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The map label for this gene is oxyR [H]

Identifier: 183222357

GI number: 183222357

Start: 3123807

End: 3124724

Strand: Reverse

Name: oxyR [H]

Synonym: LEPBI_I3010

Alternate gene names: 183222357

Gene position: 3124724-3123807 (Counterclockwise)

Preceding gene: 183222369

Following gene: 183222356

Centisome position: 86.81

GC content: 35.51

Gene sequence:

>918_bases
ATGACAATTACTCAACTTCGATATATTGTTGCTTTGGATCAGTTTAAAAGTTTTGCTAAAGCCGCCGAACACTGCTTAGT
TGCTCAGCCAACATTAAGTCTACAAATTCAAAAAGTAGAACAAGAACTTGGATTTGATTTATTTGATCGAAGAAAAAATC
CGATCATCACGACAAAACTCGGTAAAGAAGTTGTCGAACAAGCAAAATCAACACTTAAAGAAGCGGACAAATTATTTGAA
ATCGCCGGCCAATGGAAAGATGAACCTGCTGGCAATATTTCATTAGGAATCATCCCTACTGTCAGCAATTATTTGATTCC
ATCAATCTATAAAAAATTGCAATCGGAATTTCCAAAAGTGAACTTTCGTATTTCAGAACTTCCTACTTTAACAATCATTG
AAAAATTAGAATCGGAGGAAATTGATTTGGGAATTCTTGCAACTCCTCTCAAAATATCAAATGTCGTCGAACTCCCACTC
TATTATGAACCATTTGTTGTCTACTATCCAAAGGATGCGAAAGAAAAATCTACCTCTGTCTCGATGAAACATATTGAGAA
GTATCCCTTACTTGTTTTGGGCGAAGAACATTGTTTTCGGCACCAATCATTAAAAATATGCAATCGAAATGCTTTGGCAA
AAATAGAAAGTGGGAGCGTGGAAACCTTAAAACGTATGGTGGATATGGGAATTGGGGTCACATTACTTCCCAAACTGGCA
GTGGATAAAGTTTCCGAACGGATTGTACCATTCCAATCACCGGAACCTGCACGTGAAATTAGTATGGTTTACAAAAAAGG
ATTTTATAAAACAAAAATCTTAAATAAACTTTCCAATTTAATACTCAATGTGATTCCAAAGGAATACCATAAAAAGGAAA
AATTCAAAGTGATCGGAGTTTCCATCGGACAGGATTAA

Upstream 100 bases:

>100_bases
GAATTCTCATCGCTATCCGCTAATGATAGTGAAGTCGGAAGGGATTGCAAGTTGAATTTAGATTCGAGTTGCCTAAGGAT
CGGTTTTTTAAGGAAATTTT

Downstream 100 bases:

>100_bases
TGACATAAGATGTAGTCATAGCTTTTATAAATCATATCATTTATAACATTTATTTTACAAATGACGCGATATGGGTTATA
TTCTTCTTAACAAGAAAAGG

Product: LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTITQLRYIVALDQFKSFAKAAEHCLVAQPTLSLQIQKVEQELGFDLFDRRKNPIITTKLGKEVVEQAKSTLKEADKLFE
IAGQWKDEPAGNISLGIIPTVSNYLIPSIYKKLQSEFPKVNFRISELPTLTIIEKLESEEIDLGILATPLKISNVVELPL
YYEPFVVYYPKDAKEKSTSVSMKHIEKYPLLVLGEEHCFRHQSLKICNRNALAKIESGSVETLKRMVDMGIGVTLLPKLA
VDKVSERIVPFQSPEPAREISMVYKKGFYKTKILNKLSNLILNVIPKEYHKKEKFKVIGVSIGQD

Sequences:

>Translated_305_residues
MTITQLRYIVALDQFKSFAKAAEHCLVAQPTLSLQIQKVEQELGFDLFDRRKNPIITTKLGKEVVEQAKSTLKEADKLFE
IAGQWKDEPAGNISLGIIPTVSNYLIPSIYKKLQSEFPKVNFRISELPTLTIIEKLESEEIDLGILATPLKISNVVELPL
YYEPFVVYYPKDAKEKSTSVSMKHIEKYPLLVLGEEHCFRHQSLKICNRNALAKIESGSVETLKRMVDMGIGVTLLPKLA
VDKVSERIVPFQSPEPAREISMVYKKGFYKTKILNKLSNLILNVIPKEYHKKEKFKVIGVSIGQD
>Mature_304_residues
TITQLRYIVALDQFKSFAKAAEHCLVAQPTLSLQIQKVEQELGFDLFDRRKNPIITTKLGKEVVEQAKSTLKEADKLFEI
AGQWKDEPAGNISLGIIPTVSNYLIPSIYKKLQSEFPKVNFRISELPTLTIIEKLESEEIDLGILATPLKISNVVELPLY
YEPFVVYYPKDAKEKSTSVSMKHIEKYPLLVLGEEHCFRHQSLKICNRNALAKIESGSVETLKRMVDMGIGVTLLPKLAV
DKVSERIVPFQSPEPAREISMVYKKGFYKTKILNKLSNLILNVIPKEYHKKEKFKVIGVSIGQD

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=275, Percent_Identity=36.3636363636364, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1787530, Length=255, Percent_Identity=24.7058823529412, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=24.3986254295533, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788748, Length=271, Percent_Identity=24.3542435424354, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=26.2798634812287, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787879, Length=303, Percent_Identity=24.7524752475248, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788887, Length=279, Percent_Identity=25.4480286738351, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=244, Percent_Identity=26.2295081967213, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=24.390243902439, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082132, Length=234, Percent_Identity=26.0683760683761, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=29.3706293706294, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=282, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787806, Length=171, Percent_Identity=23.3918128654971, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788296, Length=245, Percent_Identity=23.6734693877551, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=19.6551724137931, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34623; Mature: 34492

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITQLRYIVALDQFKSFAKAAEHCLVAQPTLSLQIQKVEQELGFDLFDRRKNPIITTKL
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCHHHCCCCCEEEHHH
GKEVVEQAKSTLKEADKLFEIAGQWKDEPAGNISLGIIPTVSNYLIPSIYKKLQSEFPKV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
NFRISELPTLTIIEKLESEEIDLGILATPLKISNVVELPLYYEPFVVYYPKDAKEKSTSV
EEEHHCCCHHHHHHHHCCCCCCEEEEECCEECCCEEECCEEECCEEEECCCCCCHHHHHH
SMKHIEKYPLLVLGEEHCFRHQSLKICNRNALAKIESGSVETLKRMVDMGIGVTLLPKLA
HHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHH
VDKVSERIVPFQSPEPAREISMVYKKGFYKTKILNKLSNLILNVIPKEYHKKEKFKVIGV
HHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEE
SIGQD
ECCCC
>Mature Secondary Structure 
TITQLRYIVALDQFKSFAKAAEHCLVAQPTLSLQIQKVEQELGFDLFDRRKNPIITTKL
CHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCHHHCCCCCEEEHHH
GKEVVEQAKSTLKEADKLFEIAGQWKDEPAGNISLGIIPTVSNYLIPSIYKKLQSEFPKV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
NFRISELPTLTIIEKLESEEIDLGILATPLKISNVVELPLYYEPFVVYYPKDAKEKSTSV
EEEHHCCCHHHHHHHHCCCCCCEEEEECCEECCCEEECCEEECCEEEECCCCCCHHHHHH
SMKHIEKYPLLVLGEEHCFRHQSLKICNRNALAKIESGSVETLKRMVDMGIGVTLLPKLA
HHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHH
VDKVSERIVPFQSPEPAREISMVYKKGFYKTKILNKLSNLILNVIPKEYHKKEKFKVIGV
HHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEE
SIGQD
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA