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The map label for this gene is purQ [H]

Identifier: 183221306

GI number: 183221306

Start: 2012498

End: 2013145

Strand: Reverse

Name: purQ [H]

Synonym: LEPBI_I1923

Alternate gene names: 183221306

Gene position: 2013145-2012498 (Counterclockwise)

Preceding gene: 183221307

Following gene: 183221305

Centisome position: 55.93

GC content: 41.82

Gene sequence:

>648_bases
ATGAAAGTTCGTGTTGTCACCTTTCCTGGTTCGAATTGTGATAAGGATGTTGGTTCTGTTTTACAGGAATCCTTCCAAGC
AGAAGTCATTTACACATGGTACAAAGAATCCTTTGAGGATGTTCCAGACCTTGTGGTTTTACCTGGAGGTTTTTCCTTCG
GTGATTACTTGCGATGCGGGGCCATGGCAAAATTTAGCCCGTCGATGGAATCAGTTGTGAAGTATGCGAATAAAGGTGGG
AAGGTTCTTGGAGTTTGTAATGGATTCCAAATTCTCACCGAATCAGGATTACTCCCTGGAGCATTATTACACAACAGGAC
ATTGAAATATATCTGTAAGGATGTGGAGCTTGTCCCAGTGAAAGAGAACAGCTTTGCAAAAAAAATGGAAGGAACTCTTT
CCATTCCCATTGCCCATGGGGAAGGTGCTTATTTTGCCGATCCAGAAACCTTAGAACGATTAGAAAAAAATGGGCAAGTC
GTATTCCGGTACAGGGAAAATCCAAATGGATCCTTACATGACATCGCAGGGATTTGTAATGAGAGGGGAAATGTTTTGGG
AATGATGCCTCACCCTGAACGAGCCATGAATCCTTATACAGGAAAAATGGACGGCAAACAAATCTTAGAAGCACTATTAA
AAAATTAG

Upstream 100 bases:

>100_bases
CTTCTTCTCAAAAAGAAGCAGAAGAAATTGCCAAAGGGATTTGTGAATCTGTGCTTGTGAACCAAGTGATTGAAACTTAC
AAACTAGTGGTTGAGTCTCA

Downstream 100 bases:

>100_bases
AATCTTCTTTTTCCTTTTCTTGCTTTTTCGTCTAATCCCATTATAAGGATAGGTATGAGATTCCAAGAAGACTCAATCGA
CTGTGTGGATTTTATCTTAA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKVRVVTFPGSNCDKDVGSVLQESFQAEVIYTWYKESFEDVPDLVVLPGGFSFGDYLRCGAMAKFSPSMESVVKYANKGG
KVLGVCNGFQILTESGLLPGALLHNRTLKYICKDVELVPVKENSFAKKMEGTLSIPIAHGEGAYFADPETLERLEKNGQV
VFRYRENPNGSLHDIAGICNERGNVLGMMPHPERAMNPYTGKMDGKQILEALLKN

Sequences:

>Translated_215_residues
MKVRVVTFPGSNCDKDVGSVLQESFQAEVIYTWYKESFEDVPDLVVLPGGFSFGDYLRCGAMAKFSPSMESVVKYANKGG
KVLGVCNGFQILTESGLLPGALLHNRTLKYICKDVELVPVKENSFAKKMEGTLSIPIAHGEGAYFADPETLERLEKNGQV
VFRYRENPNGSLHDIAGICNERGNVLGMMPHPERAMNPYTGKMDGKQILEALLKN
>Mature_215_residues
MKVRVVTFPGSNCDKDVGSVLQESFQAEVIYTWYKESFEDVPDLVVLPGGFSFGDYLRCGAMAKFSPSMESVVKYANKGG
KVLGVCNGFQILTESGLLPGALLHNRTLKYICKDVELVPVKENSFAKKMEGTLSIPIAHGEGAYFADPETLERLEKNGQV
VFRYRENPNGSLHDIAGICNERGNVLGMMPHPERAMNPYTGKMDGKQILEALLKN

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=195, Percent_Identity=31.2820512820513, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI48994899, Length=186, Percent_Identity=32.7956989247312, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321498, Length=181, Percent_Identity=37.0165745856354, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582111, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582109, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17137292, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23715; Mature: 23715

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRVVTFPGSNCDKDVGSVLQESFQAEVIYTWYKESFEDVPDLVVLPGGFSFGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCEEEECCCCCHHHHHHHC
AMAKFSPSMESVVKYANKGGKVLGVCNGFQILTESGLLPGALLHNRTLKYICKDVELVPV
CCCCCCCCHHHHHHHHCCCCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
KENSFAKKMEGTLSIPIAHGEGAYFADPETLERLEKNGQVVFRYRENPNGSLHDIAGICN
CCCCHHHHHCCEEEEEEECCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHC
ERGNVLGMMPHPERAMNPYTGKMDGKQILEALLKN
CCCCEEEECCCCHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKVRVVTFPGSNCDKDVGSVLQESFQAEVIYTWYKESFEDVPDLVVLPGGFSFGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCEEEECCCCCHHHHHHHC
AMAKFSPSMESVVKYANKGGKVLGVCNGFQILTESGLLPGALLHNRTLKYICKDVELVPV
CCCCCCCCHHHHHHHHCCCCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
KENSFAKKMEGTLSIPIAHGEGAYFADPETLERLEKNGQVVFRYRENPNGSLHDIAGICN
CCCCHHHHHCCEEEEEEECCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHC
ERGNVLGMMPHPERAMNPYTGKMDGKQILEALLKN
CCCCEEEECCCCHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA