEGKTIASVVVEALRQEGLLSVPAGPETVRLLPPLNVSEE
EIQQALAIIRRVLKTYAK

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=415, Percent_Identity=34.2168674698795, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI284507298, Length=318, Percent_Identity=34.5911949685535, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI13994255, Length=456, Percent_Identity=27.6315789473684, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI37574042, Length=427, Percent_Identity=24.824355971897, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=25.2336448598131, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI226442709, Length=396, Percent_Identity=24.4949494949495, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226442705, Length=427, Percent_Identity=23.6533957845433, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI188536080, Length=458, Percent_Identity=22.0524017467249, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI38679950, Length=458, Percent_Identity=22.0524017467249, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI38679946, Length=458, Percent_Identity=22.0524017467249, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1789759, Length=408, Percent_Identity=37.0098039215686, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1788044, Length=406, Percent_Identity=37.6847290640394, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI145693181, Length=406, Percent_Identity=33.743842364532, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1789016, Length=442, Percent_Identity=30.316742081448, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787560, Length=417, Percent_Identity=31.89448441247, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786349, Length=354, Percent_Identity=28.8135593220339, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786991, Length=427, Percent_Identity=25.5269320843091, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=408, Percent_Identity=33.0882352941176, Blast_Score=224, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=446, Percent_Identity=27.5784753363229, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=350, Percent_Identity=31.4285714285714, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=26.605504587156, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71981843, Length=181, Percent_Identity=30.939226519337, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=425, Percent_Identity=33.6470588235294, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6323470, Length=430, Percent_Identity=32.093023255814, Blast_Score=212, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6321456, Length=374, Percent_Identity=24.8663101604278, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357415, Length=409, Percent_Identity=32.7628361858191, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI161085790, Length=458, Percent_Identity=27.0742358078603, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28574759, Length=451, Percent_Identity=26.8292682926829, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=26.2790697674419, Blast_Score=128, Evalue=9e-30,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45359; Mature: 45359

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEEKLNQYVLHSYGRYPMAAVRGEGSRLWDSTGKCYLDFCAGIATCVLGHCHPAVTQA
CCCHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
LQKQAATLVHCSNLYQIPQQADLAEFIVTKCVERPGKVFFSNSGAESNDGLIKVARRYGH
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCC
RKPQPDGKPRYEVLTFNKSFHGRTLGSMSATGQDKIKIGFDPMLPGFRHLPFNDLETARE
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHH
AIRPETVAFMLETVQGEGGVNCVTPEFLRGLAQLCREHDLLLLMDEVQCGFGRCGDIMGW
HHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCC
RAVAPDVEPDGISWAKALGGGFPIGGFWISDRAIDGQGTELSSIMDPGSHGSTYGGNPLG
CCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCEECCCCCHHHHHCCCCCCCCCCCCCHHH
TAVGLAVLREVVSQGLPERARRLGAEIRREIESWNLPVVQGVRGLGLLLGIGLNPEMVAA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEC
PEGKTIASVVVEALRQEGLLSVPAGPETVRLLPPLNVSEEEIQQALAIIRRVLKTYAK
CCCCHHHHHHHHHHHHCCCEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTEEKLNQYVLHSYGRYPMAAVRGEGSRLWDSTGKCYLDFCAGIATCVLGHCHPAVTQA
CCCHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
LQKQAATLVHCSNLYQIPQQADLAEFIVTKCVERPGKVFFSNSGAESNDGLIKVARRYGH
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCC
RKPQPDGKPRYEVLTFNKSFHGRTLGSMSATGQDKIKIGFDPMLPGFRHLPFNDLETARE
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHH
AIRPETVAFMLETVQGEGGVNCVTPEFLRGLAQLCREHDLLLLMDEVQCGFGRCGDIMGW
HHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCC
RAVAPDVEPDGISWAKALGGGFPIGGFWISDRAIDGQGTELSSIMDPGSHGSTYGGNPLG
CCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCEECCCCCHHHHHCCCCCCCCCCCCCHHH
TAVGLAVLREVVSQGLPERARRLGAEIRREIESWNLPVVQGVRGLGLLLGIGLNPEMVAA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEC
PEGKTIASVVVEALRQEGLLSVPAGPETVRLLPPLNVSEEEIQQALAIIRRVLKTYAK
CCCCHHHHHHHHHHHHCCCEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]