| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is acr1 [H]
Identifier: 183222619
GI number: 183222619
Start: 3387189
End: 3387962
Strand: Direct
Name: acr1 [H]
Synonym: LEPBI_I3274
Alternate gene names: 183222619
Gene position: 3387189-3387962 (Clockwise)
Preceding gene: 183222616
Following gene: 183222620
Centisome position: 94.1
GC content: 39.02
Gene sequence:
>774_bases ATGGGGATTGGTGCCTTAACCGCAGAACGATTGGCAAAAGAAGGAAATGATATCATAGGTGTCGATATCAATGTATCCCT TTTAAAAGATATCCAATTGAAAGTGGAATCACTCGGCAGAAAATTTTATGGATATGCTTGTGATATGTCCAAAGAAGGAC AAATTGAAGCACTGATTCAAAAAATTAAAAAAAAACAACTCAACTTTCGAATACTCATCAATAATGCAGGCATCGCACCC AGCGGTCCTTATGAAGGTAAGGAGTTTTCTGTTTGGGAAAAAGCTCTTCAAATCAATGTCAACGGACCAATGAAGTTGGT TTATGAATCCTTGCCGATCTTAAGAGCGCAAAAAGAGGCTTGCATTATCAATTTGGCAAGTATTGCCGGAAAATTTGGAA CAGAAGGAACTGTTACTTATTCTGCCACCAAACATGCAATGGTTGGATTTTCTCAAGCCTTAAAGATGGAGTTATATGAG ACTCAAATCGGTGTTAGTTGGATTTGTCCTTCTATGGTAAAAACTAGAATGATTGATGGGGTAAAACCTTCCTTTTTTAC GCCTATCATCGAACCTGACCAAGTCGCTAAGGCAATTTGTAAGGCCATTCAAAAAAATCCTGGTGAGGTGCTTGTTCCAT CCTATCTCCGATCCACAATTGTCATCATGCCAGCTCTATTCCCCAAATTTTCCCTATGGCTTGCTGTGAAAACAAAAGCT TCAAAAGGTTGGTTACTCGCCAACAAGGGACTTGAGAAAAATATTCCTGTTTAG
Upstream 100 bases:
>100_bases AGTCTTTTTCCTAAATGATTCGGATTGACGAAACTAAAAAATAGATTAGATTCAATGTATGAAATTATCAGGAAACACGA TTTTAATTACAGGATGTGGA
Downstream 100 bases:
>100_bases AGGATAGGTTTTATGCACATTTCTGAGATCCTTGGTAAAAAACAGACGACGATCAGCTTCGAATTTTTCCCCCCTAAAAA TGAGGAAGCTTCCGAGGATT
Product: SDR family dehydrogenase/reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MGIGALTAERLAKEGNDIIGVDINVSLLKDIQLKVESLGRKFYGYACDMSKEGQIEALIQKIKKKQLNFRILINNAGIAP SGPYEGKEFSVWEKALQINVNGPMKLVYESLPILRAQKEACIINLASIAGKFGTEGTVTYSATKHAMVGFSQALKMELYE TQIGVSWICPSMVKTRMIDGVKPSFFTPIIEPDQVAKAICKAIQKNPGEVLVPSYLRSTIVIMPALFPKFSLWLAVKTKA SKGWLLANKGLEKNIPV
Sequences:
>Translated_257_residues MGIGALTAERLAKEGNDIIGVDINVSLLKDIQLKVESLGRKFYGYACDMSKEGQIEALIQKIKKKQLNFRILINNAGIAP SGPYEGKEFSVWEKALQINVNGPMKLVYESLPILRAQKEACIINLASIAGKFGTEGTVTYSATKHAMVGFSQALKMELYE TQIGVSWICPSMVKTRMIDGVKPSFFTPIIEPDQVAKAICKAIQKNPGEVLVPSYLRSTIVIMPALFPKFSLWLAVKTKA SKGWLLANKGLEKNIPV >Mature_256_residues GIGALTAERLAKEGNDIIGVDINVSLLKDIQLKVESLGRKFYGYACDMSKEGQIEALIQKIKKKQLNFRILINNAGIAPS GPYEGKEFSVWEKALQINVNGPMKLVYESLPILRAQKEACIINLASIAGKFGTEGTVTYSATKHAMVGFSQALKMELYET QIGVSWICPSMVKTRMIDGVKPSFFTPIIEPDQVAKAICKAIQKNPGEVLVPSYLRSTIVIMPALFPKFSLWLAVKTKAS KGWLLANKGLEKNIPV
Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI142976729, Length=232, Percent_Identity=29.3103448275862, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI210032110, Length=219, Percent_Identity=27.3972602739726, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI310128830, Length=254, Percent_Identity=26.3779527559055, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI310115468, Length=254, Percent_Identity=26.3779527559055, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI40807363, Length=222, Percent_Identity=27.027027027027, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI40254992, Length=204, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI157739938, Length=171, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI25282469, Length=197, Percent_Identity=25.3807106598985, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI109715829, Length=184, Percent_Identity=29.3478260869565, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503817, Length=223, Percent_Identity=31.8385650224215, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI210032112, Length=162, Percent_Identity=29.0123456790123, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI20149619, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=26.8817204301075, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=27.2189349112426, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI5031737, Length=175, Percent_Identity=27.4285714285714, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI32483357, Length=178, Percent_Identity=26.9662921348315, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI31543615, Length=209, Percent_Identity=21.5311004784689, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI87082100, Length=208, Percent_Identity=28.8461538461538, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787335, Length=176, Percent_Identity=26.7045454545455, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789057, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787820, Length=173, Percent_Identity=27.1676300578035, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI87082160, Length=179, Percent_Identity=29.608938547486, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786701, Length=181, Percent_Identity=27.6243093922652, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1788459, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508895, Length=219, Percent_Identity=28.7671232876712, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI193203115, Length=218, Percent_Identity=28.8990825688073, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI193203117, Length=218, Percent_Identity=28.8990825688073, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17564282, Length=261, Percent_Identity=27.9693486590038, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25147288, Length=190, Percent_Identity=25.7894736842105, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193203119, Length=126, Percent_Identity=30.952380952381, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17555706, Length=211, Percent_Identity=23.696682464455, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17561402, Length=181, Percent_Identity=29.2817679558011, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6323458, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=7e-15, Organism=Saccharomyces cerevisiae, GI6320089, Length=223, Percent_Identity=30.9417040358744, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=140, Percent_Identity=31.4285714285714, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI221510726, Length=214, Percent_Identity=30.8411214953271, Blast_Score=97, Evalue=8e-21, Organism=Drosophila melanogaster, GI281364892, Length=225, Percent_Identity=31.5555555555556, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI24581726, Length=236, Percent_Identity=30.5084745762712, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24640492, Length=222, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI21355319, Length=185, Percent_Identity=30.2702702702703, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24648944, Length=216, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=24, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24649181, Length=240, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24641232, Length=218, Percent_Identity=23.394495412844, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28571526, Length=212, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28235; Mature: 28104
Theoretical pI: Translated: 9.94; Mature: 9.94
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGIGALTAERLAKEGNDIIGVDINVSLLKDIQLKVESLGRKFYGYACDMSKEGQIEALIQ CCCCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCHHHEEEEECCCCCCCHHHHHH KIKKKQLNFRILINNAGIAPSGPYEGKEFSVWEKALQINVNGPMKLVYESLPILRAQKEA HHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHEEEEEECCCCHHHHHHHCCHHHCCCHH CIINLASIAGKFGTEGTVTYSATKHAMVGFSQALKMELYETQIGVSWICPSMVKTRMIDG HEEEHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHCC VKPSFFTPIIEPDQVAKAICKAIQKNPGEVLVPSYLRSTIVIMPALFPKFSLWLAVKTKA CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHCCCEEEEEEEEECC SKGWLLANKGLEKNIPV CCCEEEECCCCCCCCCC >Mature Secondary Structure GIGALTAERLAKEGNDIIGVDINVSLLKDIQLKVESLGRKFYGYACDMSKEGQIEALIQ CCCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCHHHEEEEECCCCCCCHHHHHH KIKKKQLNFRILINNAGIAPSGPYEGKEFSVWEKALQINVNGPMKLVYESLPILRAQKEA HHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHEEEEEECCCCHHHHHHHCCHHHCCCHH CIINLASIAGKFGTEGTVTYSATKHAMVGFSQALKMELYETQIGVSWICPSMVKTRMIDG HEEEHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHCC VKPSFFTPIIEPDQVAKAICKAIQKNPGEVLVPSYLRSTIVIMPALFPKFSLWLAVKTKA CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHCCCEEEEEEEEECC SKGWLLANKGLEKNIPV CCCEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA