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The map label for this gene is xerD [H]

Identifier: 183221728

GI number: 183221728

Start: 2426704

End: 2427612

Strand: Reverse

Name: xerD [H]

Synonym: LEPBI_I2357

Alternate gene names: 183221728

Gene position: 2427612-2426704 (Counterclockwise)

Preceding gene: 183221731

Following gene: 183221727

Centisome position: 67.44

GC content: 38.28

Gene sequence:

>909_bases
ATGGGTTCCAAATTGCCAGTTTCTCAAAATCAGCTTTTACAAACATTCCAAGAGTACCTGTCCGTAGAAAAAGGACTAAG
CGATAATTCGATTTATTCCTACGGATACGATCTCAACAAGTTCGCCATCTTTTTGGAAAAAGAACATATCAACTTCTTAG
AAGTAAAAGCCAATGACATCATGCGTTTTCTTGAAGAAGAGAGAGAACGTAAAATCTCAGCAAAAACACTTGCACGAGAA
GTTGTGGCAATCCGTCAGTTTTACAAATACCTAAGAGACGAAAAACGCCTCGATTCCAATCCAACGGAAAAAATTGAAAC
TCCTGAAGTCGCAAGGACAATCCCTGATTACCTTACACAGGCAGAAATCGAAGAATTATTTCGCAATATCAAAGAGGACA
ATTTGTACGAACTTCGTGACAAATGTATCTTTGAACTCCTTTACTCTTCAGGACTTCGGATCTCAGAAGCATGTAATTTG
AAAATGACTGATATCGATATGGAAAATATGACAATCACAGTAGAAGGAAAGGGAGGAAGACAACGCCTCGTTCCTTTTGG
TGAAAAGTCATTGGAAATCCTAAAACGATATTTGGTGGAAAGCCGGACAGAAATCCTCAAAAAAAGAACATGTGATTTTG
TATTTGTATCGAAGAAAGGGTCGTATATCAACCGTAAGTCGGTTTGGAGACTCCTAAACCATTACATCAAACGAACCAAA
ATTAAGAAAAAAGTCACACCACACACTCTTCGTCACTCATTTGCAACTCATCTATTGGAAAACCATGCAGATCTCAAATC
AGTGCAAGAGCTTCTCGGCCATATCGATATTTCGACGACACAGATTTATACCCATATGGCAAATAAAACTCTGAAGGAAG
TTCATAAGAAATTCCATCCGAGAGGATAA

Upstream 100 bases:

>100_bases
CACTTCTCCTTTTTTCCTGACATAGTCATTTGTGGCAAAAAAAATAATAAGTCTCTTTAAGCTTTTTGTCCGACTCTTTA
AGTAACATAAGAGAGTAAAG

Downstream 100 bases:

>100_bases
TGGTAAACCCTTCAAAACATGCGGACTACGGCAAAGTAGTCCGTATCCAAATTCCTTCAAACCCCAGATTTATTTCCCAC
ACTCGCAATTATTTTTTCCA

Product: tyrosine recombinase xerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MGSKLPVSQNQLLQTFQEYLSVEKGLSDNSIYSYGYDLNKFAIFLEKEHINFLEVKANDIMRFLEEERERKISAKTLARE
VVAIRQFYKYLRDEKRLDSNPTEKIETPEVARTIPDYLTQAEIEELFRNIKEDNLYELRDKCIFELLYSSGLRISEACNL
KMTDIDMENMTITVEGKGGRQRLVPFGEKSLEILKRYLVESRTEILKKRTCDFVFVSKKGSYINRKSVWRLLNHYIKRTK
IKKKVTPHTLRHSFATHLLENHADLKSVQELLGHIDISTTQIYTHMANKTLKEVHKKFHPRG

Sequences:

>Translated_302_residues
MGSKLPVSQNQLLQTFQEYLSVEKGLSDNSIYSYGYDLNKFAIFLEKEHINFLEVKANDIMRFLEEERERKISAKTLARE
VVAIRQFYKYLRDEKRLDSNPTEKIETPEVARTIPDYLTQAEIEELFRNIKEDNLYELRDKCIFELLYSSGLRISEACNL
KMTDIDMENMTITVEGKGGRQRLVPFGEKSLEILKRYLVESRTEILKKRTCDFVFVSKKGSYINRKSVWRLLNHYIKRTK
IKKKVTPHTLRHSFATHLLENHADLKSVQELLGHIDISTTQIYTHMANKTLKEVHKKFHPRG
>Mature_301_residues
GSKLPVSQNQLLQTFQEYLSVEKGLSDNSIYSYGYDLNKFAIFLEKEHINFLEVKANDIMRFLEEERERKISAKTLAREV
VAIRQFYKYLRDEKRLDSNPTEKIETPEVARTIPDYLTQAEIEELFRNIKEDNLYELRDKCIFELLYSSGLRISEACNLK
MTDIDMENMTITVEGKGGRQRLVPFGEKSLEILKRYLVESRTEILKKRTCDFVFVSKKGSYINRKSVWRLLNHYIKRTKI
KKKVTPHTLRHSFATHLLENHADLKSVQELLGHIDISTTQIYTHMANKTLKEVHKKFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=36.7697594501718, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=30.9278350515464, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1790767, Length=170, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=29.585798816568, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35570; Mature: 35438

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSKLPVSQNQLLQTFQEYLSVEKGLSDNSIYSYGYDLNKFAIFLEKEHINFLEVKANDI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCCCEEEECHHHH
MRFLEEERERKISAKTLAREVVAIRQFYKYLRDEKRLDSNPTEKIETPEVARTIPDYLTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
AEIEELFRNIKEDNLYELRDKCIFELLYSSGLRISEACNLKMTDIDMENMTITVEGKGGR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCEEEEEECCCCC
QRLVPFGEKSLEILKRYLVESRTEILKKRTCDFVFVSKKGSYINRKSVWRLLNHYIKRTK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
IKKKVTPHTLRHSFATHLLENHADLKSVQELLGHIDISTTQIYTHMANKTLKEVHKKFHP
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
RG
CC
>Mature Secondary Structure 
GSKLPVSQNQLLQTFQEYLSVEKGLSDNSIYSYGYDLNKFAIFLEKEHINFLEVKANDI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCCCEEEECHHHH
MRFLEEERERKISAKTLAREVVAIRQFYKYLRDEKRLDSNPTEKIETPEVARTIPDYLTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
AEIEELFRNIKEDNLYELRDKCIFELLYSSGLRISEACNLKMTDIDMENMTITVEGKGGR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCEEEEEECCCCC
QRLVPFGEKSLEILKRYLVESRTEILKKRTCDFVFVSKKGSYINRKSVWRLLNHYIKRTK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
IKKKVTPHTLRHSFATHLLENHADLKSVQELLGHIDISTTQIYTHMANKTLKEVHKKFHP
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA