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The map label for this gene is 183222704

Identifier: 183222704

GI number: 183222704

Start: 3470861

End: 3471628

Strand: Direct

Name: 183222704

Synonym: LEPBI_I3360

Alternate gene names: NA

Gene position: 3470861-3471628 (Clockwise)

Preceding gene: 183222702

Following gene: 183222712

Centisome position: 96.42

GC content: 38.67

Gene sequence:

>768_bases
ATGGTGTTCGTCTCTTGTATCTCCATCATCAGTCCAGGTGAGGTGGGGCTTATGTGGAGACCTTATAGCACAGGTCTCAG
CCAAAAACCATTAGAATCTAGAGTGCAGACTTATATGCCATGGAACAGTGTTTATGTTTATTCTGTCCAATGGAGTAGTT
TCCAAGAGAAAGTGGAAGTGTTAACAAGAGATGATTTGACGATCACGGTGACTGCCGACATCATCATTCGACCGATCCAA
AATGAAATCTATGAACTGGAGATGGAAATCGGAAGGGATTACTATGAAAAAGTAGTCAAACCACAATTTCGAACCGCCAT
CCGAAATATTTTATCGGCGTATAACATGGTTTCGATATCCAAAGAAACTCCGAACGTTTCTGCCCAAATTAAAAAGTCAC
TCGCTGAAAAATTAAAATACAAACATATCGAAATTGATGATGTGATTGTGGATGATGTTGAATATAGTCCTTCAATCTTA
AAAGCCATTGAAAGTAAACTCACCAAACAACAAGAACAAGAACAAATGAAGTTTGAGATTAACATTGCGAAACGTGATGC
GGAAATTCAACAAATCTCAGCAGAAGCGAAAGCAAAGGCTGTATTGATTGAGGCGGAAGCACAAGCCAAAGCACAAAGGA
TGATATCTGAATCGTTAACGCCCAAATACATCCAACTCAAAGCAATGGAAAATCCGAATAACAAATTGATTTTTGTTCCC
AATGGAAAAGATGGATTGCCAATCATTGTGAATACAGACGGGAAATAA

Upstream 100 bases:

>100_bases
ATAAGAAAAGGAACATCTGTTTTAGTCTAATAGTTTAACTATGAAACGTCGATCCATTTTTCTCACAAGTTTACGGTTTG
CTCCTGTTTTGTTTCTTGGG

Downstream 100 bases:

>100_bases
GTGGGATCCTATCACCAATATAAATTGGTTTTTCAAAATGCAGTGCTGAACATTAGGCACTGCAGTTTAAAAGTTTACAA
ATTATTGGACTGGAGTTCCT

Product: putative signal peptide

Products: NA

Alternate protein names: Membrane Protease Subunit Stomatin/Prohibitin-Like Protein; Band 7 Family Protein; Protease; Membrane Protease; SPFH/Band 7 Family Protein; SPFH Domain-Containing Protein/Band 7 Family Protein; Spfh Domain Protein

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MVFVSCISIISPGEVGLMWRPYSTGLSQKPLESRVQTYMPWNSVYVYSVQWSSFQEKVEVLTRDDLTITVTADIIIRPIQ
NEIYELEMEIGRDYYEKVVKPQFRTAIRNILSAYNMVSISKETPNVSAQIKKSLAEKLKYKHIEIDDVIVDDVEYSPSIL
KAIESKLTKQQEQEQMKFEINIAKRDAEIQQISAEAKAKAVLIEAEAQAKAQRMISESLTPKYIQLKAMENPNNKLIFVP
NGKDGLPIIVNTDGK

Sequences:

>Translated_255_residues
MVFVSCISIISPGEVGLMWRPYSTGLSQKPLESRVQTYMPWNSVYVYSVQWSSFQEKVEVLTRDDLTITVTADIIIRPIQ
NEIYELEMEIGRDYYEKVVKPQFRTAIRNILSAYNMVSISKETPNVSAQIKKSLAEKLKYKHIEIDDVIVDDVEYSPSIL
KAIESKLTKQQEQEQMKFEINIAKRDAEIQQISAEAKAKAVLIEAEAQAKAQRMISESLTPKYIQLKAMENPNNKLIFVP
NGKDGLPIIVNTDGK
>Mature_255_residues
MVFVSCISIISPGEVGLMWRPYSTGLSQKPLESRVQTYMPWNSVYVYSVQWSSFQEKVEVLTRDDLTITVTADIIIRPIQ
NEIYELEMEIGRDYYEKVVKPQFRTAIRNILSAYNMVSISKETPNVSAQIKKSLAEKLKYKHIEIDDVIVDDVEYSPSIL
KAIESKLTKQQEQEQMKFEINIAKRDAEIQQISAEAKAKAVLIEAEAQAKAQRMISESLTPKYIQLKAMENPNNKLIFVP
NGKDGLPIIVNTDGK

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6005854, Length=175, Percent_Identity=23.4285714285714, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI221307584, Length=175, Percent_Identity=23.4285714285714, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321670, Length=209, Percent_Identity=20.0956937799043, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 29081; Mature: 29081

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFVSCISIISPGEVGLMWRPYSTGLSQKPLESRVQTYMPWNSVYVYSVQWSSFQEKVEV
CEEEEEEHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHH
LTRDDLTITVTADIIIRPIQNEIYELEMEIGRDYYEKVVKPQFRTAIRNILSAYNMVSIS
HCCCCEEEEEEEHEEEEHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHEEEEC
KETPNVSAQIKKSLAEKLKYKHIEIDDVIVDDVEYSPSILKAIESKLTKQQEQEQMKFEI
CCCCCHHHHHHHHHHHHHHHCCCEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEE
NIAKRDAEIQQISAEAKAKAVLIEAEAQAKAQRMISESLTPKYIQLKAMENPNNKLIFVP
EEECCCHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEE
NGKDGLPIIVNTDGK
CCCCCCEEEEECCCC
>Mature Secondary Structure
MVFVSCISIISPGEVGLMWRPYSTGLSQKPLESRVQTYMPWNSVYVYSVQWSSFQEKVEV
CEEEEEEHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHH
LTRDDLTITVTADIIIRPIQNEIYELEMEIGRDYYEKVVKPQFRTAIRNILSAYNMVSIS
HCCCCEEEEEEEHEEEEHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHEEEEC
KETPNVSAQIKKSLAEKLKYKHIEIDDVIVDDVEYSPSILKAIESKLTKQQEQEQMKFEI
CCCCCHHHHHHHHHHHHHHHCCCEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEE
NIAKRDAEIQQISAEAKAKAVLIEAEAQAKAQRMISESLTPKYIQLKAMENPNNKLIFVP
EEECCCHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEE
NGKDGLPIIVNTDGK
CCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA