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The map label for this gene is pepN2 [H]

Identifier: 183222759

GI number: 183222759

Start: 3537397

End: 3540039

Strand: Direct

Name: pepN2 [H]

Synonym: LEPBI_I3417

Alternate gene names: 183222759

Gene position: 3537397-3540039 (Clockwise)

Preceding gene: 183222758

Following gene: 183222760

Centisome position: 98.27

GC content: 36.89

Gene sequence:

>2643_bases
ATGAAACAAACACTTGCCATTCTCATCATTGGATTTTTATTAATTTTCCAACACTGTCGTTTGACAAAACCCAATTATCA
CCTAACGTTACAAGAAGCCGAATATCGCTATGAAACAATTGAAAACATTAAGTACAATTTAGACATTCAATTATCAACTA
AGGATAGTTTTACGGGAAAAGTGGACATTCAATTTGTTGGGAAAAGAATCCGCGACTTACGATTGGATTATTTCCAAGGT
GAAATCAAATCGATTGTCTTCAATGATGAACCACTGACCCAATTTGAATATAAAAACGGACAAGTGCAGTTGCCTTCAGA
TCGAATGATGATTGGAAACAATTCGCTTTCCATTAGATTCGAAACTCCTTTTGCCAAAACGGGGAATGGCCTACACAAAT
TTTTGGACCCCGATGACAAAGAAACCTATATCTACTCCCAATTTGAAGCCTTTCACGCGAACAAAATGTTTCCTTGTTTT
GACCAACCCGATTTAAAAGCGACGTTCCAACTGAGTGTAACGGCTCCTAAAAACTGGAAGGTGATCTCTACCACTCTTCC
AACTTCAGAAACAAAAACTGAAAATCCAGAGGAAGTGTTACACCAATTCCCTGAATCTAAAAAAATCTCTACGTATGTGT
TTTCCTTACACGCAGGACCCTACCAAGTTTGGGAAGACAGTTACGAATCCATCCCACTTCGATTGTTTGTTCGAAAATCA
TTAGCAAAGTACATTGATCCCAAAGATTGGTTTTTGTTTACTAAAGATGGATTTGCGTTTTTTAATTCCTATTTTGGAAT
CCCATATCCGTTCCAAAAATATGATCAAATCATTGTACCTGAATTTAATTTTGGAGCGATGGAAAATGTAGCGGCCGTTA
CATTCTCAGAACGATTTGTTTCTCGCTCACCGATGACACGAAACCAAAGAGAAAACCTTTCGGATGTGATTTTACACGAA
ATGGCTCATATGTGGTTTGGAAACTTAGTCACAATGAAGTGGTGGAATGGTCTATGGTTAAACGAAAGTTTTGCAACCTA
TATGGCAAGTTTGGCCCAAGCTAAAAATTCAGAGTTCCAAGAAACCTGGATTAGTTTTTTTGAAAAAATGAAACAGTGGG
CTTATGAAGAAGATAGTTTCAGCACAAACCATCCAGTTGAAGCAAAGGTAAATGATACAGAAGAAGCGTTCACCCAGTTT
GATGGGATCACATATGGTAAAGGTGCTTCTGTCTTAAAACAATTGGTATTTTTTATCGGAGAGGAAAGTTTCCAAAAAGG
AGTTCAAAATTATTTAAGAAAGTATTCCTACTCCAATTCCACCCTGGTAGACTTTTTAAAGGAACTGGAATTTGCCAGTG
GTTTCTCTATGAAAAAATGGTCGAAAGATTGGTTAGAAACCAAAGGAACCAATCAAATTGAACTCACAACGATTTGTGCA
GACAACCATCTCTATGGAAAAATTGTCCAATCCGCTCCTGGCCCTGAAAACAAACTCCGAGATCACAAAACTGTCCTTGG
TCTTTACTTTTTTGATCGATCCAACAAACAAATATCATACGAAGAATTCCCTGTCGTATATTCTGGCCGATCAAGCCAAG
CGATCCTGCAAGTAAAATCATGTCCAGATTATGTATTCATCAATGCAGAAGATCATGACTTTGCCATTTGGAGTTGGACT
TCTGTGAACAAAGACAATTTAGAATTTGTCTTAGAGTTTGATAATGATCCTATGCGAAAACTCATTTTATGGACAGACTA
TTTTCGACAAGTTTCCTTAGCAAATCTCAGTTTTGATGAATTCAAAGAAACTGCCATTCGACTTTACCCAATGGAAACCG
ATACCAAAATCAAACGTTGGCTCTTATCAAGGCTCACATCAGATACTGGTTCTTCCTATTTCACAAGTCGATTTTGGTTT
CCTGAATCCAAACGAAATAACCACTTAGACTCTTTACAAAATTTCATCTTATCTGAGTTAACGAAAGCAAAGGCCGGAAG
TGATGAACAAAAGTATCTGTTCCTTTCACTGATCGATTCAAGTTTTACCGAATCCAGTCAGAAAAGACTGTATGAAATTT
TGGAGAATAAACTCAGTTTTCCAGGTTTGAAACTGGACCAAGACTTACGTTGGAATATGATCGTAAAGTTAAGTTCCCTT
GCAATTGACCGAAACAAAATCCAAACAATGATCGATCGTGAAAAAAAATTAGATCCATCGAACCGTGGTGTGAATTCCAG
TTTGGCGGCGGAAGCGGCAGAACCAAATCCCAAGATCAAAGACAAATGGATCCAAATTTTACTCAATCCGAAAGCAAGTG
ATTACTCTTCTTCAACTTTACGAGTGGTTTCCTATTCTTTATTTCCAGAACACCAAAAAGGGATCCAACTCCAATTTTTA
GATACATACTTTGCTGCTTTGGACAAGTTCCAACATACGGATGACGAAAACTATTTGGATGCGTTTGCAAAAAGTTTAGC
TCCTGATTTTTGTACGGATGAAACATTATTGATTCTAAAAAAATTCACAAACAACCATCCAAAATTACCTGCATCCGTTA
AAAAAACTTTGTGGAAACAAATTGATTCGGAAAAGAGGTGTATCCAAATCAAAAATAAACACAAAGATTTAATTTTAGAA
TAA

