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The map label for this gene is 183221843

Identifier: 183221843

GI number: 183221843

Start: 2557463

End: 2558125

Strand: Reverse

Name: 183221843

Synonym: LEPBI_I2474

Alternate gene names: NA

Gene position: 2558125-2557463 (Counterclockwise)

Preceding gene: 183221845

Following gene: 183221841

Centisome position: 71.07

GC content: 34.54

Gene sequence:

>663_bases
TTGGTGATTAAAAAAAAGAATCAGAAATTGAAAAAACAACTTTCGAAGGATGTTTTGGTCCAAACTGCCATTTCATTTGC
AGACAAAAATGGAATCGATTCTCTTTCTATGCGAAATTTGGCGCAATTGTTAGGTGTGGAAGCCATGTCATTGTACAATC
ATATCCAAAACAAAGATGAACTAATCGATGGTATGGTAGAATCGTGTGTAATACTTTTTAGTTTACCAAAAGTAAAAGGT
CAGTGGAAAAAGGAAATGAAAAGGAGGGCAAGATCGGTAAGAGAAGTTCTTTTGAGCCACCCTTGGCTCACCATATTACT
TGTCTCTAGGGTGAATATTGGTGAAAGTATGCTTCGGTATTTTAATGATTCCATTGGTTGTTTGGTAAACGCCGGTTTTA
CATATAAACAAGCAGACCAAATCATCAACGCCATTGATAGTCATATTTATGGATTCACCTTGCAAGAGTTAAATTTTCCA
TTTAAACCTAATGAGTATAAATCTAAAGCGAGTGAATATTTGCCTATGATTCCCAAAAATGATCTAATTTATTTTTATAA
CCTAACCAAGGAAGTGGCTATGGGTAAGTACAACGGAAAACAAAACTTTGATTTTGGATTGGATTTAATCCTAGATGGAC
TCAAGTTCCAATCCAAAAAATGA

Upstream 100 bases:

>100_bases
ATATATTTCCTTAAAAATGAAAATTTTGTCTCGATCAGTAGTGAATTTTATGATAGATAAATGAGATATGCTGACAAACT
TTTAGGAGCAATTCAGAAAT

Downstream 100 bases:

>100_bases
AGAAAATTTAGATGGCGAAGACCGATTGGAATGTGAAAAAACTCGCATTCGGTTTGAAATCATACCTTCTGTATGGATCT
GTTTCATAAGGATTGTTCTT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MVIKKKNQKLKKQLSKDVLVQTAISFADKNGIDSLSMRNLAQLLGVEAMSLYNHIQNKDELIDGMVESCVILFSLPKVKG
QWKKEMKRRARSVREVLLSHPWLTILLVSRVNIGESMLRYFNDSIGCLVNAGFTYKQADQIINAIDSHIYGFTLQELNFP
FKPNEYKSKASEYLPMIPKNDLIYFYNLTKEVAMGKYNGKQNFDFGLDLILDGLKFQSKK

Sequences:

>Translated_220_residues
MVIKKKNQKLKKQLSKDVLVQTAISFADKNGIDSLSMRNLAQLLGVEAMSLYNHIQNKDELIDGMVESCVILFSLPKVKG
QWKKEMKRRARSVREVLLSHPWLTILLVSRVNIGESMLRYFNDSIGCLVNAGFTYKQADQIINAIDSHIYGFTLQELNFP
FKPNEYKSKASEYLPMIPKNDLIYFYNLTKEVAMGKYNGKQNFDFGLDLILDGLKFQSKK
>Mature_220_residues
MVIKKKNQKLKKQLSKDVLVQTAISFADKNGIDSLSMRNLAQLLGVEAMSLYNHIQNKDELIDGMVESCVILFSLPKVKG
QWKKEMKRRARSVREVLLSHPWLTILLVSRVNIGESMLRYFNDSIGCLVNAGFTYKQADQIINAIDSHIYGFTLQELNFP
FKPNEYKSKASEYLPMIPKNDLIYFYNLTKEVAMGKYNGKQNFDFGLDLILDGLKFQSKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR004111
- InterPro:   IPR001647 [H]

Pfam domain/function: PF02909 TetR_C; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25268; Mature: 25268

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIKKKNQKLKKQLSKDVLVQTAISFADKNGIDSLSMRNLAQLLGVEAMSLYNHIQNKDE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LIDGMVESCVILFSLPKVKGQWKKEMKRRARSVREVLLSHPWLTILLVSRVNIGESMLRY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
FNDSIGCLVNAGFTYKQADQIINAIDSHIYGFTLQELNFPFKPNEYKSKASEYLPMIPKN
HCCCHHHEEECCCCHHHHHHHHHHHHHHHHCEEHHHCCCCCCCCHHHHHHHHHCCCCCCC
DLIYFYNLTKEVAMGKYNGKQNFDFGLDLILDGLKFQSKK
CEEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVIKKKNQKLKKQLSKDVLVQTAISFADKNGIDSLSMRNLAQLLGVEAMSLYNHIQNKDE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LIDGMVESCVILFSLPKVKGQWKKEMKRRARSVREVLLSHPWLTILLVSRVNIGESMLRY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
FNDSIGCLVNAGFTYKQADQIINAIDSHIYGFTLQELNFPFKPNEYKSKASEYLPMIPKN
HCCCHHHEEECCCCHHHHHHHHHHHHHHHHCEEHHHCCCCCCCCHHHHHHHHHCCCCCCC
DLIYFYNLTKEVAMGKYNGKQNFDFGLDLILDGLKFQSKK
CEEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]