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The map label for this gene is dapE [H]

Identifier: 183222702

GI number: 183222702

Start: 3468651

End: 3470093

Strand: Direct

Name: dapE [H]

Synonym: LEPBI_I3358

Alternate gene names: 183222702

Gene position: 3468651-3470093 (Clockwise)

Preceding gene: 183222701

Following gene: 183222704

Centisome position: 96.36

GC content: 39.78

Gene sequence:

>1443_bases
ATGAAGCGTATCATTTGGCTAGGACTCTTTTCTATTTTTTTATTACAATGTTCCTTTGGTCAAAAGGTACAGTATGCTGA
ATTAAAAAAAAACTATCCCAATGTGAATTGGGAAAATCGACGCAATGAAGCGGTTCGTTACTTAGCAGATATATTAAAAA
TTCCATCAGTACGTGGAAACGAAATCCAAGTCACGAAGTACATCCAATCAGTTCTTTCGAAGGAAGGAATTAGCTCACGA
TTAGTGTTTGATCCCAAATTTCCAAACCGTCCGAACTTAGTTGCGGAACTTCCTGCTACAGTACCCAATCCAGAACCCGG
GATCATACTGGCGAACCATTTAGACACAGTTGAATTTGATGCCAAAGAATGGAAAATGAATCCTCTCGCAGGAACAGTTC
GGGATGGCAGAGTATGGGGGCGCGGTGCAATAGATATGAAGGGCATGGCTGTTATGGAACTTGTTGCCTTTTTAGAACTC
AAACGTTCAGGAATTCCAAGGTCTCGTAAAATCATGTATTTAGCGTTAGCTGATGAAGAGTCTGGATCTGTTCTTGGCGG
AAAGTATATGACCTCACAGCAGAAAAAAATCTTTGAAGGGTATGAATATGCGATTAACGAAGGTGGAGTGGCAACGAGAG
ACATCGTCATCCCTGGATCTACGATCTTTAACATACAGTATGCGGAAAAAGGAAATATTTGGTTACGAGCAAAAATTACT
GGTACAAGTGGACATGGTTCTTCACCTCCGAACCAATACCCAGCATTAGCACTAATTCAGTTTTTTAATGAAGTACGAGA
GCTGGAATCAGACATTCGTATCACAGAAGAGACAGATGCATTTTTTTATCAATTGGGAACAATCAGTTCTTTTCCAAAAT
CTTTTTTCTTAAAAAATGCAAGAAATCCACTGATCAAACCACTTTTACATCCAACCATTAGAAGCAATCGCCACCTAACA
GCAATGACTACCAATACAAAATCCATCACGGGATTTCGAACAAGTGAAGGTGAGGGTGGTGAAAATGTGATTGCCGGTGA
AGCTAGCGGACGATTGGACATACGCACATTGCCTGGAGTCGATATAGAAGAGTTTGCCAAAAAAGTAAAAACCATTGCCA
CAAAATACAATGCAGAAATCACCTTTACCGACATCAATCCAACAGATGTAACGCCAATTCAAACCAGGTTTTTTAGCACA
CTCGCCGCTGTTTCCGTCAATAAGTTTCCAAACAGTACAGTGACCCCGTTTTTATCTCCTGGTAAAACAGACAATTCCTA
CTTACGTAAAATCGGAATCAAAGCATATGGGCTGATCCCTGCTGTTTTAAAAGCCGAAGACATTGATGGCATGCATGGTA
AAAATGAAAACATGACCATTGATAATTTGGAATTAGGAACTAAAATTCTTTTTGAAACGTTGGTAGAGATGAACCAATCA
TAA

Upstream 100 bases:

>100_bases
GCATTGTGAGGCTTGTGCTTCGAAAAATTTAAATCGAATTTGCTTTTAAGTTTTAAAATCCATGATTCTCTTTTTGTTCA
CAAGCACTGGGAGAAACAGG

Downstream 100 bases:

>100_bases
TAGCAGATTCTTTCAATCAAAGAACGTTATTTGATACTGAAATGGTTCGTTTTACAATCGTATTGAAACTGTTTTGTTGA
ATCATCCTGGGAGATACAAA

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MKRIIWLGLFSIFLLQCSFGQKVQYAELKKNYPNVNWENRRNEAVRYLADILKIPSVRGNEIQVTKYIQSVLSKEGISSR
LVFDPKFPNRPNLVAELPATVPNPEPGIILANHLDTVEFDAKEWKMNPLAGTVRDGRVWGRGAIDMKGMAVMELVAFLEL
KRSGIPRSRKIMYLALADEESGSVLGGKYMTSQQKKIFEGYEYAINEGGVATRDIVIPGSTIFNIQYAEKGNIWLRAKIT
GTSGHGSSPPNQYPALALIQFFNEVRELESDIRITEETDAFFYQLGTISSFPKSFFLKNARNPLIKPLLHPTIRSNRHLT
AMTTNTKSITGFRTSEGEGGENVIAGEASGRLDIRTLPGVDIEEFAKKVKTIATKYNAEITFTDINPTDVTPIQTRFFST
LAAVSVNKFPNSTVTPFLSPGKTDNSYLRKIGIKAYGLIPAVLKAEDIDGMHGKNENMTIDNLELGTKILFETLVEMNQS

Sequences:

>Translated_480_residues
MKRIIWLGLFSIFLLQCSFGQKVQYAELKKNYPNVNWENRRNEAVRYLADILKIPSVRGNEIQVTKYIQSVLSKEGISSR
LVFDPKFPNRPNLVAELPATVPNPEPGIILANHLDTVEFDAKEWKMNPLAGTVRDGRVWGRGAIDMKGMAVMELVAFLEL
KRSGIPRSRKIMYLALADEESGSVLGGKYMTSQQKKIFEGYEYAINEGGVATRDIVIPGSTIFNIQYAEKGNIWLRAKIT
GTSGHGSSPPNQYPALALIQFFNEVRELESDIRITEETDAFFYQLGTISSFPKSFFLKNARNPLIKPLLHPTIRSNRHLT
AMTTNTKSITGFRTSEGEGGENVIAGEASGRLDIRTLPGVDIEEFAKKVKTIATKYNAEITFTDINPTDVTPIQTRFFST
LAAVSVNKFPNSTVTPFLSPGKTDNSYLRKIGIKAYGLIPAVLKAEDIDGMHGKNENMTIDNLELGTKILFETLVEMNQS
>Mature_480_residues
MKRIIWLGLFSIFLLQCSFGQKVQYAELKKNYPNVNWENRRNEAVRYLADILKIPSVRGNEIQVTKYIQSVLSKEGISSR
LVFDPKFPNRPNLVAELPATVPNPEPGIILANHLDTVEFDAKEWKMNPLAGTVRDGRVWGRGAIDMKGMAVMELVAFLEL
KRSGIPRSRKIMYLALADEESGSVLGGKYMTSQQKKIFEGYEYAINEGGVATRDIVIPGSTIFNIQYAEKGNIWLRAKIT
GTSGHGSSPPNQYPALALIQFFNEVRELESDIRITEETDAFFYQLGTISSFPKSFFLKNARNPLIKPLLHPTIRSNRHLT
AMTTNTKSITGFRTSEGEGGENVIAGEASGRLDIRTLPGVDIEEFAKKVKTIATKYNAEITFTDINPTDVTPIQTRFFST
LAAVSVNKFPNSTVTPFLSPGKTDNSYLRKIGIKAYGLIPAVLKAEDIDGMHGKNENMTIDNLELGTKILFETLVEMNQS

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI269846968, Length=381, Percent_Identity=25.7217847769029, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1790395, Length=178, Percent_Identity=30.8988764044944, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322289, Length=496, Percent_Identity=21.7741935483871, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649208, Length=418, Percent_Identity=23.6842105263158, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24649202, Length=412, Percent_Identity=27.4271844660194, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24649204, Length=412, Percent_Identity=27.4271844660194, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24649210, Length=418, Percent_Identity=24.1626794258373, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24649212, Length=216, Percent_Identity=28.7037037037037, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356353, Length=412, Percent_Identity=26.2135922330097, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649206, Length=413, Percent_Identity=22.5181598062954, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 53542; Mature: 53542

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIIWLGLFSIFLLQCSFGQKVQYAELKKNYPNVNWENRRNEAVRYLADILKIPSVRGN
CCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
EIQVTKYIQSVLSKEGISSRLVFDPKFPNRPNLVAELPATVPNPEPGIILANHLDTVEFD
EEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEC
AKEWKMNPLAGTVRDGRVWGRGAIDMKGMAVMELVAFLELKRSGIPRSRKIMYLALADEE
HHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
SGSVLGGKYMTSQQKKIFEGYEYAINEGGVATRDIVIPGSTIFNIQYAEKGNIWLRAKIT
CCCEECCHHHHHHHHHHHCCHHHEECCCCCEEEEEEECCCEEEEEEEECCCCEEEEEEEE
GTSGHGSSPPNQYPALALIQFFNEVRELESDIRITEETDAFFYQLGTISSFPKSFFLKNA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCEEEEECCCHHHCCHHHHHHCC
RNPLIKPLLHPTIRSNRHLTAMTTNTKSITGFRTSEGEGGENVIAGEASGRLDIRTLPGV
CCHHHHHHHCHHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCC
DIEEFAKKVKTIATKYNAEITFTDINPTDVTPIQTRFFSTLAAVSVNKFPNSTVTPFLSP
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GKTDNSYLRKIGIKAYGLIPAVLKAEDIDGMHGKNENMTIDNLELGTKILFETLVEMNQS
CCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRIIWLGLFSIFLLQCSFGQKVQYAELKKNYPNVNWENRRNEAVRYLADILKIPSVRGN
CCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
EIQVTKYIQSVLSKEGISSRLVFDPKFPNRPNLVAELPATVPNPEPGIILANHLDTVEFD
EEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEC
AKEWKMNPLAGTVRDGRVWGRGAIDMKGMAVMELVAFLELKRSGIPRSRKIMYLALADEE
HHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
SGSVLGGKYMTSQQKKIFEGYEYAINEGGVATRDIVIPGSTIFNIQYAEKGNIWLRAKIT
CCCEECCHHHHHHHHHHHCCHHHEECCCCCEEEEEEECCCEEEEEEEECCCCEEEEEEEE
GTSGHGSSPPNQYPALALIQFFNEVRELESDIRITEETDAFFYQLGTISSFPKSFFLKNA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCEEEEECCCHHHCCHHHHHHCC
RNPLIKPLLHPTIRSNRHLTAMTTNTKSITGFRTSEGEGGENVIAGEASGRLDIRTLPGV
CCHHHHHHHCHHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCC
DIEEFAKKVKTIATKYNAEITFTDINPTDVTPIQTRFFSTLAAVSVNKFPNSTVTPFLSP
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GKTDNSYLRKIGIKAYGLIPAVLKAEDIDGMHGKNENMTIDNLELGTKILFETLVEMNQS
CCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA