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The map label for this gene is xerC [H]

Identifier: 183221814

GI number: 183221814

Start: 2519737

End: 2520672

Strand: Reverse

Name: xerC [H]

Synonym: LEPBI_I2445

Alternate gene names: 183221814

Gene position: 2520672-2519737 (Counterclockwise)

Preceding gene: 183221817

Following gene: 183221813

Centisome position: 70.02

GC content: 38.25

Gene sequence:

>936_bases
ATGACCCTGCCTGTCCTTGAAGTCCAAATTCCCGAACATTTTCCCCAAGTGATGGCGGATTTATTTCGCAGTTACCGTAC
CTATCTCAAGATTGAAAAAAATTACTCGGAACATACTCTTTTCGCTTACCTGCGGGATTTGAAGTTTTTCTTTGAATTTT
GCTTAAAGGAAGAGATTGATATTTTGAGTGTAGATGTTCTTGATGTTCGAGCCTATTTTGCAGATTTAAAATCTTCCAAA
AAACAGGACAAACGTACCCAAAGCCGTAAACTTTCATCTCTACGTACCTTTTATAAATTTTTATTTCGGGAAGAAAAAAT
CGGAGCCAATCCTATTTTACAAGTCAGCTTCCCAAAAACCAAAAAGAGATTACCTAAAAATTTTACACCCATAGAAACAG
AAGATATCTTAGATTATGAAGACCCCGAAAAAAAAGAAGTACTCGGCAAACGTGATAAAGCAATTGTTGAAGTTTTATAC
AGTACAGGCCTTCGAGTATTTGAGTTAGTCAATGCTAAGTTAAGTGATTTGAACGAAGAGTTAACATCCCTTAAAGTCAT
GGGAAAAAGGCGAAAGGAAAGATTTGTTTTTATTGGTCCCGAAGCAAAAGTTGCATTACAAGAGTATTTGGATGAAAGAG
GCAATGGTGGCCCCGAAGAGATTTTTTTAAATCAAAGAGGTGGAAAATTGACCACTCGTGGCATCCGATACATTTTATCC
GAAAGAAGGTCAGTGATGGGTATGGAAAAAGCCATCACTCCCCATAAATTTAGACATACGTTTGCAACAGACTTACTTAA
TGCAGGAGCTGATATCCGCGCCGTACAAGAGTTACTTGGACATTCTTCCTTGTCATCAACGCAAGTGTATTTGAGTGTGT
CTCGTGATAGGTTGAAGGAAGTGTATCGAAATGCGCATCCTCACGCAAAGAAGTAG

Upstream 100 bases:

>100_bases
TGTCTTTTTTTTTCCGATTTCAACACTAAACAAAATGTAAGTACTTGTATAGTATTTTTTTAGAGAGGGAGAAAGAAAAC
TTAGCCGATAGTTTGGATGT

Downstream 100 bases:

>100_bases
GTGGGGCAATTGCGTGGGTATAGGATCCCCGCCCTGATTAGGGTGGGGAACTGAACCCGCCACCCAATACGCTCCTACTA
CCACACGATCTTCCTTTTTA

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTLPVLEVQIPEHFPQVMADLFRSYRTYLKIEKNYSEHTLFAYLRDLKFFFEFCLKEEIDILSVDVLDVRAYFADLKSSK
KQDKRTQSRKLSSLRTFYKFLFREEKIGANPILQVSFPKTKKRLPKNFTPIETEDILDYEDPEKKEVLGKRDKAIVEVLY
STGLRVFELVNAKLSDLNEELTSLKVMGKRRKERFVFIGPEAKVALQEYLDERGNGGPEEIFLNQRGGKLTTRGIRYILS
ERRSVMGMEKAITPHKFRHTFATDLLNAGADIRAVQELLGHSSLSSTQVYLSVSRDRLKEVYRNAHPHAKK

Sequences:

>Translated_311_residues
MTLPVLEVQIPEHFPQVMADLFRSYRTYLKIEKNYSEHTLFAYLRDLKFFFEFCLKEEIDILSVDVLDVRAYFADLKSSK
KQDKRTQSRKLSSLRTFYKFLFREEKIGANPILQVSFPKTKKRLPKNFTPIETEDILDYEDPEKKEVLGKRDKAIVEVLY
STGLRVFELVNAKLSDLNEELTSLKVMGKRRKERFVFIGPEAKVALQEYLDERGNGGPEEIFLNQRGGKLTTRGIRYILS
ERRSVMGMEKAITPHKFRHTFATDLLNAGADIRAVQELLGHSSLSSTQVYLSVSRDRLKEVYRNAHPHAKK
>Mature_310_residues
TLPVLEVQIPEHFPQVMADLFRSYRTYLKIEKNYSEHTLFAYLRDLKFFFEFCLKEEIDILSVDVLDVRAYFADLKSSKK
QDKRTQSRKLSSLRTFYKFLFREEKIGANPILQVSFPKTKKRLPKNFTPIETEDILDYEDPEKKEVLGKRDKAIVEVLYS
TGLRVFELVNAKLSDLNEELTSLKVMGKRRKERFVFIGPEAKVALQEYLDERGNGGPEEIFLNQRGGKLTTRGIRYILSE
RRSVMGMEKAITPHKFRHTFATDLLNAGADIRAVQELLGHSSLSSTQVYLSVSRDRLKEVYRNAHPHAKK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=289, Percent_Identity=37.3702422145329, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1790244, Length=290, Percent_Identity=36.2068965517241, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1790768, Length=161, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36206; Mature: 36075

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPVLEVQIPEHFPQVMADLFRSYRTYLKIEKNYSEHTLFAYLRDLKFFFEFCLKEEID
CCCCEEEEECHHHHHHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ILSVDVLDVRAYFADLKSSKKQDKRTQSRKLSSLRTFYKFLFREEKIGANPILQVSFPKT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
KKRLPKNFTPIETEDILDYEDPEKKEVLGKRDKAIVEVLYSTGLRVFELVNAKLSDLNEE
HHHCCCCCCCCCHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LTSLKVMGKRRKERFVFIGPEAKVALQEYLDERGNGGPEEIFLNQRGGKLTTRGIRYILS
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCCHHHHHHHHHHH
ERRSVMGMEKAITPHKFRHTFATDLLNAGADIRAVQELLGHSSLSSTQVYLSVSRDRLKE
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECHHHHHH
VYRNAHPHAKK
HHHCCCCCCCC
>Mature Secondary Structure 
TLPVLEVQIPEHFPQVMADLFRSYRTYLKIEKNYSEHTLFAYLRDLKFFFEFCLKEEID
CCCEEEEECHHHHHHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ILSVDVLDVRAYFADLKSSKKQDKRTQSRKLSSLRTFYKFLFREEKIGANPILQVSFPKT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
KKRLPKNFTPIETEDILDYEDPEKKEVLGKRDKAIVEVLYSTGLRVFELVNAKLSDLNEE
HHHCCCCCCCCCHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LTSLKVMGKRRKERFVFIGPEAKVALQEYLDERGNGGPEEIFLNQRGGKLTTRGIRYILS
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCCHHHHHHHHHHH
ERRSVMGMEKAITPHKFRHTFATDLLNAGADIRAVQELLGHSSLSSTQVYLSVSRDRLKE
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECHHHHHH
VYRNAHPHAKK
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA