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The map label for this gene is rfbB [C]

Identifier: 183222577

GI number: 183222577

Start: 3345090

End: 3346022

Strand: Direct

Name: rfbB [C]

Synonym: LEPBI_I3232

Alternate gene names: 183222577

Gene position: 3345090-3346022 (Clockwise)

Preceding gene: 183222576

Following gene: 183222578

Centisome position: 92.93

GC content: 39.66

Gene sequence:

>933_bases
ATGGCAAAAAGAATTCTCATTACCGGGGGAGCTGGGTTCATCGGTTCTCATCTAGCGGAAAACTTGCTCAATGCTGGAAA
CCAAATCATTGTTTTGGACAATTTTCACACAGGAAGGAAGGAAAATCTCACTCACCTCCTTTCCCATCCCAATTTTGAAC
TCATCCGTCATGACATCACCGATTCGATCAAACTAGAAGTGGATCAAATTTATAACATGGCTTGCCCTGCATCGCCAGTT
CATTACCAAAGTAACCCAATCAAAACCATCAAAACCAATGTATTAGGAACGATGAATATGTTGGGACTTGCCAAACGAGT
GAAAGCAAGAATCTTACAAGCTAGCACTTCCGAAGTATACGGAAATCCTTTGGAACACCCACAAAACGAATCGTATTGGG
GAAATGTAAACACCATCGGAATTCGTAGTTGTTATGACGAAGGGAAACGTGTCGCAGAAACTTTGTGTTTTGACTACCAT
AGACAACATGGAGTCGACATTCGAGTGATCCGAATTTTTAACACGTATGGTCCAAGGATGATTCCAGATGATGGCCGAGT
CGTGAGTAATTTTATCGTACAAGCATTACGCGGTGAGGACATCACCATTTATGGAGACGGAAGCCAAACAAGATCTTTTT
GTTATGTTGATGACCTTGTCAAAGGTATCATCAATATGATGAACGTAGAAAATTTCGTTGGCCCGGTGAATTTAGGAAAT
GATGGTGAGTTTACTGTAAAGGAACTTGCAGAACTTATTATTAAAGAAACAGGAAGTAAATCTAAGATCATTTACCTTCC
ACTTCCTCAAGATGATCCTGCTCGTCGAAAACCAAATTTGAGTTTGGCGAAAGAAAAATTGAATTATTCTACAACCGTTC
CACTTTTGGAAGGCGTAAAAAAAACCATCGAATATTTTAGCAAAAGAGTATAA

Upstream 100 bases:

>100_bases
GAATTTTTTCCTTGATCCACCTTCCAAAGACAACTAGGGTAAGTGCTTCTCGCAAATTTTCATTTGCGTAGGACACCGAC
TCCACAAATATAGAATCTCA

Downstream 100 bases:

>100_bases
AATGAAAATAGGCGTAATCAAAGAACCATCGTATGAAAACCGAGTTGCGATCACACCAGATGTGATTGATCCGTTGAAAA
AATTAGGATTCACAATTGCT

Product: putative dTDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MAKRILITGGAGFIGSHLAENLLNAGNQIIVLDNFHTGRKENLTHLLSHPNFELIRHDITDSIKLEVDQIYNMACPASPV
HYQSNPIKTIKTNVLGTMNMLGLAKRVKARILQASTSEVYGNPLEHPQNESYWGNVNTIGIRSCYDEGKRVAETLCFDYH
RQHGVDIRVIRIFNTYGPRMIPDDGRVVSNFIVQALRGEDITIYGDGSQTRSFCYVDDLVKGIINMMNVENFVGPVNLGN
DGEFTVKELAELIIKETGSKSKIIYLPLPQDDPARRKPNLSLAKEKLNYSTTVPLLEGVKKTIEYFSKRV

Sequences:

>Translated_310_residues
MAKRILITGGAGFIGSHLAENLLNAGNQIIVLDNFHTGRKENLTHLLSHPNFELIRHDITDSIKLEVDQIYNMACPASPV
HYQSNPIKTIKTNVLGTMNMLGLAKRVKARILQASTSEVYGNPLEHPQNESYWGNVNTIGIRSCYDEGKRVAETLCFDYH
RQHGVDIRVIRIFNTYGPRMIPDDGRVVSNFIVQALRGEDITIYGDGSQTRSFCYVDDLVKGIINMMNVENFVGPVNLGN
DGEFTVKELAELIIKETGSKSKIIYLPLPQDDPARRKPNLSLAKEKLNYSTTVPLLEGVKKTIEYFSKRV
>Mature_309_residues
AKRILITGGAGFIGSHLAENLLNAGNQIIVLDNFHTGRKENLTHLLSHPNFELIRHDITDSIKLEVDQIYNMACPASPVH
YQSNPIKTIKTNVLGTMNMLGLAKRVKARILQASTSEVYGNPLEHPQNESYWGNVNTIGIRSCYDEGKRVAETLCFDYHR
QHGVDIRVIRIFNTYGPRMIPDDGRVVSNFIVQALRGEDITIYGDGSQTRSFCYVDDLVKGIINMMNVENFVGPVNLGND
GEFTVKELAELIIKETGSKSKIIYLPLPQDDPARRKPNLSLAKEKLNYSTTVPLLEGVKKTIEYFSKRV

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=60.3896103896104, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI7657641, Length=323, Percent_Identity=31.2693498452012, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI56237023, Length=335, Percent_Identity=25.9701492537313, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI56118217, Length=335, Percent_Identity=25.9701492537313, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI189083684, Length=335, Percent_Identity=25.9701492537313, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788589, Length=343, Percent_Identity=24.198250728863, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI48994969, Length=272, Percent_Identity=25.3676470588235, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788365, Length=322, Percent_Identity=23.9130434782609, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=24.7787610619469, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788366, Length=287, Percent_Identity=27.5261324041812, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=309, Percent_Identity=57.2815533980583, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17568069, Length=332, Percent_Identity=28.3132530120482, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=332, Percent_Identity=26.5060240963855, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71982038, Length=334, Percent_Identity=26.6467065868263, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=329, Percent_Identity=25.2279635258359, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=23.1884057971014, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356223, Length=304, Percent_Identity=59.8684210526316, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI19923002, Length=319, Percent_Identity=24.1379310344828, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34775; Mature: 34644

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRILITGGAGFIGSHLAENLLNAGNQIIVLDNFHTGRKENLTHLLSHPNFELIRHDIT
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCC
DSIKLEVDQIYNMACPASPVHYQSNPIKTIKTNVLGTMNMLGLAKRVKARILQASTSEVY
CCCEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GNPLEHPQNESYWGNVNTIGIRSCYDEGKRVAETLCFDYHRQHGVDIRVIRIFNTYGPRM
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEE
IPDDGRVVSNFIVQALRGEDITIYGDGSQTRSFCYVDDLVKGIINMMNVENFVGPVNLGN
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC
DGEFTVKELAELIIKETGSKSKIIYLPLPQDDPARRKPNLSLAKEKLNYSTTVPLLEGVK
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
KTIEYFSKRV
HHHHHHHHCC
>Mature Secondary Structure 
AKRILITGGAGFIGSHLAENLLNAGNQIIVLDNFHTGRKENLTHLLSHPNFELIRHDIT
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCC
DSIKLEVDQIYNMACPASPVHYQSNPIKTIKTNVLGTMNMLGLAKRVKARILQASTSEVY
CCCEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GNPLEHPQNESYWGNVNTIGIRSCYDEGKRVAETLCFDYHRQHGVDIRVIRIFNTYGPRM
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEE
IPDDGRVVSNFIVQALRGEDITIYGDGSQTRSFCYVDDLVKGIINMMNVENFVGPVNLGN
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC
DGEFTVKELAELIIKETGSKSKIIYLPLPQDDPARRKPNLSLAKEKLNYSTTVPLLEGVK
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
KTIEYFSKRV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]