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The map label for this gene is yafC [H]

Identifier: 186476004

GI number: 186476004

Start: 1396645

End: 1397511

Strand: Reverse

Name: yafC [H]

Synonym: Bphy_1245

Alternate gene names: 186476004

Gene position: 1397511-1396645 (Counterclockwise)

Preceding gene: 186476007

Following gene: 186476003

Centisome position: 40.17

GC content: 64.24

Gene sequence:

>867_bases
ATGGAAGTGTTCGTGGCTGTTGTCGAAGCGGGCAGCCTCACGGCGGCCGCGGAGCGCTTCGACCTGTCGTCAGCGATGGT
CGGCAAGCATATCCGCTCGCTCGAAACGCAGCTTTCCACGCGGCTGCTCACGCGCACGACGCGCCGCCAAAGCCTGACTG
AAATCGGCCGTCAGTATTACGAGCAATGCCGGCGCATTCTCGCCGATGTGAAGGCTGCGGAGTCGCTCGCGGAAGCGATG
ACCTCCGCGCCGCGCGGCACGCTGAAGATCACCGTGCCACTCACCTATGGCGTCGAGCTGTTCTCGCCGGCAATGACGGA
CTATCTGAACCTCTACCCCGAAGTCAGTCTCGAACTCGATCTGTCGAACCGCATCTTCGATCTCGTCGATGAAGGCTTCG
ACGCGGCCGTGCGCATCGGGCGGCTGCCGGATTCGAGCCTCGTCGCGAGACCGCTCAAACCTTACCGGATGCGTGCGTGC
GCGTCGCCCTCGTATCTGCAACGCATGGGCACGCCGGCGACGCCTGCCGATCTCGTTCATCACGAATGCCTCGGCTTTCT
GCATTGGGGACGCGAAGGGCTGTGGCGACTCGGCGGCGATGCCGAGGCGGACTATCAGTTGCGCCCGGGCCGCTTTCGCG
CGAACAACGGACAGGCGCTGAAGATGGCAGCACTGCGCGGCTTCGGTCTCGTGCTGCAACCGGAAGCGCTACTCGCCCGG
GAGATCGGGCGAGGTGAGCTCGTGTCCGTGCTCGAAGACTATCTGCCGGAGGGCGCGCCTGTGCATCTGATCTATCCGCG
CGACCGCCAACCGACGCCGAAGCTCACCACGTTCATCGACTTCGTGATCGAGCGCTTCGGCGTGTAA

Upstream 100 bases:

>100_bases
GTGCATTATTAGTAACACGGTATCGCTTTATTGCGTCTCTATTGCGACAACTGCTTACAACCGAAACGAACGGAAATAGC
CGGTGGATAAATTCGTCAGC

Downstream 100 bases:

>100_bases
CGTTGCTGATCCACGCGACGACGCGCGCTGGCTCAATATGTGCAAGCTGCATGTATTCGCACATGCACGGGCAGGGCGCA
TAATCCGCGTCATCGGCTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MEVFVAVVEAGSLTAAAERFDLSSAMVGKHIRSLETQLSTRLLTRTTRRQSLTEIGRQYYEQCRRILADVKAAESLAEAM
TSAPRGTLKITVPLTYGVELFSPAMTDYLNLYPEVSLELDLSNRIFDLVDEGFDAAVRIGRLPDSSLVARPLKPYRMRAC
ASPSYLQRMGTPATPADLVHHECLGFLHWGREGLWRLGGDAEADYQLRPGRFRANNGQALKMAALRGFGLVLQPEALLAR
EIGRGELVSVLEDYLPEGAPVHLIYPRDRQPTPKLTTFIDFVIERFGV

Sequences:

>Translated_288_residues
MEVFVAVVEAGSLTAAAERFDLSSAMVGKHIRSLETQLSTRLLTRTTRRQSLTEIGRQYYEQCRRILADVKAAESLAEAM
TSAPRGTLKITVPLTYGVELFSPAMTDYLNLYPEVSLELDLSNRIFDLVDEGFDAAVRIGRLPDSSLVARPLKPYRMRAC
ASPSYLQRMGTPATPADLVHHECLGFLHWGREGLWRLGGDAEADYQLRPGRFRANNGQALKMAALRGFGLVLQPEALLAR
EIGRGELVSVLEDYLPEGAPVHLIYPRDRQPTPKLTTFIDFVIERFGV
>Mature_288_residues
MEVFVAVVEAGSLTAAAERFDLSSAMVGKHIRSLETQLSTRLLTRTTRRQSLTEIGRQYYEQCRRILADVKAAESLAEAM
TSAPRGTLKITVPLTYGVELFSPAMTDYLNLYPEVSLELDLSNRIFDLVDEGFDAAVRIGRLPDSSLVARPLKPYRMRAC
ASPSYLQRMGTPATPADLVHHECLGFLHWGREGLWRLGGDAEADYQLRPGRFRANNGQALKMAALRGFGLVLQPEALLAR
EIGRGELVSVLEDYLPEGAPVHLIYPRDRQPTPKLTTFIDFVIERFGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=36.9337979094077, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI145693193, Length=284, Percent_Identity=31.6901408450704, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=32.8671328671329, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=30.2083333333333, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.1418685121107, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787589, Length=281, Percent_Identity=30.6049822064057, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787128, Length=281, Percent_Identity=28.4697508896797, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786448, Length=292, Percent_Identity=23.6301369863014, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789173, Length=290, Percent_Identity=23.7931034482759, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=23.3108108108108, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790011, Length=263, Percent_Identity=23.1939163498099, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787879, Length=150, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=30.8333333333333, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32080; Mature: 32080

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVFVAVVEAGSLTAAAERFDLSSAMVGKHIRSLETQLSTRLLTRTTRRQSLTEIGRQYY
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQCRRILADVKAAESLAEAMTSAPRGTLKITVPLTYGVELFSPAMTDYLNLYPEVSLELD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEE
LSNRIFDLVDEGFDAAVRIGRLPDSSLVARPLKPYRMRACASPSYLQRMGTPATPADLVH
CHHHHHHHHHCCHHHHEEECCCCCHHHHHCCCCHHHHHHCCCHHHHHHCCCCCCHHHHHH
HECLGFLHWGREGLWRLGGDAEADYQLRPGRFRANNGQALKMAALRGFGLVLQPEALLAR
HHHHHHHHHCCHHHEECCCCCCCCCEECCCEEECCCCCEEEHHHHHCCCEEECCHHHHHH
EIGRGELVSVLEDYLPEGAPVHLIYPRDRQPTPKLTTFIDFVIERFGV
HCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVFVAVVEAGSLTAAAERFDLSSAMVGKHIRSLETQLSTRLLTRTTRRQSLTEIGRQYY
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQCRRILADVKAAESLAEAMTSAPRGTLKITVPLTYGVELFSPAMTDYLNLYPEVSLELD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEE
LSNRIFDLVDEGFDAAVRIGRLPDSSLVARPLKPYRMRACASPSYLQRMGTPATPADLVH
CHHHHHHHHHCCHHHHEEECCCCCHHHHHCCCCHHHHHHCCCHHHHHHCCCCCCHHHHHH
HECLGFLHWGREGLWRLGGDAEADYQLRPGRFRANNGQALKMAALRGFGLVLQPEALLAR
HHHHHHHHHCCHHHEECCCCCCCCCEECCCEEECCCCCEEEHHHHHCCCEEECCHHHHHH
EIGRGELVSVLEDYLPEGAPVHLIYPRDRQPTPKLTTFIDFVIERFGV
HCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]