Upstream 100 bases:

>100_bases
ATTGGTGGAAAATACTTTCCAGAACCAGAATGGAAAAATCGAAGTTCTATGGACTGGGCCATTTTATACCGCAATTTTCA
ACCGTAATTAGGGAGATACT

Downstream 100 bases:

>100_bases
AGGATCTAACTTTGGATCGAAAAAAATGTAATCTATTTTTGTTACTGATTTTTTTTCAACTAACATCGGTCAGCTGTGCA
AACCCGGGTTTTGGTCCAAG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alanine aminopeptidase; Lysyl aminopeptidase; Lys-AP [H]

Number of amino acids: Translated: 880; Mature: 880

Protein sequence:

>880_residues
MKQTLAILIIGFLLIFQHCRLTKPNYHLTLQEAEYRYETIENIKYNLDIQLSTKDSFTGKVDIQFVGKRIRDLRLDYFQG
EIKSIVFNDEPLTQFEYKNGQVQLPSDRMMIGNNSLSIRFETPFAKTGNGLHKFLDPDDKETYIYSQFEAFHANKMFPCF
DQPDLKATFQLSVTAPKNWKVISTTLPTSETKTENPEEVLHQFPESKKISTYVFSLHAGPYQVWEDSYESIPLRLFVRKS
LAKYIDPKDWFLFTKDGFAFFNSYFGIPYPFQKYDQIIVPEFNFGAMENVAAVTFSERFVSRSPMTRNQRENLSDVILHE
MAHMWFGNLVTMKWWNGLWLNESFATYMASLAQAKNSEFQETWISFFEKMKQWAYEEDSFSTNHPVEAKVNDTEEAFTQF
DGITYGKGASVLKQLVFFIGEESFQKGVQNYLRKYSYSNSTLVDFLKELEFASGFSMKKWSKDWLETKGTNQIELTTICA
DNHLYGKIVQSAPGPENKLRDHKTVLGLYFFDRSNKQISYEEFPVVYSGRSSQAILQVKSCPDYVFINAEDHDFAIWSWT
SVNKDNLEFVLEFDNDPMRKLILWTDYFRQVSLANLSFDEFKETAIRLYPMETDTKIKRWLLSRLTSDTGSSYFTSRFWF
PESKRNNHLDSLQNFILSELTKAKAGSDEQKYLFLSLIDSSFTESSQKRLYEILENKLSFPGLKLDQDLRWNMIVKLSSL
AIDRNKIQTMIDREKKLDPSNRGVNSSLAAEAAEPNPKIKDKWIQILLNPKASDYSSSTLRVVSYSLFPEHQKGIQLQFL
DTYFAALDKFQHTDDENYLDAFAKSLAPDFCTDETLLILKKFTNNHPKLPASVKKTLWKQIDSEKRCIQIKNKHKDLILE

Sequences:

>Translated_880_residues
MKQTLAILIIGFLLIFQHCRLTKPNYHLTLQEAEYRYETIENIKYNLDIQLSTKDSFTGKVDIQFVGKRIRDLRLDYFQG
EIKSIVFNDEPLTQFEYKNGQVQLPSDRMMIGNNSLSIRFETPFAKTGNGLHKFLDPDDKETYIYSQFEAFHANKMFPCF
DQPDLKATFQLSVTAPKNWKVISTTLPTSETKTENPEEVLHQFPESKKISTYVFSLHAGPYQVWEDSYESIPLRLFVRKS
LAKYIDPKDWFLFTKDGFAFFNSYFGIPYPFQKYDQIIVPEFNFGAMENVAAVTFSERFVSRSPMTRNQRENLSDVILHE
MAHMWFGNLVTMKWWNGLWLNESFATYMASLAQAKNSEFQETWISFFEKMKQWAYEEDSFSTNHPVEAKVNDTEEAFTQF
DGITYGKGASVLKQLVFFIGEESFQKGVQNYLRKYSYSNSTLVDFLKELEFASGFSMKKWSKDWLETKGTNQIELTTICA
DNHLYGKIVQSAPGPENKLRDHKTVLGLYFFDRSNKQISYEEFPVVYSGRSSQAILQVKSCPDYVFINAEDHDFAIWSWT
SVNKDNLEFVLEFDNDPMRKLILWTDYFRQVSLANLSFDEFKETAIRLYPMETDTKIKRWLLSRLTSDTGSSYFTSRFWF
PESKRNNHLDSLQNFILSELTKAKAGSDEQKYLFLSLIDSSFTESSQKRLYEILENKLSFPGLKLDQDLRWNMIVKLSSL
AIDRNKIQTMIDREKKLDPSNRGVNSSLAAEAAEPNPKIKDKWIQILLNPKASDYSSSTLRVVSYSLFPEHQKGIQLQFL
DTYFAALDKFQHTDDENYLDAFAKSLAPDFCTDETLLILKKFTNNHPKLPASVKKTLWKQIDSEKRCIQIKNKHKDLILE
>Mature_880_residues
MKQTLAILIIGFLLIFQHCRLTKPNYHLTLQEAEYRYETIENIKYNLDIQLSTKDSFTGKVDIQFVGKRIRDLRLDYFQG
EIKSIVFNDEPLTQFEYKNGQVQLPSDRMMIGNNSLSIRFETPFAKTGNGLHKFLDPDDKETYIYSQFEAFHANKMFPCF
DQPDLKATFQLSVTAPKNWKVISTTLPTSETKTENPEEVLHQFPESKKISTYVFSLHAGPYQVWEDSYESIPLRLFVRKS
LAKYIDPKDWFLFTKDGFAFFNSYFGIPYPFQKYDQIIVPEFNFGAMENVAAVTFSERFVSRSPMTRNQRENLSDVILHE
MAHMWFGNLVTMKWWNGLWLNESFATYMASLAQAKNSEFQETWISFFEKMKQWAYEEDSFSTNHPVEAKVNDTEEAFTQF
DGITYGKGASVLKQLVFFIGEESFQKGVQNYLRKYSYSNSTLVDFLKELEFASGFSMKKWSKDWLETKGTNQIELTTICA
DNHLYGKIVQSAPGPENKLRDHKTVLGLYFFDRSNKQISYEEFPVVYSGRSSQAILQVKSCPDYVFINAEDHDFAIWSWT
SVNKDNLEFVLEFDNDPMRKLILWTDYFRQVSLANLSFDEFKETAIRLYPMETDTKIKRWLLSRLTSDTGSSYFTSRFWF
PESKRNNHLDSLQNFILSELTKAKAGSDEQKYLFLSLIDSSFTESSQKRLYEILENKLSFPGLKLDQDLRWNMIVKLSSL
AIDRNKIQTMIDREKKLDPSNRGVNSSLAAEAAEPNPKIKDKWIQILLNPKASDYSSSTLRVVSYSLFPEHQKGIQLQFL
DTYFAALDKFQHTDDENYLDAFAKSLAPDFCTDETLLILKKFTNNHPKLPASVKKTLWKQIDSEKRCIQIKNKHKDLILE

Specific function: Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=388, Percent_Identity=31.9587628865979, Blast_Score=194, Evalue=4e-49,
Organism=Homo sapiens, GI132814467, Length=336, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI157266300, Length=349, Percent_Identity=32.0916905444126, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI61742775, Length=507, Percent_Identity=28.0078895463511, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI61742777, Length=507, Percent_Identity=28.0078895463511, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI310123622, Length=359, Percent_Identity=32.033426183844, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI310133497, Length=359, Percent_Identity=31.4763231197772, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI194306629, Length=514, Percent_Identity=28.5992217898833, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI11641261, Length=514, Percent_Identity=28.5992217898833, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI94818891, Length=365, Percent_Identity=29.5890410958904, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI94818901, Length=365, Percent_Identity=29.5890410958904, Blast_Score=157, Evalue=5e-38,
Organism=Homo sapiens, GI7019561, Length=315, Percent_Identity=30.7936507936508, Blast_Score=150, Evalue=7e-36,
Organism=Homo sapiens, GI194239713, Length=335, Percent_Identity=30.4477611940298, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI4505029, Length=421, Percent_Identity=24.9406175771971, Blast_Score=113, Evalue=8e-25,
Organism=Homo sapiens, GI40316915, Length=341, Percent_Identity=23.4604105571848, Blast_Score=87, Evalue=7e-17,
Organism=Escherichia coli, GI1787163, Length=463, Percent_Identity=26.133909287257, Blast_Score=109, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71989076, Length=355, Percent_Identity=31.5492957746479, Blast_Score=193, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71989071, Length=355, Percent_Identity=31.5492957746479, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI115533278, Length=348, Percent_Identity=29.8850574712644, Blast_Score=177, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI115533276, Length=348, Percent_Identity=29.8850574712644, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71990873, Length=336, Percent_Identity=30.952380952381, Blast_Score=159, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI133903840, Length=373, Percent_Identity=30.2949061662198, Blast_Score=156, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17565628, Length=328, Percent_Identity=29.8780487804878, Blast_Score=152, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17569221, Length=358, Percent_Identity=29.8882681564246, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17569225, Length=363, Percent_Identity=28.3746556473829, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI193206926, Length=479, Percent_Identity=26.7223382045929, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193206928, Length=358, Percent_Identity=27.9329608938547, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71984353, Length=373, Percent_Identity=24.1286863270777, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71984339, Length=373, Percent_Identity=24.1286863270777, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17544504, Length=329, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71993840, Length=385, Percent_Identity=22.8571428571429, Blast_Score=89, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI9755335, Length=551, Percent_Identity=29.4010889292196, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6321837, Length=313, Percent_Identity=36.4217252396166, Blast_Score=188, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322054, Length=306, Percent_Identity=25.8169934640523, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6324283, Length=451, Percent_Identity=25.4988913525499, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24655252, Length=341, Percent_Identity=32.8445747800587, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24655274, Length=341, Percent_Identity=32.8445747800587, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24655260, Length=341, Percent_Identity=32.8445747800587, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24655265, Length=341, Percent_Identity=32.8445747800587, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24655268, Length=341, Percent_Identity=32.8445747800587, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24655257, Length=341, Percent_Identity=32.8445747800587, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24651025, Length=307, Percent_Identity=37.785016286645, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24651023, Length=307, Percent_Identity=37.785016286645, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24651021, Length=307, Percent_Identity=37.785016286645, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21358341, Length=325, Percent_Identity=36, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24646516, Length=400, Percent_Identity=31.25, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24646518, Length=400, Percent_Identity=31.25, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI45550850, Length=496, Percent_Identity=27.8225806451613, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24650973, Length=496, Percent_Identity=27.8225806451613, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24646514, Length=377, Percent_Identity=31.2997347480106, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24651016, Length=295, Percent_Identity=35.9322033898305, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24646512, Length=336, Percent_Identity=31.8452380952381, Blast_Score=166, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24646510, Length=336, Percent_Identity=31.8452380952381, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI161078673, Length=342, Percent_Identity=30.9941520467836, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571901, Length=342, Percent_Identity=30.9941520467836, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI221379089, Length=560, Percent_Identity=27.1428571428571, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24648786, Length=315, Percent_Identity=28.8888888888889, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24648790, Length=339, Percent_Identity=28.9085545722714, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI221330574, Length=477, Percent_Identity=26.4150943396226, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571792, Length=387, Percent_Identity=26.3565891472868, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24648784, Length=360, Percent_Identity=27.2222222222222, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281362221, Length=329, Percent_Identity=26.4437689969605, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281362224, Length=341, Percent_Identity=24.9266862170088, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221458256, Length=341, Percent_Identity=24.9266862170088, Blast_Score=116, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24584504, Length=445, Percent_Identity=24.4943820224719, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585062, Length=398, Percent_Identity=25.8793969849246, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585064, Length=398, Percent_Identity=25.8793969849246, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585066, Length=398, Percent_Identity=25.8793969849246, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45550350, Length=398, Percent_Identity=25.8793969849246, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641062, Length=363, Percent_Identity=22.5895316804408, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641060, Length=346, Percent_Identity=22.2543352601156, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012778
- InterPro:   IPR001930
- InterPro:   IPR014782 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 102665; Mature: 102665

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTLAILIIGFLLIFQHCRLTKPNYHLTLQEAEYRYETIENIKYNLDIQLSTKDSFTGK
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCEEEEEEEEECCCCCCCE
VDIQFVGKRIRDLRLDYFQGEIKSIVFNDEPLTQFEYKNGQVQLPSDRMMIGNNSLSIRF
EEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCEEECCCCCEEECCCEEEEEE
ETPFAKTGNGLHKFLDPDDKETYIYSQFEAFHANKMFPCFDQPDLKATFQLSVTAPKNWK
CCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCE
VISTTLPTSETKTENPEEVLHQFPESKKISTYVFSLHAGPYQVWEDSYESIPLRLFVRKS
EEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCHHHHHCCCCCCCHHHHHHHH
LAKYIDPKDWFLFTKDGFAFFNSYFGIPYPFQKYDQIIVPEFNFGAMENVAAVTFSERFV
HHHHCCCCCCEEEECCCHHHHHHCCCCCCCHHHCCEEEECCCCCCCHHHHHEEEHHHHHH
SRSPMTRNQRENLSDVILHEMAHMWFGNLVTMKWWNGLWLNESFATYMASLAQAKNSEFQ
CCCCCCCCHHCCHHHHHHHHHHHHHHCCEEEEEECCCEEECCHHHHHHHHHHHHCCCHHH
ETWISFFEKMKQWAYEEDSFSTNHPVEAKVNDTEEAFTQFDGITYGKGASVLKQLVFFIG
HHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHC
EESFQKGVQNYLRKYSYSNSTLVDFLKELEFASGFSMKKWSKDWLETKGTNQIELTTICA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEE
DNHLYGKIVQSAPGPENKLRDHKTVLGLYFFDRSNKQISYEEFPVVYSGRSSQAILQVKS
CCCHHHHHHHCCCCCHHHHHHHHEEEEEEEEECCCCEECCCCCCEEECCCCCCEEEEEEC
CPDYVFINAEDHDFAIWSWTSVNKDNLEFVLEFDNDPMRKLILWTDYFRQVSLANLSFDE
CCCEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHH
FKETAIRLYPMETDTKIKRWLLSRLTSDTGSSYFTSRFWFPESKRNNHLDSLQNFILSEL
HHCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
TKAKAGSDEQKYLFLSLIDSSFTESSQKRLYEILENKLSFPGLKLDQDLRWNMIVKLSSL
HHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHH
AIDRNKIQTMIDREKKLDPSNRGVNSSLAAEAAEPNPKIKDKWIQILLNPKASDYSSSTL
HHCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHEEEEEECCCCCCCCCCEE
RVVSYSLFPEHQKGIQLQFLDTYFAALDKFQHTDDENYLDAFAKSLAPDFCTDETLLILK
EEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
KFTNNHPKLPASVKKTLWKQIDSEKRCIQIKNKHKDLILE
HHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MKQTLAILIIGFLLIFQHCRLTKPNYHLTLQEAEYRYETIENIKYNLDIQLSTKDSFTGK
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCEEEEEEEEECCCCCCCE
VDIQFVGKRIRDLRLDYFQGEIKSIVFNDEPLTQFEYKNGQVQLPSDRMMIGNNSLSIRF
EEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCEEECCCCCEEECCCEEEEEE
ETPFAKTGNGLHKFLDPDDKETYIYSQFEAFHANKMFPCFDQPDLKATFQLSVTAPKNWK
CCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCE
VISTTLPTSETKTENPEEVLHQFPESKKISTYVFSLHAGPYQVWEDSYESIPLRLFVRKS
EEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCHHHHHCCCCCCCHHHHHHHH
LAKYIDPKDWFLFTKDGFAFFNSYFGIPYPFQKYDQIIVPEFNFGAMENVAAVTFSERFV
HHHHCCCCCCEEEECCCHHHHHHCCCCCCCHHHCCEEEECCCCCCCHHHHHEEEHHHHHH
SRSPMTRNQRENLSDVILHEMAHMWFGNLVTMKWWNGLWLNESFATYMASLAQAKNSEFQ
CCCCCCCCHHCCHHHHHHHHHHHHHHCCEEEEEECCCEEECCHHHHHHHHHHHHCCCHHH
ETWISFFEKMKQWAYEEDSFSTNHPVEAKVNDTEEAFTQFDGITYGKGASVLKQLVFFIG
HHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHC
EESFQKGVQNYLRKYSYSNSTLVDFLKELEFASGFSMKKWSKDWLETKGTNQIELTTICA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEE
DNHLYGKIVQSAPGPENKLRDHKTVLGLYFFDRSNKQISYEEFPVVYSGRSSQAILQVKS
CCCHHHHHHHCCCCCHHHHHHHHEEEEEEEEECCCCEECCCCCCEEECCCCCCEEEEEEC
CPDYVFINAEDHDFAIWSWTSVNKDNLEFVLEFDNDPMRKLILWTDYFRQVSLANLSFDE
CCCEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHH
FKETAIRLYPMETDTKIKRWLLSRLTSDTGSSYFTSRFWFPESKRNNHLDSLQNFILSEL
HHCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
TKAKAGSDEQKYLFLSLIDSSFTESSQKRLYEILENKLSFPGLKLDQDLRWNMIVKLSSL
HHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHH
AIDRNKIQTMIDREKKLDPSNRGVNSSLAAEAAEPNPKIKDKWIQILLNPKASDYSSSTL
HHCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHEEEEEECCCCCCCCCCEE
RVVSYSLFPEHQKGIQLQFLDTYFAALDKFQHTDDENYLDAFAKSLAPDFCTDETLLILK
EEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
KFTNNHPKLPASVKKTLWKQIDSEKRCIQIKNKHKDLILE
HHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7909302; 7765336 [H]