Click here to switch to the map view.

The map label for this gene is lmrA [H]

Identifier: 183222765

GI number: 183222765

Start: 3543629

End: 3544288

Strand: Direct

Name: lmrA [H]

Synonym: LEPBI_I3424

Alternate gene names: 183222765

Gene position: 3543629-3544288 (Clockwise)

Preceding gene: 183222763

Following gene: 183222766

Centisome position: 98.44

GC content: 41.67

Gene sequence:

>660_bases
ATGAATCCATCCCTTTTGTTTGGAAAGGGAGAGTTTATAGATTTTTATGTTGACCGGTCTATTATTAATTCAGCCAATGG
GTTTGTGGGCAAAAAAGGATTCGATACCAAACAAAAGATGATCGAGGTGATGGCCTCTCTTTTGGAAGAAGAAGGATATG
AAAGGGCAGGTCTCTCCGAACTCGGGAAAGAAACGGGGACACCGAAAGGTTCTCTCTACTTTCACTTTCCAGGAGGAAAG
GATGAACTGACAAGCCTTGCCATTCTGTACTCGGGAAAACAATTGAATGATTTTTTTCTCAGTGTATTTGGGAATTGTGA
TTCACCACAACAGGCCATTAAACAAGTGTTCCATGCTCTAGAGGAAAGAATTGTGACAAGTAATTTCCAAAAAGGTTGCC
CCATCGCCACAACTGCCATGGAGACCGCTGGTAAAACGACTATTGTTTCGGATGCATGTAAAGACGTGTATGCCCTATGG
ATCAAAACCTTTGAAACCTATTTGGTGGGAAGCGGTTACACATCACGCCTTGCCAAAACTTTATCCCTTTCGATTTTCGC
TTTATGGGAAGGATCTTTATTACTTTCCAAATTACAAAAATCGGCCGAGCCATTGCGGATGGCAGAAAAAACCGCTGAGA
GTTTGTTAAAACAAACTTAA

Upstream 100 bases:

>100_bases
ATGGCTTCTTATTGATCATACTTCGTCCCGAAATCCGTACTATTAAGTTTATCGGCGAAGTCGGAAAAAAACAATGAGAT
TTATTCTCTAGGAAAATCGG

Downstream 100 bases:

>100_bases
ATGGAAAAACAAAACGATTTTTGATGATCACTCTCTCGCACTAAAAATTTAAAAAAGGACCCTCACACATGAAATCCATT
TCTAAAAAGAAAATTTTCGC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MNPSLLFGKGEFIDFYVDRSIINSANGFVGKKGFDTKQKMIEVMASLLEEEGYERAGLSELGKETGTPKGSLYFHFPGGK
DELTSLAILYSGKQLNDFFLSVFGNCDSPQQAIKQVFHALEERIVTSNFQKGCPIATTAMETAGKTTIVSDACKDVYALW
IKTFETYLVGSGYTSRLAKTLSLSIFALWEGSLLLSKLQKSAEPLRMAEKTAESLLKQT

Sequences:

>Translated_219_residues
MNPSLLFGKGEFIDFYVDRSIINSANGFVGKKGFDTKQKMIEVMASLLEEEGYERAGLSELGKETGTPKGSLYFHFPGGK
DELTSLAILYSGKQLNDFFLSVFGNCDSPQQAIKQVFHALEERIVTSNFQKGCPIATTAMETAGKTTIVSDACKDVYALW
IKTFETYLVGSGYTSRLAKTLSLSIFALWEGSLLLSKLQKSAEPLRMAEKTAESLLKQT
>Mature_219_residues
MNPSLLFGKGEFIDFYVDRSIINSANGFVGKKGFDTKQKMIEVMASLLEEEGYERAGLSELGKETGTPKGSLYFHFPGGK
DELTSLAILYSGKQLNDFFLSVFGNCDSPQQAIKQVFHALEERIVTSNFQKGCPIATTAMETAGKTTIVSDACKDVYALW
IKTFETYLVGSGYTSRLAKTLSLSIFALWEGSLLLSKLQKSAEPLRMAEKTAESLLKQT

Specific function: Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24117; Mature: 24117

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSLLFGKGEFIDFYVDRSIINSANGFVGKKGFDTKQKMIEVMASLLEEEGYERAGLSE
CCCCEEECCCCEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
LGKETGTPKGSLYFHFPGGKDELTSLAILYSGKQLNDFFLSVFGNCDSPQQAIKQVFHAL
HHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
EERIVTSNFQKGCPIATTAMETAGKTTIVSDACKDVYALWIKTFETYLVGSGYTSRLAKT
HHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSLSIFALWEGSLLLSKLQKSAEPLRMAEKTAESLLKQT
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPSLLFGKGEFIDFYVDRSIINSANGFVGKKGFDTKQKMIEVMASLLEEEGYERAGLSE
CCCCEEECCCCEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
LGKETGTPKGSLYFHFPGGKDELTSLAILYSGKQLNDFFLSVFGNCDSPQQAIKQVFHAL
HHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
EERIVTSNFQKGCPIATTAMETAGKTTIVSDACKDVYALWIKTFETYLVGSGYTSRLAKT
HHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSLSIFALWEGSLLLSKLQKSAEPLRMAEKTAESLLKQT
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]