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The map label for this gene is ybaL [H]

Identifier: 187735217

GI number: 187735217

Start: 839064

End: 840809

Strand: Reverse

Name: ybaL [H]

Synonym: Amuc_0711

Alternate gene names: 187735217

Gene position: 840809-839064 (Counterclockwise)

Preceding gene: 187735219

Following gene: 187735215

Centisome position: 31.56

GC content: 58.48

Gene sequence:

>1746_bases
ATGGATCACGATTTCAGCCTTATTCTCACTTTTGTCGGCGGATTGGCCGCTGCCCTTCTTTTCGGCCTTATTGCCAGAAA
ACTGCATTTATCCCCGCTGGTGGGCTACCTGCTGGCCGGGGTGGCGGTAGGGCCGTACTCGCCGGGATTTGTTGCGGATT
CCCATACGGTGGAACAATTCGCGGAGCTGGGCGTTATCCTGCTGATGTTCGGGGTGGGGCTCCATTTCCATTTGAAGGAT
TTGATTGCCGTGCAAAAAGTGGCCGTGCCGGGAGCCGTTGTGCAGATATCCGTGGCTACCGTGCTGGGGGTGCTGGTCGG
GTGGATGTTCGGATGGTCCGCGATTTCTGGACTGGTTTTTGGCATGGCGATTTCCGTGGCGAGTACCGTAGTGCTGACGC
GGGTGCTGGAAGACAACCAGAACCTCCATACGCCCGGCGGCCATGTGGCCCTGGGATGGCTGGTAGTGGAAGACCTGTTT
ACCATTCTGCTGCTGGTTCTCATCCCCGCCGTGATGGAAGCGCGCCAGAGCGGCGCCGGAGACTGGGGCGGCATTCTTTC
CGAGCTTGGCTGGATGTTCGTCAAGCTGGCCCTGCTGGTGGCCCTGACGCTGTTTGCCGGGAAAAAAGTCATTCCGCTGG
TGCTGCGGTACGTGGCCCGAACGGGCGCGCGTGACTTGTTTACGCTGGCTGTGCTGGTCATTGCGCTGGGCGTGGCGGTG
TGCTCCGCGGAATTCTTTGGCGCTTCCATGGTTTTGGGGGCGTTTTTGGCGGGGATGGTTGTAGGCCAGTCGGACTTCTG
CGCGCGCGCGGCGGCGGAAGCCATGTTGATGAGGGATGCTTTTGCGGTTCTCTTCTTCGTTTCCGTGGGGATGATGTTTG
ACCCGATGTCCGTGGGGGATTGCTGGCCTCTGGCCCTGGCAACGCTGGGGGTGGTGATGATCGGCAAGCCGCTGGCGGCT
TATGTGGTTGTTCGTTGCCTGAGGCGGCCGGTGCCGCTGGCGCTGAGCGTATCCGTGGCCTTGGCTCAAGTGGGTGAATT
TTCTTTCATTCTCGCCGGAATAGGTCTCATGTACAACATCCTGCCTCCGGATGCCAATCAGGCCATCATTCTGGCGGCTG
TCGTCTCCATTTCCTTAAATCCCATCCTGTATCGGCAGATTGGACCTGCAGTCAAATGGCTGCAAAAACGCGGCATAGGG
CTTGCGGACCCGGGGGGCGTGAACAGCATGGCCTTGCCCGCTCCGGATGCGCGGCGCGTGGTATTGGTAGGGTTTGGCCC
CACGGGGCGCATTCTTAAGAGGATATTGAATGACAACGGGGTGGAAGTCATCATCGTGGAAATGAACATAGACACGGTTA
CCGCTATACGGGAGCAGGGAGGGGATATTGTTTACGGGGATGCCAGCCAGCGGGAAATTCTGCGCCATGCGGGCATTGAA
TATGCGGAAAGCCTGATTCTCTCCGCTTCCATTCCGGACGCCAAGGAGATAGTAGGCGTGGCTCTGGAGCTTAACCCTCA
TATTGACGTGATGATTCACACCAAGTACATGAGGGACGTGGATATACTGAAGGAAGCCGGCGCTTCCCAGGTTTTTTCCT
CGGAATCGGAAGTAGCCCTGTCCATGGCGGAATATTTCCTGCGGGAAGGCGGTGCGGACGACGAACAGATCGTTTCCGAG
CGCCAGCGCATTCGCGCGGAGCTGGACAGGGAAATGCCCGGAGTTTCCGTTGCGGGCCATTCATAA

Upstream 100 bases:

>100_bases
TTTCCATGCGGCGCAATGCGTTCTTGTGAGGGAAAATAAAACGCGATAGCGTAAAAACGACTTGGCGGTCAAGAATACCC
CTTATCCCTGTCACGCGCGT

Downstream 100 bases:

>100_bases
TCGTTGGCTCCGCTTTGTCCGGGCGGAGGTTCCCATGCCCGGAATGGAAACCGTTTCTCCTTCCCGGATTCGGAACATGT
TTTTACGGGAATCCGGCAAC

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MDHDFSLILTFVGGLAAALLFGLIARKLHLSPLVGYLLAGVAVGPYSPGFVADSHTVEQFAELGVILLMFGVGLHFHLKD
LIAVQKVAVPGAVVQISVATVLGVLVGWMFGWSAISGLVFGMAISVASTVVLTRVLEDNQNLHTPGGHVALGWLVVEDLF
TILLLVLIPAVMEARQSGAGDWGGILSELGWMFVKLALLVALTLFAGKKVIPLVLRYVARTGARDLFTLAVLVIALGVAV
CSAEFFGASMVLGAFLAGMVVGQSDFCARAAAEAMLMRDAFAVLFFVSVGMMFDPMSVGDCWPLALATLGVVMIGKPLAA
YVVVRCLRRPVPLALSVSVALAQVGEFSFILAGIGLMYNILPPDANQAIILAAVVSISLNPILYRQIGPAVKWLQKRGIG
LADPGGVNSMALPAPDARRVVLVGFGPTGRILKRILNDNGVEVIIVEMNIDTVTAIREQGGDIVYGDASQREILRHAGIE
YAESLILSASIPDAKEIVGVALELNPHIDVMIHTKYMRDVDILKEAGASQVFSSESEVALSMAEYFLREGGADDEQIVSE
RQRIRAELDREMPGVSVAGHS

Sequences:

>Translated_581_residues
MDHDFSLILTFVGGLAAALLFGLIARKLHLSPLVGYLLAGVAVGPYSPGFVADSHTVEQFAELGVILLMFGVGLHFHLKD
LIAVQKVAVPGAVVQISVATVLGVLVGWMFGWSAISGLVFGMAISVASTVVLTRVLEDNQNLHTPGGHVALGWLVVEDLF
TILLLVLIPAVMEARQSGAGDWGGILSELGWMFVKLALLVALTLFAGKKVIPLVLRYVARTGARDLFTLAVLVIALGVAV
CSAEFFGASMVLGAFLAGMVVGQSDFCARAAAEAMLMRDAFAVLFFVSVGMMFDPMSVGDCWPLALATLGVVMIGKPLAA
YVVVRCLRRPVPLALSVSVALAQVGEFSFILAGIGLMYNILPPDANQAIILAAVVSISLNPILYRQIGPAVKWLQKRGIG
LADPGGVNSMALPAPDARRVVLVGFGPTGRILKRILNDNGVEVIIVEMNIDTVTAIREQGGDIVYGDASQREILRHAGIE
YAESLILSASIPDAKEIVGVALELNPHIDVMIHTKYMRDVDILKEAGASQVFSSESEVALSMAEYFLREGGADDEQIVSE
RQRIRAELDREMPGVSVAGHS
>Mature_581_residues
MDHDFSLILTFVGGLAAALLFGLIARKLHLSPLVGYLLAGVAVGPYSPGFVADSHTVEQFAELGVILLMFGVGLHFHLKD
LIAVQKVAVPGAVVQISVATVLGVLVGWMFGWSAISGLVFGMAISVASTVVLTRVLEDNQNLHTPGGHVALGWLVVEDLF
TILLLVLIPAVMEARQSGAGDWGGILSELGWMFVKLALLVALTLFAGKKVIPLVLRYVARTGARDLFTLAVLVIALGVAV
CSAEFFGASMVLGAFLAGMVVGQSDFCARAAAEAMLMRDAFAVLFFVSVGMMFDPMSVGDCWPLALATLGVVMIGKPLAA
YVVVRCLRRPVPLALSVSVALAQVGEFSFILAGIGLMYNILPPDANQAIILAAVVSISLNPILYRQIGPAVKWLQKRGIG
LADPGGVNSMALPAPDARRVVLVGFGPTGRILKRILNDNGVEVIIVEMNIDTVTAIREQGGDIVYGDASQREILRHAGIE
YAESLILSASIPDAKEIVGVALELNPHIDVMIHTKYMRDVDILKEAGASQVFSSESEVALSMAEYFLREGGADDEQIVSE
RQRIRAELDREMPGVSVAGHS

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=401, Percent_Identity=27.1820448877805, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1786685, Length=551, Percent_Identity=43.557168784029, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1789749, Length=517, Percent_Identity=27.852998065764, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1786232, Length=534, Percent_Identity=28.0898876404494, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 61714; Mature: 61714

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]