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The map label for this gene is ttuD [H]

Identifier: 183221825

GI number: 183221825

Start: 2537719

End: 2538906

Strand: Reverse

Name: ttuD [H]

Synonym: LEPBI_I2456

Alternate gene names: 183221825

Gene position: 2538906-2537719 (Counterclockwise)

Preceding gene: 183221826

Following gene: 183221823

Centisome position: 70.53

GC content: 36.53

Gene sequence:

>1188_bases
TTGAATTCACTCAAAGAAGAAATTTTGTATTTTTTTAGACTAGGGGTACATGCGGCGGACCCCAATTCCTTGTTTGAAGA
TTTTTGGGAGGATCATTCGCTTTTACAGGAAACTTTCCATACTTCTAAAAAGAATTTGTTTGTCTTTTCAGTTGGAAAAG
CCGCGTATCCCATGGCGATGTCATTTGTTCATGATTTCCCAATTAAAAATGGTTATATTCTCACAAAGTACGGACATTTA
CCAACCGAAAAACAAATCATCCAAGAAGACTCAATTTGGAAGTATCGAGAAGCTTCCCATCCTATTCTTGATCAAAATTC
AATCGATCATTCAAATGAAGTCTTAAATTTATTAAAACAATTAGGAAAAAACGATCGTTTGGTGGTTCTTCTCTCTGGTG
GCGCATCTAGTTTGTTTGAAATACCTATCGAGGGTTATTCGTTAATTGATATGATCTCCATTCAAAAACGATTGTTAAAC
AGTGGTAAATTCATTCATGAGATCAATTTAGAGAGAAAAAAGTCTTCCAAGGTAAAAGGAGGAAAACTTTTATCAGAGTT
AAACTCAGAGTTAGAGGTGTATACGTTTGTGATCTCAGATGTCATTGGTGATGACCCATATACAATTGGTTCAGGGCCTA
CGTATCCTAGTGAAAATTATTTCATTTTGGGAAACCTCACAAAATCAATTCAAACCATTATACATAAAGCAAAACAACTA
GGATACCAAACGAAATGTATCAGTGATACTTGGACGGGTAGTGTTGAAGAAACATCATATTTGATTGAAAAAGAATTTTT
GTCTGCAATCGAATCAAATACAAAACAAATGGTTCTAATCGGTGGTGAATTGGTTTGCCCTGTGAATGGAAATGGAGTGG
GTGGAAGGAACCAAGAACTAGCCCTTCGGATAACCATCTTACTTGAAAAACACCAAGTCAATCGAAACTGGATGTTTTTA
TCGGCTGGCACTGATGGTACGGATGGCCCGACAGATGCTGCGGGCGGTGTTGTTACGAACAATACAATTGCCTTGATGAA
AGAAAAAAAATGGGATCCAATAGTTCAATTGGAAGATTCAAATTCTTATCCAATTCTAAAAGATGTAAATGCACTCGTTA
TGACAGGACCCACTGGTACGAATGTCAATGACATATTAATCTTGTTAGTTGAAGGTTCGGAATCCTAG

Upstream 100 bases:

>100_bases
TGTGTATCTCTTTGTCCTACTGATGTTCTACAATTTGGAAAATTGAATGGGAATCAGGTGACATTTGATTTGTTAGATGC
CAAAATGCGGAAATAATAGT

Downstream 100 bases:

>100_bases
ATTTGAATTCTGCCCACTCCAATAGATTTGGAACAACGGATTTTGCCATCTACTACTTCCAATTTTTGACGCTAATAACT
CATCGTCGATTTGTTTTAGG

Product: putative hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNSLKEEILYFFRLGVHAADPNSLFEDFWEDHSLLQETFHTSKKNLFVFSVGKAAYPMAMSFVHDFPIKNGYILTKYGHL
PTEKQIIQEDSIWKYREASHPILDQNSIDHSNEVLNLLKQLGKNDRLVVLLSGGASSLFEIPIEGYSLIDMISIQKRLLN
SGKFIHEINLERKKSSKVKGGKLLSELNSELEVYTFVISDVIGDDPYTIGSGPTYPSENYFILGNLTKSIQTIIHKAKQL
GYQTKCISDTWTGSVEETSYLIEKEFLSAIESNTKQMVLIGGELVCPVNGNGVGGRNQELALRITILLEKHQVNRNWMFL
SAGTDGTDGPTDAAGGVVTNNTIALMKEKKWDPIVQLEDSNSYPILKDVNALVMTGPTGTNVNDILILLVEGSES

Sequences:

>Translated_395_residues
MNSLKEEILYFFRLGVHAADPNSLFEDFWEDHSLLQETFHTSKKNLFVFSVGKAAYPMAMSFVHDFPIKNGYILTKYGHL
PTEKQIIQEDSIWKYREASHPILDQNSIDHSNEVLNLLKQLGKNDRLVVLLSGGASSLFEIPIEGYSLIDMISIQKRLLN
SGKFIHEINLERKKSSKVKGGKLLSELNSELEVYTFVISDVIGDDPYTIGSGPTYPSENYFILGNLTKSIQTIIHKAKQL
GYQTKCISDTWTGSVEETSYLIEKEFLSAIESNTKQMVLIGGELVCPVNGNGVGGRNQELALRITILLEKHQVNRNWMFL
SAGTDGTDGPTDAAGGVVTNNTIALMKEKKWDPIVQLEDSNSYPILKDVNALVMTGPTGTNVNDILILLVEGSES
>Mature_395_residues
MNSLKEEILYFFRLGVHAADPNSLFEDFWEDHSLLQETFHTSKKNLFVFSVGKAAYPMAMSFVHDFPIKNGYILTKYGHL
PTEKQIIQEDSIWKYREASHPILDQNSIDHSNEVLNLLKQLGKNDRLVVLLSGGASSLFEIPIEGYSLIDMISIQKRLLN
SGKFIHEINLERKKSSKVKGGKLLSELNSELEVYTFVISDVIGDDPYTIGSGPTYPSENYFILGNLTKSIQTIIHKAKQL
GYQTKCISDTWTGSVEETSYLIEKEFLSAIESNTKQMVLIGGELVCPVNGNGVGGRNQELALRITILLEKHQVNRNWMFL
SAGTDGTDGPTDAAGGVVTNNTIALMKEKKWDPIVQLEDSNSYPILKDVNALVMTGPTGTNVNDILILLVEGSES

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=445, Percent_Identity=26.2921348314607, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI193205461, Length=351, Percent_Identity=29.6296296296296, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19920578, Length=483, Percent_Identity=28.7784679089027, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43995; Mature: 43995

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLKEEILYFFRLGVHAADPNSLFEDFWEDHSLLQETFHTSKKNLFVFSVGKAAYPMAM
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
SFVHDFPIKNGYILTKYGHLPTEKQIIQEDSIWKYREASHPILDQNSIDHSNEVLNLLKQ
HHHHHCCCCCCEEEEECCCCCCHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHH
LGKNDRLVVLLSGGASSLFEIPIEGYSLIDMISIQKRLLNSGKFIHEINLERKKSSKVKG
HCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCH
GKLLSELNSELEVYTFVISDVIGDDPYTIGSGPTYPSENYFILGNLTKSIQTIIHKAKQL
HHHHHHHCCCCEEHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHC
GYQTKCISDTWTGSVEETSYLIEKEFLSAIESNTKQMVLIGGELVCPVNGNGVGGRNQEL
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCEE
ALRITILLEKHQVNRNWMFLSAGTDGTDGPTDAAGGVVTNNTIALMKEKKWDPIVQLEDS
EEEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEECC
NSYPILKDVNALVMTGPTGTNVNDILILLVEGSES
CCCCCHHCCCEEEEECCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure
MNSLKEEILYFFRLGVHAADPNSLFEDFWEDHSLLQETFHTSKKNLFVFSVGKAAYPMAM
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
SFVHDFPIKNGYILTKYGHLPTEKQIIQEDSIWKYREASHPILDQNSIDHSNEVLNLLKQ
HHHHHCCCCCCEEEEECCCCCCHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHH
LGKNDRLVVLLSGGASSLFEIPIEGYSLIDMISIQKRLLNSGKFIHEINLERKKSSKVKG
HCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCH
GKLLSELNSELEVYTFVISDVIGDDPYTIGSGPTYPSENYFILGNLTKSIQTIIHKAKQL
HHHHHHHCCCCEEHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHC
GYQTKCISDTWTGSVEETSYLIEKEFLSAIESNTKQMVLIGGELVCPVNGNGVGGRNQEL
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCEE
ALRITILLEKHQVNRNWMFLSAGTDGTDGPTDAAGGVVTNNTIALMKEKKWDPIVQLEDS
EEEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEECC
NSYPILKDVNALVMTGPTGTNVNDILILLVEGSES
CCCCCHHCCCEEEEECCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]