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The map label for this gene is hslV

Identifier: 183221726

GI number: 183221726

Start: 2425693

End: 2426226

Strand: Reverse

Name: hslV

Synonym: LEPBI_I2355

Alternate gene names: 183221726

Gene position: 2426226-2425693 (Counterclockwise)

Preceding gene: 183221727

Following gene: 183221725

Centisome position: 67.4

GC content: 44.19

Gene sequence:

>534_bases
ATGGAAACAATTCACGCAACCACCATCCTATCCGTACGTAAAAACGGAAAAATCGCAGTTGGAGGGGATGGCCAAGTTTC
GATGGGAAATACCGTCATGAAACACACAGCAAAAAAAGTCCGTCGCCTTTACAATGGTAAGGTGATCGCAGGATTTGCAG
GGAGCGCTGCCGATGCATTTACTCTTTTTGAACTTTTTGAAAAAAAATTAATCGAACATGGCGGATCAGTTTCTCGTGCG
GCGGTGGAACTTGCCCGCGAATGGAGGATGGACCGGATGTTACGAAGGCTTGAGGCACTCCTCATCGTCTGTGATGCAAA
CGAATCCTTTCTCATTTCAGGGACAGGCGATGTGATTTCTCCCGATGATGGAGTGCTTGCGATTGGTTCTGGTGGCAATT
TTGCACTGAGTGCCGCAAGAGCCCTAGTGGAAAATACAGATTTAGATCCAAAAGAAATCATAACAAAGGCAATGAACATT
ACGGCTGACATTTGTATTTATACAAATCATAATTTGGTGATAGAGGAATTATAA

Upstream 100 bases:

>100_bases
TTAGACCAATCCTTCGAGATTGGAAACCAGATGGTCCTCATCAAAAGAAAGTAACCTCCATTTTTCTCGACAAAGCTTCC
TCATTTGGAAATTTATCCTT

Downstream 100 bases:

>100_bases
GATGAGTTTCAAAACAATACTTGCAGAAGTCGCAACCCAAGGTGAGGATCTAAACGAACTCACGCCACGCCAAATTGTAG
AGCGTTTGGATGAACACATC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
METIHATTILSVRKNGKIAVGGDGQVSMGNTVMKHTAKKVRRLYNGKVIAGFAGSAADAFTLFELFEKKLIEHGGSVSRA
AVELAREWRMDRMLRRLEALLIVCDANESFLISGTGDVISPDDGVLAIGSGGNFALSAARALVENTDLDPKEIITKAMNI
TADICIYTNHNLVIEEL

Sequences:

>Translated_177_residues
METIHATTILSVRKNGKIAVGGDGQVSMGNTVMKHTAKKVRRLYNGKVIAGFAGSAADAFTLFELFEKKLIEHGGSVSRA
AVELAREWRMDRMLRRLEALLIVCDANESFLISGTGDVISPDDGVLAIGSGGNFALSAARALVENTDLDPKEIITKAMNI
TADICIYTNHNLVIEEL
>Mature_177_residues
METIHATTILSVRKNGKIAVGGDGQVSMGNTVMKHTAKKVRRLYNGKVIAGFAGSAADAFTLFELFEKKLIEHGGSVSRA
AVELAREWRMDRMLRRLEALLIVCDANESFLISGTGDVISPDDGVLAIGSGGNFALSAARALVENTDLDPKEIITKAMNI
TADICIYTNHNLVIEEL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=63.7426900584795, Blast_Score=229, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_LEPBA (B0SCD1)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001963356.1
- ProteinModelPortal:   B0SCD1
- SMR:   B0SCD1
- MEROPS:   T01.007
- GeneID:   6388359
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_2285
- HOGENOM:   HBG288822
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- BioCyc:   LBIF355278:LBF_2285-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19076; Mature: 19076

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 7-7

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIHATTILSVRKNGKIAVGGDGQVSMGNTVMKHTAKKVRRLYNGKVIAGFAGSAADAF
CCCEEHEEEEEEECCCEEEECCCCCEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
TLFELFEKKLIEHGGSVSRAAVELAREWRMDRMLRRLEALLIVCDANESFLISGTGDVIS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCEEC
PDDGVLAIGSGGNFALSAARALVENTDLDPKEIITKAMNITADICIYTNHNLVIEEL
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEEECCCEEEEEC
>Mature Secondary Structure
METIHATTILSVRKNGKIAVGGDGQVSMGNTVMKHTAKKVRRLYNGKVIAGFAGSAADAF
CCCEEHEEEEEEECCCEEEECCCCCEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
TLFELFEKKLIEHGGSVSRAAVELAREWRMDRMLRRLEALLIVCDANESFLISGTGDVIS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCEEC
PDDGVLAIGSGGNFALSAARALVENTDLDPKEIITKAMNITADICIYTNHNLVIEEL
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA