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The map label for this gene is spoVD [H]

Identifier: 187735158

GI number: 187735158

Start: 765313

End: 767412

Strand: Direct

Name: spoVD [H]

Synonym: Amuc_0652

Alternate gene names: 187735158

Gene position: 765313-767412 (Clockwise)

Preceding gene: 187735157

Following gene: 187735159

Centisome position: 28.73

GC content: 58.57

Gene sequence:

>2100_bases
ATGATCACGATCACGAAGTCCAGATTTGCCAGAAGAAGCCTCGTCCTGTGCGGCCTGGCGGGCGCGGCGGTCATCTGGCT
GATGTTGTCGCTGGTCAATCTCCAGCTGGTTTCCCCCCGGAAAACGAGCGGCGTTTCCAGCGGCGGCATTATTGAACGGG
AGGTTCTTTTGCCCCAGCGCGGCCGCATCATGGACGCCAATGAGGAAATCCTCACCAGCAACATGCAGAGCTCCGAGCTG
ATTGCGGACGGCTATCATCTGAACGACCCCAAGACCATCAGCTGGGCTCTGGCCTATTCCAAGGCCGTCCATTCCCCGTT
CTGGGAGAAAGCCGCAACGGATAAGGAAAAGGAAAAGCTCGTTTCCGGCTTCCGTAGCAAGATTCTGGGCCAGGCCGCCA
GCAAAAAGGACGGCAGCAAGGAACATAATCTGGCGAAAATCCTGCTGGAAGAGCCTGAAGACGGACCGGAAGGGGTAGAT
ATGGCCAGAAAAAAGCTGGAAGAGCTTTATGAGCCGGAGATGGTGAAAGAATACGTGCAGGCGCACCTGGAATACGCCGC
CAAAGTGATTGCCCCTTTCCTGCCGGACATGAGCGTGCAGGACATCATCAACACGGTGGAAAAAGACGGGGCGATTCCCA
AGAAGCGCATCGTCATTGCCAAAAACCTGTCCGAGGAAAAAGCGGAACTGCTGCGGCAGGCTATCCAGAACGCCCGCGTC
CAGGGGTTCCGTTTTGAGACCTCCTCCAAACGCGTCTATTCCGTGCCGGAATGCATGGTGCATATTCTGGGCTACATCGC
CCAGACGAAGGACAGCGGCCCCCGGCCCATAGCCCTTTCCGGCCTTGAAAAGCAGCTGGACGACCAGCTGCTGGGCCACA
ACGGCATCAGGGAATACCGGAAAGACAGCCGCGGGCGCATCATTCCCTCCGCGGATTCCCGCTTCAAGGATGCCGTGGAC
GGGCTGAACGTGCGCCTGACGGTAAACATGGAATACCAGACGATCGTGGAGGAGGAGCTGGACGCCGCCATCTCTTTTTA
CACGGACCAGACCCACAAACCCCGCGGCTGCATTATTGTGGTGGAACCCAAGACCGGCAGCATTCTGGCGATGGCCAGCC
GGCCCCACTATAATTTAAATACGCGCGAGGGCCTTCAGGAAGGCGCCTACCATTTCGCCGTGCAGTCCCTGTACGAACCC
GGTTCCACCTTTAAAATAGTTTCCGTCACATCCGCCGTGGACAGCGGAAAGGCCACGTTCGACACCATGATCAACTGCAC
CCCTTATCCGGTGCCCGGTTCCCGCCCCGTCACGGACGCCCCCCGTTCCTATGGCGGCCTGACCGTAGCGGGCGTGCTGA
AAAAATCCAGCAACCCGGGCGCCTTCCGCATTGCACTGAAATCGGGTTGGCCCACGTATAAAAAATACTTTGACCTGTAC
GGATTTTCCTCCAAAACGGGTATCGACCTGCCGGGGGAAACCAACAGCCAGTGCCAGGACGGCAGCAATTTTGTCAACTT
TTCCCGCATCAGCTTCGGCTACTCCCTGATGGTGTCCCCCCTGCAGGTCGCCATGGCTTATGCCGCCATAGCCAATGACG
GCGTGCGCATGCGCCCCCGGCTGGTTGACGGCATTTATGTGGATGACAGAAACTTCCAGCCTTCCCCCCCCGTGGAGGTA
TGCCGGGTCATGAGCGTCAAGACGGCCCGGGACCTTCGGAACGCCCTGTTCCACGTTACGGATCTGGACGGGACCGCCAA
AAGAGCGCGGGTTGAAGGCTATAACGTGGGAGGCAAAACCGGAACCGCCCACAAGGTGAAGCCTACAGGCGGCTATTTTG
AAAACCGCTACACCGTCTCCTTTGTAGGAATGCTCCCGGTGGAGGACCCGGCCTTCGTCTGCCTTGTCGTCATTGACGAC
CCCACTTCCAAGCATTGCCATCCCGGAGGCGGAACCGTATGCGCCCCGGTCTTCCAGAAACTGGCCACCCGCCTGGCGGC
CGCCATGAACATTCCTAAGAACGTCCCTTCCGCAGAGGCAAATAAAAAAGCCTCCCGTGCCCAGGCCTCTTCCACCCCAT
CCAAACCGCCGCGCAGATAA

Upstream 100 bases:

>100_bases
TCCAACCTGCAGCCTATCGAGCCCTCAGCCGTAGAATACATTTCTTCCGAAAACGCCTCCCGCATCGCTGCGGCAGGCCA
TTAACTGCGTTGAGCCGTTC

Downstream 100 bases:

>100_bases
TCCCGTCATGAAGCTACTTACCTTACTCAAAGACCTTCCCTCCCATACGCTCACCGGCTCCCCCCAGGTGAAAATCTCCC
ATCTGGAATGCGACAGCCGG

Product: Peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MITITKSRFARRSLVLCGLAGAAVIWLMLSLVNLQLVSPRKTSGVSSGGIIEREVLLPQRGRIMDANEEILTSNMQSSEL
IADGYHLNDPKTISWALAYSKAVHSPFWEKAATDKEKEKLVSGFRSKILGQAASKKDGSKEHNLAKILLEEPEDGPEGVD
MARKKLEELYEPEMVKEYVQAHLEYAAKVIAPFLPDMSVQDIINTVEKDGAIPKKRIVIAKNLSEEKAELLRQAIQNARV
QGFRFETSSKRVYSVPECMVHILGYIAQTKDSGPRPIALSGLEKQLDDQLLGHNGIREYRKDSRGRIIPSADSRFKDAVD
GLNVRLTVNMEYQTIVEEELDAAISFYTDQTHKPRGCIIVVEPKTGSILAMASRPHYNLNTREGLQEGAYHFAVQSLYEP
GSTFKIVSVTSAVDSGKATFDTMINCTPYPVPGSRPVTDAPRSYGGLTVAGVLKKSSNPGAFRIALKSGWPTYKKYFDLY
GFSSKTGIDLPGETNSQCQDGSNFVNFSRISFGYSLMVSPLQVAMAYAAIANDGVRMRPRLVDGIYVDDRNFQPSPPVEV
CRVMSVKTARDLRNALFHVTDLDGTAKRARVEGYNVGGKTGTAHKVKPTGGYFENRYTVSFVGMLPVEDPAFVCLVVIDD
PTSKHCHPGGGTVCAPVFQKLATRLAAAMNIPKNVPSAEANKKASRAQASSTPSKPPRR

Sequences:

>Translated_699_residues
MITITKSRFARRSLVLCGLAGAAVIWLMLSLVNLQLVSPRKTSGVSSGGIIEREVLLPQRGRIMDANEEILTSNMQSSEL
IADGYHLNDPKTISWALAYSKAVHSPFWEKAATDKEKEKLVSGFRSKILGQAASKKDGSKEHNLAKILLEEPEDGPEGVD
MARKKLEELYEPEMVKEYVQAHLEYAAKVIAPFLPDMSVQDIINTVEKDGAIPKKRIVIAKNLSEEKAELLRQAIQNARV
QGFRFETSSKRVYSVPECMVHILGYIAQTKDSGPRPIALSGLEKQLDDQLLGHNGIREYRKDSRGRIIPSADSRFKDAVD
GLNVRLTVNMEYQTIVEEELDAAISFYTDQTHKPRGCIIVVEPKTGSILAMASRPHYNLNTREGLQEGAYHFAVQSLYEP
GSTFKIVSVTSAVDSGKATFDTMINCTPYPVPGSRPVTDAPRSYGGLTVAGVLKKSSNPGAFRIALKSGWPTYKKYFDLY
GFSSKTGIDLPGETNSQCQDGSNFVNFSRISFGYSLMVSPLQVAMAYAAIANDGVRMRPRLVDGIYVDDRNFQPSPPVEV
CRVMSVKTARDLRNALFHVTDLDGTAKRARVEGYNVGGKTGTAHKVKPTGGYFENRYTVSFVGMLPVEDPAFVCLVVIDD
PTSKHCHPGGGTVCAPVFQKLATRLAAAMNIPKNVPSAEANKKASRAQASSTPSKPPRR
>Mature_699_residues
MITITKSRFARRSLVLCGLAGAAVIWLMLSLVNLQLVSPRKTSGVSSGGIIEREVLLPQRGRIMDANEEILTSNMQSSEL
IADGYHLNDPKTISWALAYSKAVHSPFWEKAATDKEKEKLVSGFRSKILGQAASKKDGSKEHNLAKILLEEPEDGPEGVD
MARKKLEELYEPEMVKEYVQAHLEYAAKVIAPFLPDMSVQDIINTVEKDGAIPKKRIVIAKNLSEEKAELLRQAIQNARV
QGFRFETSSKRVYSVPECMVHILGYIAQTKDSGPRPIALSGLEKQLDDQLLGHNGIREYRKDSRGRIIPSADSRFKDAVD
GLNVRLTVNMEYQTIVEEELDAAISFYTDQTHKPRGCIIVVEPKTGSILAMASRPHYNLNTREGLQEGAYHFAVQSLYEP
GSTFKIVSVTSAVDSGKATFDTMINCTPYPVPGSRPVTDAPRSYGGLTVAGVLKKSSNPGAFRIALKSGWPTYKKYFDLY
GFSSKTGIDLPGETNSQCQDGSNFVNFSRISFGYSLMVSPLQVAMAYAAIANDGVRMRPRLVDGIYVDDRNFQPSPPVEV
CRVMSVKTARDLRNALFHVTDLDGTAKRARVEGYNVGGKTGTAHKVKPTGGYFENRYTVSFVGMLPVEDPAFVCLVVIDD
PTSKHCHPGGGTVCAPVFQKLATRLAAAMNIPKNVPSAEANKKASRAQASSTPSKPPRR

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=477, Percent_Identity=31.4465408805031, Blast_Score=199, Evalue=7e-52,
Organism=Escherichia coli, GI1786854, Length=436, Percent_Identity=23.6238532110092, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 76716; Mature: 76716

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITITKSRFARRSLVLCGLAGAAVIWLMLSLVNLQLVSPRKTSGVSSGGIIEREVLLPQR
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCC
GRIMDANEEILTSNMQSSELIADGYHLNDPKTISWALAYSKAVHSPFWEKAATDKEKEKL
CCEECCCHHHHHCCCCCCHHEECCEECCCCCEEEHHHHHHHHHCCCHHHHHCCCHHHHHH
VSGFRSKILGQAASKKDGSKEHNLAKILLEEPEDGPEGVDMARKKLEELYEPEMVKEYVQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
AHLEYAAKVIAPFLPDMSVQDIINTVEKDGAIPKKRIVIAKNLSEEKAELLRQAIQNARV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
QGFRFETSSKRVYSVPECMVHILGYIAQTKDSGPRPIALSGLEKQLDDQLLGHNGIREYR
CCEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCHHHHHH
KDSRGRIIPSADSRFKDAVDGLNVRLTVNMEYQTIVEEELDAAISFYTDQTHKPRGCIIV
HCCCCCCCCCCCHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VEPKTGSILAMASRPHYNLNTREGLQEGAYHFAVQSLYEPGSTFKIVSVTSAVDSGKATF
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHCCCCCCH
DTMINCTPYPVPGSRPVTDAPRSYGGLTVAGVLKKSSNPGAFRIALKSGWPTYKKYFDLY
HHEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEEEECCCCHHHHHHHHC
GFSSKTGIDLPGETNSQCQDGSNFVNFSRISFGYSLMVSPLQVAMAYAAIANDGVRMRPR
CCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCE
LVDGIYVDDRNFQPSPPVEVCRVMSVKTARDLRNALFHVTDLDGTAKRARVEGYNVGGKT
EECEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHEECCCCCCCCC
GTAHKVKPTGGYFENRYTVSFVGMLPVEDPAFVCLVVIDDPTSKHCHPGGGTVCAPVFQK
CCCEEECCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHH
LATRLAAAMNIPKNVPSAEANKKASRAQASSTPSKPPRR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MITITKSRFARRSLVLCGLAGAAVIWLMLSLVNLQLVSPRKTSGVSSGGIIEREVLLPQR
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCC
GRIMDANEEILTSNMQSSELIADGYHLNDPKTISWALAYSKAVHSPFWEKAATDKEKEKL
CCEECCCHHHHHCCCCCCHHEECCEECCCCCEEEHHHHHHHHHCCCHHHHHCCCHHHHHH
VSGFRSKILGQAASKKDGSKEHNLAKILLEEPEDGPEGVDMARKKLEELYEPEMVKEYVQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
AHLEYAAKVIAPFLPDMSVQDIINTVEKDGAIPKKRIVIAKNLSEEKAELLRQAIQNARV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
QGFRFETSSKRVYSVPECMVHILGYIAQTKDSGPRPIALSGLEKQLDDQLLGHNGIREYR
CCEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCHHHHHH
KDSRGRIIPSADSRFKDAVDGLNVRLTVNMEYQTIVEEELDAAISFYTDQTHKPRGCIIV
HCCCCCCCCCCCHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VEPKTGSILAMASRPHYNLNTREGLQEGAYHFAVQSLYEPGSTFKIVSVTSAVDSGKATF
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHCCCCCCH
DTMINCTPYPVPGSRPVTDAPRSYGGLTVAGVLKKSSNPGAFRIALKSGWPTYKKYFDLY
HHEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEEEECCCCHHHHHHHHC
GFSSKTGIDLPGETNSQCQDGSNFVNFSRISFGYSLMVSPLQVAMAYAAIANDGVRMRPR
CCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCE
LVDGIYVDDRNFQPSPPVEVCRVMSVKTARDLRNALFHVTDLDGTAKRARVEGYNVGGKT
EECEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHEECCCCCCCCC
GTAHKVKPTGGYFENRYTVSFVGMLPVEDPAFVCLVVIDDPTSKHCHPGGGTVCAPVFQK
CCCEEECCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHH
LATRLAAAMNIPKNVPSAEANKKASRAQASSTPSKPPRR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]