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The map label for this gene is lrp [C]

Identifier: 186476003

GI number: 186476003

Start: 1396036

End: 1396494

Strand: Reverse

Name: lrp [C]

Synonym: Bphy_1244

Alternate gene names: 186476003

Gene position: 1396494-1396036 (Counterclockwise)

Preceding gene: 186476004

Following gene: 186476002

Centisome position: 40.14

GC content: 62.75

Gene sequence:

>459_bases
ATGAGACCACCGCGCCTCGATCAACTCGACGAACTCGATCGCAACCTCGTTGCGCTGTTGCAAGCCAATGCGCGCGAAAG
CGTCGCGAATCTCGCGCGGCAACTGGGTGTCGCGCGCACGACCGTGATCGCGCGCATCGCGCGGCTGGAAAAGACCCATG
TGATTGCGGGTTACAGCGTGCGGCTCGGGCAGGACGTGCTCGACGCGAGCATGCACGCGTACGTGGGCATCATCATCGCG
CCGAAGTATGGCCCGGATGTCCTGAAGAAGCTCAACCGGATGCCCGAAGTGCAACTGTTGTGCGCGGTGAGCGGCGAGTT
CGATTACGTCGCCTGGCTGCGCGCCGATTCGCCCGAGCGTCTCAACGATCTGCTCGATCAGATTGGTGGACTGGCGGGCG
TCGAACGCACCACGACGTCGATCATCCTGTCGCGCAAGATCGATCGTGGCATGACGTGA

Upstream 100 bases:

>100_bases
ATGTATTCGCACATGCACGGGCAGGGCGCATAATCCGCGTCATCGGCTCGTCACATCGGGCGGGCTTTCACTTTCAAACT
CCACCTTTGATCTGCAAACG

Downstream 100 bases:

>100_bases
TGGGGCGCTAATTCGCGGCAGCGATGCGGGTCTCCTGGACGCGGTTTTGTGCCGTCTCGACGAATCGTCGGAGCGATACG
TCGTTTAGACGAAAATCGTG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRPPRLDQLDELDRNLVALLQANARESVANLARQLGVARTTVIARIARLEKTHVIAGYSVRLGQDVLDASMHAYVGIIIA
PKYGPDVLKKLNRMPEVQLLCAVSGEFDYVAWLRADSPERLNDLLDQIGGLAGVERTTTSIILSRKIDRGMT

Sequences:

>Translated_152_residues
MRPPRLDQLDELDRNLVALLQANARESVANLARQLGVARTTVIARIARLEKTHVIAGYSVRLGQDVLDASMHAYVGIIIA
PKYGPDVLKKLNRMPEVQLLCAVSGEFDYVAWLRADSPERLNDLLDQIGGLAGVERTTTSIILSRKIDRGMT
>Mature_152_residues
MRPPRLDQLDELDRNLVALLQANARESVANLARQLGVARTTVIARIARLEKTHVIAGYSVRLGQDVLDASMHAYVGIIIA
PKYGPDVLKKLNRMPEVQLLCAVSGEFDYVAWLRADSPERLNDLLDQIGGLAGVERTTTSIILSRKIDRGMT

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=141, Percent_Identity=32.6241134751773, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=27.972027972028, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 16804; Mature: 16804

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPRLDQLDELDRNLVALLQANARESVANLARQLGVARTTVIARIARLEKTHVIAGYSV
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHH
RLGQDVLDASMHAYVGIIIAPKYGPDVLKKLNRMPEVQLLCAVSGEFDYVAWLRADSPER
HHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHH
LNDLLDQIGGLAGVERTTTSIILSRKIDRGMT
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRPPRLDQLDELDRNLVALLQANARESVANLARQLGVARTTVIARIARLEKTHVIAGYSV
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHH
RLGQDVLDASMHAYVGIIIAPKYGPDVLKKLNRMPEVQLLCAVSGEFDYVAWLRADSPER
HHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHH
LNDLLDQIGGLAGVERTTTSIILSRKIDRGMT
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA