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The map label for this gene is flhA [H]

Identifier: 183221907

GI number: 183221907

Start: 2635274

End: 2637388

Strand: Reverse

Name: flhA [H]

Synonym: LEPBI_I2546

Alternate gene names: 183221907

Gene position: 2637388-2635274 (Counterclockwise)

Preceding gene: 183221908

Following gene: 183221906

Centisome position: 73.27

GC content: 43.45

Gene sequence:

>2115_bases
ATGAACTTTAAAGATATCCTGAAACAATCTGATGTCATTTTAGGTGTAGGAACATTGATGATCCTAGGGATGCTCATAGT
CCCTTTACCTGGTTTTGTTTTGGACATTCTCATTGTGGTGAGCATTGGGCTTGGACTTCTCATCCTCATGACCGCTTTGT
CTGTGACGGAACCCAGTGAATTTTCGATTTTTCCAAGTTTACTCCTGATCACGACCCTCTTTCGTCTGGCACTGAACGTA
TCCACCACTCGGCAGATTCTTTCCAAAGGCCCTGCGATGAATTCCAGTGTGATCGAAGCCTTTGGAACATTTGTTGTGGG
TGGGGAATCGGGACTTGGAAAGTATGTAGTGGGTCTTATTATCTTTATCATCCTCACCATTGTACAGGTGTTAGTCATCA
CAAAAGGTGCGACAAGGATCTCGGAAGTGGCTGCAAGGTTTACACTCGATGGATTGCCACAAAAACAAATGTCCATTGAT
ATGGAACTGAATAGTGGGGCGATCACGGAAGCAGAAGCCAAGGTGAAACGTAAAAAAGTCCAACGCGAAGTAGATTTTTA
TGGGGCCATGGATGGAGCATCCAAATTTGTGCAAGGGGATGTTAGGGCTGGTCTTATCATCACGGCCATCAATTTACTCG
GTGGGATTCTCATTGGTTCTACGATTCGCGGGGAATCGTTTTTAGCATCAATTGAAACCTACGGAAAGTTTACGATTGGA
GATGGTCTTGTTTCCCAAATTCCAGGACTCCTCTCTACAACTGCTACAGGTATCATTGTCACTCGTTCTAGTTCTGAAAA
AAAACTCACTGTCGAGATCAAAGACCAACTCTTTGGGAATGCCAAAACATTGTATGTGGTGGCGGGTGCACTTGGGTTAG
CAAGTTTCATTCCGGGGCTCCCTTTTTTCTCCCTTCTCTTTTTGGCAGGTGCCATTGGATACTTAGGGTATTCCATCGAA
CAAGTGGCCAAAGAAGAGATCAAAAAAATCGAAACCGTTTCCCAAGAAAAGACCCAAGAAAAAAAGCCAGAAAATTATAT
CAAAGAAATTTCAGTGGAAGCAATCCAGGTGGAACTTGGTCGCGATTTACTACCGTTAGTGGACGCCTCTTCTGGTGGGC
ACTTACTCGAACAAATTGCGAATACGCGGAAAAAATTTGCGATTGATTTTGGCCTTGTGATCCCTGCGATACGGATCATT
GACAATTTAGAAATCCCTCATGACAATTATAGCATTCGGATCAATGGGGTGGTAGTGGGGCAATCTGCAGTGCGAGCTGA
CAGGCTTATGGCCATGAACAATACTACGCGTAATTTGGAAGCTATTATTGGGGAACCTTTCACCGAACCAGCGTTTGGTT
TAAAGGCGACTTGGATTGACCCGAATGATAAAATCGAAGTGGAAAACAAAGGGTATTCGGTTGTAGATCCATCGACAGTC
ATCATCACTCATCTCAAAGAACTCATTTCCAATTATGCATCGCAACTTCTCGGAAGAGAAGAAGTGAAAGCTCTCCTCGA
ACATCTCCGCCAAACCCACCCAACCCTTGTCGGGGAATTGGATTATGACAAACAAGGAAGGCTCGGGATCATCCAACAAA
CATTACAGAATCTTTTGGCAGAAGGTTTGTCCATTAAGAACCTTCCGAAAATCATGGATGCAATTGCGAACCATCTCCCT
CGTACGAACAATCCATTTGATTTAGCGGAACATGTTAGACAAGCCTTATCACGACAAATCATCAATGATTTCCTCTCTCC
CGATGGAAAACTCCATGTGGTAACCATTGATCCGAGGATCATTGATCGTATGAACAAAAGTATCACACTTGATGAAACTG
ATGGAAGTAAACTCATCATCCTTCCTCATGATGTTCGAGTGAGAATATTAGAATCGGTTTACAATGAACTACAAAAGGCA
TTGGATGAAAACAGATTCCTGATCTTTGTAGTCTCTAGGTACTTAAGACAAGCCTTTGCATTCTTTTTGACAAAGGAACT
ACCCCCAAGGAACTTTGCAGTAATTGCTTCTGAAGAAATCCATCGAGGGGTTCCGACAGAAATTGCCTCGGTATTAAGCC
TTCCATCGCGAGAGGAACACCCACAAGAAGCTTAA

Upstream 100 bases:

>100_bases
GAAGTGGGAGATGAAATCCCACAAGAGTTCTTCCAAGCTGTGGTGCAGATCCTCATCACTCTGGAAAAGTTCAAAAAAAA
AGTAGGAATGGCATAACCAT

Downstream 100 bases:

>100_bases
GGAGATCCCTTTGACAGACCCAGTCCCATCGCACCGCATTTCTGTTGCTCCGATGATGGACTGGACCGACAGGCATTTTC
GTTATTTTATCCGACTTATC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MNFKDILKQSDVILGVGTLMILGMLIVPLPGFVLDILIVVSIGLGLLILMTALSVTEPSEFSIFPSLLLITTLFRLALNV
STTRQILSKGPAMNSSVIEAFGTFVVGGESGLGKYVVGLIIFIILTIVQVLVITKGATRISEVAARFTLDGLPQKQMSID
MELNSGAITEAEAKVKRKKVQREVDFYGAMDGASKFVQGDVRAGLIITAINLLGGILIGSTIRGESFLASIETYGKFTIG
DGLVSQIPGLLSTTATGIIVTRSSSEKKLTVEIKDQLFGNAKTLYVVAGALGLASFIPGLPFFSLLFLAGAIGYLGYSIE
QVAKEEIKKIETVSQEKTQEKKPENYIKEISVEAIQVELGRDLLPLVDASSGGHLLEQIANTRKKFAIDFGLVIPAIRII
DNLEIPHDNYSIRINGVVVGQSAVRADRLMAMNNTTRNLEAIIGEPFTEPAFGLKATWIDPNDKIEVENKGYSVVDPSTV
IITHLKELISNYASQLLGREEVKALLEHLRQTHPTLVGELDYDKQGRLGIIQQTLQNLLAEGLSIKNLPKIMDAIANHLP
RTNNPFDLAEHVRQALSRQIINDFLSPDGKLHVVTIDPRIIDRMNKSITLDETDGSKLIILPHDVRVRILESVYNELQKA
LDENRFLIFVVSRYLRQAFAFFLTKELPPRNFAVIASEEIHRGVPTEIASVLSLPSREEHPQEA

Sequences:

>Translated_704_residues
MNFKDILKQSDVILGVGTLMILGMLIVPLPGFVLDILIVVSIGLGLLILMTALSVTEPSEFSIFPSLLLITTLFRLALNV
STTRQILSKGPAMNSSVIEAFGTFVVGGESGLGKYVVGLIIFIILTIVQVLVITKGATRISEVAARFTLDGLPQKQMSID
MELNSGAITEAEAKVKRKKVQREVDFYGAMDGASKFVQGDVRAGLIITAINLLGGILIGSTIRGESFLASIETYGKFTIG
DGLVSQIPGLLSTTATGIIVTRSSSEKKLTVEIKDQLFGNAKTLYVVAGALGLASFIPGLPFFSLLFLAGAIGYLGYSIE
QVAKEEIKKIETVSQEKTQEKKPENYIKEISVEAIQVELGRDLLPLVDASSGGHLLEQIANTRKKFAIDFGLVIPAIRII
DNLEIPHDNYSIRINGVVVGQSAVRADRLMAMNNTTRNLEAIIGEPFTEPAFGLKATWIDPNDKIEVENKGYSVVDPSTV
IITHLKELISNYASQLLGREEVKALLEHLRQTHPTLVGELDYDKQGRLGIIQQTLQNLLAEGLSIKNLPKIMDAIANHLP
RTNNPFDLAEHVRQALSRQIINDFLSPDGKLHVVTIDPRIIDRMNKSITLDETDGSKLIILPHDVRVRILESVYNELQKA
LDENRFLIFVVSRYLRQAFAFFLTKELPPRNFAVIASEEIHRGVPTEIASVLSLPSREEHPQEA
>Mature_704_residues
MNFKDILKQSDVILGVGTLMILGMLIVPLPGFVLDILIVVSIGLGLLILMTALSVTEPSEFSIFPSLLLITTLFRLALNV
STTRQILSKGPAMNSSVIEAFGTFVVGGESGLGKYVVGLIIFIILTIVQVLVITKGATRISEVAARFTLDGLPQKQMSID
MELNSGAITEAEAKVKRKKVQREVDFYGAMDGASKFVQGDVRAGLIITAINLLGGILIGSTIRGESFLASIETYGKFTIG
DGLVSQIPGLLSTTATGIIVTRSSSEKKLTVEIKDQLFGNAKTLYVVAGALGLASFIPGLPFFSLLFLAGAIGYLGYSIE
QVAKEEIKKIETVSQEKTQEKKPENYIKEISVEAIQVELGRDLLPLVDASSGGHLLEQIANTRKKFAIDFGLVIPAIRII
DNLEIPHDNYSIRINGVVVGQSAVRADRLMAMNNTTRNLEAIIGEPFTEPAFGLKATWIDPNDKIEVENKGYSVVDPSTV
IITHLKELISNYASQLLGREEVKALLEHLRQTHPTLVGELDYDKQGRLGIIQQTLQNLLAEGLSIKNLPKIMDAIANHLP
RTNNPFDLAEHVRQALSRQIINDFLSPDGKLHVVTIDPRIIDRMNKSITLDETDGSKLIILPHDVRVRILESVYNELQKA
LDENRFLIFVVSRYLRQAFAFFLTKELPPRNFAVIASEEIHRGVPTEIASVLSLPSREEHPQEA

Specific function: Involved in the export of flagellum proteins [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=661, Percent_Identity=38.5779122541604, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 77159; Mature: 77159

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKDILKQSDVILGVGTLMILGMLIVPLPGFVLDILIVVSIGLGLLILMTALSVTEPSE
CCHHHHHHHCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FSIFPSLLLITTLFRLALNVSTTRQILSKGPAMNSSVIEAFGTFVVGGESGLGKYVVGLI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHCEEECCCCCHHHHHHHHH
IFIILTIVQVLVITKGATRISEVAARFTLDGLPQKQMSIDMELNSGAITEAEAKVKRKKV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
QREVDFYGAMDGASKFVQGDVRAGLIITAINLLGGILIGSTIRGESFLASIETYGKFTIG
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEC
DGLVSQIPGLLSTTATGIIVTRSSSEKKLTVEIKDQLFGNAKTLYVVAGALGLASFIPGL
CCHHHHCCHHHHHCCCEEEEECCCCCCEEEEEEHHHHCCCCCEEEHHHHHHHHHHHHCCC
PFFSLLFLAGAIGYLGYSIEQVAKEEIKKIETVSQEKTQEKKPENYIKEISVEAIQVELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
RDLLPLVDASSGGHLLEQIANTRKKFAIDFGLVIPAIRIIDNLEIPHDNYSIRINGVVVG
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC
QSAVRADRLMAMNNTTRNLEAIIGEPFTEPAFGLKATWIDPNDKIEVENKGYSVVDPSTV
CHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCEEECCCCCEEECCHHH
IITHLKELISNYASQLLGREEVKALLEHLRQTHPTLVGELDYDKQGRLGIIQQTLQNLLA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHH
EGLSIKNLPKIMDAIANHLPRTNNPFDLAEHVRQALSRQIINDFLSPDGKLHVVTIDPRI
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHH
IDRMNKSITLDETDGSKLIILPHDVRVRILESVYNELQKALDENRFLIFVVSRYLRQAFA
HHHCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
FFLTKELPPRNFAVIASEEIHRGVPTEIASVLSLPSREEHPQEA
HHHHHCCCCCCEEEEECHHHHCCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNFKDILKQSDVILGVGTLMILGMLIVPLPGFVLDILIVVSIGLGLLILMTALSVTEPSE
CCHHHHHHHCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FSIFPSLLLITTLFRLALNVSTTRQILSKGPAMNSSVIEAFGTFVVGGESGLGKYVVGLI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHCEEECCCCCHHHHHHHHH
IFIILTIVQVLVITKGATRISEVAARFTLDGLPQKQMSIDMELNSGAITEAEAKVKRKKV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
QREVDFYGAMDGASKFVQGDVRAGLIITAINLLGGILIGSTIRGESFLASIETYGKFTIG
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEC
DGLVSQIPGLLSTTATGIIVTRSSSEKKLTVEIKDQLFGNAKTLYVVAGALGLASFIPGL
CCHHHHCCHHHHHCCCEEEEECCCCCCEEEEEEHHHHCCCCCEEEHHHHHHHHHHHHCCC
PFFSLLFLAGAIGYLGYSIEQVAKEEIKKIETVSQEKTQEKKPENYIKEISVEAIQVELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
RDLLPLVDASSGGHLLEQIANTRKKFAIDFGLVIPAIRIIDNLEIPHDNYSIRINGVVVG
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC
QSAVRADRLMAMNNTTRNLEAIIGEPFTEPAFGLKATWIDPNDKIEVENKGYSVVDPSTV
CHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCEEECCCCCEEECCHHH
IITHLKELISNYASQLLGREEVKALLEHLRQTHPTLVGELDYDKQGRLGIIQQTLQNLLA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHH
EGLSIKNLPKIMDAIANHLPRTNNPFDLAEHVRQALSRQIINDFLSPDGKLHVVTIDPRI
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHH
IDRMNKSITLDETDGSKLIILPHDVRVRILESVYNELQKALDENRFLIFVVSRYLRQAFA
HHHCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
FFLTKELPPRNFAVIASEEIHRGVPTEIASVLSLPSREEHPQEA
HHHHHCCCCCCEEEEECHHHHCCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]