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The map label for this gene is lysN [H]

Identifier: 186476870

GI number: 186476870

Start: 2375685

End: 2376881

Strand: Direct

Name: lysN [H]

Synonym: Bphy_2117

Alternate gene names: 186476870

Gene position: 2375685-2376881 (Clockwise)

Preceding gene: 186476869

Following gene: 186476871

Centisome position: 68.28

GC content: 64.66

Gene sequence:

>1197_bases
ATGAATCAAAGCGACCTCAATGCCCCGACCTGGCAATTGTCCGAACGCGCTCGCAAGCTGACCAGCTCGGCGATCCGCGA
AATCCTGAAGGTCACCGAGCGGCCCGAGGTCATTTCGTTCGCGGGCGGTCTGCCGTCGCCGGCCACTTTCCCGGCCGAGG
AAATGCGCGCCGCCAGCGACCGCATCCTGCGCGACTCGCCCGCTGCCGCGCTCCAGTACAGCGCGACGGAAGGCTATCTT
CCATTGCGCGAATGGGTTGCGCAGCGCTATTCGGCGAATGGCGCGCAGATCCGTCCTTCGCAGGTGCTGATCACCACCGG
CTCGCAGCAGGCGCTCGATCTGCTCGGCAAGGTGCTCGTCTGCCCGCAAAGCCCGGTGCTGGTCGAAACGCCGACGTATC
TCGGCGCGCTGCAGTCGTTCTCGATGTACGAGCCGCACTACGTGCAGGTGCCGACCGACGATAGCGGCCTGATTCCCGAA
GGCCTCACGCCCGAACTGACGAAGGGTGCGCGCCTGCTGTACGCGCAGCCGAACTTCCAGAATCCGACGGGACGCCGCCT
GCCCGTCGAGCGCCGCCGCGCGCTCGCCGAATTCGCGAAGTCGGCGCCGTTCCCGGTGCTGGAAGACGATCCATACGGCG
CGCTCGACTACAAGGGAGAACCGCTGCCGACCATGCTGTCGATGGCGCCCGATCACATCGTGCATCTCGGCTCGTTCTCG
AAAGTGCTCGCGCCGGGTCTGCGCATCGGCTACATCATTGCGCCCGAAGAACTGCACTTCAAGCTCGTGCAGGCCAAGCA
GGCAACCGACCTGCACACGCCGAGCTTCACGCAGCGCATCGTGCACGAAGTCGTGAAGGACGGCTTCCTCGATACGCATG
TGCCGAAGATCCGCGCGCTGTATCGCGACCAGTGCGAAGCGATGCTCGGCTCGCTCGAGCGCTACATGCCCGAAGGCGTG
ACATGGAACCGACCAGAAGGCGGCATGTTCATCTGGGTATCGCTGCCGAAGCACATCGACTCGATGAAGCTGCTCGAAGA
AGCCGTCGCGCAGAATGTGGCGTTCGTGCCGGGCGGTCCGTTCTTCGCCAACCAGGCACAGCACAATACGCTGCGCCTGT
CGTTCGTGACCGTGCCGCCCGCAAAAATCGACGAAGGCGTGGCGCGCCTCGCGCAACTCATCCGCGCACGCGTTTGA

Upstream 100 bases:

>100_bases
TACATACGGCCGTACGGCCGGTTCGCGCCGCCTGACGAGTTCGCGCGATAATCCCTGTTTTTGACCGACCACCTGATCCT
GCTACACCGACGAGGAGACC

Downstream 100 bases:

>100_bases
GACATGCCGTAGGATGCGCAACACGCATCGCTGACATCGTGCGCGCCGCCGGCATCTGTTTGGCTGCGCGCACGCTGAAC
CACTCTTTCCATTCATCGAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNQSDLNAPTWQLSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAEEMRAASDRILRDSPAAALQYSATEGYL
PLREWVAQRYSANGAQIRPSQVLITTGSQQALDLLGKVLVCPQSPVLVETPTYLGALQSFSMYEPHYVQVPTDDSGLIPE
GLTPELTKGARLLYAQPNFQNPTGRRLPVERRRALAEFAKSAPFPVLEDDPYGALDYKGEPLPTMLSMAPDHIVHLGSFS
KVLAPGLRIGYIIAPEELHFKLVQAKQATDLHTPSFTQRIVHEVVKDGFLDTHVPKIRALYRDQCEAMLGSLERYMPEGV
TWNRPEGGMFIWVSLPKHIDSMKLLEEAVAQNVAFVPGGPFFANQAQHNTLRLSFVTVPPAKIDEGVARLAQLIRARV

Sequences:

>Translated_398_residues
MNQSDLNAPTWQLSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAEEMRAASDRILRDSPAAALQYSATEGYL
PLREWVAQRYSANGAQIRPSQVLITTGSQQALDLLGKVLVCPQSPVLVETPTYLGALQSFSMYEPHYVQVPTDDSGLIPE
GLTPELTKGARLLYAQPNFQNPTGRRLPVERRRALAEFAKSAPFPVLEDDPYGALDYKGEPLPTMLSMAPDHIVHLGSFS
KVLAPGLRIGYIIAPEELHFKLVQAKQATDLHTPSFTQRIVHEVVKDGFLDTHVPKIRALYRDQCEAMLGSLERYMPEGV
TWNRPEGGMFIWVSLPKHIDSMKLLEEAVAQNVAFVPGGPFFANQAQHNTLRLSFVTVPPAKIDEGVARLAQLIRARV
>Mature_398_residues
MNQSDLNAPTWQLSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAEEMRAASDRILRDSPAAALQYSATEGYL
PLREWVAQRYSANGAQIRPSQVLITTGSQQALDLLGKVLVCPQSPVLVETPTYLGALQSFSMYEPHYVQVPTDDSGLIPE
GLTPELTKGARLLYAQPNFQNPTGRRLPVERRRALAEFAKSAPFPVLEDDPYGALDYKGEPLPTMLSMAPDHIVHLGSFS
KVLAPGLRIGYIIAPEELHFKLVQAKQATDLHTPSFTQRIVHEVVKDGFLDTHVPKIRALYRDQCEAMLGSLERYMPEGV
TWNRPEGGMFIWVSLPKHIDSMKLLEEAVAQNVAFVPGGPFFANQAQHNTLRLSFVTVPPAKIDEGVARLAQLIRARV

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=407, Percent_Identity=31.9410319410319, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI33469970, Length=407, Percent_Identity=31.9410319410319, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=26.7716535433071, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790797, Length=321, Percent_Identity=28.6604361370716, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI48994949, Length=395, Percent_Identity=25.0632911392405, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321236, Length=485, Percent_Identity=22.680412371134, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321000, Length=258, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21356535, Length=392, Percent_Identity=25.2551020408163, Blast_Score=126, Evalue=3e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 44025; Mature: 44025

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSDLNAPTWQLSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAEEMRAASD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RILRDSPAAALQYSATEGYLPLREWVAQRYSANGAQIRPSQVLITTGSQQALDLLGKVLV
HHHCCCCCHHEEECCCCCCCHHHHHHHHHHCCCCCEECCCEEEEECCCHHHHHHHHHHEE
CPQSPVLVETPTYLGALQSFSMYEPHYVQVPTDDSGLIPEGLTPELTKGARLLYAQPNFQ
CCCCCEEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
NPTGRRLPVERRRALAEFAKSAPFPVLEDDPYGALDYKGEPLPTMLSMAPDHIVHLGSFS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEECCCHH
KVLAPGLRIGYIIAPEELHFKLVQAKQATDLHTPSFTQRIVHEVVKDGFLDTHVPKIRAL
HHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
YRDQCEAMLGSLERYMPEGVTWNRPEGGMFIWVSLPKHIDSMKLLEEAVAQNVAFVPGGP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEECCCCC
FFANQAQHNTLRLSFVTVPPAKIDEGVARLAQLIRARV
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQSDLNAPTWQLSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAEEMRAASD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RILRDSPAAALQYSATEGYLPLREWVAQRYSANGAQIRPSQVLITTGSQQALDLLGKVLV
HHHCCCCCHHEEECCCCCCCHHHHHHHHHHCCCCCEECCCEEEEECCCHHHHHHHHHHEE
CPQSPVLVETPTYLGALQSFSMYEPHYVQVPTDDSGLIPEGLTPELTKGARLLYAQPNFQ
CCCCCEEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
NPTGRRLPVERRRALAEFAKSAPFPVLEDDPYGALDYKGEPLPTMLSMAPDHIVHLGSFS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEECCCHH
KVLAPGLRIGYIIAPEELHFKLVQAKQATDLHTPSFTQRIVHEVVKDGFLDTHVPKIRAL
HHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
YRDQCEAMLGSLERYMPEGVTWNRPEGGMFIWVSLPKHIDSMKLLEEAVAQNVAFVPGGP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEECCCCC
FFANQAQHNTLRLSFVTVPPAKIDEGVARLAQLIRARV
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA