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The map label for this gene is ccmA [H]

Identifier: 183221312

GI number: 183221312

Start: 2016756

End: 2017364

Strand: Reverse

Name: ccmA [H]

Synonym: LEPBI_I1929

Alternate gene names: 183221312

Gene position: 2017364-2016756 (Counterclockwise)

Preceding gene: 183221314

Following gene: 183221311

Centisome position: 56.04

GC content: 41.05

Gene sequence:

>609_bases
ATGAACCGAATGCTTTTGGAGACAAAAGGACTCACTATTACTGTCGGCGAAAAAACCATCCTGAGAGAGGTGAATCTTAG
TTTTTTTGAGAATGGCCTTTTCGCCGTCCTAGGTGAAAATGGCGCGGGAAAGTCCACTTTACTGAAAAAAATCTTCCATG
AAGCCTTAACCTCACCCGGTTGGCACTGGCCGAATGGAAAAAAGAAAATTGCCTACCTTGGCCATGAGCTTGGATTTTAC
TCCTCTTTAAGTTTAGAAGAAAATTTGGATTATTTTGCTAGTTTGGATGGAGCCCATTCGATCGAACGAAGGAACCAACT
TTTGAAATTGTTTCGATTGGAAAAACGGATTTGGGATCCCATCCATTTGTTTTCTCGTGGGATGAAACAGAAAGTAGCGA
TCATGAGGGTTTTACTTTCTTCTGCGGAAGTGATTCTATTCGACGAACCTTACACGGGTCTTGATTTTGATTCCGCAAAC
ATCCTCAGTAGAATTCTCAATGAAGAAAAAGGATCTAGACTCATCCTTGTTGTCCTCCATTCCATTCCCAATGAATTAGA
ATGTTCGGGGAAAATTTCCATTCAGCAGGGGAATGTTTTTGTTTCTTAG

Upstream 100 bases:

>100_bases
TCTGGGTATTCCTTGTTCCCGATTAGTTTTTGTCCCAATAGGAGAGTGGGGAATAAAAACAGAAGTGCGAATGTAAAGAG
TGAATGGAACATGGTGTAGA

Downstream 100 bases:

>100_bases
TCTGTTAAAAAAAGATTTTTATCTGATAGGAAGGTCCCTCGGTGGGATCGTTTCGCTTTTTACCTTAAGTGTTTCAGTCG
TTTTTATTTTTTATACTGCG

Product: heme exporter protein CcmA

Products: NA

Alternate protein names: Na(+) ABC transporter [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MNRMLLETKGLTITVGEKTILREVNLSFFENGLFAVLGENGAGKSTLLKKIFHEALTSPGWHWPNGKKKIAYLGHELGFY
SSLSLEENLDYFASLDGAHSIERRNQLLKLFRLEKRIWDPIHLFSRGMKQKVAIMRVLLSSAEVILFDEPYTGLDFDSAN
ILSRILNEEKGSRLILVVLHSIPNELECSGKISIQQGNVFVS

Sequences:

>Translated_202_residues
MNRMLLETKGLTITVGEKTILREVNLSFFENGLFAVLGENGAGKSTLLKKIFHEALTSPGWHWPNGKKKIAYLGHELGFY
SSLSLEENLDYFASLDGAHSIERRNQLLKLFRLEKRIWDPIHLFSRGMKQKVAIMRVLLSSAEVILFDEPYTGLDFDSAN
ILSRILNEEKGSRLILVVLHSIPNELECSGKISIQQGNVFVS
>Mature_202_residues
MNRMLLETKGLTITVGEKTILREVNLSFFENGLFAVLGENGAGKSTLLKKIFHEALTSPGWHWPNGKKKIAYLGHELGFY
SSLSLEENLDYFASLDGAHSIERRNQLLKLFRLEKRIWDPIHLFSRGMKQKVAIMRVLLSSAEVILFDEPYTGLDFDSAN
ILSRILNEEKGSRLILVVLHSIPNELECSGKISIQQGNVFVS

Specific function: Involved in ATP-dependent electrogenic sodium extrusion [H]

COG id: COG4555

COG function: function code CP; ABC-type Na+ transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI116734710, Length=177, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI48995001, Length=217, Percent_Identity=27.1889400921659, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788165, Length=164, Percent_Identity=27.4390243902439, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87081791, Length=218, Percent_Identity=25.2293577981651, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790467, Length=162, Percent_Identity=28.3950617283951, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48994943, Length=166, Percent_Identity=29.5180722891566, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87081709, Length=166, Percent_Identity=26.5060240963855, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081782, Length=164, Percent_Identity=25.609756097561, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643674, Length=217, Percent_Identity=23.963133640553, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 22819; Mature: 22819

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRMLLETKGLTITVGEKTILREVNLSFFENGLFAVLGENGAGKSTLLKKIFHEALTSPG
CCCCEEEECCCEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
WHWPNGKKKIAYLGHELGFYSSLSLEENLDYFASLDGAHSIERRNQLLKLFRLEKRIWDP
CCCCCCCCEEEEHHHHHCCCCCCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCH
IHLFSRGMKQKVAIMRVLLSSAEVILFDEPYTGLDFDSANILSRILNEEKGSRLILVVLH
HHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEH
SIPNELECSGKISIQQGNVFVS
HCCCCCCCCCEEEEECCCEEEC
>Mature Secondary Structure
MNRMLLETKGLTITVGEKTILREVNLSFFENGLFAVLGENGAGKSTLLKKIFHEALTSPG
CCCCEEEECCCEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
WHWPNGKKKIAYLGHELGFYSSLSLEENLDYFASLDGAHSIERRNQLLKLFRLEKRIWDP
CCCCCCCCEEEEHHHHHCCCCCCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCH
IHLFSRGMKQKVAIMRVLLSSAEVILFDEPYTGLDFDSANILSRILNEEKGSRLILVVLH
HHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEH
SIPNELECSGKISIQQGNVFVS
HCCCCCCCCCEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9106203; 9274031; 9384377 [H]