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The map label for this gene is secY [H]

Identifier: 183221328

GI number: 183221328

Start: 2031485

End: 2032864

Strand: Reverse

Name: secY [H]

Synonym: LEPBI_I1945

Alternate gene names: 183221328

Gene position: 2032864-2031485 (Counterclockwise)

Preceding gene: 183221329

Following gene: 183221327

Centisome position: 56.47

GC content: 40.94

Gene sequence:

>1380_bases
ATGTTTCAAACCATCGCTAACATCTTTCGAATCCCGGAATTAAGATCTAAAATCCTATTTACGATCGGTATGTTGTTACT
TTTTAGAATGGGAACTCACGTGACCATTCCTGGTATCAACAGTTTGATTGTGACGGGCATTACTGCCGATCCAAGTGAAG
GTTTCCTTGGAATGGTGGATTTGTTTGCTGGTGGTGCTCTTCTCAAATTTTCTATTTTTGCATTAGGGATCATGCCTTAT
ATCTCTTCTTCCATCATCATGCAACTTGTGATGGTTCTCATTCCAAGTCTGCAAAAGATGCAAAAGGAAGGAGAAGAGGG
CAGAAAAAAGATCCAACAGTATACGAAGTACGGAACGCTCATCCTTTGTGCGATTCAGTCTCTTGCTGTGATCCAATTGG
CAAATTCTTGGTCTACTGGATCAGGAAACGCACAAGCCAAGTATCCTGGTCTTATCAATCCGTCAGTGGAAGGTTACTTT
TTACCAATTGCGATGCTTTCCATCACAACAGGGACTGTGCTTCTCATTTGGCTCGGGGAACAGATCACGGAACGAGGGAT
CGGAAACGGTATCTCTCTCATTATTTTCGCGGGTATCATTGGTCGTATGCCAGAAGCACTCATTGCGATGTTTACTTCTG
ATACTTCAGATGCGCTTAGCATTCTCATTCTCATCATCATCTTTATTGTTCTCATTTCCTTAACTGTGATTTTAACCCAA
GGGGTCCGCCGGGTACCATTGAATTATGGAAAACAAATGGTGGGTAGAAAGATGGTTCAGGCTCGTAGCCAATCCATCCC
TTTTAAAGTGAACAGTGCGAATGTAATGCCAATTATCTTTGCATCATCTTTGATTCTATTCCCACAAACAATTGTTCAGT
GGTTATCGTCGAAGGGTGGTCAATGGGCAGGTTGGGCTGTGATTATGGACTATTTTAATCCATTTTCACAAATCTGGTAC
CATGCTTTATTTTATTATGTGATTTATACTTCTCTCATCATCTTCTTTGCTTATTTTTATACAGCGATTCAGTTCAACCC
ACAAGAGTTAGCTGATAACTTAAAAAAATATGGTGGGTTCATTCCAGGAGTTCGTCCAGGAAGCCAAACCAAAGAAATGA
TTGAGAAAATTCTGAATCGAATCACCTTACCGGGTGCTCTTTTCCTTGCTGGTCTTGCTCTTGCTCCTTATCTTATCATT
AAATTCTTAAATCTCGGATCTAATACCGGTGGCGGAACTTTAGTGTATACATTCGGGGGAACTTCTCTACTCATTATGGT
GGGTGTGGCACTCGAAACCTTAAAACAGATCGAAGCCCAACTCCTCATGAGAAATTACGAAGGTTTCATGAAAAAGACTA
AAATCAAGGGAAGAGTGTAA

Upstream 100 bases:

>100_bases
GGATGCTTTTTCTGCCTCTGCAAAAGAGAAAATTGAAAAAGCAGGTGGAAAAGTCATCATCAGAGAAAAGAAAAAAGAAG
AGAAAAAAAACTAATTACCC

Downstream 100 bases:

>100_bases
CGAATGAAGAGACTCATATTTATGGGCCCTCCAGGTGCTGGAAAGGGAACACAAGCTGACATCATCAAAGAGAAATACAA
TATCCCTCAGATTTCCACAG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MFQTIANIFRIPELRSKILFTIGMLLLFRMGTHVTIPGINSLIVTGITADPSEGFLGMVDLFAGGALLKFSIFALGIMPY
ISSSIIMQLVMVLIPSLQKMQKEGEEGRKKIQQYTKYGTLILCAIQSLAVIQLANSWSTGSGNAQAKYPGLINPSVEGYF
LPIAMLSITTGTVLLIWLGEQITERGIGNGISLIIFAGIIGRMPEALIAMFTSDTSDALSILILIIIFIVLISLTVILTQ
GVRRVPLNYGKQMVGRKMVQARSQSIPFKVNSANVMPIIFASSLILFPQTIVQWLSSKGGQWAGWAVIMDYFNPFSQIWY
HALFYYVIYTSLIIFFAYFYTAIQFNPQELADNLKKYGGFIPGVRPGSQTKEMIEKILNRITLPGALFLAGLALAPYLII
KFLNLGSNTGGGTLVYTFGGTSLLIMVGVALETLKQIEAQLLMRNYEGFMKKTKIKGRV

Sequences:

>Translated_459_residues
MFQTIANIFRIPELRSKILFTIGMLLLFRMGTHVTIPGINSLIVTGITADPSEGFLGMVDLFAGGALLKFSIFALGIMPY
ISSSIIMQLVMVLIPSLQKMQKEGEEGRKKIQQYTKYGTLILCAIQSLAVIQLANSWSTGSGNAQAKYPGLINPSVEGYF
LPIAMLSITTGTVLLIWLGEQITERGIGNGISLIIFAGIIGRMPEALIAMFTSDTSDALSILILIIIFIVLISLTVILTQ
GVRRVPLNYGKQMVGRKMVQARSQSIPFKVNSANVMPIIFASSLILFPQTIVQWLSSKGGQWAGWAVIMDYFNPFSQIWY
HALFYYVIYTSLIIFFAYFYTAIQFNPQELADNLKKYGGFIPGVRPGSQTKEMIEKILNRITLPGALFLAGLALAPYLII
KFLNLGSNTGGGTLVYTFGGTSLLIMVGVALETLKQIEAQLLMRNYEGFMKKTKIKGRV
>Mature_459_residues
MFQTIANIFRIPELRSKILFTIGMLLLFRMGTHVTIPGINSLIVTGITADPSEGFLGMVDLFAGGALLKFSIFALGIMPY
ISSSIIMQLVMVLIPSLQKMQKEGEEGRKKIQQYTKYGTLILCAIQSLAVIQLANSWSTGSGNAQAKYPGLINPSVEGYF
LPIAMLSITTGTVLLIWLGEQITERGIGNGISLIIFAGIIGRMPEALIAMFTSDTSDALSILILIIIFIVLISLTVILTQ
GVRRVPLNYGKQMVGRKMVQARSQSIPFKVNSANVMPIIFASSLILFPQTIVQWLSSKGGQWAGWAVIMDYFNPFSQIWY
HALFYYVIYTSLIIFFAYFYTAIQFNPQELADNLKKYGGFIPGVRPGSQTKEMIEKILNRITLPGALFLAGLALAPYLII
KFLNLGSNTGGGTLVYTFGGTSLLIMVGVALETLKQIEAQLLMRNYEGFMKKTKIKGRV

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=448, Percent_Identity=42.4107142857143, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 50571; Mature: 50571

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTIANIFRIPELRSKILFTIGMLLLFRMGTHVTIPGINSLIVTGITADPSEGFLGMVD
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECCCCCCCCCHHHHHH
LFAGGALLKFSIFALGIMPYISSSIIMQLVMVLIPSLQKMQKEGEEGRKKIQQYTKYGTL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILCAIQSLAVIQLANSWSTGSGNAQAKYPGLINPSVEGYFLPIAMLSITTGTVLLIWLGE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEHHH
QITERGIGNGISLIIFAGIIGRMPEALIAMFTSDTSDALSILILIIIFIVLISLTVILTQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVRRVPLNYGKQMVGRKMVQARSQSIPFKVNSANVMPIIFASSLILFPQTIVQWLSSKGG
CHHHCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
QWAGWAVIMDYFNPFSQIWYHALFYYVIYTSLIIFFAYFYTAIQFNPQELADNLKKYGGF
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
IPGVRPGSQTKEMIEKILNRITLPGALFLAGLALAPYLIIKFLNLGSNTGGGTLVYTFGG
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
TSLLIMVGVALETLKQIEAQLLMRNYEGFMKKTKIKGRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFQTIANIFRIPELRSKILFTIGMLLLFRMGTHVTIPGINSLIVTGITADPSEGFLGMVD
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECCCCCCCCCHHHHHH
LFAGGALLKFSIFALGIMPYISSSIIMQLVMVLIPSLQKMQKEGEEGRKKIQQYTKYGTL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILCAIQSLAVIQLANSWSTGSGNAQAKYPGLINPSVEGYFLPIAMLSITTGTVLLIWLGE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEHHH
QITERGIGNGISLIIFAGIIGRMPEALIAMFTSDTSDALSILILIIIFIVLISLTVILTQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVRRVPLNYGKQMVGRKMVQARSQSIPFKVNSANVMPIIFASSLILFPQTIVQWLSSKGG
CHHHCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
QWAGWAVIMDYFNPFSQIWYHALFYYVIYTSLIIFFAYFYTAIQFNPQELADNLKKYGGF
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
IPGVRPGSQTKEMIEKILNRITLPGALFLAGLALAPYLIIKFLNLGSNTGGGTLVYTFGG
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
TSLLIMVGVALETLKQIEAQLLMRNYEGFMKKTKIKGRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10542330 [H]